IMP

Process View

Homo sapiens

1 genes annotated in human

Multi-species View

regulation of granzyme a production

GO:2000511

Any process that modulates the frequency, rate or extent of granzyme A production.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of granzyme a production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of granzyme a production" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000
IL8	interleukin 8	1.000
CCL5	chemokine (C-C motif) ligand 5	0.996	Human
CCL8	chemokine (C-C motif) ligand 8	0.992	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.991
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.982	Human
CCL4	chemokine (C-C motif) ligand 4	0.981	Human
CCL2	chemokine (C-C motif) ligand 2	0.979	Human
DPP4	dipeptidyl-peptidase 4	0.976
CXCL10	chemokine (C-X-C motif) ligand 10	0.921
IDE	insulin-degrading enzyme	0.893
CXCL2	chemokine (C-X-C motif) ligand 2	0.838
IL1B	interleukin 1, beta	0.806
CXCL11	chemokine (C-X-C motif) ligand 11	0.800
CCL13	chemokine (C-C motif) ligand 13	0.768	Human
IL6	interleukin 6 (interferon, beta 2)	0.698
CCR7	chemokine (C-C motif) receptor 7	0.689
CCL22	chemokine (C-C motif) ligand 22	0.664	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.622
CCL19	chemokine (C-C motif) ligand 19	0.564	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.507
CCL7	chemokine (C-C motif) ligand 7	0.478	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.463
UBD	ubiquitin D	0.421
GNLY	granulysin	0.398
CD83	CD83 molecule	0.379
TNF	tumor necrosis factor	0.377
SELE	selectin E	0.327
IFNG	interferon, gamma	0.290
ARRB1	arrestin, beta 1	0.248
ICAM1	intercellular adhesion molecule 1	0.230
VCAM1	vascular cell adhesion molecule 1	0.230
RGS1	regulator of G-protein signaling 1	0.201
IL2RB	interleukin 2 receptor, beta	0.201
CCR1	chemokine (C-C motif) receptor 1	0.173
SOD2	superoxide dismutase 2, mitochondrial	0.171
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.170
CD40	CD40 molecule, TNF receptor superfamily member 5	0.168
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.152
IL7R	interleukin 7 receptor	0.151
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.145
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.141
DARC	Duffy blood group, chemokine receptor	0.130
FPR3	formyl peptide receptor 3	0.128
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.109
IL1RN	interleukin 1 receptor antagonist	0.104
CCL11	chemokine (C-C motif) ligand 11	0.093	Human
IL21R	interleukin 21 receptor	0.091
CH25H	cholesterol 25-hydroxylase	0.090
CCR4	chemokine (C-C motif) receptor 4	0.088
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.083
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.082
CCL17	chemokine (C-C motif) ligand 17	0.081	Human
LAMP3	lysosomal-associated membrane protein 3	0.075
IL10	interleukin 10	0.069
CCL3	chemokine (C-C motif) ligand 3	0.069	Human
TRAF1	TNF receptor-associated factor 1	0.069
XCL2	chemokine (C motif) ligand 2	0.060	Human
EBI3	Epstein-Barr virus induced 3	0.057
IL2RG	interleukin 2 receptor, gamma	0.057
CCL20	chemokine (C-C motif) ligand 20	0.048	Human
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.048
CXCR3	chemokine (C-X-C motif) receptor 3	0.045
STAT4	signal transducer and activator of transcription 4	0.043
SLAMF7	SLAM family member 7	0.043
IDO1	indoleamine 2,3-dioxygenase 1	0.043
SLAMF8	SLAM family member 8	0.042
CD160	CD160 molecule	0.042
CCR3	chemokine (C-C motif) receptor 3	0.041
IL32	interleukin 32	0.041
IL1A	interleukin 1, alpha	0.040
ADAMDEC1	ADAM-like, decysin 1	0.039
CCL1	chemokine (C-C motif) ligand 1	0.036	Human
CXCL5	chemokine (C-X-C motif) ligand 5	0.034
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.034
CXCR6	chemokine (C-X-C motif) receptor 6	0.034
MSC	musculin	0.033
GPR109B	G protein-coupled receptor 109B	0.033
IL10RA	interleukin 10 receptor, alpha	0.031
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.030
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.030
IL18RAP	interleukin 18 receptor accessory protein	0.030
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.028
CCL23	chemokine (C-C motif) ligand 23	0.028	Human
BCL2A1	BCL2-related protein A1	0.027
XCL1	chemokine (C motif) ligand 1	0.026
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.025
RGS16	regulator of G-protein signaling 16	0.025
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.024
CD69	CD69 molecule	0.024
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.023
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.023
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.022
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.022
GZMK	granzyme K (granzyme 3; tryptase II)	0.022
CCRL2	chemokine (C-C motif) receptor-like 2	0.021
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.021
IL2RA	interleukin 2 receptor, alpha	0.021
CSF1	colony stimulating factor 1 (macrophage)	0.021
APOC1	apolipoprotein C-I	0.021
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.020
IRF4	interferon regulatory factor 4	0.018
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.018
IL13	interleukin 13	0.017
CD209	CD209 molecule	0.016
CD1B	CD1b molecule	0.016
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.016
BATF	basic leucine zipper transcription factor, ATF-like	0.016
DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A	0.016
IL1R1	interleukin 1 receptor, type I	0.016
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.015
CD80	CD80 molecule	0.014
LAG3	lymphocyte-activation gene 3	0.014
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.014
CCBP2	chemokine binding protein 2	0.014
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.013
BDKRB1	bradykinin receptor B1	0.013
PDPN	podoplanin	0.013
IL4I1	interleukin 4 induced 1	0.013
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.012
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.012
SRGN	serglycin	0.012
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.012
BIRC3	baculoviral IAP repeat containing 3	0.012
IL1F5	interleukin 1 family, member 5 (delta)	0.012
PLEK	pleckstrin	0.011
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.011
EGR2	early growth response 2	0.011
RUNX3	runt-related transcription factor 3	0.011
PRDM1	PR domain containing 1, with ZNF domain	0.011
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.011
PTGES	prostaglandin E synthase	0.011
IL7	interleukin 7	0.011
IL5	interleukin 5 (colony-stimulating factor, eosinophil)	0.010
IL1F9	interleukin 1 family, member 9	0.010
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.010
LRRC32	leucine rich repeat containing 32	0.010
GPR84	G protein-coupled receptor 84	0.010
IL4	interleukin 4	0.010
DUSP2	dual specificity phosphatase 2	0.010
ZC3H12A	zinc finger CCCH-type containing 12A	0.010