The network for 'response to transition metal nanoparticle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to transition metal nanoparticle

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle.

Rattus norvegicus
Name Description Probability Func Analog Organism
S100a6 S100 calcium binding protein A6 0.666
Ubb ubiquitin B 0.661
Cd14 CD14 molecule 0.590
Timp1 TIMP metallopeptidase inhibitor 1 0.580
S100a8 S100 calcium binding protein A8 0.489
COX2 COXII 0.466
Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 0.415
Slc30a2 solute carrier family 30 (zinc transporter), member 2 0.397
Trhr2 thyrotropin releasing hormone receptor 2 0.380
Ifitm3 interferon induced transmembrane protein 3 0.341
Mgp matrix Gla protein 0.337
Nefl neurofilament, light polypeptide 0.337
S100a9 S100 calcium binding protein A9 0.333
Akr1c18 aldo-keto reductase family 1, member C18 0.312
Ahsg alpha-2-HS-glycoprotein 0.309
Apoh apolipoprotein H (beta-2-glycoprotein I) 0.308
Alb albumin 0.303
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.292
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.288
Anxa1 annexin A1 0.279
Dhfr dihydrofolate reductase 0.274
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.270
Casp1 caspase 1 0.269
Mgst1 microsomal glutathione S-transferase 1 0.255
Krt5 keratin 5 0.249
Lgals3 lectin, galactoside-binding, soluble, 3 0.246
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.245
Musk muscle, skeletal, receptor tyrosine kinase 0.236
Anxa2 annexin A2 0.230
Prdx2 peroxiredoxin 2 0.225
Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 0.224
Anxa5 annexin A5 0.222
Serpina1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.218
Mag myelin-associated glycoprotein 0.217
Acadl acyl-Coenzyme A dehydrogenase, long-chain 0.214
Ifitm1 interferon induced transmembrane protein 1 0.213
Mmp8 matrix metallopeptidase 8 0.207
Mt2A metallothionein 2A 0.206
Aqp8 aquaporin 8 0.192
Abcc6 ATP-binding cassette, subfamily C (CFTR/MRP), member 6 0.190
Hpx hemopexin 0.189
Fga fibrinogen alpha chain 0.186
Urod uroporphyrinogen decarboxylase 0.185
Cpb2 carboxypeptidase B2 (plasma) 0.181
Tpt1 tumor protein, translationally-controlled 1 0.180
Cp ceruloplasmin 0.179
Nefm neurofilament, medium polypeptide 0.179
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.178
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.168
Ccl2 chemokine (C-C motif) ligand 2 0.165
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.163
Myl7 myosin, light chain 7, regulatory 0.161
Gjb3 gap junction protein, beta 3 0.159
S100a11 S100 calcium binding protein A11 (calizzarin) 0.157
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.156
Gnmt glycine N-methyltransferase 0.153
Casp2 caspase 2 0.149
Hrsp12 heat-responsive protein 12 0.146
Gc group specific component 0.145
RGD1562344 similar to Gm566 protein 0.144
Cdkn3 cyclin-dependent kinase inhibitor 3 0.143
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.142
Manea mannosidase, endo-alpha 0.139
Insrr insulin receptor-related receptor 0.138
Lgals1 lectin, galactoside-binding, soluble, 1 0.137
Stat3 signal transducer and activator of transcription 3 0.137
Fxyd1 FXYD domain-containing ion transport regulator 1 0.135
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.134
Apoa5 apolipoprotein A-V 0.134
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.134
Aldob aldolase B, fructose-bisphosphate 0.133
