IMP

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Homo sapiens

2 genes annotated in human

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regulation of thyroid hormone generation

GO:2000609

Any process that modulates the frequency, rate or extent of thyroid hormone generation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of thyroid hormone generation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of thyroid hormone generation" (in gray)

Name	Description	Probability	Func Analog Organism
TAL1	T-cell acute lymphocytic leukemia 1	1.000
MEOX1	mesenchyme homeobox 1	1.000
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	1.000
NKX2-1	NK2 homeobox 1	1.000
RUNX1	runt-related transcription factor 1	0.988
TBX5	T-box 5	0.988
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.987
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.903
KLF13	Kruppel-like factor 13	0.886
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.726	Human
BBS1	Bardet-Biedl syndrome 1	0.701
GATA2	GATA binding protein 2	0.635	Human
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.535
ZFPM1	zinc finger protein, multitype 1	0.504
KLF1	Kruppel-like factor 1 (erythroid)	0.431
GATA4	GATA binding protein 4	0.427	Human
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.424
WNT7A	wingless-type MMTV integration site family, member 7A	0.334
WT1	Wilms tumor 1	0.325
PAX7	paired box 7	0.311
LMO2	LIM domain only 2 (rhombotin-like 1)	0.235
HNF1B	HNF1 homeobox B	0.197
LHX1	LIM homeobox 1	0.192
DAXX	death-domain associated protein	0.189
ZBTB16	zinc finger and BTB domain containing 16	0.178
COL2A1	collagen, type II, alpha 1	0.170
ALX4	ALX homeobox 4	0.161
SIM2	single-minded homolog 2 (Drosophila)	0.149
SFRP5	secreted frizzled-related protein 5	0.144
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.137
CLCNKB	chloride channel Kb	0.124
ALX3	ALX homeobox 3	0.123
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.113
PAX3	paired box 3	0.109
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.106
HNF1A	HNF1 homeobox A	0.102
GATA5	GATA binding protein 5	0.096	Human
HOXA11	homeobox A11	0.096
BBS2	Bardet-Biedl syndrome 2	0.096
MYOD1	myogenic differentiation 1	0.087
FOXN4	forkhead box N4	0.083
GLP1R	glucagon-like peptide 1 receptor	0.081
GP1BA	glycoprotein Ib (platelet), alpha polypeptide	0.078
BHLHE23	basic helix-loop-helix family, member e23	0.077
BBS4	Bardet-Biedl syndrome 4	0.072
PYY	peptide YY	0.072
ANK1	ankyrin 1, erythrocytic	0.071
SP1	Sp1 transcription factor	0.069
KLHL35	kelch-like 35 (Drosophila)	0.068
CRHR1	corticotropin releasing hormone receptor 1	0.067
HOXD9	homeobox D9	0.066
LTK	leukocyte receptor tyrosine kinase	0.064
PAX2	paired box 2	0.064	Human
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.059
LBX1	ladybird homeobox 1	0.055
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.054
TBX1	T-box 1	0.053
HOXB13	homeobox B13	0.052
NKX3-2	NK3 homeobox 2	0.051
EMX1	empty spiracles homeobox 1	0.051
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.050
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.049
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.048
HES2	hairy and enhancer of split 2 (Drosophila)	0.047
TLX1	T-cell leukemia homeobox 1	0.047
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.046
HOXB9	homeobox B9	0.046
PAX5	paired box 5	0.044	Human
CDX2	caudal type homeobox 2	0.043
HOXC5	homeobox C5	0.042
HDGFL1	hepatoma derived growth factor-like 1	0.040
TBX21	T-box 21	0.040
NKX2-8	NK2 homeobox 8	0.038
MESP1	mesoderm posterior 1 homolog (mouse)	0.037
HOXC11	homeobox C11	0.036
ALAS2	aminolevulinate, delta-, synthase 2	0.036
DHH	desert hedgehog	0.036
ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	0.035
SLC5A5	solute carrier family 5 (sodium iodide symporter), member 5	0.035
CALCA	calcitonin-related polypeptide alpha	0.035
OTP	orthopedia homeobox	0.035
RHAG	Rh-associated glycoprotein	0.034
FGF4	fibroblast growth factor 4	0.033
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.033
NKX3-1	NK3 homeobox 1	0.032
LYL1	lymphoblastic leukemia derived sequence 1	0.032
AMHR2	anti-Mullerian hormone receptor, type II	0.030
HOXD1	homeobox D1	0.030
BNC1	basonuclin 1	0.029
PNMT	phenylethanolamine N-methyltransferase	0.028
HOXD12	homeobox D12	0.028
APC2	adenomatosis polyposis coli 2	0.028
POU4F1	POU class 4 homeobox 1	0.028
LMX1B	LIM homeobox transcription factor 1, beta	0.028
FGF3	fibroblast growth factor 3	0.028
T	T, brachyury homolog (mouse)	0.027
FOXL2	forkhead box L2	0.027
HAND1	heart and neural crest derivatives expressed 1	0.027
EVX1	even-skipped homeobox 1	0.026
MEOX2	mesenchyme homeobox 2	0.026
HBE1	hemoglobin, epsilon 1	0.026
TP73	tumor protein p73	0.025
HOXC12	homeobox C12	0.025
HOXD13	homeobox D13	0.025
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.024
FEV	FEV (ETS oncogene family)	0.024
PF4	platelet factor 4	0.024
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.023
EFNA2	ephrin-A2	0.022
KRT37	keratin 37	0.022
SPTB	spectrin, beta, erythrocytic	0.022
GDNF	glial cell derived neurotrophic factor	0.022
MSX1	msh homeobox 1	0.022
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.021
PTH2	parathyroid hormone 2	0.021
NCR2	natural cytotoxicity triggering receptor 2	0.021
HIC1	hypermethylated in cancer 1	0.021
TCL1B	T-cell leukemia/lymphoma 1B	0.021
DRD4	dopamine receptor D4	0.020
HOXB5	homeobox B5	0.020
FOXE3	forkhead box E3	0.020
INHBB	inhibin, beta B	0.020
IRF4	interferon regulatory factor 4	0.020
GP9	glycoprotein IX (platelet)	0.019
GSX2	GS homeobox 2	0.019
TBXA2R	thromboxane A2 receptor	0.019
KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.019
CTSE	cathepsin E	0.019
SIX2	SIX homeobox 2	0.018
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.018
HOXD11	homeobox D11	0.018
SOX17	SRY (sex determining region Y)-box 17	0.018
CALCR	calcitonin receptor	0.018
HOXA4	homeobox A4	0.018
COL13A1	collagen, type XIII, alpha 1	0.018
WNT10A	wingless-type MMTV integration site family, member 10A	0.017
CXCR5	chemokine (C-X-C motif) receptor 5	0.017
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.017
CHRD	chordin	0.017
ALOX12	arachidonate 12-lipoxygenase	0.017
CDH16	cadherin 16, KSP-cadherin	0.017
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.016
SLC22A6	solute carrier family 22 (organic anion transporter), member 6	0.016
TLX2	T-cell leukemia homeobox 2	0.016
BARHL1	BarH-like homeobox 1	0.016
MPL	myeloproliferative leukemia virus oncogene	0.016
VAX2	ventral anterior homeobox 2	0.016
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.015
TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	0.015
EPX	eosinophil peroxidase	0.015
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.014
FOXD2	forkhead box D2	0.014
JPH3	junctophilin 3	0.014
HBQ1	hemoglobin, theta 1	0.014
SHH	sonic hedgehog	0.014
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.014
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.014
DLK1	delta-like 1 homolog (Drosophila)	0.014
HOXB8	homeobox B8	0.014
INSL3	insulin-like 3 (Leydig cell)	0.014
GFI1B	growth factor independent 1B transcription repressor	0.014
AMN	amnionless homolog (mouse)	0.013
PRDM12	PR domain containing 12	0.013
GJA4	gap junction protein, alpha 4, 37kDa	0.013
KRT13	keratin 13	0.013
POU3F1	POU class 3 homeobox 1	0.013
IGHMBP2	immunoglobulin mu binding protein 2	0.013
NPAS1	neuronal PAS domain protein 1	0.013
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.013
HOXB3	homeobox B3	0.012
C2orf55	chromosome 2 open reading frame 55	0.012
GALR3	galanin receptor 3	0.012
TSPAN32	tetraspanin 32	0.012
B4GALNT2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.012
FOXH1	forkhead box H1	0.012
FLT4	fms-related tyrosine kinase 4	0.012
ESPN	espin	0.012
ADARB2	adenosine deaminase, RNA-specific, B2	0.012
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.012
POU2F3	POU class 2 homeobox 3	0.012
ONECUT2	one cut homeobox 2	0.012
VTN	vitronectin	0.012
KEL	Kell blood group, metallo-endopeptidase	0.011
KAZALD1	Kazal-type serine peptidase inhibitor domain 1	0.011
EPHA8	EPH receptor A8	0.011
FOXA2	forkhead box A2	0.011
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.011
HOXB6	homeobox B6	0.011
PAEP	progestagen-associated endometrial protein	0.011
TFR2	transferrin receptor 2	0.011
PDX1	pancreatic and duodenal homeobox 1	0.011
AMBP	alpha-1-microglobulin/bikunin precursor	0.011
LHX2	LIM homeobox 2	0.011
NFE2	nuclear factor (erythroid-derived 2), 45kDa	0.011
MPO	myeloperoxidase	0.011
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.011
WNT1	wingless-type MMTV integration site family, member 1	0.011
PRPH	peripherin	0.011
SIX3	SIX homeobox 3	0.010
SMAD1	SMAD family member 1	0.010
KCNK4	potassium channel, subfamily K, member 4	0.010
LINGO3	leucine rich repeat and Ig domain containing 3	0.010
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.010
DLX2	distal-less homeobox 2	0.010