IMP
Process View
The network for 'negative regulation of membrane potential' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of membrane potential
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Trp53 | transformation related protein 53 | 0.480 | |
| Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.215 | |
| Src | Rous sarcoma oncogene | 0.205 | |
| Mcl1 | myeloid cell leukemia sequence 1 | 0.163 | |
| Grxcr1 | glutaredoxin, cysteine rich 1 | 0.151 | |
| Srrm4 | serine/arginine repetitive matrix 4 | 0.111 | |
| Apoe | apolipoprotein E | 0.105 | |
| S1pr2 | sphingosine-1-phosphate receptor 2 | 0.105 | |
| Irak4 | interleukin-1 receptor-associated kinase 4 | 0.097 | |
| Atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.086 | |
| Kit | kit oncogene | 0.081 | |
| Pou4f3 | POU domain, class 4, transcription factor 3 | 0.080 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.079 | |
| Ednrb | endothelin receptor type B | 0.078 | |
| Myo6 | myosin VI | 0.072 | |
| Fbxw7 | F-box and WD-40 domain protein 7 | 0.070 | |
| Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 | 0.067 | |
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.062 | |
| Gfi1 | growth factor independent 1 | 0.062 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.052 | |
| Vim | vimentin | 0.049 | |
| Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.047 | |
| Ldb3 | LIM domain binding 3 | 0.046 | |
| Espn | espin | 0.043 | |
| Cacna1b | calcium channel, voltage-dependent, N type, alpha 1B subunit | 0.043 | |
| Mapk14 | mitogen-activated protein kinase 14 | 0.041 | |
| Trf | transferrin | 0.040 | |
| Tnfrsf11b | tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) | 0.038 | |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.037 | |
| Prkcc | protein kinase C, gamma | 0.036 | |
| Ina | internexin neuronal intermediate filament protein, alpha | 0.036 | |
| Thrb | thyroid hormone receptor beta | 0.036 | |
| S1pr3 | sphingosine-1-phosphate receptor 3 | 0.035 | |
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.034 | |
| Gad1 | glutamic acid decarboxylase 1 | 0.034 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.032 | |
| Cd22 | CD22 antigen | 0.032 | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.032 | |
| Sult4a1 | sulfotransferase family 4A, member 1 | 0.031 | |
| F7 | coagulation factor VII | 0.031 | |
| Cadps | Ca2+-dependent secretion activator | 0.031 | |
| Ctnnd2 | catenin (cadherin associated protein), delta 2 | 0.030 | |
| Cx3cr1 | chemokine (C-X3-C) receptor 1 | 0.030 | |
| Slc26a4 | solute carrier family 26, member 4 | 0.030 | |
| Cdk5r1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.029 | |
| Gad2 | glutamic acid decarboxylase 2 | 0.029 | |
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.028 | |
| Syt1 | synaptotagmin I | 0.028 | |
| Myt1l | myelin transcription factor 1-like | 0.027 | |
| Cplx2 | complexin 2 | 0.027 | |
| Syn2 | synapsin II | 0.027 | |
| Ush1g | Usher syndrome 1G homolog (human) | 0.026 | |
| Spock1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 | 0.026 | |
| Spib | Spi-B transcription factor (Spi-1/PU.1 related) | 0.025 | |
| Cntn3 | contactin 3 | 0.025 | |
| Mef2c | myocyte enhancer factor 2C | 0.025 | |
| Rgs17 | regulator of G-protein signaling 17 | 0.025 | |
| Actb | actin, beta | 0.025 | |
| Rit2 | Ras-like without CAAX 2 | 0.024 | |
| Plcb1 | phospholipase C, beta 1 | 0.023 | |
| Gabrb3 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 | 0.023 | |
| Prkca | protein kinase C, alpha | 0.023 | |
| Elavl3 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 0.023 | |
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.023 | |
| Rgs4 | regulator of G-protein signaling 4 | 0.023 | |
| Stmn4 | stathmin-like 4 | 0.022 | |