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.133
Gjb2 gap junction protein, beta 2 0.131
Ctsc cathepsin C 0.129
Sema6b sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 0.129
Kcne1 potassium voltage-gated channel, Isk-related family, member 1 0.128
LOC100363783 rCG53773-like 0.127
Kynu kynureninase (L-kynurenine hydrolase) 0.126
Apoa2 apolipoprotein A-II 0.126
Il8rb interleukin 8 receptor, beta 0.126
Hpd 4-hydroxyphenylpyruvate dioxygenase 0.124
S100b S100 calcium binding protein B 0.121
Lipf lipase, gastric 0.120
Ptprh protein tyrosine phosphatase, receptor type, H 0.120
Ramp1 receptor (G protein-coupled) activity modifying protein 1 0.120
Scg3 secretogranin III 0.119
Il12b interleukin 12B 0.119
ND2 NADH dehydrogenase subunit 2 0.118
Gstp1 glutathione S-transferase pi 1 0.118
Slfn2 schlafen 2 0.118
Mettl7b methyltransferase like 7B 0.118
Fgg fibrinogen gamma chain 0.118
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.118
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.118
Il18 interleukin 18 0.117
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.116
Apcs amyloid P component, serum 0.116
Mgst2 microsomal glutathione S-transferase 2 0.115
Neurl3 neuralized homolog 3 (Drosophila) 0.114
Plscr3 phospholipid scramblase 3 0.114
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
mig-2 Protein MIG-2 0.187
ttm-5 Protein TTM-5 0.125
ina-1 Protein INA-1 0.118
pek-1 Protein PEK-1 0.116
C32E8.3 Protein C32E8.3 0.075
kgb-1 Protein KGB-1 0.072
svh-2 Protein SVH-2 0.069
T27A3.1 Protein T27A3.1 0.065
mlk-1 Protein MLK-1 0.064
egl-44 Protein EGL-44 0.061
B0303.7 Protein B0303.7 0.057
unc-32 Protein UNC-32 0.050
pmk-3 Protein PMK-3 0.047
F13E6.1 Protein F13E6.1 0.045
gly-13 Protein GLY-13 0.045
cat-1 Protein CAT-1 0.042
B0507.2 Protein B0507.2 0.042
gcs-1 Protein GCS-1 0.037
tag-147 Protein TAG-147 0.036
egal-1 Protein EGAL-1 0.035
tes-1 Protein TES-1 0.033
K02G10.1 Protein K02G10.1 0.031
C03A3.2 Protein C03A3.2 0.030
ncs-2 Protein NCS-2 0.028
B0495.7 Protein B0495.7 0.028
alx-1 Protein ALX-1 0.028
K10B4.3 Protein K10B4.3 0.028
ppk-3 Protein PPK-3 0.028
sem-5 Protein SEM-5 0.026
tir-1 Protein TIR-1 0.025
upp-1 Protein UPP-1 0.024
C52B9.4 Protein C52B9.4 0.024
cst-2 Protein CST-2 0.024
pmk-1 Protein PMK-1 0.023
nhr-34 Protein NHR-34 0.022
C15C7.7 Protein C15C7.7 0.021
klf-3 Protein KLF-3 0.021
tps-1 Protein TPS-1 0.021
ced-3 Protein CED-3 0.020
CELE_Y47H9C.7 Protein Y47H9C.7 0.020
K10D6.4 Protein K10D6.4 0.020
sym-4 Protein SYM-4 0.019
egl-1 Protein EGL-1 0.019
acs-13 Protein ACS-13 0.019
syx-3 Protein SYX-3 0.018
CELE_C08F11.13 Protein C08F11.13 0.018
C35C5.3 Protein C35C5.3 0.018
CELE_D1054.5 Protein D1054.5 0.017
K05B2.2 Protein K05B2.2 0.017
sma-5 Protein SMA-5 0.017
cdc-42 Protein CDC-42 0.017
lon-2 Protein LON-2 0.017
F09A5.4 Protein F09A5.4 0.016
CELE_D2023.6 Protein D2023.6 0.016
smf-2 Protein SMF-2 0.016
lbp-9 Protein LBP-9 0.016
E02H9.3 Protein E02H9.3 0.016
cdf-1 Protein CDF-1 0.016
nhr-65 Protein NHR-65 0.016
C44C1.2 Protein C44C1.2 0.015
fat-1 Protein FAT-1 0.015
amph-1 Protein AMPH-1 0.015
CELE_H28G03.2 Protein H28G03.2 0.015
C06G8.3 Protein C06G8.3 0.015
unc-64 Protein UNC-64 0.015
F13E6.5 Protein F13E6.5 0.014
smf-1 Protein SMF-1 0.013
dmd-6 Protein DMD-6 0.013
mtch-1 Protein MTCH-1 0.013
dhs-30 Protein DHS-30 0.013
fncm-1 Protein FNCM-1 0.013
mpst-3 Protein MPST-3 0.012
