IMP

Process View

Homo sapiens

2 genes annotated in human

Multi-species View

negative regulation of lymphocyte chemotaxis

GO:1901624

Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of lymphocyte chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of lymphocyte chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000
CCL4	chemokine (C-C motif) ligand 4	0.998	Human
IL8	interleukin 8	0.998
CCL2	chemokine (C-C motif) ligand 2	0.991
CCL5	chemokine (C-C motif) ligand 5	0.988	Human
IL1B	interleukin 1, beta	0.983
CXCL9	chemokine (C-X-C motif) ligand 9	0.978
CXCL2	chemokine (C-X-C motif) ligand 2	0.974
CXCL3	chemokine (C-X-C motif) ligand 3	0.946
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.943
IL6	interleukin 6 (interferon, beta 2)	0.942
CCL8	chemokine (C-C motif) ligand 8	0.915	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.904
IDE	insulin-degrading enzyme	0.876
DPP4	dipeptidyl-peptidase 4	0.813
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.771	Human
CCR7	chemokine (C-C motif) receptor 7	0.682
CXCL11	chemokine (C-X-C motif) ligand 11	0.673
TRAF1	TNF receptor-associated factor 1	0.667
CCL22	chemokine (C-C motif) ligand 22	0.646	Human
IFNG	interferon, gamma	0.641
CCL20	chemokine (C-C motif) ligand 20	0.591	Human
ICAM1	intercellular adhesion molecule 1	0.528
CCL19	chemokine (C-C motif) ligand 19	0.490	Human
CCL13	chemokine (C-C motif) ligand 13	0.470	Human
CD83	CD83 molecule	0.446
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.406
RGS1	regulator of G-protein signaling 1	0.385
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.373
CXCL13	chemokine (C-X-C motif) ligand 13	0.360
CCL3	chemokine (C-C motif) ligand 3	0.353	Human
CXCL5	chemokine (C-X-C motif) ligand 5	0.316
IL7R	interleukin 7 receptor	0.291
CCL7	chemokine (C-C motif) ligand 7	0.286	Human
IL2RB	interleukin 2 receptor, beta	0.270
IL10	interleukin 10	0.258
TNF	tumor necrosis factor	0.258
CCR4	chemokine (C-C motif) receptor 4	0.243
SELE	selectin E	0.234
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.231
IL1RN	interleukin 1 receptor antagonist	0.208
VCAM1	vascular cell adhesion molecule 1	0.200
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.188
UBD	ubiquitin D	0.181
CH25H	cholesterol 25-hydroxylase	0.168
PLAUR	plasminogen activator, urokinase receptor	0.163
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.146
CCR1	chemokine (C-C motif) receptor 1	0.144
BCL2A1	BCL2-related protein A1	0.114
LAMP3	lysosomal-associated membrane protein 3	0.104
FPR3	formyl peptide receptor 3	0.095
CD69	CD69 molecule	0.082
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.077
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.073
CCL11	chemokine (C-C motif) ligand 11	0.071	Human
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.066
IL18RAP	interleukin 18 receptor accessory protein	0.066
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.065
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.057
NNMT	nicotinamide N-methyltransferase	0.057
INHBA	inhibin, beta A	0.056
DARC	Duffy blood group, chemokine receptor	0.055
CD80	CD80 molecule	0.055
GNLY	granulysin	0.054
SRGN	serglycin	0.052
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.052
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.051
IL1R2	interleukin 1 receptor, type II	0.049
EBI3	Epstein-Barr virus induced 3	0.047
IDO1	indoleamine 2,3-dioxygenase 1	0.047
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.046
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.045
IL1A	interleukin 1, alpha	0.043
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.043
SLAMF8	SLAM family member 8	0.043
ADAMDEC1	ADAM-like, decysin 1	0.042
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.042
CCR3	chemokine (C-C motif) receptor 3	0.041
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.041
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.041
C2	complement component 2	0.041
C1QB	complement component 1, q subcomponent, B chain	0.040
AQP9	aquaporin 9	0.040
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.039
IL2RG	interleukin 2 receptor, gamma	0.037
SOD2	superoxide dismutase 2, mitochondrial	0.037
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.034
CD40	CD40 molecule, TNF receptor superfamily member 5	0.034
CCL17	chemokine (C-C motif) ligand 17	0.033	Human
SLAMF7	SLAM family member 7	0.032
STAT4	signal transducer and activator of transcription 4	0.031
