IMP

Process View

Homo sapiens

3 genes annotated in human

positive regulation of dermatome development

Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of dermatome development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of dermatome development" (in gray)

Name	Description	Probability	Func Analog Organism
FZD1	frizzled homolog 1 (Drosophila)	1.000
FGF18	fibroblast growth factor 18	0.855
LRP6	low density lipoprotein receptor-related protein 6	0.787
WNT1	wingless-type MMTV integration site family, member 1	0.390
WNT3	wingless-type MMTV integration site family, member 3	0.354	Human
WIF1	WNT inhibitory factor 1	0.346
FZD8	frizzled homolog 8 (Drosophila)	0.302
SFRP1	secreted frizzled-related protein 1	0.279
IHH	Indian hedgehog	0.213
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.189
FZD2	frizzled homolog 2 (Drosophila)	0.156
EXOC3L2	exocyst complex component 3-like 2	0.155
WNT10A	wingless-type MMTV integration site family, member 10A	0.141	Human
FGF8	fibroblast growth factor 8 (androgen-induced)	0.132
NPAS1	neuronal PAS domain protein 1	0.110
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.108
HES2	hairy and enhancer of split 2 (Drosophila)	0.102
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.085
HMX1	H6 family homeobox 1	0.080
GUCA2A	guanylate cyclase activator 2A (guanylin)	0.071
WNT7A	wingless-type MMTV integration site family, member 7A	0.068	Human
HOXC8	homeobox C8	0.068
FGF3	fibroblast growth factor 3	0.066
LHX3	LIM homeobox 3	0.064
ACAN	aggrecan	0.062
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.062
HOXD1	homeobox D1	0.058
FIBCD1	fibrinogen C domain containing 1	0.056
USH1G	Usher syndrome 1G (autosomal recessive)	0.055
FOXL1	forkhead box L1	0.054
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.054
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.053
WNT4	wingless-type MMTV integration site family, member 4	0.053
AQP5	aquaporin 5	0.053
EVPL	envoplakin	0.051
SHH	sonic hedgehog	0.050
FGF19	fibroblast growth factor 19	0.048
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.048
TLX1	T-cell leukemia homeobox 1	0.047
LBX1	ladybird homeobox 1	0.045
DLX4	distal-less homeobox 4	0.043
HOXD13	homeobox D13	0.042
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.042
HOXD11	homeobox D11	0.037
GALR3	galanin receptor 3	0.037
FOXF2	forkhead box F2	0.037
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.036
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.036
NKX2-1	NK2 homeobox 1	0.034
WNT9B	wingless-type MMTV integration site family, member 9B	0.034	Human
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.034
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.034
TLX3	T-cell leukemia homeobox 3	0.033
SOX1	SRY (sex determining region Y)-box 1	0.033
SDC2	syndecan 2	0.033
WNT6	wingless-type MMTV integration site family, member 6	0.032	Human
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.032
HOXA11	homeobox A11	0.032
BHLHE23	basic helix-loop-helix family, member e23	0.032
FGF4	fibroblast growth factor 4	0.031
WNT2B	wingless-type MMTV integration site family, member 2B	0.031	Human
NKD2	naked cuticle homolog 2 (Drosophila)	0.031
EFNA3	ephrin-A3	0.030
SIM2	single-minded homolog 2 (Drosophila)	0.030
WNT11	wingless-type MMTV integration site family, member 11	0.029	Human
GDNF	glial cell derived neurotrophic factor	0.029
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.029
GLIS1	GLIS family zinc finger 1	0.029
CDX1	caudal type homeobox 1	0.028
FOXD3	forkhead box D3	0.027
CCDC48	coiled-coil domain containing 48	0.027
IRX4	iroquois homeobox 4	0.027
C1QL1	complement component 1, q subcomponent-like 1	0.027
SOX21	SRY (sex determining region Y)-box 21	0.026
CDX2	caudal type homeobox 2	0.026
FZD10	frizzled homolog 10 (Drosophila)	0.026
CRTAC1	cartilage acidic protein 1	0.026
HOXB8	homeobox B8	0.025
OTP	orthopedia homeobox	0.025
HES5	hairy and enhancer of split 5 (Drosophila)	0.025
PAX8	paired box 8	0.025
S1PR5	sphingosine-1-phosphate receptor 5	0.024
PITX1	paired-like homeodomain 1	0.024
KREMEN2	kringle containing transmembrane protein 2	0.024
CACNG4	calcium channel, voltage-dependent, gamma subunit 4	0.024
WNT16	wingless-type MMTV integration site family, member 16	0.023	Human
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.023
RSPO4	R-spondin family, member 4	0.023
HYAL1	hyaluronoglucosaminidase 1	0.023
DUOX1	dual oxidase 1	0.023
SLC29A4	solute carrier family 29 (nucleoside transporters), member 4	0.022
WNT2	wingless-type MMTV integration site family member 2	0.022	Human