ttyh-1 Protein TTYH-1 0.012
best-13 Protein BEST-13 0.012
erm-1 Protein ERM-1 0.012
C18E9.9 Protein C18E9.9 0.012
acl-5 Protein ACL-5 0.012
xpo-1 Protein XPO-1 0.012
C44H4.4 Protein C44H4.4 0.012
C49A9.5 Protein C49A9.5 0.011
exc-5 Protein EXC-5 0.011
F13E6.4 Protein F13E6.4 0.011
T23F4.2 Protein T23F4.2 0.011
nhr-154 Protein NHR-154 0.011
lpd-3 Protein LPD-3 0.011
sma-3 Protein SMA-3 0.011
CELE_C39H7.4 Protein C39H7.4 0.010
smf-3 Protein SMF-3 0.010
cst-1 Protein CST-1 0.010
acdh-11 Protein ACDH-11 0.010
F56D2.5 Protein F56D2.5 0.010
CELE_M03A8.3 Protein M03A8.3 0.010
glit-1 Protein GLIT-1 0.010
suox-1 Protein SUOX-1 0.010
F55A4.7 Protein F55A4.7 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
bcl2 B-cell leukemia/lymphoma 2 0.810
igfbp1a insulin-like growth factor binding protein 1a 0.698
mcl1a myeloid cell leukemia sequence 1a 0.637
ptgs2a prostaglandin-endoperoxide synthase 2a 0.548
sod1 superoxide dismutase 1, soluble 0.436
ca2 carbonic anhydrase II 0.418
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.384
baxa bcl2-associated X protein, a 0.379
bcl2l1 bcl2-like 1 0.372
gadd45aa growth arrest and DNA-damage-inducible, alpha, a 0.366
socs3a suppressor of cytokine signaling 3a 0.289
epas1b endothelial PAS domain protein 1b 0.262
bbc3 BCL2 binding component 3 0.258
acadm acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain 0.255
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.246
gadd45bb growth arrest and DNA-damage-inducible, beta b 0.236
LOC100000332 e3 ubiquitin-protein ligase RNF182-like 0.224
sod2 superoxide dismutase 2, mitochondrial 0.212
kcnh1 potassium voltage-gated channel, subfamily H (eag-related), member 1 0.211
atp7a ATPase, Cu++ transporting, alpha polypeptide 0.206
slc3a2 solute carrier family 3, member 2 0.204
inhbaa inhibin, beta Aa 0.204
cyp3c1 cytochrome P450, family 3, subfamily c, polypeptide 1 0.201
gpia glucose phosphate isomerase a 0.187
slc39a1 solute carrier family 39 (zinc transporter), member 1 0.186
dag1 dystroglycan 1 0.171
cebpd CCAAT/enhancer binding protein (C/EBP), delta 0.170
pdlim3b PDZ and LIM domain 3b 0.169
pdlim4 PDZ and LIM domain 4 0.168
fos v-fos FBJ murine osteosarcoma viral oncogene homolog 0.164
serpinb1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.163
hsp70 heat shock cognate 70-kd protein 0.162
slc9a8 solute carrier family 9 (sodium/hydrogen exchanger), member 8 0.160
npm4 nucleophosmin/nucleoplasmin, 4 0.148
prkcea protein kinase C, epsilon a 0.143
nfe2l2 nuclear factor (erythroid-derived 2)-like 2 0.142
bmp2b bone morphogenetic protein 2b 0.141
nrxn3a neurexin 3a 0.141
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.132
lgals9l1 lectin, galactoside-binding, soluble, 9 (galectin 9)-like 1 0.130
mtm1 myotubularin 1 0.130
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.129
mcl1b myeloid cell leukemia sequence 1b 0.120
cd63 Cd63 antigen 0.120
ripk2 receptor-interacting serine-threonine kinase 2 0.119
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.114
si:ch211-9d9.3 si:ch211-9d9.3 0.110
cyp3a65 cytochrome P450, family 3, subfamily A, polypeptide 65 0.110
map2k4b mitogen-activated protein kinase kinase 4b 0.109
acadl acyl-Coenzyme A dehydrogenase, long chain 0.108
slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 0.108
abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.107
rhag Rhesus blood group-associated glycoprotein 0.107