RGS16	regulator of G-protein signaling 16	0.030
IL2RA	interleukin 2 receptor, alpha	0.029
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.029
CSF1	colony stimulating factor 1 (macrophage)	0.029
IL10RA	interleukin 10 receptor, alpha	0.029
MSC	musculin	0.029
IL21R	interleukin 21 receptor	0.028
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.027
CXCR6	chemokine (C-X-C motif) receptor 6	0.027
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.027
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.026
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.026
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.026
PI3	peptidase inhibitor 3, skin-derived	0.026
CCL21	chemokine (C-C motif) ligand 21	0.025
C1QA	complement component 1, q subcomponent, A chain	0.025
ARRB1	arrestin, beta 1	0.024
CCRL2	chemokine (C-C motif) receptor-like 2	0.024
CXCR3	chemokine (C-X-C motif) receptor 3	0.024
IL18R1	interleukin 18 receptor 1	0.023
GPR109B	G protein-coupled receptor 109B	0.023
NKG7	natural killer cell group 7 sequence	0.021
CCL1	chemokine (C-C motif) ligand 1	0.021	Human
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.020
BATF	basic leucine zipper transcription factor, ATF-like	0.020
IRF4	interferon regulatory factor 4	0.020
IL13	interleukin 13	0.020
ZC3H12A	zinc finger CCCH-type containing 12A	0.019
PDPN	podoplanin	0.018
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.018
CD160	CD160 molecule	0.018
PRDM1	PR domain containing 1, with ZNF domain	0.017
CD48	CD48 molecule	0.017
OSMR	oncostatin M receptor	0.017
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.017
DUSP2	dual specificity phosphatase 2	0.017
EGR2	early growth response 2	0.017
CD40LG	CD40 ligand	0.016
PTX3	pentraxin 3, long	0.016
APOC1	apolipoprotein C-I	0.016
C5AR1	complement component 5a receptor 1	0.016
LRRC32	leucine rich repeat containing 32	0.016
IER3	immediate early response 3	0.015
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.015
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.015
CD1B	CD1b molecule	0.015
IL1F5	interleukin 1 family, member 5 (delta)	0.015
GZMK	granzyme K (granzyme 3; tryptase II)	0.015
TNFSF9	tumor necrosis factor (ligand) superfamily, member 9	0.015
CLEC10A	C-type lectin domain family 10, member A	0.015
TREM1	triggering receptor expressed on myeloid cells 1	0.014
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.014
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.014
SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.014
NLRP3	NLR family, pyrin domain containing 3	0.014
RUNX3	runt-related transcription factor 3	0.014
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.014
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.014
TFPI2	tissue factor pathway inhibitor 2	0.014
IL11	interleukin 11	0.014
MMP19	matrix metallopeptidase 19	0.014
G0S2	G0/G1switch 2	0.013
SLAMF1	signaling lymphocytic activation molecule family member 1	0.013
TM7SF4	transmembrane 7 superfamily member 4	0.013
CCL23	chemokine (C-C motif) ligand 23	0.013	Human
PLAU	plasminogen activator, urokinase	0.013
SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.013
PLEK	pleckstrin	0.013
IL15RA	interleukin 15 receptor, alpha	0.013
TFEC	transcription factor EC	0.012
IL3RA	interleukin 3 receptor, alpha (low affinity)	0.012
CCBP2	chemokine binding protein 2	0.012
IL32	interleukin 32	0.012
DNASE1L3	deoxyribonuclease I-like 3	0.011
CSF3	colony stimulating factor 3 (granulocyte)	0.011
GPR183	G protein-coupled receptor 183	0.011
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.011
GPR84	G protein-coupled receptor 84	0.011
PTGES	prostaglandin E synthase	0.011
SCARF1	scavenger receptor class F, member 1	0.011
SOCS3	suppressor of cytokine signaling 3	0.011
KYNU	kynureninase	0.011
IL4I1	interleukin 4 induced 1	0.011
IL1F9	interleukin 1 family, member 9	0.011
IL1R1	interleukin 1 receptor, type I	0.011
CX3CL1	chemokine (C-X3-C motif) ligand 1	0.011
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.010
CHIT1	chitinase 1 (chitotriosidase)	0.010
TLR2	toll-like receptor 2	0.010
RGL1	ral guanine nucleotide dissociation stimulator-like 1	0.010
BDKRB1	bradykinin receptor B1	0.010
IGL@	immunoglobulin lambda locus	0.010
PRF1	perforin 1 (pore forming protein)	0.010
EDN1	endothelin 1	0.010
RRAD	Ras-related associated with diabetes	0.010
GPR171	G protein-coupled receptor 171	0.010
CST7	cystatin F (leukocystatin)	0.010