The network for 'metanephric comma shaped body morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

metanephric comma shaped body morphogenesis

The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.

Rattus norvegicus
Name Description Probability Func Analog Organism
Flt1 FMS-related tyrosine kinase 1 0.393
Sbp spermine binding protein 0.207
Gata3 GATA binding protein 3 0.199
Tpo thyroid peroxidase 0.188
Vwf von Willebrand factor 0.174
Hoxb7 homeo box B7 0.146
Sox17 SRY (sex determining region Y)-box 17 0.127
Efna5 ephrin A5 0.118
Gpr116 G protein-coupled receptor 116 0.116
Igf2 insulin-like growth factor 2 0.111
Emr1 EGF-like module containing, mucin-like, hormone receptor-like 1 0.106
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.099
C1qa complement component 1, q subcomponent, A chain 0.089
Pdha2 pyruvate dehydrogenase (lipoamide) alpha 2 0.088
MGC112715 hypothetical protein LOC690899 0.075
Ltbp3 latent transforming growth factor beta binding protein 3 0.073
Itpr3 inositol 1,4,5-triphosphate receptor, type 3 0.072
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.072
Gata6 GATA binding protein 6 0.071
Prph2 peripherin 2 0.068
Pdc phosducin 0.067
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.066
Lhx1 LIM homeobox 1 0.063
Cd4 Cd4 molecule 0.062
Robo1 roundabout homolog 1 (Drosophila) 0.061
Boc biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein 0.060
Nos3 nitric oxide synthase 3, endothelial cell 0.058
Akap14 A kinase (PRKA) anchor protein 14 0.052
Atp1a4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.052
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.051
Cmklr1 chemokine-like receptor 1 0.049
Adcy10 adenylate cyclase 10 (soluble) 0.048
Onecut1 one cut homeobox 1 0.048
Gper G protein-coupled estrogen receptor 1 0.047
Gjd2 gap junction protein, delta 2 0.047
Il1r1 interleukin 1 receptor, type I 0.046
Fbxo2 F-box protein 2 0.045
Spon1 spondin 1, extracellular matrix protein 0.043
Ager advanced glycosylation end product-specific receptor 0.043
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.042
Lama2 laminin, alpha 2 0.042
Lrp2 low density lipoprotein-related protein 2 0.042
Amh anti-Mullerian hormone 0.041
Srd5a2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 0.041
Fam65a family with sequence similarity 65, member A 0.040
Ggt5 gamma-glutamyltransferase 5 0.039
Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 0.039
Klk1c10 T-kininogenase 0.039
Bmp4 bone morphogenetic protein 4 0.038
Eps8 epidermal growth factor receptor pathway substrate 8 0.038
Cngb1 cyclic nucleotide gated channel beta 1 0.038
Hoxc4 homeo box C4 0.038
Ank2 ankyrin 2, neuronal 0.037
Pld4 phospholipase D family, member 4 0.036
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.036
Pecam1 platelet/endothelial cell adhesion molecule 1 0.036
Mylk2 myosin light chain kinase 2 0.036
Jag2 jagged 2 0.035
Lipe lipase, hormone sensitive 0.034
Cd68 Cd68 molecule 0.033
Grem1 gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) 0.033
Kcnc3 potassium voltage gated channel, Shaw-related subfamily, member 3 0.032
Unc5b unc-5 homolog B (C. elegans) 0.032
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.031
Shroom1 shroom family member 1 0.031
Egfl7 EGF-like-domain, multiple 7 0.031
Wipf1 WAS/WASL interacting protein family, member 1 0.030
Tal1 T-cell acute lymphocytic leukemia 1 0.030
Pou2f2 POU class 2 homeobox 2 0.030
Axl Axl receptor tyrosine kinase 0.030
Camk1g calcium/calmodulin-dependent protein kinase IG 0.029
Testin testin gene 0.029
Twist2 twist homolog 2 (Drosophila) 0.029
Ttn titin 0.029
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.029
Prss2 protease, serine, 2 0.028
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.028
Utrn utrophin 0.028
Six3 SIX homeobox 3 0.027
Epas1 endothelial PAS domain protein 1 0.027
RGD1564163 similar to RIKEN cDNA 1700025K23 0.027
B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 0.027
C1qtnf6 C1q and tumor necrosis factor related protein 6 0.027
Nrarp Notch-regulated ankyrin repeat protein 0.027
Mecp2 methyl CpG binding protein 2 0.026
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.026
Acvrl1 activin A receptor type II-like 1 0.026
Dchs1 dachsous 1 (Drosophila) 0.026
Hoxb8 homeo box B8 0.025
LOC100363145 stabilin 1 0.025
Col5a1 collagen, type V, alpha 1 0.025
Cdh5 cadherin 5 0.025
Foxc2 forkhead box C2 0.025
Mfhas1 malignant fibrous histiocytoma amplified sequence 1 0.024
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.024
Amelx amelogenin X chromosome 0.024
Tnr tenascin R 0.024
Angpt2 angiopoietin 2 0.024
Mpp3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.024
Timp3 TIMP metallopeptidase inhibitor 3 0.024
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
BMPR1A bone morphogenetic protein receptor, type IA 0.845
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.652
CAV1 caveolin 1, caveolae protein, 22kDa 0.238
MEOX1 mesenchyme homeobox 1 0.163
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.141
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.124
NKX2-1 NK2 homeobox 1 0.114
FSTL1 follistatin-like 1 0.056