tgfbr2 transforming growth factor, beta receptor II 0.107
vps18 vacuolar protein sorting protein 18 0.105
s100a11 S100 calcium binding protein A11 0.104
LOC556849 ectonucleoside triphosphate diphosphohydrolase 5-like 0.102
gadd45ba growth arrest and DNA-damage-inducible, beta a 0.099
ptger4b prostaglandin E receptor 4 (subtype EP4) b 0.097
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.093
scn1a sodium channel, voltage-gated, type I, alpha 0.091
chac1 ChaC, cation transport regulator-like 1 0.090
hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit 0.088
bida BH3 interacting domain death agonist 0.087
prkcz protein kinase C, zeta 0.087
tlr3 toll-like receptor 3 0.086
atf3 activating transcription factor 3 0.084
zgc:112986 zgc:112986 0.084
acat1 acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) 0.082
slc4a1b solute carrier family 4, anion exchanger, member 1b 0.081
LOC557722 similar to transient receptor potential cation channel, subfamily M, member 5 0.079
LOC572430 e3 ubiquitin-protein ligase HACE1-like 0.079
mmp9 matrix metalloproteinase 9 0.078
col15a1a collagen, type XV, alpha 1a 0.078
nrg1 neuregulin 1 0.078
acsl3a acyl-CoA synthetase long-chain family member 3a 0.077
slc30a1 solute carrier family 30 (zinc transporter), member 1 0.077
atp1a1a.5 ATPase, Na+/K+ transporting, alpha 1a.5 polypeptide 0.076
adipor2 adiponectin receptor 2 0.074
tfr1a transferrin receptor 1a 0.073
rps15 ribosomal protein S15 0.072
flj13639 flj13639 0.070
igfbp1b insulin-like growth factor binding protein 1b 0.070
slc14a2 solute carrier family 14 (urea transporter), member 2 0.070
stc1l stanniocalcin 1, like 0.070
per2 period homolog 2 (Drosophila) 0.068
nt5e 5'-nucleotidase, ecto (CD73) 0.068
xbp1 X-box binding protein 1 0.066
rps26l ribosomal protein S26, like 0.065
ptgs2b prostaglandin-endoperoxide synthase 2b 0.064
pomca proopiomelanocortin a 0.063
rpl23a ribosomal protein L23a 0.063
pdlim5 PDZ and LIM domain 5 0.062
ctage5 CTAGE family, member 5 0.062
zgc:113210 zgc:113210 0.062
junb jun B proto-oncogene 0.061
hspa5 heat shock protein 5 0.059
sars seryl-tRNA synthetase 0.059
ptprf protein tyrosine phosphatase, receptor type, F 0.058
sult3st1 sulfotransferase family 3, cytosolic sulfotransferase 1 0.058
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Ugt35a UDP-glycosyltransferase 35a 0.710
Cat Catalase 0.422
Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2 0.272
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.133
Src42A Src oncogene at 42A 0.108
Fer1HCH Ferritin 1 heavy chain homologue 0.105
CG6283 CG6283 gene product from transcript CG6283-RA 0.090
NPFR1 neuropeptide F receptor 0.085
Adh Alcohol dehydrogenase 0.084
VhaM8.9 CG8444 gene product from transcript CG8444-RA 0.082
Cyp6a2 Cytochrome P450-6a2 0.062
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.060
Tpi Triose phosphate isomerase 0.051
Thor CG8846 gene product from transcript CG8846-RA 0.047
Cyp6g1 CG8453 gene product from transcript CG8453-RA 0.043
CG17325 CG17325 gene product from transcript CG17325-RA 0.040
porin CG6647 gene product from transcript CG6647-RA 0.040
Tequila CG4821 gene product from transcript CG4821-RE 0.038
Cyp12a5 CG11821 gene product from transcript CG11821-RA 0.037
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.034
CG14837 CG14837 gene product from transcript CG14837-RC 0.033
CG3371 CG3371 gene product from transcript CG3371-RA 0.033
Cyp9f2 CG11466 gene product from transcript CG11466-RB 0.032
Osi6 Osiris 6 0.030
Rel Relish 0.030
Jafrac1 thioredoxin peroxidase 1 0.029
CG1927 CG1927 gene product from transcript CG1927-RA 0.029
CG6277 CG6277 gene product from transcript CG6277-RA 0.026
Pabp2 CG2163 gene product from transcript CG2163-RA 0.026
TotA Turandot A 0.025
Yp3 Yolk protein 3 0.024
NAAT1 Nutrient Amino Acid Transporter 1 0.023
VhaPPA1-1 CG7007 gene product from transcript CG7007-RA 0.021
Cyp12b2 CG15077 gene product from transcript CG15077-RA 0.021
CG14196 CG14196 gene product from transcript CG14196-RA 0.021
CG11674 CG11674 gene product from transcript CG11674-RA 0.020
Psn Presenilin 0.020
plexB plexin B 0.020
LvpH Larval visceral protein H 0.019
mol moladietz 0.019
Cyp12e1 CG14680 gene product from transcript CG14680-RC 0.018
CG5639 CG5639 gene product from transcript CG5639-RA 0.018
Epac CG34392 gene product from transcript CG34392-RC 0.018
CG4389 CG4389 gene product from transcript CG4389-RA 0.017
Cyp6a9 Cytochrome P450-6a9 0.017
Sucb CG10622 gene product from transcript CG10622-RA 0.017
CG3759 CG3759 gene product from transcript CG3759-RB 0.017
Actr13E Actin-related protein 13E 0.016
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.015
CG1041 CG1041 gene product from transcript CG1041-RA 0.015
CG9053 CG9053 gene product from transcript CG9053-RA 0.015
CG6950 CG6950 gene product from transcript CG6950-RC 0.014
Amy-d Amylase distal 0.014
CG10361 CG10361 gene product from transcript CG10361-RA 0.014
wal walrus 0.013
Dcr-2 Dicer-2 0.013
CG17189 CG17189 gene product from transcript CG17189-RA 0.013
alpha-Est7 alpha-Esterase-7 0.012
ome omega 0.012
Tao-1 CG14217 gene product from transcript CG14217-RF 0.012
CG10824 CG10824 gene product from transcript CG10824-RA 0.012
Cyp4ac1 CG14032 gene product from transcript CG14032-RA 0.012
Tsp42Ed Tetraspanin 42Ed 0.012
CG10570 CG10570 gene product from transcript CG10570-RA 0.012
Cyp4d21 CG6730 gene product from transcript CG6730-RA 0.012
y yellow 0.011
Cyp6w1 CG8345 gene product from transcript CG8345-RA 0.011
Pxd Peroxidase 0.011
myoglianin CG1838 gene product from transcript CG1838-RD 0.011
drpr draper 0.011
CG15650 CG15650 gene product from transcript CG15650-RA 0.011
CG8690 CG8690 gene product from transcript CG8690-RA 0.010
ApepP Aminopeptidase P 0.010
CG7530 CG7530 gene product from transcript CG7530-RB 0.010
CG14935 CG14935 gene product from transcript CG14935-RA 0.010
CG10979 CG10979 gene product from transcript CG10979-RA 0.010
Gr43a Gustatory receptor 43a 0.010
Tsp29Fb Tetraspanin 29Fb 0.010
Exp6 Exportin 6 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
MT1E metallothionein 1E 0.999
MT1F metallothionein 1F 0.999
MT1X metallothionein 1X 0.999
MT2A metallothionein 2A 0.995
MT1H metallothionein 1H 0.990
MT1G metallothionein 1G 0.910
ABI2 abl-interactor 2 0.664
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.589
TP53 tumor protein p53 0.569
CDK2 cyclin-dependent kinase 2 0.565
APP amyloid beta (A4) precursor protein 0.530
BCL2 B-cell CLL/lymphoma 2 0.453
BCL2L1 BCL2-like 1 0.368
DLG4 discs, large homolog 4 (Drosophila) 0.280
IL1R1 interleukin 1 receptor, type I 0.273
IL1B interleukin 1, beta 0.247
PDZD11 PDZ domain containing 11 0.227
NAMPT nicotinamide phosphoribosyltransferase 0.224
CD300LD CD300 molecule-like family member d 0.207
