IMP
Process View
negative regulation of actin nucleation
Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of actin nucleation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.928 | ||
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.808 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.479 | ||
| TPM4 | tropomyosin 4 | 0.367 | ||
| SNX9 | sorting nexin 9 | 0.230 | ||
| PRLHR | prolactin releasing hormone receptor | 0.141 | ||
| SNX2 | sorting nexin 2 | 0.137 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.115 | ||
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.112 | ||
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.111 | ||
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.099 | ||
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.085 | ||
| ATXN7L3 | ataxin 7-like 3 | 0.084 | ||
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.080 | ||
| COTL1 | coactosin-like 1 (Dictyostelium) | 0.077 | ||
| DNM2 | dynamin 2 | 0.077 | ||
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.076 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.076 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.072 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.052 | ||
| ZYX | zyxin | 0.049 | ||
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.039 | ||
| CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.039 | ||
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.037 | ||
| PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | 0.034 | ||
| WDR1 | WD repeat domain 1 | 0.033 | ||
| MYH9 | myosin, heavy chain 9, non-muscle | 0.031 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.029 | ||
| SNX6 | sorting nexin 6 | 0.028 | ||
| CFL1 | cofilin 1 (non-muscle) | 0.027 | ||
| NCF2 | neutrophil cytosolic factor 2 | 0.027 | ||
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.027 | ||
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.026 | ||
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.022 | ||
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.022 | ||
| ACCN2 | amiloride-sensitive cation channel 2, neuronal | 0.022 | ||
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.022 | ||
| ACTB | actin, beta | 0.021 | ||
| PRKCG | protein kinase C, gamma | 0.021 | ||
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | 0.020 | ||
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.020 | ||
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.020 | ||
| ARHGAP4 | Rho GTPase activating protein 4 | 0.019 | ||
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.019 | ||
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.018 | ||
| TUBB6 | tubulin, beta 6 | 0.018 | ||
| CTTN | cortactin | 0.017 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.017 | ||
| SH3BGRL3 | SH3 domain binding glutamic acid-rich protein like 3 | 0.017 | ||
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.016 | ||
| TRIP10 | thyroid hormone receptor interactor 10 | 0.016 | Fly | |
| ACTG1 | actin, gamma 1 | 0.016 | ||
| MMGT1 | membrane magnesium transporter 1 | 0.015 | ||
| RHOG | ras homolog gene family, member G (rho G) | 0.014 | ||
| LASP1 | LIM and SH3 protein 1 | 0.014 | ||
| ZDHHC24 | zinc finger, DHHC-type containing 24 | 0.014 | ||
| RAB1B | RAB1B, member RAS oncogene family | 0.014 | ||
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.014 | ||
| UNC119 | unc-119 homolog (C. elegans) | 0.013 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.013 | ||
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.013 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.013 | ||
| BAIAP2 | BAI1-associated protein 2 | 0.013 | ||
| CIC | capicua homolog (Drosophila) | 0.013 | ||
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.013 | ||
| MAN2B1 | mannosidase, alpha, class 2B, member 1 | 0.013 | ||
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.012 | ||
| ARHGAP9 | Rho GTPase activating protein 9 | 0.012 | ||
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.012 | ||
| MSN | moesin | 0.012 | ||
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) | 0.011 | ||
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.011 | ||
| CNN2 | calponin 2 | 0.011 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.011 | ||
| ITK | IL2-inducible T-cell kinase | 0.011 | ||
| RGS19 | regulator of G-protein signaling 19 | 0.011 | ||
| DNM1 | dynamin 1 | 0.011 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.011 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.011 | ||
| TAGLN2 | transgelin 2 | 0.011 | ||
| ACTN1 | actinin, alpha 1 | 0.011 | ||
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.010 | ||
| ARHGAP17 | Rho GTPase activating protein 17 | 0.010 |