IMP

Process View

Homo sapiens

1 genes annotated in human

genetic imprinting

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "genetic imprinting"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "genetic imprinting" (in gray)

Name	Description	Probability	Func Analog Organism
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.948
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.926
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.910
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.810	Mouse
FBXL12	F-box and leucine-rich repeat protein 12	0.787
EED	embryonic ectoderm development	0.630	Mouse
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.629	Mouse
GSK3B	glycogen synthase kinase 3 beta	0.382	Mouse
AXIN1	axin 1	0.307	Mouse
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.295
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.245
SMC1A	structural maintenance of chromosomes 1A	0.228
HIPK2	homeodomain interacting protein kinase 2	0.204
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.195
HDAC1	histone deacetylase 1	0.186
ATM	ataxia telangiectasia mutated	0.111
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.111
ARID4B	AT rich interactive domain 4B (RBP1-like)	0.110	Mouse
ARID1A	AT rich interactive domain 1A (SWI-like)	0.102
GSK3A	glycogen synthase kinase 3 alpha	0.098	Mouse
ARID4A	AT rich interactive domain 4A (RBP1-like)	0.095	Mouse
IRS1	insulin receptor substrate 1	0.081
CSNK1E	casein kinase 1, epsilon	0.076
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.073
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.072
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.067
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.066
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.065
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.062
SMAD7	SMAD family member 7	0.057
RSBN1	round spermatid basic protein 1	0.049
RB1	retinoblastoma 1	0.049
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.049
SIRT1	sirtuin 1	0.046
AXIN2	axin 2	0.045
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.041
ARRB1	arrestin, beta 1	0.038
RB1CC1	RB1-inducible coiled-coil 1	0.037
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.034
CHD8	chromodomain helicase DNA binding protein 8	0.033
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.032
MAGEA2	melanoma antigen family A, 2	0.031
WAC	WW domain containing adaptor with coiled-coil	0.030
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.028
KLHL24	kelch-like 24 (Drosophila)	0.028
HDAC4	histone deacetylase 4	0.028
SAP30	Sin3A-associated protein, 30kDa	0.028
MBD1	methyl-CpG binding domain protein 1	0.027
NIN	ninein (GSK3B interacting protein)	0.026
PARP1	poly (ADP-ribose) polymerase 1	0.026
ANKRD12	ankyrin repeat domain 12	0.025
ASXL1	additional sex combs like 1 (Drosophila)	0.024
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.024
CMIP	c-Maf-inducing protein	0.023
WDR61	WD repeat domain 61	0.022
FANCG	Fanconi anemia, complementation group G	0.022
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.021
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.020
LRP6	low density lipoprotein receptor-related protein 6	0.020
KIAA1370	KIAA1370	0.020
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.020
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.020
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.019
HDAC3	histone deacetylase 3	0.019
ZNF654	zinc finger protein 654	0.018
MRFAP1L1	Morf4 family associated protein 1-like 1	0.018
BICD1	bicaudal D homolog 1 (Drosophila)	0.018
HCFC1	host cell factor C1 (VP16-accessory protein)	0.018
SIN3B	SIN3 homolog B, transcription regulator (yeast)	0.018
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.017
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.017
BIN1	bridging integrator 1	0.017
TRIM23	tripartite motif containing 23	0.016
CCNG2	cyclin G2	0.016
RANBP2	RAN binding protein 2	0.016
SH3KBP1	SH3-domain kinase binding protein 1	0.016
SELENBP1	selenium binding protein 1	0.015
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.015
UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	0.015
CIR1	corepressor interacting with RBPJ, 1	0.015
RFC1	replication factor C (activator 1) 1, 145kDa	0.015
SENP7	SUMO1/sentrin specific peptidase 7	0.014
KIAA1191	KIAA1191	0.014
RUNX1	runt-related transcription factor 1	0.014
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.014
PJA2	praja ring finger 2	0.013
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.013
ZBTB4	zinc finger and BTB domain containing 4	0.013
DCAF7	DDB1 and CUL4 associated factor 7	0.013
SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	0.013
C14orf129	chromosome 14 open reading frame 129	0.013
C5orf54	chromosome 5 open reading frame 54	0.013
MBD2	methyl-CpG binding domain protein 2	0.013
CTBP1	C-terminal binding protein 1	0.013
TMEM44	transmembrane protein 44	0.013
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.013
BEX1	brain expressed, X-linked 1	0.013
THAP8	THAP domain containing 8	0.013
MFAP1	microfibrillar-associated protein 1	0.012
DUSP23	dual specificity phosphatase 23	0.012
RASA2	RAS p21 protein activator 2	0.012
HERPUD2	HERPUD family member 2	0.012
FAM179B	family with sequence similarity 179, member B	0.012
FANCE	Fanconi anemia, complementation group E	0.012
NLRP2	NLR family, pyrin domain containing 2	0.012
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.012
FAM123B	family with sequence similarity 123B	0.012
RNF111	ring finger protein 111	0.011
MTA2	metastasis associated 1 family, member 2	0.011
HIST2H2AC	histone cluster 2, H2ac	0.011
TLR3	toll-like receptor 3	0.011
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.011
FAM110A	family with sequence similarity 110, member A	0.011
XRCC1	X-ray repair complementing defective repair in Chinese hamster cells 1	0.011
DLK1	delta-like 1 homolog (Drosophila)	0.011
EPC2	enhancer of polycomb homolog 2 (Drosophila)	0.011
MDC1	mediator of DNA-damage checkpoint 1	0.011
FBXW8	F-box and WD repeat domain containing 8	0.011
AKAP11	A kinase (PRKA) anchor protein 11	0.011
KDM5B	lysine (K)-specific demethylase 5B	0.011
H3F3B	H3 histone, family 3B (H3.3B)	0.011
ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)	0.010
PCNX	pecanex homolog (Drosophila)	0.010
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.010
PURA	purine-rich element binding protein A	0.010
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.010