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.179
LRP1 low density lipoprotein receptor-related protein 1 0.158
APOA1 apolipoprotein A-I 0.152
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.143
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.130
IL8 interleukin 8 0.129
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.126
CAV1 caveolin 1, caveolae protein, 22kDa 0.121
CCNE1 cyclin E1 0.119
BAD BCL2-associated agonist of cell death 0.116
MAPK14 mitogen-activated protein kinase 14 0.113
TICAM2 toll-like receptor adaptor molecule 2 0.113
KATNAL1 katanin p60 subunit A-like 1 0.112
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.108
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.098
DLG1 discs, large homolog 1 (Drosophila) 0.098
SPRY4 sprouty homolog 4 (Drosophila) 0.085
CXCL3 chemokine (C-X-C motif) ligand 3 0.082
BAK1 BCL2-antagonist/killer 1 0.081
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.079
GPR50 G protein-coupled receptor 50 0.078
BCL2A1 BCL2-related protein A1 0.070
MAPT microtubule-associated protein tau 0.070
PDLIM7 PDZ and LIM domain 7 (enigma) 0.069
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.069
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.068
ACVR1B activin A receptor, type IB 0.067
CDK6 cyclin-dependent kinase 6 0.065
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.062
DRD2 dopamine receptor D2 0.062
PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) 0.062
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.061
RB1 retinoblastoma 1 0.060
SKP2 S-phase kinase-associated protein 2 (p45) 0.058
FBLN5 fibulin 5 0.056
IL1RAP interleukin 1 receptor accessory protein 0.054
IL1RN interleukin 1 receptor antagonist 0.054
KCNJ5 potassium inwardly-rectifying channel, subfamily J, member 5 0.053
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.053
MT1M metallothionein 1M 0.050
BAX BCL2-associated X protein 0.050
BRCA2 breast cancer 2, early onset 0.049
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.046
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.046
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.045
IRS2 insulin receptor substrate 2 0.044
DUSP1 dual specificity phosphatase 1 0.043
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.041
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.040
ICAM1 intercellular adhesion molecule 1 0.039
PFN1 profilin 1 0.039
SSR1 signal sequence receptor, alpha 0.038
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.038
ADORA2A adenosine A2a receptor 0.037
MT1A metallothionein 1A 0.037
ADM adrenomedullin 0.037
SRGN serglycin 0.037
CCL20 chemokine (C-C motif) ligand 20 0.033
SH3D19 SH3 domain containing 19 0.033
MYD88 myeloid differentiation primary response gene (88) 0.033
FANCD2 Fanconi anemia, complementation group D2 0.032
MAP2K6 mitogen-activated protein kinase kinase 6 0.032
EGFR epidermal growth factor receptor 0.032
HIPK3 homeodomain interacting protein kinase 3 0.032
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.031
RIPK2 receptor-interacting serine-threonine kinase 2 0.030
PLAUR plasminogen activator, urokinase receptor 0.030
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.030
CFL1 cofilin 1 (non-muscle) 0.030
BID BH3 interacting domain death agonist 0.029
GSK3B glycogen synthase kinase 3 beta 0.029
CCNA2 cyclin A2 0.029
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.029
KCNJ11 potassium inwardly-rectifying channel, subfamily J, member 11 0.028
AGXT2 alanine--glyoxylate aminotransferase 2 0.028
TAGLN2 transgelin 2 0.028
NCOA1 nuclear receptor coactivator 1 0.028
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.027
USP50 ubiquitin specific peptidase 50 0.026
IL1R2 interleukin 1 receptor, type II 0.025
RNF144B ring finger protein 144B 0.025
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 1.000
Lyz2 lysozyme 2 0.813
Mt2 metallothionein 2 0.779
Trp53 transformation related protein 53 0.747
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.641
Ctnnb1 catenin (cadherin associated protein), beta 1 0.609
Mt1 metallothionein 1 0.594
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.561
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.547
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.541
Cd44 CD44 antigen 0.464
Pten phosphatase and tensin homolog 0.449
Cdk2 cyclin-dependent kinase 2 0.407
Nos3 nitric oxide synthase 3, endothelial cell 0.365
Apoe apolipoprotein E 0.346
Bglap bone gamma carboxyglutamate protein 0.308
Lepr leptin receptor 0.295
Fas Fas (TNF receptor superfamily member 6) 0.207
Lep leptin 0.196
Nos1 nitric oxide synthase 1, neuronal 0.168
Cp ceruloplasmin 0.160
Cps1 carbamoyl-phosphate synthetase 1 0.143
Fbp1 fructose bisphosphatase 1 0.133
Mmp9 matrix metallopeptidase 9 0.127
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.122
Cdk4 cyclin-dependent kinase 4 0.121
Il10 interleukin 10 0.117
Il1b interleukin 1 beta 0.114
Otc ornithine transcarbamylase 0.112
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.100
Apc adenomatosis polyposis coli 0.099
Alb albumin 0.097
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.097
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.095
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.087
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.086
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.084
Ccna2 cyclin A2 0.079
Slc2a5 solute carrier family 2 (facilitated glucose transporter), member 5 0.073
Tfrc transferrin receptor 0.073
Ar androgen receptor 0.072
Esr1 estrogen receptor 1 (alpha) 0.070
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.069
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.068
Steap3 STEAP family member 3 0.066
Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26 0.060
Rdh7 retinol dehydrogenase 7 0.060
Prnp prion protein 0.057
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.055
Foxn1 forkhead box N1 0.052
Spnb1 spectrin beta 1 0.050
Tdo2 tryptophan 2,3-dioxygenase 0.050
Col1a1 collagen, type I, alpha 1 0.049
Plg plasminogen 0.048
Ccl2 chemokine (C-C motif) ligand 2 0.048
Fos FBJ osteosarcoma oncogene 0.047
Tgfbr2 transforming growth factor, beta receptor II 0.046
Myd88 myeloid differentiation primary response gene 88 0.045
Vegfa vascular endothelial growth factor A 0.045
G6pc glucose-6-phosphatase, catalytic 0.044
Gc group specific component 0.043
Stat3 signal transducer and activator of transcription 3 0.042
Il1r1 interleukin 1 receptor, type I 0.040
Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.040
Serpind1 serine (or cysteine) peptidase inhibitor, clade D, member 1 0.039
Thrb thyroid hormone receptor beta 0.038
Brca1 breast cancer 1 0.037
Fga fibrinogen alpha chain 0.037
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.037
Serpina1a serine (or cysteine) peptidase inhibitor, clade A, member 1A 0.037
Azgp1 alpha-2-glycoprotein 1, zinc 0.036
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.034
Uox urate oxidase 0.034
Ambp alpha 1 microglobulin/bikunin 0.032
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.032
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.031
Akr1c6 aldo-keto reductase family 1, member C6 0.031
Mapk8 mitogen-activated protein kinase 8 0.031
Hfe hemochromatosis 0.030
Aldob aldolase B, fructose-bisphosphate 0.029
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.027
Pah phenylalanine hydroxylase 0.027
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.027
Itgb2 integrin beta 2 0.026
Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 0.025
Hr hairless 0.025
Cd4 CD4 antigen 0.025
Csf1 colony stimulating factor 1 (macrophage) 0.025
Ptgs1 prostaglandin-endoperoxide synthase 1 0.025
Irs1 insulin receptor substrate 1 0.024
Scp2 sterol carrier protein 2, liver 0.024
Il2rg interleukin 2 receptor, gamma chain 0.024
Tgfbr1 transforming growth factor, beta receptor I 0.023
Serpina1b serine (or cysteine) preptidase inhibitor, clade A, member 1B 0.023
Cd14 CD14 antigen 0.023
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 0.023
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.022
Ppl periplakin 0.022
Notch2 Notch gene homolog 2 (Drosophila) 0.022
Lcn2 lipocalin 2 0.022
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
AQY2 Aqy2p 0.222
YCR102C hypothetical protein 0.182
AFT1 Aft1p 0.123
CLB2 Clb2p 0.103
MIG1 Mig1p 0.094
CDC4 Cdc4p 0.081
CLB4 Clb4p 0.075
VID24 Vid24p 0.061
SIT1 Sit1p 0.059
MIG2 Mig2p 0.056
CLN1 Cln1p 0.054
YLR460C hypothetical protein 0.051
UFO1 Ufo1p 0.044
NDD1 Ndd1p 0.044
SGT1 Sgt1p 0.043
CLB1 Clb1p 0.040
POG1 Pog1p 0.036
MET30 Met30p 0.034
NRM1 Nrm1p 0.034
HSF1 Hsf1p 0.034
GRX4 Grx4p 0.033
HAL5 Hal5p 0.033
CKS1 Cks1p 0.033
CCS1 Ccs1p 0.032
ENB1 Enb1p 0.032
NRG1 Nrg1p 0.032
MCM1 Mcm1p 0.032
YKR075C hypothetical protein 0.031
MIG3 Mig3p 0.030
TSA2 Tsa2p 0.030
PRY2 Pry2p 0.029
HUG1 Hug1p 0.028
FKH1 Fkh1p 0.026
YNL134C hypothetical protein 0.026
OCH1 Och1p 0.026
DIA2 Dia2p 0.025
HXT3 Hxt3p 0.025
YPL014W hypothetical protein 0.024
SAP1 Sap1p 0.024
URA8 Ura8p 0.024
TPO2 Tpo2p 0.023
ROX1 Rox1p 0.022
MOB1 Mob1p 0.021
KIN3 Kin3p 0.021
RNR3 Rnr3p 0.021
YPR157W hypothetical protein 0.021
DAL81 Dal81p 0.021
SMF1 Smf1p 0.020
NUP157 Nup157p 0.020
SNF5 Snf5p 0.020
HOR2 Hor2p 0.020
SWI5 Swi5p 0.019
LYS5 Lys5p 0.019
HST3 Hst3p 0.019
ZRG17 Zrg17p 0.019
YNL234W hypothetical protein 0.018
CDC20 Cdc20p 0.018
LDB19 Ldb19p 0.018
KIC1 Kic1p 0.018
CUP9 Cup9p 0.018
SSK2 Ssk2p 0.018
SMF2 Smf2p 0.018
ZAP1 Zap1p 0.018
CTK3 Ctk3p 0.018
FAA2 Faa2p 0.018
PSK2 Psk2p 0.017
MSN1 Msn1p 0.017
CSI2 Csi2p 0.016
PUT4 Put4p 0.016
UNG1 Ung1p 0.016
RGS2 Rgs2p 0.016
FKH2 Fkh2p 0.016
YIR035C hypothetical protein 0.016
IRC23 Irc23p 0.016
ADY2 Ady2p 0.016
SKP2 Skp2p 0.016
TGL2 Tgl2p 0.016
TYE7 Tye7p 0.016
HHO1 Hho1p 0.016
YPK3 Ypk3p 0.016
CMD1 Cmd1p 0.016
SEY1 Sey1p 0.015
KTR5 Ktr5p 0.015
PCL5 Pcl5p 0.015
BNA5 Bna5p 0.015
STP4 Stp4p 0.015
SIM1 Sim1p 0.015
KIN4 Kin4p 0.015
HO Hop 0.015
RIM13 Rim13p 0.015
ICY1 Icy1p 0.015
BSD2 Bsd2p 0.014
YER130C hypothetical protein 0.014
NVJ1 Nvj1p 0.014
CSR2 Csr2p 0.014
YKL187C hypothetical protein 0.014
NCR1 Ncr1p 0.014
RUB1 Rub1p 0.014
SGF73 Sgf73p 0.014
UGP1 Ugp1p 0.014