IMP

Process View

Homo sapiens

1 genes annotated in human

regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter

Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter" (in gray)

Name	Description	Probability	Func Analog Organism
CREBBP	CREB binding protein	1.000
NCOA1	nuclear receptor coactivator 1	1.000
NCOR2	nuclear receptor corepressor 2	1.000
EP300	E1A binding protein p300	1.000
RXRA	retinoid X receptor, alpha	1.000
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.998
NCOR1	nuclear receptor corepressor 1	0.998
RARA	retinoic acid receptor, alpha	0.997
NCOA6	nuclear receptor coactivator 6	0.996
TP53	tumor protein p53	0.984
ESR1	estrogen receptor 1	0.968
RUNX1	runt-related transcription factor 1	0.964
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.892
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.892
SIRT1	sirtuin 1	0.888
NCOA3	nuclear receptor coactivator 3	0.867
TRRAP	transformation/transcription domain-associated protein	0.817
HNF4A	hepatocyte nuclear factor 4, alpha	0.794
HIPK2	homeodomain interacting protein kinase 2	0.792
AR	androgen receptor	0.761
MED25	mediator complex subunit 25	0.756
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.663
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.661
ATXN7	ataxin 7	0.543
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.470
HR	hairless homolog (mouse)	0.457
SP1	Sp1 transcription factor	0.413
HTT	huntingtin	0.393
RB1	retinoblastoma 1	0.379
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.338
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.333
FOXO3	forkhead box O3	0.301
NCOA2	nuclear receptor coactivator 2	0.281
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.270
CREB1	cAMP responsive element binding protein 1	0.220
HDAC3	histone deacetylase 3	0.212
E2F1	E2F transcription factor 1	0.182
CUX1	cut-like homeobox 1	0.174
RBBP5	retinoblastoma binding protein 5	0.171
SKIL	SKI-like oncogene	0.165
USP22	ubiquitin specific peptidase 22	0.155
CHD9	chromodomain helicase DNA binding protein 9	0.142
PGR	progesterone receptor	0.140
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.135
SMAD2	SMAD family member 2	0.117
FOXO1	forkhead box O1	0.109
AHR	aryl hydrocarbon receptor	0.082
TADA2A	transcriptional adaptor 2A	0.081
ESRRG	estrogen-related receptor gamma	0.080
IRF2	interferon regulatory factor 2	0.079
PML	promyelocytic leukemia	0.072
PPARG	peroxisome proliferator-activated receptor gamma	0.071	Human
BCL6	B-cell CLL/lymphoma 6	0.068
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.067
CDK6	cyclin-dependent kinase 6	0.059
HDAC1	histone deacetylase 1	0.052
SETD1A	SET domain containing 1A	0.048
MYST1	MYST histone acetyltransferase 1	0.048
SETD7	SET domain containing (lysine methyltransferase) 7	0.046
SREBF2	sterol regulatory element binding transcription factor 2	0.044
PASK	PAS domain containing serine/threonine kinase	0.043
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.036
MEN1	multiple endocrine neoplasia I	0.036
ACACA	acetyl-CoA carboxylase alpha	0.034
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.033
CCND1	cyclin D1	0.032
HCFC1	host cell factor C1 (VP16-accessory protein)	0.032
TADA3	transcriptional adaptor 3	0.031
CCND3	cyclin D3	0.031
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.029
SATB1	SATB homeobox 1	0.028
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.027
HDAC4	histone deacetylase 4	0.027
KLF13	Kruppel-like factor 13	0.027
USF1	upstream transcription factor 1	0.027
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.025
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.025
SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	0.025
CXXC1	CXXC finger protein 1	0.024
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.024
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.024
ATXN1L	ataxin 1-like	0.024
SMAD3	SMAD family member 3	0.024
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.023
TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	0.021
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.020
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.020
PURA	purine-rich element binding protein A	0.020
SRCAP	Snf2-related CREBBP activator protein	0.019
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.019
E2F2	E2F transcription factor 2	0.018
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.018
CHD8	chromodomain helicase DNA binding protein 8	0.017
DAXX	death-domain associated protein	0.017
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.016
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.016
C16orf53	chromosome 16 open reading frame 53	0.016
E2F4	E2F transcription factor 4, p107/p130-binding	0.015
HDAC7	histone deacetylase 7	0.015
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.015
IRF3	interferon regulatory factor 3	0.015
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.015
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.015
SREBF1	sterol regulatory element binding transcription factor 1	0.014
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.014
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.014
CDK2	cyclin-dependent kinase 2	0.014
PYGO2	pygopus homolog 2 (Drosophila)	0.014
HDAC10	histone deacetylase 10	0.014
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.013
TAL1	T-cell acute lymphocytic leukemia 1	0.013
TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	0.013
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.012
ARNT	aryl hydrocarbon receptor nuclear translocator	0.012
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.012
FRK	fyn-related kinase	0.012
HDAC5	histone deacetylase 5	0.012
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.012
JUN	jun proto-oncogene	0.012
TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	0.011
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.011
MAPK14	mitogen-activated protein kinase 14	0.011
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.011
HCFC2	host cell factor C2	0.011
PRKD2	protein kinase D2	0.011
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.010
KIAA1267	KIAA1267	0.010
NCOA4	nuclear receptor coactivator 4	0.010