The network for 'cell projection organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell projection organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.

Danio rerio
Name Description Probability Func Analog Organism
gli1 GLI-Kruppel family member 1 0.997
ift88 intraflagellar transport 88 homolog 0.996
shha sonic hedgehog a 0.994
lamc1 laminin, gamma 1 0.992
pax2a paired box gene 2a 0.991
flh floating head 0.978
arl13b ADP-ribosylation factor-like 13b 0.977
lamb1a laminin, beta 1a 0.972
ttna titin a 0.967
lrrc6 leucine rich repeat containing 6 0.965
pitx3 paired-like homeodomain transcription factor 3 0.964
dag1 dystroglycan 1 0.961
cdh2 cadherin 2, neuronal 0.951
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.948
pkd2 polycystic kidney disease 2 0.943
gdf6a growth differentiation factor 6a 0.934
fgf3 fibroblast growth factor 3 0.932
bmp4 bone morphogenetic protein 4 0.932
dmd dystrophin 0.928
olig2 oligodendrocyte lineage transcription factor 2 0.926
notch1a notch homolog 1a 0.923
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.919
cxcr4b chemokine (C-X-C motif), receptor 4b 0.919
dcc deleted in colorectal carcinoma 0.913
chd chordin 0.913
epb41l5 erythrocyte membrane protein band 4.1 like 5 0.901
gsna gelsolin a 0.896
robo2 roundabout homolog 2 0.877
ptpra protein tyrosine phosphatase, receptor type, A 0.876
oep one-eyed pinhead 0.873
nes nestin 0.871
gata2a GATA-binding protein 2a 0.871
flot1b flotillin 1b 0.870
dla deltaA 0.868
fgf8a fibroblast growth factor 8 a 0.864
tjp1 tight junction protein 1 (zona occludens 1) 0.862
slc17a6b solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b 0.855
spry4 sprouty (Drosophila) homolog 4 0.854
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.847
ift57 intraflagellar transport protein 57 0.846
sox1a SRY-box containing gene 1a 0.836
bambia BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a 0.830
hnf1ba HNF1 homeobox Ba 0.812
wnt11 wingless-type MMTV integration site family, member 11 0.811
disp1 dispatched homolog 1 (Drosophila) 0.811
fstl1b follistatin-like 1b 0.807
per3 period homolog 3 (Drosophila) 0.807
mbp myelin basic protein 0.805
wnt4a wingless-type MMTV integration site family, member 4a 0.803
foxn4 forkhead box N4 0.802
cc2d2a coiled-coil and C2 domain containing 2A 0.801
neurod neurogenic differentiation 0.800
camk2g1 calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1 0.799
nkx2.2a NK2 transcription factor related 2a 0.795
evx1 even-skipped homeobox 1 0.795
ptch2 patched 2 0.794
olfm2 olfactomedin 2 0.791
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.789
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.783
lhx1a LIM homeobox 1a 0.781
atoh1b atonal homolog 1b 0.777
sema3ab semaphorin 3ab 0.775
pink1 PTEN induced putative kinase 1 0.774
fgfr1a fibroblast growth factor receptor 1a 0.773
unc45b unc-45 homolog B (C. elegans) 0.773
tpbgl trophoblast glycoprotein-like 0.765
frem3 Fras1 related extracellular matrix 3 0.763
gyltl1b glycosyltransferase-like 1b 0.759
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.758
jag2 jagged 2 0.758
lrrc50 leucine rich repeat containing 50 0.758
fezf2 FEZ family zinc finger 2 0.757
wnt10a wingless-type MMTV integration site family, member 10a 0.756
pax7a paired box gene 7a 0.755
actn2 actinin, alpha 2 0.754
mfn2 mitofusin 2 0.750
sept6 septin 6 0.749
hspg2 heparan sulfate proteoglycan 2 0.746
mmp9 matrix metalloproteinase 9 0.745
sim1a single-minded homolog 1a (Drosophila) 0.744
notch2 notch homolog 2 0.742
ncam1b neural cell adhesion molecule 1b 0.730
atoh1a atonal homolog 1a 0.728
emx3 empty spiracles homeobox 3 0.728
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.727
lama5 laminin, alpha 5 0.723
dpysl3 dihydropyrimidinase-like 3 0.722
inab internexin neuronal intermediate filament protein, alpha b 0.720
pcdh10a protocadherin 10a 0.710
fgf10a fibroblast growth factor 10a 0.706
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.704
wnt1 wingless-type MMTV integration site family, member 1 0.702
gpr98 G protein-coupled receptor 98 0.700
