IMP

Process View

Homo sapiens

33 genes annotated in human

charcot marie tooth disease

DOID:10595

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "charcot marie tooth disease"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "charcot marie tooth disease" (in gray)

Name	Description	Probability	Func Analog Organism
BAG3	BCL2-associated athanogene 3	0.914
HSPB8	heat shock 22kDa protein 8	0.815
HSPB1	heat shock 27kDa protein 1	0.806
MARS	methionyl-tRNA synthetase	0.776
IARS	isoleucyl-tRNA synthetase	0.770
CRYAB	crystallin, alpha B	0.663	Human
DNM1	dynamin 1	0.465	Human
HSPB2	heat shock 27kDa protein 2	0.441	Human
SARS	seryl-tRNA synthetase	0.266
ASNS	asparagine synthetase (glutamine-hydrolyzing)	0.262
HSF1	heat shock transcription factor 1	0.262
EGR3	early growth response 3	0.228	Human
CARS	cysteinyl-tRNA synthetase	0.199
HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)	0.180
CLASP1	cytoplasmic linker associated protein 1	0.177
NCOA1	nuclear receptor coactivator 1	0.161
MARCH5	membrane-associated ring finger (C3HC4) 5	0.159
HSPA1B	heat shock 70kDa protein 1B	0.126
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.105
EGR1	early growth response 1	0.097	Human
RARA	retinoic acid receptor, alpha	0.094
RXRA	retinoid X receptor, alpha	0.090
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.080
KLC1	kinesin light chain 1	0.074
TSG101	tumor susceptibility gene 101	0.055
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.051
CTTN	cortactin	0.051
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.048
AARS	alanyl-tRNA synthetase	0.048
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.034
DNM2	dynamin 2	0.033
LDHA	lactate dehydrogenase A	0.030
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.029
BHLHE40	basic helix-loop-helix family, member e40	0.029
PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	0.028
SQSTM1	sequestosome 1	0.028
YARS	tyrosyl-tRNA synthetase	0.026
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	0.025
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.025
S100A10	S100 calcium binding protein A10	0.024
SF3B3	splicing factor 3b, subunit 3, 130kDa	0.023
ACP5	acid phosphatase 5, tartrate resistant	0.023
MGAT4B	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B	0.022
PLEC	plectin	0.021
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.021
FLNB	filamin B, beta	0.021
SREBF1	sterol regulatory element binding transcription factor 1	0.021
NINL	ninein-like	0.020
TARS	threonyl-tRNA synthetase	0.019
EIF1B	eukaryotic translation initiation factor 1B	0.019
SH3BP4	SH3-domain binding protein 4	0.018
FAM46A	family with sequence similarity 46, member A	0.018
SH3GL1	SH3-domain GRB2-like 1	0.018
FLNA	filamin A, alpha	0.018
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.017
IK	IK cytokine, down-regulator of HLA II	0.017
CD151	CD151 molecule (Raph blood group)	0.017
WASL	Wiskott-Aldrich syndrome-like	0.017
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.016
GARS	glycyl-tRNA synthetase	0.016
PSEN2	presenilin 2 (Alzheimer disease 4)	0.016
G6PD	glucose-6-phosphate dehydrogenase	0.015
TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)	0.015
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.014
SH3BP2	SH3-domain binding protein 2	0.014
RAB5A	RAB5A, member RAS oncogene family	0.014
VAC14	Vac14 homolog (S. cerevisiae)	0.014
TRIB3	tribbles homolog 3 (Drosophila)	0.014
SH3KBP1	SH3-domain kinase binding protein 1	0.014
FASN	fatty acid synthase	0.014
NONO	non-POU domain containing, octamer-binding	0.014
HSPB6	heat shock protein, alpha-crystallin-related, B6	0.013	Human
ITGB4	integrin, beta 4	0.013
PDCD6IP	programmed cell death 6 interacting protein	0.013
MAP4	microtubule-associated protein 4	0.013
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.013
PSAT1	phosphoserine aminotransferase 1	0.013
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.013
TYK2	tyrosine kinase 2	0.013
PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	0.013
PIAS4	protein inhibitor of activated STAT, 4	0.012
ALOX12	arachidonate 12-lipoxygenase	0.012
TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)	0.012
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.012
MED16	mediator complex subunit 16	0.011
RASAL2	RAS protein activator like 2	0.011
HIST2H3C	histone cluster 2, H3c	0.011
C16orf80	chromosome 16 open reading frame 80	0.011
CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	0.011
MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	0.011
RNF115	ring finger protein 115	0.011
TRIM74	tripartite motif containing 74	0.011
KIF1C	kinesin family member 1C	0.011	Human
TUBB6	tubulin, beta 6	0.011
BLMH	bleomycin hydrolase	0.011
WARS	tryptophanyl-tRNA synthetase	0.011
SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.011
HUWE1	HECT, UBA and WWE domain containing 1	0.011
AHNAK	AHNAK nucleoprotein	0.011	Human
RAB7A	RAB7A, member RAS oncogene family	0.011
PHGDH	phosphoglycerate dehydrogenase	0.011
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.011
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.011
UBA1	ubiquitin-like modifier activating enzyme 1	0.010
MYO1E	myosin IE	0.010
EPRS	glutamyl-prolyl-tRNA synthetase	0.010
PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	0.010
CRYAA	crystallin, alpha A	0.010	Human
ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.010
MED26	mediator complex subunit 26	0.010
TMBIM1	transmembrane BAX inhibitor motif containing 1	0.010
FGD4	FYVE, RhoGEF and PH domain containing 4	0.006
FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	0.005
GDAP1	ganglioside-induced differentiation-associated protein 1	0.005
KIF1B	kinesin family member 1B	0.005
TRPV4	transient receptor potential cation channel, subfamily V, member 4	0.005
MFN2	mitofusin 2	0.005
MPZ	myelin protein zero	0.004
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	0.004
PMP22	peripheral myelin protein 22	0.004
GJB1	gap junction protein, beta 1, 32kDa	0.004
GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.004
LITAF	lipopolysaccharide-induced TNF factor	0.004
PRX	periaxin	0.004
NEFL	neurofilament, light polypeptide	0.004
PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	0.004
NDRG1	N-myc downstream regulated 1	0.004
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.004
SBF2	SET binding factor 2	0.004
INF2	inverted formin, FH2 and WH2 domain containing	0.004
MED25	mediator complex subunit 25	0.004
EGR2	early growth response 2	0.003
SH3TC2	SH3 domain and tetratricopeptide repeats 2	0.003
AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1	0.002
LMNA	lamin A/C	0.002
MTMR2	myotubularin related protein 2	0.002
PRPS1	phosphoribosyl pyrophosphate synthetase 1	0.002