The network for 'tyrosine phosphorylation of stat protein' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

tyrosine phosphorylation of stat protein

The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

Danio rerio
Name Description Probability Func Analog Organism
il6st interleukin 6 signal transducer 0.879
socs3a suppressor of cytokine signaling 3a 0.773
her15.1 hairy and enhancer of split-related 15.1 0.691
il6r interleukin 6 receptor 0.614
cmyb transcription factor cmyb 0.351
s1pr2 sphingosine-1-phosphate receptor 2 0.293
prox1 prospero-related homeobox gene 1 0.216
il7r interleukin 7 receptor 0.215
stat3 signal transduction and activation of transcription 3 0.206
mmp9 matrix metalloproteinase 9 0.181
stm starmaker 0.176
kita kit receptor a 0.160
grn1 granulin 1 0.157
irf9 interferon regulatory factor 9 0.151
cacna1da calcium channel, voltage-dependent, L type, alpha 1D subunit, a 0.142
ccl25b chemokine (C-C motif) ligand 25b 0.139
scn1bb sodium channel, voltage-gated, type I, beta b 0.126
insm1a insulinoma-associated 1a 0.121
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.117
socs1 suppressor of cytokine signaling 1 0.113
zgc:63721 zgc:63721 0.106
junb jun B proto-oncogene 0.102
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.097
grn2 granulin 2 0.093
gadd45bb growth arrest and DNA-damage-inducible, beta b 0.090
atf3 activating transcription factor 3 0.086
ntrk3b neurotrophic tyrosine kinase, receptor, type 3b 0.085
iclp1 invariant chain-like protein 1 0.076
glcci1 glucocorticoid induced transcript 1 0.074
stat1b signal transducer and activator of transcription 1b 0.073
nr2f6b nuclear receptor subfamily 2, group F, member 6b 0.071
nos2a nitric oxide synthase 2a, inducible 0.071
tagln3b transgelin 3b 0.071
si:ch211-89f7.4 si:ch211-89f7.4 0.070
fos v-fos FBJ murine osteosarcoma viral oncogene homolog 0.069
ltk leukocyte tyrosine kinase 0.068
cited3 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 3 0.067
bmpr2b bone morphogenetic protein receptor, type II b (serine/threonine kinase) 0.066
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.064
sb:cb429 sb:cb429 0.061
socs3b suppressor of cytokine signaling 3b 0.060
hoxb5a homeo box B5a 0.057
sox19a SRY-box containing gene 19a 0.056
cbfb core-binding factor, beta subunit 0.056
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.056
tnfrsf18 tumor necrosis factor receptor superfamily, member 18 0.055
dlb deltaB 0.055
LOC100004261 mitogen-activated protein kinase kinase kinase 14-like 0.053
LOC553366 hypothetical protein LOC553366 0.052
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.052
dusp2 dual specificity phosphatase 2 0.052
her4.2 hairy-related 4.2 0.047
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.047
zgc:64051 zgc:64051 0.047
tlr3 toll-like receptor 3 0.047
fcer1gl Fc receptor, IgE, high affinity I, gamma polypeptide like 0.046
adcyap1r1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.046
ifi35 interferon-induced protein 35 0.045
gadd45g growth arrest and DNA-damage-inducible, gamma 0.044
capn2b calpain 2, (m/II) large subunit b 0.044
sox7 SRY-box containing gene 7 0.044
oprd1b opioid receptor, delta 1b 0.043
ahcyl1 S-adenosylhomocysteine hydrolase-like 1 0.043
ighz immunoglobulin heavy constant zeta 0.043
wnk1 WNK lysine deficient protein kinase 1 0.043
bmpr2a bone morphogenetic protein receptor, type II a (serine/threonine kinase) 0.042
ren renin 0.041
gadd45ba growth arrest and DNA-damage-inducible, beta a 0.041
LOC563363 cholesterol side-chain cleavage enzyme, mitochondrial-like 0.041
nrp2b neuropilin 2b 0.041
kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 0.041
LOC567405 novel protein similar to vertebrate megakaryocyte-associated tyrosine kinase (MATK) 0.041
hnf1bb HNF1 homeobox Bb 0.040
prom1b prominin 1 b 0.039
gtf2e2 general transcription factor IIE, polypeptide 2, beta 0.038
psme1 proteasome activator subunit 1 0.038
cpn1 carboxypeptidase N, polypeptide 1 0.038
dnm2 dynamin 2 0.038
abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.036
scrt2 scratch homolog 2, zinc finger protein (Drosophila) 0.036
zgc:153997 zgc:153997 0.036
gbp1 guanylate binding protein 1 0.036
idh1 isocitrate dehydrogenase 1 (NADP+), soluble 0.036
fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.035
irf7 interferon regulatory factor 7 0.035
nitr9 novel immune-type receptor 9 0.035
elovl4a elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a 0.035
taf3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto 0.034
scn1ba sodium channel, voltage-gated, type I, beta a 0.034
nr2f2 nuclear receptor subfamily 2, group F, member 2 0.033
tnfsf18 tumor necrosis factor (ligand) superfamily, member 18 0.033
pmela premelanosome protein a 0.033
epas1a endothelial PAS domain protein 1a 0.033
dbx1a developing brain homeobox 1a 0.032
sema6dl sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like 0.032
dla deltaA 0.032
pax7b paired box gene 7b 0.032
rtn1a reticulon 1a 0.032
sc:d812 sc:d812 0.032
bbs4 Bardet-Biedl syndrome 4 0.031
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
HLHmdelta E(spl) region transcript mdelta 0.985
HLHmgamma E(spl) region transcript mgamma 0.909
HLHm7 E(spl) region transcript m7 0.843
HLHm5 E(spl) region transcript m5 0.834
HLHmbeta E(spl) region transcript mbeta 0.638
malpha E(spl) region transcript malpha 0.624
E(spl) Enhancer of split 0.573
HLHm3 E(spl) region transcript m3 0.467
m2 E(spl) region transcript m2 0.415
m4 E(spl) region transcript m4 0.304
sc scute 0.167
ac achaete 0.124
Tom Twin of m4 0.120
BobA Brother of Bearded A 0.105
Dad Daughters against dpp 0.047
klar klarsicht 0.039
ci cubitus interruptus 0.032
Rel Relish 0.029
Pvf2 PDGF- and VEGF-related factor 2 0.028
tap target of Poxn 0.026
kuz kuzbanian 0.025
kay kayak 0.025
gcm glial cells missing 0.024
stumps CG31317 gene product from transcript CG31317-RC 0.023
repo reversed polarity 0.021
scb scab 0.020
noc no ocelli 0.017
shn schnurri 0.017
jim CG11352 gene product from transcript CG11352-RB 0.017
drpr draper 0.016
rhea CG6831 gene product from transcript CG6831-RA 0.015
kst karst 0.014
rols rolling pebbles 0.014
sec71 CG7578 gene product from transcript CG7578-RA 0.013
mbc myoblast city 0.013
klu klumpfuss 0.012
ush u-shaped 0.012
svr silver 0.012
vri vrille 0.012
cora coracle 0.012
ase asense 0.012
Lim3 CG10699 gene product from transcript CG10699-RB 0.011
ato atonal 0.011
CG3638 CG3638 gene product from transcript CG3638-RE 0.011
Oatp74D Organic anion transporting polypeptide 74D 0.011
bib big brain 0.011
Sara Smad anchor for receptor activation 0.011
srp serpent 0.011
Myo31DF Myosin 31DF 0.011
sima similar 0.011
h hairy 0.011
Krn Keren 0.010
CG13868 CG13868 gene product from transcript CG13868-RA 0.010
CG15365 CG15365 gene product from transcript CG15365-RA 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 1.000
EGFR epidermal growth factor receptor 0.998
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.997
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.997
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.996
SOCS3 suppressor of cytokine signaling 3 0.993
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.980
SYK spleen tyrosine kinase 0.973
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.959
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.959
JAK2 Janus kinase 2 0.927
GRB2 growth factor receptor-bound protein 2 0.925
CAV1 caveolin 1, caveolae protein, 22kDa 0.922
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.918
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.847
GRB7 growth factor receptor-bound protein 7 0.802
GHR growth hormone receptor 0.791
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.774
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.756
CCR5 chemokine (C-C motif) receptor 5 0.747
PLCG1 phospholipase C, gamma 1 0.739
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.736
CCL4 chemokine (C-C motif) ligand 4 0.669