foxa2 forkhead box A2 0.699
actn1 actinin, alpha 1 0.695
dlb deltaB 0.694
esrrga estrogen-related receptor gamma a 0.690
ptf1a pancreas specific transcription factor, 1a 0.690
nxph1 neurexophilin 1 0.687
mpp5a membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a) 0.681
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.999
hlh-2 Protein HLH-2 0.983
pha-4 Protein PHA-4 0.979
osm-5 Protein OSM-5 0.971
pry-1 Protein PRY-1 0.941
unc-73 Protein UNC-73 0.932
osm-3 Protein OSM-3 0.927
unc-53 Protein UNC-53 0.893
act-4 Protein ACT-4 0.891
elt-6 Protein ELT-6 0.890
nhr-67 Protein NHR-67 0.873
unc-52 Protein UNC-52 0.871
osm-6 Protein OSM-6 0.868
atn-1 Protein ATN-1 0.859
ida-1 Protein IDA-1 0.847
flt-1 Protein FLT-1 0.846
che-13 Protein CHE-13 0.841
egl-46 Protein EGL-46 0.826
hbl-1 Protein HBL-1 0.805
let-60 Protein LET-60 0.796
T27A3.1 Protein T27A3.1 0.794
bar-1 Protein BAR-1 0.779
unc-104 Protein UNC-104 0.764
sem-5 Protein SEM-5 0.756
fkh-2 Protein FKH-2 0.754
sli-1 Protein SLI-1 0.747
sel-12 Protein SEL-12 0.738
vab-3 Protein VAB-3 0.736
cye-1 Protein CYE-1 0.736
hmp-1 Protein HMP-1 0.727
che-2 Protein CHE-2 0.727
daf-11 Protein DAF-11 0.725
hnd-1 Protein HND-1 0.724
egl-13 Protein EGL-13 0.720
hlh-1 Protein HLH-1 0.712
unc-42 Protein UNC-42 0.676
cam-1 Protein CAM-1 0.673
ain-1 Protein AIN-1 0.612
mig-5 Protein MIG-5 0.606
ten-1 Protein TEN-1 0.600
lin-29 Protein LIN-29 0.597
jbts-14 Protein JBTS-14 0.581
ldb-1 Protein LDB-1 0.578
unc-9 Protein UNC-9 0.574
syg-1 Protein SYG-1 0.574
pop-1 Protein POP-1 0.569
egl-8 Protein EGL-8 0.549
mpk-1 Protein MPK-1 0.547
mec-8 Protein MEC-8 0.544
eor-1 Protein EOR-1 0.540
pat-3 Protein PAT-3 0.528
T28F4.1 Protein T28F4.1 0.523
nphp-4 Protein NPHP-4 0.523
sax-3 Protein SAX-3 0.515
cnd-1 Protein CND-1 0.507
aspm-1 Protein ASPM-1 0.506
egl-15 Protein EGL-15 0.501
lsy-2 Protein LSY-2 0.498
glp-1 Protein GLP-1 0.496
T21B6.3 Protein T21B6.3 0.491
tbc-2 Protein TBC-2 0.490
mep-1 Protein MEP-1 0.483
hcp-3 Protein HCP-3 0.481
mef-2 Protein MEF-2 0.472
K10D6.4 Protein K10D6.4 0.469
teg-4 Protein TEG-4 0.462
sma-6 Protein SMA-6 0.450
pxf-1 Protein PXF-1 0.449
CELE_F59A6.5 Protein F59A6.5 0.448
C11E4.6 Protein C11E4.6 0.447
unc-62 Protein UNC-62 0.441
eps-8 Protein EPS-8 0.431
unc-98 Protein UNC-98 0.427
etr-1 Protein ETR-1 0.427
srgp-1 Protein SRGP-1 0.423
egl-5 Protein EGL-5 0.418
ncl-1 Protein NCL-1 0.417
goa-1 Protein GOA-1 0.414
fem-2 Protein FEM-2 0.410
gon-4 Protein GON-4 0.403
tni-3 Protein TNI-3 0.400
nphp-1 Protein NPHP-1 0.398
daf-3 Protein DAF-3 0.397
soc-2 Protein SOC-2 0.396
egl-27 Protein EGL-27 0.386
daf-19 Protein DAF-19 0.381
arx-2 Protein ARX-2 0.381
osm-12 Protein OSM-12 0.381
elpc-4 Protein ELPC-4 0.379
rnr-1 Protein RNR-1 0.372
lag-1 Protein LAG-1 0.371
odr-3 Protein ODR-3 0.369
M01A10.1 Protein M01A10.1 0.362
mom-2 Protein MOM-2 0.362
sur-2 Protein SUR-2 0.361
tbx-9 Protein TBX-9 0.360
Y44E3A.6 Protein Y44E3A.6 0.357
ceh-13 Protein CEH-13 0.356
ztf-19 Protein ZTF-19 0.353
age-1 Protein AGE-1 0.348
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
FYN FYN oncogene related to SRC, FGR, YES 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.999
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.998
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.998
GRB2 growth factor receptor-bound protein 2 0.998
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.998
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.998
EGFR epidermal growth factor receptor 0.997
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.994
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.990
CREBBP CREB binding protein 0.989
ATXN1 ataxin 1 0.988
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.988
BCAR1 breast cancer anti-estrogen resistance 1 0.982
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.981
RHOA ras homolog gene family, member A 0.980
FLNA filamin A, alpha 0.978
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.973
FN1 fibronectin 1 0.970
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.952
