IMP

Process View

Homo sapiens

4 genes annotated in human

Multi-species View

negative regulation of lymphocyte migration

GO:2000402

Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of lymphocyte migration"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of lymphocyte migration" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000
CCL4	chemokine (C-C motif) ligand 4	0.999	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.985
CCL2	chemokine (C-C motif) ligand 2	0.979
DPP4	dipeptidyl-peptidase 4	0.978
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.977	Human
IL8	interleukin 8	0.971
CXCL2	chemokine (C-X-C motif) ligand 2	0.965
IL1B	interleukin 1, beta	0.961
CCL8	chemokine (C-C motif) ligand 8	0.954	Human
CCL13	chemokine (C-C motif) ligand 13	0.921	Human
CCL5	chemokine (C-C motif) ligand 5	0.901	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.887
IDE	insulin-degrading enzyme	0.817
IL6	interleukin 6 (interferon, beta 2)	0.794
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.778
CCL22	chemokine (C-C motif) ligand 22	0.754	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.701
CCR7	chemokine (C-C motif) receptor 7	0.672
CXCL11	chemokine (C-X-C motif) ligand 11	0.665
RGS1	regulator of G-protein signaling 1	0.620
CCL3	chemokine (C-C motif) ligand 3	0.540	Human
CCL7	chemokine (C-C motif) ligand 7	0.524	Human
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.431
CCL19	chemokine (C-C motif) ligand 19	0.412	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.394
CCR4	chemokine (C-C motif) receptor 4	0.364
CCL11	chemokine (C-C motif) ligand 11	0.334	Human
DARC	Duffy blood group, chemokine receptor	0.334
IFNG	interferon, gamma	0.323
ICAM1	intercellular adhesion molecule 1	0.310
CD83	CD83 molecule	0.308
CXCL5	chemokine (C-X-C motif) ligand 5	0.302
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.285
IL10	interleukin 10	0.276
CCR1	chemokine (C-C motif) receptor 1	0.261
CCL20	chemokine (C-C motif) ligand 20	0.239	Human
VCAM1	vascular cell adhesion molecule 1	0.207
UBD	ubiquitin D	0.206
IL2RB	interleukin 2 receptor, beta	0.198
SELE	selectin E	0.194
IL7R	interleukin 7 receptor	0.191
BCL2A1	BCL2-related protein A1	0.166
IL1RN	interleukin 1 receptor antagonist	0.166
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.157
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.153
CH25H	cholesterol 25-hydroxylase	0.135
FPR3	formyl peptide receptor 3	0.129
TNF	tumor necrosis factor	0.125
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.111
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.101
LAMP3	lysosomal-associated membrane protein 3	0.099
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.097
CCL21	chemokine (C-C motif) ligand 21	0.096
TRAF1	TNF receptor-associated factor 1	0.090
IL2RG	interleukin 2 receptor, gamma	0.087
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.082
CXCR6	chemokine (C-X-C motif) receptor 6	0.080
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.078
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.077
ADAMDEC1	ADAM-like, decysin 1	0.075
SLAMF8	SLAM family member 8	0.070
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.062
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.060
CCR3	chemokine (C-C motif) receptor 3	0.058
IL1R2	interleukin 1 receptor, type II	0.056
EBI3	Epstein-Barr virus induced 3	0.055
CCL17	chemokine (C-C motif) ligand 17	0.051	Human
IL1A	interleukin 1, alpha	0.048
AQP9	aquaporin 9	0.046
INHBA	inhibin, beta A	0.044
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.044
IDO1	indoleamine 2,3-dioxygenase 1	0.043
ARRB1	arrestin, beta 1	0.043
XCL2	chemokine (C motif) ligand 2	0.041	Human
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.041
XCL1	chemokine (C motif) ligand 1	0.038	Human
PI3	peptidase inhibitor 3, skin-derived	0.037
SLAMF7	SLAM family member 7	0.037
CD40	CD40 molecule, TNF receptor superfamily member 5	0.036
CCBP2	chemokine binding protein 2	0.036
CD69	CD69 molecule	0.036
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.034
STAT4	signal transducer and activator of transcription 4	0.032
MSC	musculin	0.030
IL18RAP	interleukin 18 receptor accessory protein	0.029
IL10RA	interleukin 10 receptor, alpha	0.028
CCL23	chemokine (C-C motif) ligand 23	0.028	Human
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.028
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.027
IL32	interleukin 32	0.027
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.027
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.027
CXCR3	chemokine (C-X-C motif) receptor 3	0.026
IL2RA	interleukin 2 receptor, alpha	0.025
BATF	basic leucine zipper transcription factor, ATF-like	0.025
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.025
C1QA	complement component 1, q subcomponent, A chain	0.025
OSMR	oncostatin M receptor	0.024
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.024
CHIT1	chitinase 1 (chitotriosidase)	0.024
BIRC3	baculoviral IAP repeat containing 3	0.024
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.023
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.023
LRRC32	leucine rich repeat containing 32	0.023
PDPN	podoplanin	0.021
CCL1	chemokine (C-C motif) ligand 1	0.021	Human
CSF1	colony stimulating factor 1 (macrophage)	0.021
IL21R	interleukin 21 receptor	0.021
CCRL2	chemokine (C-C motif) receptor-like 2	0.020
C2	complement component 2	0.020
TM7SF4	transmembrane 7 superfamily member 4	0.020
NNMT	nicotinamide N-methyltransferase	0.019
C1QB	complement component 1, q subcomponent, B chain	0.019
RGS16	regulator of G-protein signaling 16	0.019
CD209	CD209 molecule	0.019
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.019
CD1B	CD1b molecule	0.018
MMP19	matrix metallopeptidase 19	0.018
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.018
APOC1	apolipoprotein C-I	0.018
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.018
GNLY	granulysin	0.018
IL1F5	interleukin 1 family, member 5 (delta)	0.017
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.017
IL11	interleukin 11	0.017
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.017
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.017
IL13	interleukin 13	0.017
IRF4	interferon regulatory factor 4	0.016
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.016
PLAU	plasminogen activator, urokinase	0.016
SOD3	superoxide dismutase 3, extracellular	0.016
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.015
IL18R1	interleukin 18 receptor 1	0.015
GPR109B	G protein-coupled receptor 109B	0.015
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.014
PLEK	pleckstrin	0.014
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.014
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.014
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.014
PLAUR	plasminogen activator, urokinase receptor	0.014
CX3CL1	chemokine (C-X3-C motif) ligand 1	0.014
SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.014
C5AR1	complement component 5a receptor 1	0.014
CLEC5A	C-type lectin domain family 5, member A	0.013
IER3	immediate early response 3	0.013
CD80	CD80 molecule	0.013
ICOS	inducible T-cell co-stimulator	0.013
CD163	CD163 molecule	0.013
C3AR1	complement component 3a receptor 1	0.013
SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.013
CD40LG	CD40 ligand	0.013
TREM1	triggering receptor expressed on myeloid cells 1	0.013
SLAMF1	signaling lymphocytic activation molecule family member 1	0.012
TNIP3	TNFAIP3 interacting protein 3	0.012
CRMP1	collapsin response mediator protein 1	0.012
BDKRB1	bradykinin receptor B1	0.012
MSR1	macrophage scavenger receptor 1	0.012
PTGDS	prostaglandin D2 synthase 21kDa (brain)	0.012
CD160	CD160 molecule	0.011
C1QC	complement component 1, q subcomponent, C chain	0.011
DPT	dermatopontin	0.011
TPSB2	tryptase beta 2 (gene/pseudogene)	0.011
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.011
PTX3	pentraxin 3, long	0.011
TARP	TCR gamma alternate reading frame protein	0.011
ZC3H12A	zinc finger CCCH-type containing 12A	0.011
NLRP3	NLR family, pyrin domain containing 3	0.011
G0S2	G0/G1switch 2	0.011
SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	0.011
PRDM1	PR domain containing 1, with ZNF domain	0.011
SCARF1	scavenger receptor class F, member 1	0.011
S100A7	S100 calcium binding protein A7	0.011
TNFSF9	tumor necrosis factor (ligand) superfamily, member 9	0.011
EGR2	early growth response 2	0.011
KIR3DL1	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	0.010
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.010
GZMK	granzyme K (granzyme 3; tryptase II)	0.010
GPR171	G protein-coupled receptor 171	0.010
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.010
IL3RA	interleukin 3 receptor, alpha (low affinity)	0.010
CASQ2	calsequestrin 2 (cardiac muscle)	0.010
PTGES	prostaglandin E synthase	0.010