| Nap1l2 | nucleosome assembly protein 1-like 2 | 0.022 | |
| Mab21l2 | mab-21-like 2 (C. elegans) | 0.022 | |
| Cplx1 | complexin 1 | 0.022 | |
| Hcn1 | hyperpolarization-activated, cyclic nucleotide-gated K+ 1 | 0.021 | |
| Gpr37l1 | G protein-coupled receptor 37-like 1 | 0.021 | |
| Npc1 | Niemann Pick type C1 | 0.021 | |
| Elavl4 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) | 0.021 | |
| Gria2 | glutamate receptor, ionotropic, AMPA2 (alpha 2) | 0.021 | |
| Rgs14 | regulator of G-protein signaling 14 | 0.021 | |
| Btbd17 | BTB (POZ) domain containing 17 | 0.021 | |
| Asprv1 | aspartic peptidase, retroviral-like 1 | 0.021 | |
| Epha10 | Eph receptor A10 | 0.020 | |
| Nptx1 | neuronal pentraxin 1 | 0.020 | |
| Nell2 | NEL-like 2 (chicken) | 0.020 | |
| Sstr2 | somatostatin receptor 2 | 0.020 | |
| Cntn1 | contactin 1 | 0.020 | |
| Tmem198 | transmembrane protein 198 | 0.020 | |
| Rgs8 | regulator of G-protein signaling 8 | 0.020 | |
| Gal | galanin | 0.020 | |
| Ptprn | protein tyrosine phosphatase, receptor type, N | 0.020 | |
| Fbxo41 | F-box protein 41 | 0.019 | |
| Vgf | VGF nerve growth factor inducible | 0.019 | |
| Ifngr1 | interferon gamma receptor 1 | 0.019 | |
| Hs3st2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 0.019 | |
| Klf12 | Kruppel-like factor 12 | 0.019 | |
| Fus | fusion, derived from t(12;16) malignant liposarcoma (human) | 0.019 | |
| Myo7a | myosin VIIA | 0.019 | |
| Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.019 | |
| Snrk | SNF related kinase | 0.018 | |
| Rimbp2 | RIMS binding protein 2 | 0.018 | |
| Prkcb | protein kinase C, beta | 0.018 | |
| Il6st | interleukin 6 signal transducer | 0.018 | |
| Srms | src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites | 0.018 | |
| Gng3 | guanine nucleotide binding protein (G protein), gamma 3 | 0.018 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.746 | |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.282 | |
| DLG4 | discs, large homolog 4 (Drosophila) | 0.046 | |
| IL1R1 | interleukin 1 receptor, type I | 0.020 | |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.010 | |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.010 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Olr287 | olfactory receptor 287 | 0.079 | |
| Gjb4 | gap junction protein, beta 4 | 0.032 | |
| Opn1mw | opsin 1 (cone pigments), medium-wave-sensitive | 0.031 | |
| Olr442 | olfactory receptor 442 | 0.031 | |
| Insrr | insulin receptor-related receptor | 0.030 | |
| Uts2r | urotensin 2 receptor | 0.027 | |
| Mettl7b | methyltransferase like 7B | 0.026 | |
| Pyy | peptide YY (mapped) | 0.023 | |
| Htr3a | 5-hydroxytryptamine (serotonin) receptor 3a | 0.022 | |
| Pth | parathyroid hormone | 0.021 | |
| Car5a | carbonic anhydrase 5a, mitochondrial | 0.020 | |
| Adam18 | ADAM metallopeptidase domain 18 | 0.020 | |
| Tff3 | trefoil factor 3, intestinal | 0.019 | |
| Abcc6 | ATP-binding cassette, subfamily C (CFTR/MRP), member 6 | 0.019 | |
| Olr1500 | olfactory receptor 1500 | 0.017 | |
| Smr3a | submaxillary gland androgen regulated protein 3A | 0.016 | |
| Aqp2 | aquaporin 2 (collecting duct) | 0.015 | |
| Cyp4a10 | cytochrome P450, family 4, subfamily a, polypeptide 10 | 0.015 | |
| Spam1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) | 0.014 | |
| Sult2a1 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 0.014 | |
| Adora3 | adenosine A3 receptor | 0.014 | |
| Hal | histidine ammonia lyase | 0.014 | |
| Il1rn | interleukin 1 receptor antagonist | 0.013 | |
| Crhr2 | corticotropin releasing hormone receptor 2 | 0.012 | |
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.011 | |
| Olr1226 | olfactory receptor 1226 | 0.011 | |
| Dusp4 | dual specificity phosphatase 4 | 0.010 |