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.664
EPOR erythropoietin receptor 0.639
ICAM1 intercellular adhesion molecule 1 0.637
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.632
PTPRB protein tyrosine phosphatase, receptor type, B 0.573
FYN FYN oncogene related to SRC, FGR, YES 0.566
CD44 CD44 molecule (Indian blood group) 0.546
FGF1 fibroblast growth factor 1 (acidic) 0.492
CCL2 chemokine (C-C motif) ligand 2 0.461
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.452
VEGFA vascular endothelial growth factor A 0.443
IL4R interleukin 4 receptor 0.420
EZR ezrin 0.404
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.387
FADD Fas (TNFRSF6)-associated via death domain 0.369
TRADD TNFRSF1A-associated via death domain 0.365
TRAF5 TNF receptor-associated factor 5 0.362
CXCL9 chemokine (C-X-C motif) ligand 9 0.334
MED28 mediator complex subunit 28 0.333
SPRR2A small proline-rich protein 2A 0.284
STAT4 signal transducer and activator of transcription 4 0.254
SOCS1 suppressor of cytokine signaling 1 0.250
IL23A interleukin 23, alpha subunit p19 0.245
IL6 interleukin 6 (interferon, beta 2) 0.244
IRS1 insulin receptor substrate 1 0.244
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.237
JAK1 Janus kinase 1 0.228
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.217
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.215
CSH2 chorionic somatomammotropin hormone 2 0.204
HDAC2 histone deacetylase 2 0.202
ZNF746 zinc finger protein 746 0.194
NRP1 neuropilin 1 0.186
GAB1 GRB2-associated binding protein 1 0.180
IL2RG interleukin 2 receptor, gamma 0.179
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.179
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.166
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.160
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.159
FGFR1 fibroblast growth factor receptor 1 0.157
VCAM1 vascular cell adhesion molecule 1 0.151
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.147
STAT1 signal transducer and activator of transcription 1, 91kDa 0.138
GH1 growth hormone 1 0.135
IL8 interleukin 8 0.133
ITGB1BP3 integrin beta 1 binding protein 3 0.132
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.124
CCL7 chemokine (C-C motif) ligand 7 0.117
FASLG Fas ligand (TNF superfamily, member 6) 0.114
IL1B interleukin 1, beta 0.112
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.111
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.110
PTEN phosphatase and tensin homolog 0.109
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.109
CXCL2 chemokine (C-X-C motif) ligand 2 0.109
CAV2 caveolin 2 0.107
GH2 growth hormone 2 0.105
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.105
SLA Src-like-adaptor 0.103
IL10 interleukin 10 0.101
CCL8 chemokine (C-C motif) ligand 8 0.101
CCL5 chemokine (C-C motif) ligand 5 0.100
TNF tumor necrosis factor 0.100
VAV3 vav 3 guanine nucleotide exchange factor 0.100
LCK lymphocyte-specific protein tyrosine kinase 0.100
CCR7 chemokine (C-C motif) receptor 7 0.098
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.098
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.098
NCK1 NCK adaptor protein 1 0.094
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.094
IFNG interferon, gamma 0.089
LIFR leukemia inhibitory factor receptor alpha 0.086
CD40 CD40 molecule, TNF receptor superfamily member 5 0.086
CXCL10 chemokine (C-X-C motif) ligand 10 0.085
IDE insulin-degrading enzyme 0.083
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.082
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Mus musculus
Name Description Probability Func Analog Organism
Lepr leptin receptor 0.998
Tnf tumor necrosis factor 0.993
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.959
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.956
Inpp5d inositol polyphosphate-5-phosphatase D 0.936
Esr1 estrogen receptor 1 (alpha) 0.921
Stat3 signal transducer and activator of transcription 3 0.914
Emx1 empty spiracles homolog 1 (Drosophila) 0.909
