IMP

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Mus musculus

2 genes annotated in mouse

leukotriene production involved in inflammatory response

The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "leukotriene production involved in inflammatory response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "leukotriene production involved in inflammatory response" (in gray)

Name	Description	Probability	Func Analog Organism
Alox5	arachidonate 5-lipoxygenase	0.941
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.804
Orai1	ORAI calcium release-activated calcium modulator 1	0.632
Ptges	prostaglandin E synthase	0.565
Tyrobp	TYRO protein tyrosine kinase binding protein	0.435
Ccl6	chemokine (C-C motif) ligand 6	0.133
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.125
Col17a1	collagen, type XVII, alpha 1	0.112
Krt15	keratin 15	0.092
Retn	resistin	0.091
Cdsn	corneodesmosin	0.088
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.078
Asprv1	aspartic peptidase, retroviral-like 1	0.073
Pf4	platelet factor 4	0.070
Htra3	HtrA serine peptidase 3	0.067
Dmkn	dermokine	0.066
Krtdap	keratinocyte differentiation associated protein	0.058
Cfd	complement factor D (adipsin)	0.056
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.056
Tmem40	transmembrane protein 40	0.056
Tnni2	troponin I, skeletal, fast 2	0.055
Cma1	chymase 1, mast cell	0.051
Lefty1	left right determination factor 1	0.049
Padi4	peptidyl arginine deiminase, type IV	0.048
Rab25	RAB25, member RAS oncogene family	0.045
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.044
Krt13	keratin 13	0.044
Gp9	glycoprotein 9 (platelet)	0.044
Fcna	ficolin A	0.041
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.041
Anxa8	annexin A8	0.040
Alox15	arachidonate 15-lipoxygenase	0.040	Mouse
Sftpb	surfactant associated protein B	0.040
Ppl	periplakin	0.038
S100a4	S100 calcium binding protein A4	0.037
Expi	extracellular proteinase inhibitor	0.036
Slurp1	secreted Ly6/Plaur domain containing 1	0.035
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.035
Chad	chondroadherin	0.034
Nrtn	neurturin	0.033
Ch25h	cholesterol 25-hydroxylase	0.033
Fes	feline sarcoma oncogene	0.033
Folr2	folate receptor 2 (fetal)	0.032
Ltf	lactotransferrin	0.032
Cidec	cell death-inducing DFFA-like effector c	0.031
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.031
Treml1	triggering receptor expressed on myeloid cells-like 1	0.031
Gna15	guanine nucleotide binding protein, alpha 15	0.031
Adig	adipogenin	0.031
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.030
Cbr2	carbonyl reductase 2	0.030
Msln	mesothelin	0.029
Fxyd2	FXYD domain-containing ion transport regulator 2	0.028
Lgals7	lectin, galactose binding, soluble 7	0.027
Clic3	chloride intracellular channel 3	0.027
Cd68	CD68 antigen	0.027
Fxyd5	FXYD domain-containing ion transport regulator 5	0.027
Lyl1	lymphoblastomic leukemia 1	0.026
C5ar1	complement component 5a receptor 1	0.026
Apoc1	apolipoprotein C-I	0.025
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.025
Ccl11	chemokine (C-C motif) ligand 11	0.024
Mybph	myosin binding protein H	0.023
Slpi	secretory leukocyte peptidase inhibitor	0.023
Fcgr3	Fc receptor, IgG, low affinity III	0.022
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.022
Irs3	insulin receptor substrate 3	0.022
Cd14	CD14 antigen	0.022
Plin4	perilipin 4	0.022
Adora2b	adenosine A2b receptor	0.022
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.021
Gata1	GATA binding protein 1	0.021
Timp1	tissue inhibitor of metalloproteinase 1	0.021
Il1r2	interleukin 1 receptor, type II	0.021
Adam8	a disintegrin and metallopeptidase domain 8	0.021
Calm4	calmodulin 4	0.021
Nrap	nebulin-related anchoring protein	0.020
Il34	interleukin 34	0.020
S100a6	S100 calcium binding protein A6 (calcyclin)	0.019
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.019
Ctgf	connective tissue growth factor	0.019
Aoc3	amine oxidase, copper containing 3	0.019
F13a1	coagulation factor XIII, A1 subunit	0.019
Ccl24	chemokine (C-C motif) ligand 24	0.018
Slfn4	schlafen 4	0.018
Ckmt2	creatine kinase, mitochondrial 2	0.018
Ccl2	chemokine (C-C motif) ligand 2	0.018
Clec3b	C-type lectin domain family 3, member b	0.018
Sfrp4	secreted frizzled-related protein 4	0.018
Csf1r	colony stimulating factor 1 receptor	0.018
Trim47	tripartite motif-containing 47	0.017
C1qb	complement component 1, q subcomponent, beta polypeptide	0.017
Tnfrsf17	tumor necrosis factor receptor superfamily, member 17	0.017
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.017
Epor	erythropoietin receptor	0.017
Ccl9	chemokine (C-C motif) ligand 9	0.017
Pdcd1	programmed cell death 1	0.017
Pi16	peptidase inhibitor 16	0.016
Ier3	immediate early response 3	0.016
Foxd2	forkhead box D2	0.016
Krt4	keratin 4	0.016
Gpr133	G protein-coupled receptor 133	0.016
Endou	endonuclease, polyU-specific	0.016
Ccl7	chemokine (C-C motif) ligand 7	0.016
Emilin2	elastin microfibril interfacer 2	0.016
Aldh3a1	aldehyde dehydrogenase family 3, subfamily A1	0.016
Elane	elastase, neutrophil expressed	0.016
Atf3	activating transcription factor 3	0.015
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.015
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.015
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.015
Bik	BCL2-interacting killer	0.015
Krt5	keratin 5	0.015
Lst1	leukocyte specific transcript 1	0.015
Zbtb7c	zinc finger and BTB domain containing 7C	0.015
Tnnt3	troponin T3, skeletal, fast	0.015
Ptgir	prostaglandin I receptor (IP)	0.015
Ifitm6	interferon induced transmembrane protein 6	0.015
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.014
Mgmt	O-6-methylguanine-DNA methyltransferase	0.014
Cyr61	cysteine rich protein 61	0.014
Apobr	apolipoprotein B receptor	0.014
Lcn2	lipocalin 2	0.014
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.014
Actn3	actinin alpha 3	0.014
Thbs1	thrombospondin 1	0.014
Wisp2	WNT1 inducible signaling pathway protein 2	0.013
Lgals3	lectin, galactose binding, soluble 3	0.013
Lyz1	lysozyme 1	0.013
Tspo2	translocator protein 2	0.013
Itga2b	integrin alpha 2b	0.013
Clec10a	C-type lectin domain family 10, member A	0.013
Sftpd	surfactant associated protein D	0.013
Gdf15	growth differentiation factor 15	0.013
Cmklr1	chemokine-like receptor 1	0.013
Gp1ba	glycoprotein 1b, alpha polypeptide	0.013
Clec4n	C-type lectin domain family 4, member n	0.013
Cel	carboxyl ester lipase	0.013
Xirp1	xin actin-binding repeat containing 1	0.012
Mall	mal, T-cell differentiation protein-like	0.012
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.012
Psca	prostate stem cell antigen	0.012
Myoz1	myozenin 1	0.012
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.012
Padi1	peptidyl arginine deiminase, type I	0.012
Matn4	matrilin 4	0.012
Selp	selectin, platelet	0.012
Psapl1	prosaposin-like 1	0.012
Ctla2b	cytotoxic T lymphocyte-associated protein 2 beta	0.012
C1qc	complement component 1, q subcomponent, C chain	0.012
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.012
Emp3	epithelial membrane protein 3	0.012
Cib2	calcium and integrin binding family member 2	0.012
Camp	cathelicidin antimicrobial peptide	0.012
Ccl8	chemokine (C-C motif) ligand 8	0.011
Ear5	eosinophil-associated, ribonuclease A family, member 5	0.011
Hspb2	heat shock protein 2	0.011
AF251705	cDNA sequence AF251705	0.011
Lgr6	leucine-rich repeat-containing G protein-coupled receptor 6	0.011
C3ar1	complement component 3a receptor 1	0.011
Ccl12	chemokine (C-C motif) ligand 12	0.011
Ly6d	lymphocyte antigen 6 complex, locus D	0.011
Nrgn	neurogranin	0.011
Tnxb	tenascin XB	0.011
Aif1	allograft inflammatory factor 1	0.011
Hbegf	heparin-binding EGF-like growth factor	0.011
Pvalb	parvalbumin	0.011
Lox	lysyl oxidase	0.011
Prtn3	proteinase 3	0.010
Mybpc3	myosin binding protein C, cardiac	0.010
Pitx3	paired-like homeodomain transcription factor 3	0.010
Adm	adrenomedullin	0.010
Reg3g	regenerating islet-derived 3 gamma	0.010
Il1rn	interleukin 1 receptor antagonist	0.010
Hal	histidine ammonia lyase	0.010
Fcgbp	Fc fragment of IgG binding protein	0.010