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.022
SIX2	SIX homeobox 2	0.022
WNT10B	wingless-type MMTV integration site family, member 10B	0.022	Human
FOXB1	forkhead box B1	0.022
WNT7B	wingless-type MMTV integration site family, member 7B	0.022	Human
NKX2-2	NK2 homeobox 2	0.022
NKX3-2	NK3 homeobox 2	0.021
NKD1	naked cuticle homolog 1 (Drosophila)	0.021
CDHR1	cadherin-related family member 1	0.021
SMO	smoothened homolog (Drosophila)	0.021
PITX2	paired-like homeodomain 2	0.021
HRH3	histamine receptor H3	0.020
CRLF1	cytokine receptor-like factor 1	0.020
VSTM2L	V-set and transmembrane domain containing 2 like	0.020
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.020
NKPD1	NTPase, KAP family P-loop domain containing 1	0.020
EDA	ectodysplasin A	0.020
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.020
LBP	lipopolysaccharide binding protein	0.019
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.019
SAMD11	sterile alpha motif domain containing 11	0.019
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.019
TG	thyroglobulin	0.019
POU3F1	POU class 3 homeobox 1	0.019
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.018
GUCY2D	guanylate cyclase 2D, membrane (retina-specific)	0.018
TBX5	T-box 5	0.018
MNX1	motor neuron and pancreas homeobox 1	0.018
TMEM190	transmembrane protein 190	0.018
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.018
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	0.018
NTF4	neurotrophin 4	0.018
HOXC12	homeobox C12	0.018
ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	0.017
CHRD	chordin	0.017
SLC22A6	solute carrier family 22 (organic anion transporter), member 6	0.017
CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.017
LMO1	LIM domain only 1 (rhombotin 1)	0.017
C17orf82	chromosome 17 open reading frame 82	0.017
GATA5	GATA binding protein 5	0.017
HOXC11	homeobox C11	0.017
MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	0.017
FOXL2	forkhead box L2	0.017
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.017
PRPH	peripherin	0.017
NPPC	natriuretic peptide C	0.017
INSM2	insulinoma-associated 2	0.017
RAX	retina and anterior neural fold homeobox	0.017
GPR143	G protein-coupled receptor 143	0.017
GAD1	glutamate decarboxylase 1 (brain, 67kDa)	0.016
VSX1	visual system homeobox 1	0.016
TNFRSF13C	tumor necrosis factor receptor superfamily, member 13C	0.016
OVGP1	oviductal glycoprotein 1, 120kDa	0.016
RTN4R	reticulon 4 receptor	0.016
EPHB3	EPH receptor B3	0.016
RGS9BP	regulator of G protein signaling 9 binding protein	0.016
SLC30A2	solute carrier family 30 (zinc transporter), member 2	0.016
DLL4	delta-like 4 (Drosophila)	0.016
COL10A1	collagen, type X, alpha 1	0.016
BMP4	bone morphogenetic protein 4	0.016
RASL10A	RAS-like, family 10, member A	0.015
JPH3	junctophilin 3	0.015
RHBG	Rh family, B glycoprotein (gene/pseudogene)	0.015
HOXD9	homeobox D9	0.015
SLITRK2	SLIT and NTRK-like family, member 2	0.015
DSC3	desmocollin 3	0.015
NXPH4	neurexophilin 4	0.015
HOXB13	homeobox B13	0.015
HOXD10	homeobox D10	0.015
KRBA1	KRAB-A domain containing 1	0.015
BNC1	basonuclin 1	0.015
COL2A1	collagen, type II, alpha 1	0.015
SMTNL2	smoothelin-like 2	0.015
PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	0.014
EN1	engrailed homeobox 1	0.014
NPAS4	neuronal PAS domain protein 4	0.014
FEZF2	FEZ family zinc finger 2	0.014
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.014
COL4A6	collagen, type IV, alpha 6	0.014
DAPK2	death-associated protein kinase 2	0.014
SLC6A5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	0.014
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.014
EPHB2	EPH receptor B2	0.014
BARHL1	BarH-like homeobox 1	0.014
OVOL1	ovo-like 1(Drosophila)	0.014
HMX2	H6 family homeobox 2	0.014
NEUROG2	neurogenin 2	0.014
TTC22	tetratricopeptide repeat domain 22	0.014
OCA2	oculocutaneous albinism II	0.014
SFRP5	secreted frizzled-related protein 5	0.014
DIO3	deiodinase, iodothyronine, type III	0.014
GPR20	G protein-coupled receptor 20	0.014
RARG	retinoic acid receptor, gamma	0.014
TKTL1	transketolase-like 1	0.014
OLIG2	oligodendrocyte lineage transcription factor 2	0.014
LMX1A	LIM homeobox transcription factor 1, alpha	0.014
FAM176A	family with sequence similarity 176, member A	0.014
CARD10	caspase recruitment domain family, member 10	0.014
ESPN	espin	0.014
BHMT	betaine--homocysteine S-methyltransferase	0.014
PRRX2	paired related homeobox 2	0.014
POU4F3	POU class 4 homeobox 3	0.014
HOXC5	homeobox C5	0.014
VGLL2	vestigial like 2 (Drosophila)	0.014