LCK lymphocyte-specific protein tyrosine kinase 0.942
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.940
MOBKL3 MOB1, Mps One Binder kinase activator-like 3 (yeast) 0.937
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.936
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.935
ACTB actin, beta 0.932
PXN paxillin 0.927
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.925
QKI quaking homolog, KH domain RNA binding (mouse) 0.919
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.911
GAS7 growth arrest-specific 7 0.911
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.903
MSN moesin 0.896
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.893
SMAD2 SMAD family member 2 0.886
ATN1 atrophin 1 0.878
MAPT microtubule-associated protein tau 0.874
PLCG1 phospholipase C, gamma 1 0.870
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.863
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.856
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.853
LMNA lamin A/C 0.844
PPP1R12A protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.840
NCOR1 nuclear receptor corepressor 1 0.830
AR androgen receptor 0.828
ILK integrin-linked kinase 0.821
SYK spleen tyrosine kinase 0.815
CFL1 cofilin 1 (non-muscle) 0.814
FGFR1 fibroblast growth factor receptor 1 0.804
APP amyloid beta (A4) precursor protein 0.798
MET met proto-oncogene (hepatocyte growth factor receptor) 0.797
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.797
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.790
RAB1A RAB1A, member RAS oncogene family 0.788
ZYX zyxin 0.780
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.755
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.735
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.720
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.720
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.717
ABI1 abl-interactor 1 0.701
SMAD1 SMAD family member 1 0.695
SFN stratifin 0.690
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.687
ITSN1 intersectin 1 (SH3 domain protein) 0.686
RBBP4 retinoblastoma binding protein 4 0.673
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.667
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.663
MAPK8 mitogen-activated protein kinase 8 0.662
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.638
RB1 retinoblastoma 1 0.634
MPDZ multiple PDZ domain protein 0.631
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.625
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.623
TP53 tumor protein p53 0.620
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.617
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.617
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.612
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.611
GRB7 growth factor receptor-bound protein 7 0.608
JUN jun proto-oncogene 0.602
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.598
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.590
MPRIP myosin phosphatase Rho interacting protein 0.587
JAG1 jagged 1 0.587
RAB5A RAB5A, member RAS oncogene family 0.581
PRKCZ protein kinase C, zeta 0.578
ARRB1 arrestin, beta 1 0.578
SOS1 son of sevenless homolog 1 (Drosophila) 0.577
PKM2 pyruvate kinase, muscle 0.560
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.560
HSPG2 heparan sulfate proteoglycan 2 0.555
SMAD3 SMAD family member 3 0.554
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.550
NCK1 NCK adaptor protein 1 0.547
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.525
PTK2 PTK2 protein tyrosine kinase 2 0.524
WDYHV1 WDYHV motif containing 1 0.519
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.519
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 0.968
Lin7b lin-7 homolog b (C. elegans) 0.866
Map2 microtubule-associated protein 2 0.668
Actb actin, beta 0.658
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.613
Nrxn1 neurexin 1 0.601
Pls3 plastin 3 (T-isoform) 0.593
Ccl2 chemokine (C-C motif) ligand 2 0.579
Gria2 glutamate receptor, ionotropic, AMPA 2 0.569
Cttn cortactin 0.551