PLCG1 phospholipase C, gamma 1 0.056
LAT linker for activation of T cells 0.047
PDGFA platelet-derived growth factor alpha polypeptide 0.037
PTEN phosphatase and tensin homolog 0.026
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.018
GAB1 GRB2-associated binding protein 1 0.017
EGFR epidermal growth factor receptor 0.017
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.017
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.016
SOS1 son of sevenless homolog 1 (Drosophila) 0.014
INSR insulin receptor 0.013
BCAR1 breast cancer anti-estrogen resistance 1 0.013
IGF1R insulin-like growth factor 1 receptor 0.013
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.012
NOG noggin 0.011
FRS2 fibroblast growth factor receptor substrate 2 0.011
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.011
PAX8 paired box 8 0.011
SLA Src-like-adaptor 0.011
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Pax2 paired box gene 2 1.000
Fgfr2 fibroblast growth factor receptor 2 0.999
Shh sonic hedgehog 0.999
Foxc1 forkhead box C1 0.998
Gli3 GLI-Kruppel family member GLI3 0.993
Foxc2 forkhead box C2 0.989
Fgfr1 fibroblast growth factor receptor 1 0.987
Emx2 empty spiracles homolog 2 (Drosophila) 0.980
Fgf8 fibroblast growth factor 8 0.965
Otx2 orthodenticle homolog 2 (Drosophila) 0.955
Tbx1 T-box 1 0.942
Rarb retinoic acid receptor, beta 0.927
Jag1 jagged 1 0.895
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.886
Eya1 eyes absent 1 homolog (Drosophila) 0.884
Lhx1 LIM homeobox protein 1 0.877
Pitx2 paired-like homeodomain transcription factor 2 0.868
Tgfb2 transforming growth factor, beta 2 0.862
Rarg retinoic acid receptor, gamma 0.835
Vegfa vascular endothelial growth factor A 0.835
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.810
Msx1 homeobox, msh-like 1 0.780
Hoxa1 homeobox A1 0.763
Sox9 SRY-box containing gene 9 0.715
Smo smoothened homolog (Drosophila) 0.682
Pax3 paired box gene 3 0.633
Rara retinoic acid receptor, alpha 0.623
Ctnnb1 catenin (cadherin associated protein), beta 1 0.622
Wnt9b wingless-type MMTV integration site 9B 0.544
Bmp4 bone morphogenetic protein 4 0.537
Rxra retinoid X receptor alpha 0.491
Tcfap2a transcription factor AP-2, alpha 0.465
Gbx2 gastrulation brain homeobox 2 0.423
Ret ret proto-oncogene 0.382
Bmp7 bone morphogenetic protein 7 0.370
Lhx9 LIM homeobox protein 9 0.365
Chd7 chromodomain helicase DNA binding protein 7 0.355
Vangl2 vang-like 2 (van gogh, Drosophila) 0.349
Bcl2 B-cell leukemia/lymphoma 2 0.347
Wt1 Wilms tumor 1 homolog 0.326
Otx1 orthodenticle homolog 1 (Drosophila) 0.314
Zeb1 zinc finger E-box binding homeobox 1 0.302
Ednra endothelin receptor type A 0.285
Prrx1 paired related homeobox 1 0.284
Gli2 GLI-Kruppel family member GLI2 0.229
Foxg1 forkhead box G1 0.228
Dlx5 distal-less homeobox 5 0.224
Fgf10 fibroblast growth factor 10 0.216
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.211
Pbx1 pre B-cell leukemia transcription factor 1 0.209
Osr1 odd-skipped related 1 (Drosophila) 0.196
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.195
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.193
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.180
Isl1 ISL1 transcription factor, LIM/homeodomain 0.170
Fgfr3 fibroblast growth factor receptor 3 0.159
Tgfbr2 transforming growth factor, beta receptor II 0.153
Meox2 mesenchyme homeobox 2 0.151
Lamc1 laminin, gamma 1 0.146
Pax6 paired box gene 6 0.117
Nos3 nitric oxide synthase 3, endothelial cell 0.114
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.111
Nab2 Ngfi-A binding protein 2 0.111
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.110
Sox2 SRY-box containing gene 2 0.102
Efnb2 ephrin B2 0.100
Hand2 heart and neural crest derivatives expressed transcript 2 0.099
Pten phosphatase and tensin homolog 0.097
Tcf21 transcription factor 21 0.097
Hoxa2 homeobox A2 0.094
Prrx2 paired related homeobox 2 0.083
Gata3 GATA binding protein 3 0.079
Apc adenomatosis polyposis coli 0.073
Bmper BMP-binding endothelial regulator 0.073
Hoxd11 homeobox D11 0.072
Ece1 endothelin converting enzyme 1 0.068
Ptgs2 prostaglandin-endoperoxide synthase 2 0.065
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.062
Sox4 SRY-box containing gene 4 0.061
Wnt4 wingless-related MMTV integration site 4 0.060
Nog noggin 0.053
Fos FBJ osteosarcoma oncogene 0.052
Lmx1a LIM homeobox transcription factor 1 alpha 0.051
Sox11 SRY-box containing gene 11 0.051
Acvr1 activin A receptor, type 1 0.050
Zic3 zinc finger protein of the cerebellum 3 0.049
Hand1 heart and neural crest derivatives expressed transcript 1 0.046
Gdnf glial cell line derived neurotrophic factor 0.045
Hoxa11 homeobox A11 0.045
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.042
Ptch1 patched homolog 1 0.041
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.036
Bmp2 bone morphogenetic protein 2 0.034
Runx2 runt related transcription factor 2 0.034
En1 engrailed 1 0.034
Jun Jun oncogene 0.033
Esr1 estrogen receptor 1 (alpha) 0.033
Gata4 GATA binding protein 4 0.032
Notch2 Notch gene homolog 2 (Drosophila) 0.032
Tbx10 T-box 10 0.031
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism