IMP

Process View

Homo sapiens

18 genes annotated in human

negative regulation of lipid transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of lipid transport"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of lipid transport" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.998
TLN1	talin 1	0.938
ALB	albumin	0.783
FN1	fibronectin 1	0.762
HP	haptoglobin	0.643
INSR	insulin receptor	0.620
GRB10	growth factor receptor-bound protein 10	0.590
ENG	endoglin	0.586
FHL2	four and a half LIM domains 2	0.511
APOA1	apolipoprotein A-I	0.411	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.349
TGFB1	transforming growth factor, beta 1	0.259
GAB1	GRB2-associated binding protein 1	0.256
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.229
ITGB4	integrin, beta 4	0.221
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.211
PXN	paxillin	0.209
APOC1	apolipoprotein C-I	0.181
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.160
APOE	apolipoprotein E	0.153
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.139
RARA	retinoic acid receptor, alpha	0.121
IGF1R	insulin-like growth factor 1 receptor	0.119
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.117
MAPT	microtubule-associated protein tau	0.116
A2M	alpha-2-macroglobulin	0.114
IRS1	insulin receptor substrate 1	0.094	Human
NCF1	neutrophil cytosolic factor 1	0.086
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.085
APOA2	apolipoprotein A-II	0.084
FLNA	filamin A, alpha	0.082
MED15	mediator complex subunit 15	0.082
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.078
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.075
LCAT	lecithin-cholesterol acyltransferase	0.067
PDIA3	protein disulfide isomerase family A, member 3	0.067
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.062
CTGF	connective tissue growth factor	0.062
APOC3	apolipoprotein C-III	0.062
THBS1	thrombospondin 1	0.060
GAB2	GRB2-associated binding protein 2	0.058
CD63	CD63 molecule	0.056
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.050
FOXO1	forkhead box O1	0.043
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.043
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.043
FRS2	fibroblast growth factor receptor substrate 2	0.043
MED25	mediator complex subunit 25	0.042
RXRA	retinoid X receptor, alpha	0.040
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.038
PELI3	pellino homolog 3 (Drosophila)	0.035
PRKCB	protein kinase C, beta	0.035
HNF4A	hepatocyte nuclear factor 4, alpha	0.035
CCDC115	coiled-coil domain containing 115	0.033
DTX1	deltex homolog 1 (Drosophila)	0.033
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.033
APOB	apolipoprotein B (including Ag(x) antigen)	0.031
CDCP1	CUB domain containing protein 1	0.030
APOC2	apolipoprotein C-II	0.029
TTR	transthyretin	0.029
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.028
PRKCZ	protein kinase C, zeta	0.026	Human
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.026
PLEC	plectin	0.025
PDPK1	3-phosphoinositide dependent protein kinase-1	0.025
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.024
PRKCA	protein kinase C, alpha	0.022
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.021	Human
LDLR	low density lipoprotein receptor	0.021
CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.020
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.020
TSC22D1	TSC22 domain family, member 1	0.020
ITGA6	integrin, alpha 6	0.019	Human
ITGB5	integrin, beta 5	0.019
FOXO3	forkhead box O3	0.019
PALLD	palladin, cytoskeletal associated protein	0.018
SH3RF1	SH3 domain containing ring finger 1	0.018
CYBA	cytochrome b-245, alpha polypeptide	0.017
CARD11	caspase recruitment domain family, member 11	0.016
PICK1	protein interacting with PRKCA 1	0.016
IRAK4	interleukin-1 receptor-associated kinase 4	0.016
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.016
IRS2	insulin receptor substrate 2	0.015
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.015
TRIM9	tripartite motif containing 9	0.014
BAD	BCL2-associated agonist of cell death	0.014
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.014	Human
CD9	CD9 molecule	0.014
CAV1	caveolin 1, caveolae protein, 22kDa	0.014
COL1A1	collagen, type I, alpha 1	0.014
MPZL1	myelin protein zero-like 1	0.014
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.013
PECAM1	platelet/endothelial cell adhesion molecule	0.013
IRAK3	interleukin-1 receptor-associated kinase 3	0.012
NCOA1	nuclear receptor coactivator 1	0.012
STAT5B	signal transducer and activator of transcription 5B	0.012
DSE	dermatan sulfate epimerase	0.012
FYN	FYN oncogene related to SRC, FGR, YES	0.012
SORBS2	sorbin and SH3 domain containing 2	0.012
SNX9	sorting nexin 9	0.012
AHNAK	AHNAK nucleoprotein	0.012
SMAD3	SMAD family member 3	0.012
NUMB	numb homolog (Drosophila)	0.012
HSPG2	heparan sulfate proteoglycan 2	0.011
ZNF71	zinc finger protein 71	0.011
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.011
FGA	fibrinogen alpha chain	0.011
FAM83C	family with sequence similarity 83, member C	0.011
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.011
G3BP2	GTPase activating protein (SH3 domain) binding protein 2	0.011
DAO	D-amino-acid oxidase	0.011
ADAM9	ADAM metallopeptidase domain 9	0.010
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.010
FGFR1	fibroblast growth factor receptor 1	0.010