IMP

Process View

Homo sapiens

4 genes annotated in human

Multi-species View

renal water homeostasis

GO:0003091

Renal process involved in the maintenance of an internal steady state of water in the body.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "renal water homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "renal water homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.985
KCTD17	potassium channel tetramerisation domain containing 17	0.873
GLTPD1	glycolipid transfer protein domain containing 1	0.733
ADAMTSL4	ADAMTS-like 4	0.718
HMOX2	heme oxygenase (decycling) 2	0.632
FAM107A	family with sequence similarity 107, member A	0.611
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.521
TRIP6	thyroid hormone receptor interactor 6	0.477
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.329
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.314	Human
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.302	Human
HOXA1	homeobox A1	0.241
CATSPER1	cation channel, sperm associated 1	0.166
A2M	alpha-2-macroglobulin	0.161
CSAD	cysteine sulfinic acid decarboxylase	0.134
EXT2	exostosin 2	0.133
HMGXB3	HMG box domain containing 3	0.132
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.104
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.091
WDR73	WD repeat domain 73	0.090
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.088
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.078
ZBTB16	zinc finger and BTB domain containing 16	0.076
TTR	transthyretin	0.070
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.070
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.067
FAM124B	family with sequence similarity 124B	0.066
LINGO1	leucine rich repeat and Ig domain containing 1	0.064
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.060
OSTF1	osteoclast stimulating factor 1	0.056
PLSCR4	phospholipid scramblase 4	0.055
PFDN1	prefoldin subunit 1	0.055
CRIP2	cysteine-rich protein 2	0.055
FABP1	fatty acid binding protein 1, liver	0.053
MDFI	MyoD family inhibitor	0.051
MPP1	membrane protein, palmitoylated 1, 55kDa	0.050
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.050
HYAL1	hyaluronoglucosaminidase 1	0.050
G6PC	glucose-6-phosphatase, catalytic subunit	0.047
A1BG	alpha-1-B glycoprotein	0.047
FGB	fibrinogen beta chain	0.047
KNG1	kininogen 1	0.045
PHF17	PHD finger protein 17	0.045
ELN	elastin	0.045
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.045
LRDD	leucine-rich repeats and death domain containing	0.044
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.044
COL4A5	collagen, type IV, alpha 5	0.043
AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.042
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.041
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.040
ZXDC	ZXD family zinc finger C	0.039
SIX1	SIX homeobox 1	0.039
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.039	Human
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.038
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.037
NGFR	nerve growth factor receptor	0.037
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.035
HAL	histidine ammonia-lyase	0.034
ADH6	alcohol dehydrogenase 6 (class V)	0.034
KLHL5	kelch-like 5 (Drosophila)	0.034
TMSB4X	thymosin beta 4, X-linked	0.033
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.033
GAS6	growth arrest-specific 6	0.032
ARG1	arginase, liver	0.031
SGTB	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta	0.030
COL8A1	collagen, type VIII, alpha 1	0.030
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.030
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.030
RDH16	retinol dehydrogenase 16 (all-trans)	0.030
LSM11	LSM11, U7 small nuclear RNA associated	0.029
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.028
APLP1	amyloid beta (A4) precursor-like protein 1	0.028
C8A	complement component 8, alpha polypeptide	0.028
EPHX2	epoxide hydrolase 2, cytoplasmic	0.028
NMT2	N-myristoyltransferase 2	0.027
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.027
DAO	D-amino-acid oxidase	0.027
C8B	complement component 8, beta polypeptide	0.026
ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	0.026
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.025
NKIRAS2	NFKB inhibitor interacting Ras-like 2	0.024
COL4A2	collagen, type IV, alpha 2	0.024
KRT4	keratin 4	0.024
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.024
PLG	plasminogen	0.024
CCND3	cyclin D3	0.023
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.022
CLDN5	claudin 5	0.021
C1orf65	chromosome 1 open reading frame 65	0.020
LRRC18	leucine rich repeat containing 18	0.020
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.020
LAMB2	laminin, beta 2 (laminin S)	0.020
F9	coagulation factor IX	0.020
DIO1	deiodinase, iodothyronine, type I	0.020
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.020
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.019
DEFB1	defensin, beta 1	0.019
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.019
MED31	mediator complex subunit 31	0.018
TMEM115	transmembrane protein 115	0.018
AQP7	aquaporin 7	0.018
PAH	phenylalanine hydroxylase	0.018
GEMIN7	gem (nuclear organelle) associated protein 7	0.018
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.018
HGD	homogentisate 1,2-dioxygenase	0.017
UNC119	unc-119 homolog (C. elegans)	0.017
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.017
IL22RA1	interleukin 22 receptor, alpha 1	0.017
C4BPA	complement component 4 binding protein, alpha	0.017
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.017
ZNF426	zinc finger protein 426	0.017
C9	complement component 9	0.017
NAT8	N-acetyltransferase 8 (GCN5-related, putative)	0.017
PDE4DIP	phosphodiesterase 4D interacting protein	0.017
GPR116	G protein-coupled receptor 116	0.017
C1orf116	chromosome 1 open reading frame 116	0.016
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.016
PRODH	proline dehydrogenase (oxidase) 1	0.016
VTCN1	V-set domain containing T cell activation inhibitor 1	0.016
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.016
SP110	SP110 nuclear body protein	0.016
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.016
PIP	prolactin-induced protein	0.016
KRT13	keratin 13	0.016
TFF3	trefoil factor 3 (intestinal)	0.016
DPYS	dihydropyrimidinase	0.016
HNF4A	hepatocyte nuclear factor 4, alpha	0.016
SDF4	stromal cell derived factor 4	0.016
CALCOCO1	calcium binding and coiled-coil domain 1	0.016
GSTA3	glutathione S-transferase alpha 3	0.016
CARHSP1	calcium regulated heat stable protein 1, 24kDa	0.016
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.016
HPD	4-hydroxyphenylpyruvate dioxygenase	0.015
LPA	lipoprotein, Lp(a)	0.015
BCAS3	breast carcinoma amplified sequence 3	0.015
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.015
TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)	0.015
EGFL7	EGF-like-domain, multiple 7	0.015
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.015
C19orf60	chromosome 19 open reading frame 60	0.015
MAST2	microtubule associated serine/threonine kinase 2	0.015
CENPB	centromere protein B, 80kDa	0.015
ZNF707	zinc finger protein 707	0.015
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.015
GEMIN8	gem (nuclear organelle) associated protein 8	0.015
SDPR	serum deprivation response	0.015
APOF	apolipoprotein F	0.015
GSTT1	glutathione S-transferase theta 1	0.015
CLEC3B	C-type lectin domain family 3, member B	0.015
KHK	ketohexokinase (fructokinase)	0.014
AADAC	arylacetamide deacetylase (esterase)	0.014
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.014
FUT3	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)	0.014
C6	complement component 6	0.014
GDF9	growth differentiation factor 9	0.014
FKBP9	FK506 binding protein 9, 63 kDa	0.014
F13B	coagulation factor XIII, B polypeptide	0.014
MMRN2	multimerin 2	0.014
PLXNA3	plexin A3	0.014
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.014
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.013
C8orf48	chromosome 8 open reading frame 48	0.013
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.013
FHL3	four and a half LIM domains 3	0.013
LNX1	ligand of numb-protein X 1	0.013
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.013
CES1	carboxylesterase 1	0.013
ORM1	orosomucoid 1	0.013
BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	0.013
SCGB2A1	secretoglobin, family 2A, member 1	0.013
BHMT	betaine--homocysteine S-methyltransferase	0.013
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.013
ZBTB7C	zinc finger and BTB domain containing 7C	0.013
F5	coagulation factor V (proaccelerin, labile factor)	0.013
MOSC1	MOCO sulphurase C-terminal domain containing 1	0.013
CRISP3	cysteine-rich secretory protein 3	0.013
DOCK7	dedicator of cytokinesis 7	0.012
APOC3	apolipoprotein C-III	0.012
LIPC	lipase, hepatic	0.012
FMO4	flavin containing monooxygenase 4	0.012
NUDT18	nudix (nucleoside diphosphate linked moiety X)-type motif 18	0.012
HABP4	hyaluronan binding protein 4	0.012
RHPN1	rhophilin, Rho GTPase binding protein 1	0.012
CYB561D2	cytochrome b-561 domain containing 2	0.012
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	0.012
ZNF440	zinc finger protein 440	0.012
MASP2	mannan-binding lectin serine peptidase 2	0.012
ZER1	zer-1 homolog (C. elegans)	0.012
STK16	serine/threonine kinase 16	0.012
HHEX	hematopoietically expressed homeobox	0.012
CDHR5	cadherin-related family member 5	0.012
EHD2	EH-domain containing 2	0.012
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.012
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.012
SDC1	syndecan 1	0.011
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.011
WDR45	WD repeat domain 45	0.011
C8G	complement component 8, gamma polypeptide	0.011
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.011
MGAM	maltase-glucoamylase (alpha-glucosidase)	0.011
EMP2	epithelial membrane protein 2	0.011
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.011
ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	0.011
TMPRSS2	transmembrane protease, serine 2	0.011
PRLR	prolactin receptor	0.011
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.011
HHLA2	HERV-H LTR-associating 2	0.011
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.011
FBLN5	fibulin 5	0.011
OTC	ornithine carbamoyltransferase	0.011
ETNK2	ethanolamine kinase 2	0.011
MSMB	microseminoprotein, beta-	0.011
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.011
ANGPT2	angiopoietin 2	0.011
HPN	hepsin	0.011
VPS11	vacuolar protein sorting 11 homolog (S. cerevisiae)	0.011
C10orf116	chromosome 10 open reading frame 116	0.011
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.010
COLEC10	collectin sub-family member 10 (C-type lectin)	0.010
ZNF185	zinc finger protein 185 (LIM domain)	0.010
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.010
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.010	Human
DNASE1L3	deoxyribonuclease I-like 3	0.010
CDA	cytidine deaminase	0.010
ORM2	orosomucoid 2	0.010
CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1	0.010
C5orf55	chromosome 5 open reading frame 55	0.010
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.010
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.010
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.010
TNS1	tensin 1	0.010
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	0.010
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.010
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.010
SLC14A1	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)	0.010