IMP

Process View

Homo sapiens

3 genes annotated in human

chemokine c x c motif ligand 2 production

The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chemokine c x c motif ligand 2 production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "chemokine c x c motif ligand 2 production" (in gray)

Name	Description	Probability	Func Analog Organism
HDAC2	histone deacetylase 2	0.997
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.326
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.226
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.196
IER2	immediate early response 2	0.177
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.136
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.133
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.127
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.126
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.105
DUSP1	dual specificity phosphatase 1	0.101
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.100
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.098
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.092
CTBP1	C-terminal binding protein 1	0.076
HLA-DMB	major histocompatibility complex, class II, DM beta	0.067
TRADD	TNFRSF1A-associated via death domain	0.066
ATF3	activating transcription factor 3	0.065
MAPK7	mitogen-activated protein kinase 7	0.058
TLR4	toll-like receptor 4	0.053
RCOR1	REST corepressor 1	0.053
CXCR4	chemokine (C-X-C motif) receptor 4	0.047
SAMHD1	SAM domain and HD domain 1	0.044
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.044
ASRGL1	asparaginase like 1	0.044
IRAK4	interleukin-1 receptor-associated kinase 4	0.043
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.041
RBBP4	retinoblastoma binding protein 4	0.041
JUN	jun proto-oncogene	0.039
SAP30	Sin3A-associated protein, 30kDa	0.037
MYD88	myeloid differentiation primary response gene (88)	0.037
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.036
FOSL2	FOS-like antigen 2	0.035
MAPK14	mitogen-activated protein kinase 14	0.028
ESR1	estrogen receptor 1	0.026
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.025
KLF2	Kruppel-like factor 2 (lung)	0.024	Human
KLF4	Kruppel-like factor 4 (gut)	0.023
CHD4	chromodomain helicase DNA binding protein 4	0.022
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.022
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.022
TRAF7	TNF receptor-associated factor 7	0.022
CUX1	cut-like homeobox 1	0.021
TRAF1	TNF receptor-associated factor 1	0.020
RBBP7	retinoblastoma binding protein 7	0.020
RHOB	ras homolog gene family, member B	0.020
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.019
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.018
KAT2B	K(lysine) acetyltransferase 2B	0.017
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.017
HEMGN	hemogen	0.017
INADL	InaD-like (Drosophila)	0.016
POLH	polymerase (DNA directed), eta	0.016
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.015
ANXA1	annexin A1	0.015
FADD	Fas (TNFRSF6)-associated via death domain	0.015
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.015
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.014
HDAC3	histone deacetylase 3	0.014
ING2	inhibitor of growth family, member 2	0.014
GADD45B	growth arrest and DNA-damage-inducible, beta	0.014
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.014
JUNB	jun B proto-oncogene	0.014
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.013
TSC22D3	TSC22 domain family, member 3	0.013
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.013
TRAF2	TNF receptor-associated factor 2	0.013
HCFC1	host cell factor C1 (VP16-accessory protein)	0.013
EMP1	epithelial membrane protein 1	0.013
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.013
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.012
TGIF1	TGFB-induced factor homeobox 1	0.012
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.012
CYR61	cysteine-rich, angiogenic inducer, 61	0.011
CSRNP1	cysteine-serine-rich nuclear protein 1	0.011
CBX5	chromobox homolog 5	0.011
ZFP36L2	zinc finger protein 36, C3H type-like 2	0.011
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.011
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.011
PROCR	protein C receptor, endothelial	0.011
MYADM	myeloid-associated differentiation marker	0.011
CMIP	c-Maf-inducing protein	0.011
IKZF1	IKAROS family zinc finger 1 (Ikaros)	0.011
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.011
LAPTM5	lysosomal protein transmembrane 5	0.010
CDYL	chromodomain protein, Y-like	0.010
JOSD1	Josephin domain containing 1	0.010
EIF1	eukaryotic translation initiation factor 1	0.010
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.010
MTA1	metastasis associated 1	0.010