ALOX12	arachidonate 12-lipoxygenase	0.013
PAX1	paired box 1	0.013
AHDC1	AT hook, DNA binding motif, containing 1	0.013
KRT4	keratin 4	0.013
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.013
PTH2	parathyroid hormone 2	0.013
FBXL22	F-box and leucine-rich repeat protein 22	0.013
PLCD1	phospholipase C, delta 1	0.013
RSPO1	R-spondin homolog (Xenopus laevis)	0.013
FAM163A	family with sequence similarity 163, member A	0.013
KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	0.013
LYPD3	LY6/PLAUR domain containing 3	0.013
TFAP2D	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)	0.013
ALX4	ALX homeobox 4	0.013
SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	0.013
OTX1	orthodenticle homeobox 1	0.013
CDH22	cadherin 22, type 2	0.013
CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.013
SRRM4	serine/arginine repetitive matrix 4	0.013
PAX2	paired box 2	0.013
KLHL35	kelch-like 35 (Drosophila)	0.012
CHST8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.012
HIST1H1D	histone cluster 1, H1d	0.012
HOXA4	homeobox A4	0.012
SCARF2	scavenger receptor class F, member 2	0.012
ALOX12B	arachidonate 12-lipoxygenase, 12R type	0.012
HOXD4	homeobox D4	0.012
MOGAT3	monoacylglycerol O-acyltransferase 3	0.012
KRTDAP	keratinocyte differentiation-associated protein	0.012
KLF14	Kruppel-like factor 14	0.012
FOXD2	forkhead box D2	0.012
AVPR1B	arginine vasopressin receptor 1B	0.012
KLHL14	kelch-like 14 (Drosophila)	0.012
NPFFR1	neuropeptide FF receptor 1	0.012
PLCH2	phospholipase C, eta 2	0.012
TBX3	T-box 3	0.012
SIX3	SIX homeobox 3	0.012
BFSP1	beaded filament structural protein 1, filensin	0.012
SYT12	synaptotagmin XII	0.012
CST1	cystatin SN	0.012
STAC2	SH3 and cysteine rich domain 2	0.011
TACR1	tachykinin receptor 1	0.011
LTK	leukocyte receptor tyrosine kinase	0.011
DRD4	dopamine receptor D4	0.011
KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1	0.011
C1orf194	chromosome 1 open reading frame 194	0.011
GRIK3	glutamate receptor, ionotropic, kainate 3	0.011
DMRT3	doublesex and mab-3 related transcription factor 3	0.011
SLC45A1	solute carrier family 45, member 1	0.011
C3orf18	chromosome 3 open reading frame 18	0.011
REG1B	regenerating islet-derived 1 beta	0.011
SP6	Sp6 transcription factor	0.011
ICOSLG	inducible T-cell co-stimulator ligand	0.011
CD70	CD70 molecule	0.011
DMRTB1	DMRT-like family B with proline-rich C-terminal, 1	0.011
MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator	0.011
ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17	0.011
JAG2	jagged 2	0.011
PTK7	PTK7 protein tyrosine kinase 7	0.011
ADRA1D	adrenergic, alpha-1D-, receptor	0.011
SHROOM1	shroom family member 1	0.011
PRSS16	protease, serine, 16 (thymus)	0.011
GFI1	growth factor independent 1 transcription repressor	0.011
HOXD3	homeobox D3	0.011
NODAL	nodal homolog (mouse)	0.011
EPHA8	EPH receptor A8	0.011
CRABP2	cellular retinoic acid binding protein 2	0.011
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.011
HES7	hairy and enhancer of split 7 (Drosophila)	0.011
HOXB1	homeobox B1	0.011
EMX2	empty spiracles homeobox 2	0.011
ONECUT2	one cut homeobox 2	0.011
KLC3	kinesin light chain 3	0.011
PALM	paralemmin	0.010
FAM163B	family with sequence similarity 163, member B	0.010
RHOD	ras homolog gene family, member D	0.010
FAM69C	family with sequence similarity 69, member C	0.010
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.010
CCDC155	coiled-coil domain containing 155	0.010
MST1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.010
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.010
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.010
KLK10	kallikrein-related peptidase 10	0.010
C9orf91	chromosome 9 open reading frame 91	0.010
PYY	peptide YY	0.010
EN2	engrailed homeobox 2	0.010
CTF1	cardiotrophin 1	0.010
KCNK12	potassium channel, subfamily K, member 12	0.010
NRTN	neurturin	0.010
MKX	mohawk homeobox	0.010
KCNK7	potassium channel, subfamily K, member 7	0.010
ADAMTSL5	ADAMTS-like 5	0.010
NEO1	neogenin 1	0.010
HOXB9	homeobox B9	0.010
GLDC	glycine dehydrogenase (decarboxylating)	0.010
HOXB4	homeobox B4	0.010
LHX2	LIM homeobox 2	0.010
INHBB	inhibin, beta B	0.010
LHX6	LIM homeobox 6	0.010
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.010
HOXA13	homeobox A13	0.010
LPAR3	lysophosphatidic acid receptor 3	0.010
PRMT8	protein arginine methyltransferase 8	0.010
ADAMTS16	ADAM metallopeptidase with thrombospondin type 1 motif, 16	0.010
CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	0.010
ASIP	agouti signaling protein	0.010