Lyz2 lysozyme 2 0.872
Igh immunoglobulin heavy chain complex 0.844
Emx2 empty spiracles homolog 2 (Drosophila) 0.791
Il10 interleukin 10 0.784
Ifng interferon gamma 0.773
Cd19 CD19 antigen 0.731
Csf1 colony stimulating factor 1 (macrophage) 0.703
Ikzf1 IKAROS family zinc finger 1 0.692
Col1a1 collagen, type I, alpha 1 0.647
Otx2 orthodenticle homolog 2 (Drosophila) 0.616
Btk Bruton agammaglobulinemia tyrosine kinase 0.574
Ptprc protein tyrosine phosphatase, receptor type, C 0.568
Lhx3 LIM homeobox protein 3 0.531
Fas Fas (TNF receptor superfamily member 6) 0.529
Rag1 recombination activating gene 1 0.499
Cbl Casitas B-lineage lymphoma 0.494
Il2rg interleukin 2 receptor, gamma chain 0.462
Il6 interleukin 6 0.457
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.452
Nos2 nitric oxide synthase 2, inducible 0.451
Stat5a signal transducer and activator of transcription 5A 0.433
Ret ret proto-oncogene 0.394
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.393
Il4 interleukin 4 0.362
Lck lymphocyte protein tyrosine kinase 0.346
Mmp9 matrix metallopeptidase 9 0.343
Tgfb1 transforming growth factor, beta 1 0.343
Ldlr low density lipoprotein receptor 0.335
Fgf8 fibroblast growth factor 8 0.323
Jak2 Janus kinase 2 0.286
Cav1 caveolin 1, caveolae protein 0.270
Prf1 perforin 1 (pore forming protein) 0.261
Hes5 hairy and enhancer of split 5 (Drosophila) 0.240
Sox2 SRY-box containing gene 2 0.236
Il6st interleukin 6 signal transducer 0.218
Tcra T-cell receptor alpha chain 0.217
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.207
Vegfa vascular endothelial growth factor A 0.207
Grb2 growth factor receptor bound protein 2 0.203
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.178
Isl1 ISL1 transcription factor, LIM/homeodomain 0.172
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.161
Nos3 nitric oxide synthase 3, endothelial cell 0.153
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.149
Was Wiskott-Aldrich syndrome homolog (human) 0.145
Fyb FYN binding protein 0.138
Foxp3 forkhead box P3 0.136
Chd7 chromodomain helicase DNA binding protein 7 0.133
Il1r1 interleukin 1 receptor, type I 0.126
Lif leukemia inhibitory factor 0.116
Nlrp3 NLR family, pyrin domain containing 3 0.115
Tlr4 toll-like receptor 4 0.109
Ghr growth hormone receptor 0.109
S1pr1 sphingosine-1-phosphate receptor 1 0.108
Foxn1 forkhead box N1 0.102
Itgb2 integrin beta 2 0.101
Plcg1 phospholipase C, gamma 1 0.098
Nrg1 neuregulin 1 0.096
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.096
Ccl2 chemokine (C-C motif) ligand 2 0.094
Src Rous sarcoma oncogene 0.093
Zeb1 zinc finger E-box binding homeobox 1 0.092
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.091
Cd40lg CD40 ligand 0.089
Pax6 paired box gene 6 0.087
Bdnf brain derived neurotrophic factor 0.084
Stat5b signal transducer and activator of transcription 5B 0.083
Cish cytokine inducible SH2-containing protein 0.082
Socs1 suppressor of cytokine signaling 1 0.082
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.074
Nsf N-ethylmaleimide sensitive fusion protein 0.071
Kit kit oncogene 0.070
Fcgr2b Fc receptor, IgG, low affinity IIb 0.070
Gdnf glial cell line derived neurotrophic factor 0.069
Dok1 docking protein 1 0.066
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.065
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.065
Phox2b paired-like homeobox 2b 0.062
Socs2 suppressor of cytokine signaling 2 0.060
Cd44 CD44 antigen 0.060
Nf1 neurofibromatosis 1 0.056
Nos1 nitric oxide synthase 1, neuronal 0.056
Fyn Fyn proto-oncogene 0.055
Pdx1 pancreatic and duodenal homeobox 1 0.054
Il12b interleukin 12b 0.054
Pparg peroxisome proliferator activated receptor gamma 0.053
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.053
Blnk B-cell linker 0.050
Ptk2 PTK2 protein tyrosine kinase 2 0.050
Epor erythropoietin receptor 0.048
Ptgs2 prostaglandin-endoperoxide synthase 2 0.047
Mefv Mediterranean fever 0.046
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism