IMP
Process View
cholesterol esterification
A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cholesterol esterification"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Apoe | apolipoprotein E | 0.999 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.990 | Human | |
| Lepr | leptin receptor | 0.988 | ||
| Ldlr | low density lipoprotein receptor | 0.981 | ||
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.970 | Human | |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.882 | ||
| Apoa1 | apolipoprotein A-I | 0.860 | Human Mouse | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.854 | ||
| Ren1 | renin 1 structural | 0.726 | ||
| Lyz2 | lysozyme 2 | 0.682 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.659 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.509 | ||
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.409 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.351 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.349 | ||
| Npc1 | Niemann Pick type C1 | 0.310 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.293 | ||
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.266 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.252 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.249 | ||
| Vegfa | vascular endothelial growth factor A | 0.192 | ||
| Aldob | aldolase B, fructose-bisphosphate | 0.164 | ||
| Vdr | vitamin D receptor | 0.159 | ||
| Gcgr | glucagon receptor | 0.144 | ||
| Agtrap | angiotensin II, type I receptor-associated protein | 0.101 | ||
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.100 | ||
| Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.094 | ||
| Lcat | lecithin cholesterol acyltransferase | 0.082 | Human | |
| Abhd5 | abhydrolase domain containing 5 | 0.081 | ||
| Lpin1 | lipin 1 | 0.081 | ||
| Apob | apolipoprotein B | 0.079 | ||
| F2 | coagulation factor II | 0.077 | ||
| C3 | complement component 3 | 0.069 | ||
| Apoc3 | apolipoprotein C-III | 0.068 | ||
| Klf15 | Kruppel-like factor 15 | 0.068 | ||
| Rxra | retinoid X receptor alpha | 0.068 | ||
| Plg | plasminogen | 0.063 | ||
| Scarb1 | scavenger receptor class B, member 1 | 0.063 | ||
| Ahsg | alpha-2-HS-glycoprotein | 0.062 | ||
| Hr | hairless | 0.059 | ||
| Prnp | prion protein | 0.057 | ||
| Apoa2 | apolipoprotein A-II | 0.052 | ||
| Vav2 | vav 2 oncogene | 0.049 | ||
| Nr1h3 | nuclear receptor subfamily 1, group H, member 3 | 0.048 | ||
| Mt2 | metallothionein 2 | 0.045 | ||
| Fgg | fibrinogen gamma chain | 0.044 | ||
| Ambp | alpha 1 microglobulin/bikunin | 0.044 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.043 | ||
| Hsd11b1 | hydroxysteroid 11-beta dehydrogenase 1 | 0.042 | ||
| Ghr | growth hormone receptor | 0.041 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.040 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.035 | ||
| Nr3c2 | nuclear receptor subfamily 3, group C, member 2 | 0.033 | ||
| Apom | apolipoprotein M | 0.032 | ||
| Apoc4 | apolipoprotein C-IV | 0.031 | ||
| Serpinf2 | serine (or cysteine) peptidase inhibitor, clade F, member 2 | 0.028 | ||
| Fgb | fibrinogen beta chain | 0.027 | ||
| Apoc1 | apolipoprotein C-I | 0.027 | ||
| Ttr | transthyretin | 0.026 | ||
| Spp1 | secreted phosphoprotein 1 | 0.026 | ||
| Gc | group specific component | 0.026 | ||
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.026 | ||
| Pltp | phospholipid transfer protein | 0.025 | ||
| Soat1 | sterol O-acyltransferase 1 | 0.024 | ||
| Fasn | fatty acid synthase | 0.024 | ||
| Angptl3 | angiopoietin-like 3 | 0.024 | ||
| Cyp2d10 | cytochrome P450, family 2, subfamily d, polypeptide 10 | 0.022 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.021 | ||
| Mt1 | metallothionein 1 | 0.020 | ||
| F12 | coagulation factor XII (Hageman factor) | 0.020 | ||
| Gjb1 | gap junction protein, beta 1 | 0.019 | ||
| Lpl | lipoprotein lipase | 0.018 | ||
| Gulo | gulonolactone (L-) oxidase | 0.018 | ||
| Cd59a | CD59a antigen | 0.017 | ||
| Apoa5 | apolipoprotein A-V | 0.017 | Mouse | |
| Pcx | pyruvate carboxylase | 0.017 | ||
| Ppara | peroxisome proliferator activated receptor alpha | 0.017 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.017 | ||
| Gnmt | glycine N-methyltransferase | 0.017 | ||
| Cbs | cystathionine beta-synthase | 0.017 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.016 | ||
| Abcg1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.016 | ||
| Sdsl | serine dehydratase-like | 0.016 | ||
| Cdhr5 | cadherin-related family member 5 | 0.016 | ||
| Kit | kit oncogene | 0.016 | ||
| Mpv17 | MpV17 mitochondrial inner membrane protein | 0.015 | ||
| Sec14l2 | SEC14-like 2 (S. cerevisiae) | 0.015 | ||
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.015 | ||
| Cyp2d26 | cytochrome P450, family 2, subfamily d, polypeptide 26 | 0.015 | ||
| Idua | iduronidase, alpha-L- | 0.015 | ||
| Serpind1 | serine (or cysteine) peptidase inhibitor, clade D, member 1 | 0.015 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.015 | ||
| Fbn1 | fibrillin 1 | 0.015 | ||
| Hpd | 4-hydroxyphenylpyruvic acid dioxygenase | 0.014 | ||
| Itih3 | inter-alpha trypsin inhibitor, heavy chain 3 | 0.014 | ||
| Abcg8 | ATP-binding cassette, sub-family G (WHITE), member 8 | 0.014 | ||
| Slc6a13 | solute carrier family 6 (neurotransmitter transporter, GABA), member 13 | 0.014 | ||
| Mmd2 | monocyte to macrophage differentiation-associated 2 | 0.013 | ||
| Lmf1 | lipase maturation factor 1 | 0.013 | ||
| Hpn | hepsin | 0.013 | ||
| Slc1a2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 0.013 | ||
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.013 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.013 | ||
| C8b | complement component 8, beta polypeptide | 0.013 | ||
| Hpx | hemopexin | 0.013 | ||
| Dmgdh | dimethylglycine dehydrogenase precursor | 0.012 | ||
| Serpinc1 | serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 | 0.012 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.012 | ||
| Psap | prosaposin | 0.012 | ||
| Hnf4a | hepatic nuclear factor 4, alpha | 0.012 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.012 | ||
| Wnk4 | WNK lysine deficient protein kinase 4 | 0.012 | ||
| Pah | phenylalanine hydroxylase | 0.012 | ||
| Fga | fibrinogen alpha chain | 0.012 | ||
| Cav1 | caveolin 1, caveolae protein | 0.011 | ||
| Add2 | adducin 2 (beta) | 0.011 | ||
| Slc38a3 | solute carrier family 38, member 3 | 0.011 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.011 | ||
| Slc12a1 | solute carrier family 12, member 1 | 0.011 | ||
| Tlr2 | toll-like receptor 2 | 0.011 | ||
| Cideb | cell death-inducing DNA fragmentation factor, alpha subunit-like effector B | 0.011 | ||
| Abcg5 | ATP-binding cassette, sub-family G (WHITE), member 5 | 0.011 | ||
| Tlr4 | toll-like receptor 4 | 0.010 | ||
| Cd36 | CD36 antigen | 0.010 | ||
| Slc27a2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.010 | ||
| Mus81 | MUS81 endonuclease homolog (yeast) | 0.010 | ||
| Aspdh | aspartate dehydrogenase domain containing | 0.010 |