IMP

Process View

Homo sapiens

23 genes annotated in human

regulation of mrna stability

Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of mrna stability"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of mrna stability" (in gray)

Name	Description	Probability	Func Analog Organism
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.996	Mouse Rat
TOB1	transducer of ERBB2, 1	0.920
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.889
MAPK14	mitogen-activated protein kinase 14	0.848
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.538	Mouse
E2F1	E2F transcription factor 1	0.535
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.482
RB1	retinoblastoma 1	0.481
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.388
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.330
ILF3	interleukin enhancer binding factor 3, 90kDa	0.321
SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	0.272
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.226
SFPQ	splicing factor proline/glutamine-rich	0.203
RBL2	retinoblastoma-like 2 (p130)	0.183
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.182
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.130
HNRNPR	heterogeneous nuclear ribonucleoprotein R	0.124	Human
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.106
TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	0.105
ILF2	interleukin enhancer binding factor 2, 45kDa	0.098
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.086
HSF1	heat shock transcription factor 1	0.080
RBMX	RNA binding motif protein, X-linked	0.077
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.076
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.073
NRP1	neuropilin 1	0.068
PRMT1	protein arginine methyltransferase 1	0.065
IRAK2	interleukin-1 receptor-associated kinase 2	0.064
TARDBP	TAR DNA binding protein	0.064
TFDP1	transcription factor Dp-1	0.058
PTBP1	polypyrimidine tract binding protein 1	0.058
TLR4	toll-like receptor 4	0.054
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.054
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.053
E2F4	E2F transcription factor 4, p107/p130-binding	0.053	Human
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.050
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.048
CUL1	cullin 1	0.044
E2F3	E2F transcription factor 3	0.044	Human
SF1	splicing factor 1	0.041
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.039
TOP1	topoisomerase (DNA) I	0.035
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.032
HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	0.031
BTG2	BTG family, member 2	0.030
DAZL	deleted in azoospermia-like	0.030
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.030
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.029
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.027
MYD88	myeloid differentiation primary response gene (88)	0.027
QKI	quaking homolog, KH domain RNA binding (mouse)	0.026	Zebrafish Mouse
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.026
WDR26	WD repeat domain 26	0.025
CUL3	cullin 3	0.025
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.024
MAPK6	mitogen-activated protein kinase 6	0.024
IRAK4	interleukin-1 receptor-associated kinase 4	0.024
CUX1	cut-like homeobox 1	0.024
MATR3	matrin 3	0.023
NONO	non-POU domain containing, octamer-binding	0.023
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.022
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.022
STC2	stanniocalcin 2	0.021
RBM12	RNA binding motif protein 12	0.021
PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)	0.021
HMGA2	high mobility group AT-hook 2	0.019
YBX1	Y box binding protein 1	0.019
HABP4	hyaluronan binding protein 4	0.019
IRAK1	interleukin-1 receptor-associated kinase 1	0.019
MYBL2	v-myb myeloblastosis viral oncogene homolog (avian)-like 2	0.019
PURA	purine-rich element binding protein A	0.018
HDAC11	histone deacetylase 11	0.018
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.017
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.017
CNOT2	CCR4-NOT transcription complex, subunit 2	0.017
PHC2	polyhomeotic homolog 2 (Drosophila)	0.017
HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	0.017
NFIL3	nuclear factor, interleukin 3 regulated	0.016
CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	0.016
FBXO33	F-box protein 33	0.016
GSK3A	glycogen synthase kinase 3 alpha	0.015
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.015
MAST1	microtubule associated serine/threonine kinase 1	0.014
CUL4A	cullin 4A	0.014
AHR	aryl hydrocarbon receptor	0.014
AEBP2	AE binding protein 2	0.013
NUP98	nucleoporin 98kDa	0.013
RBBP4	retinoblastoma binding protein 4	0.013
LIN9	lin-9 homolog (C. elegans)	0.013
E2F2	E2F transcription factor 2	0.013	Human
NCOA6	nuclear receptor coactivator 6	0.013
SF3B4	splicing factor 3b, subunit 4, 49kDa	0.013
PURB	purine-rich element binding protein B	0.012
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.012
SRSF9	serine/arginine-rich splicing factor 9	0.012
KAT2B	K(lysine) acetyltransferase 2B	0.012
FUS	fused in sarcoma	0.012
CTCF	CCCTC-binding factor (zinc finger protein)	0.012
HDAC1	histone deacetylase 1	0.012
LIN54	lin-54 homolog (C. elegans)	0.012
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.012
C12orf41	chromosome 12 open reading frame 41	0.011
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.011
TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.011	Yeast
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.011
PUM2	pumilio homolog 2 (Drosophila)	0.010
RBM41	RNA binding motif protein 41	0.010