Strn striatin, calmodulin binding protein 0.550
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.549
Plau plasminogen activator, urokinase 0.549
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.547
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.545
Accn1 amiloride-sensitive cation channel 1, neuronal 0.522
Nrxn3 neurexin 3 0.516
Pfn1 profilin 1 0.510
Grip1 glutamate receptor interacting protein 1 0.506
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.494
Fyn FYN oncogene related to SRC, FGR, YES 0.487
Map1b microtubule-associated protein 1B 0.485
Bcl2 B-cell CLL/lymphoma 2 0.483
Prkca protein kinase C, alpha 0.477
Map6 microtubule-associated protein 6 0.475
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.467
Myo1c myosin IC 0.460
Anxa2 annexin A2 0.452
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.450
Jak1 Janus kinase 1 0.433
Cd9 CD9 molecule 0.430
Rap1b RAP1B, member of RAS oncogene family 0.424
App amyloid beta (A4) precursor protein 0.420
Drd2 dopamine receptor D2 0.417
Dchs1 dachsous 1 (Drosophila) 0.416
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.415
Dlg4 discs, large homolog 4 (Drosophila) 0.413
Sp4 Sp4 transcription factor 0.408
Cyth3 cytohesin 3 0.396
Ncam1 neural cell adhesion molecule 1 0.394
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.394
Sirpa signal-regulatory protein alpha 0.390
C1r complement component 1, r subcomponent 0.387
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.381
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.379
Syt4 synaptotagmin IV 0.372
Brunol4 bruno-like 4, RNA binding protein (Drosophila) 0.372
Tmod2 tropomodulin 2 0.370
Ednrb endothelin receptor type B 0.360
Gnal guanine nucleotide binding protein, alpha stimulating, olfactory type 0.359
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.355
Sncb synuclein, beta 0.354
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.352
Met met proto-oncogene 0.351
Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 0.350
Syt17 synaptotagmin XVII 0.348
Pde4b phosphodiesterase 4B, cAMP specific 0.347
Lamc1 laminin, gamma 1 0.345
Sdc3 syndecan 3 0.345
Nr4a2 nuclear receptor subfamily 4, group A, member 2 0.340
Itgb1 integrin, beta 1 0.340
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.338
Utrn utrophin 0.338
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.336
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.334
Sc65 synaptonemal complex protein SC65 0.333
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.332
Vcan versican 0.331
Acvr1 activin A receptor, type I 0.328
Hck hemopoietic cell kinase 0.318
Tacr3 tachykinin receptor 3 0.318
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.318
Stx1b syntaxin 1B 0.316
Ppp2r2c protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform 0.312
Galr3 galanin receptor 3 0.312
Tpm3 tropomyosin 3, gamma 0.311
Cd44 Cd44 molecule 0.311
Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.310
Gria3 glutamate receptor, ionotrophic, AMPA 3 0.308
Picalm phosphatidylinositol binding clathrin assembly protein 0.305
Spire1 spire homolog 1 (Drosophila) 0.302
Adam17 ADAM metallopeptidase domain 17 0.299
Socs3 suppressor of cytokine signaling 3 0.297
Nfib nuclear factor I/B 0.295
Adrb1 adrenergic, beta-1-, receptor 0.294
Gdf11 growth differentiation factor 11 0.294
Agtr2 angiotensin II receptor, type 2 0.291
Cadm1 cell adhesion molecule 1 0.287
Cltc clathrin, heavy chain (Hc) 0.285
Stat6 signal transducer and activator of transcription 6 0.284
Fgfr1 Fibroblast growth factor receptor 1 0.283
Hoxa2 homeo box A2 0.280
Bdkrb2 bradykinin receptor B2 0.279
Samd14 sterile alpha motif domain containing 14 0.278
Lnpep leucyl/cystinyl aminopeptidase 0.277
Sptan1 spectrin, alpha, non-erythrocytic 1 0.277
Iqgap1 IQ motif containing GTPase activating protein 1 0.274
Scn3a sodium channel, voltage-gated, type III, alpha 0.274
Slc6a1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 0.271
Ngf nerve growth factor (beta polypeptide) 0.271
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism