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Mus musculus

16 genes annotated in mouse

Multi-species View

regulation of water loss via skin

GO:0033561

A process that modulates the rate or extent of water loss from an organism via the skin.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of water loss via skin"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of water loss via skin" (in gray)

Name	Description	Probability	Func Analog Organism
Trp63	transformation related protein 63	0.913
Krt17	keratin 17	0.606
Irf6	interferon regulatory factor 6	0.553
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.517
Krt8	keratin 8	0.457	Mouse
Cdcp1	CUB domain containing protein 1	0.426
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.394	Mouse
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.301	Mouse
Cela3b	chymotrypsin-like elastase family, member 3B	0.292	Mouse
Krt6a	keratin 6A	0.243	Mouse
Tgm3	transglutaminase 3, E polypeptide	0.223
Krt19	keratin 19	0.197
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.191
Hr	hairless	0.176
Rpgrip1l	Rpgrip1-like	0.170
Psapl1	prosaposin-like 1	0.158
Foxn1	forkhead box N1	0.156
Krt5	keratin 5	0.144	Mouse
Sprr1a	small proline-rich protein 1A	0.142
Dsg2	desmoglein 2	0.138
Cel	carboxyl ester lipase	0.127
Rdh8	retinol dehydrogenase 8	0.127
Krt13	keratin 13	0.124
Krtap3-1	keratin associated protein 3-1	0.124
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.112	Mouse
Krt33b	keratin 33B	0.109
Krt18	keratin 18	0.100
Crb3	crumbs homolog 3 (Drosophila)	0.100
Il1f5	interleukin 1 family, member 5 (delta)	0.099
Krtap8-1	keratin associated protein 8-1	0.094
Trim29	tripartite motif-containing 29	0.094
Rnase1	ribonuclease, RNase A family, 1 (pancreatic)	0.094
Krt31	keratin 31	0.091
Cyp26c1	cytochrome P450, family 26, subfamily c, polypeptide 1	0.091	Mouse
Trpv5	transient receptor potential cation channel, subfamily V, member 5	0.090
Krt14	keratin 14	0.085
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.084
Try5	trypsin 5	0.083
Asprv1	aspartic peptidase, retroviral-like 1	0.081
Ppl	periplakin	0.081
Rab25	RAB25, member RAS oncogene family	0.077
Casp14	caspase 14	0.076
Cldn3	claudin 3	0.076	Mouse
Lrrk2	leucine-rich repeat kinase 2	0.074
Tjp3	tight junction protein 3	0.072
Slurp1	secreted Ly6/Plaur domain containing 1	0.071
Krt72-ps	keratin 72, pseudogene	0.071	Mouse
Dlx3	distal-less homeobox 3	0.069
Cldn7	claudin 7	0.068	Mouse
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.067	Mouse
Cldn4	claudin 4	0.065	Mouse
Dsc3	desmocollin 3	0.064	Mouse
Tmprss2	transmembrane protease, serine 2	0.062
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.059
Krt1	keratin 1	0.059
Krt33a	keratin 33A	0.059
Sprr1b	small proline-rich protein 1B	0.058
Krt71	keratin 71	0.055	Mouse
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.053
Wfdc2	WAP four-disulfide core domain 2	0.053
Krt85	keratin 85	0.053
Cldn6	claudin 6	0.050	Mouse
Prss2	protease, serine, 2	0.050
Krt32	keratin 32	0.049
Krt77	keratin 77	0.048	Mouse
Slc46a2	solute carrier family 46, member 2	0.047
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.047
Tmem30b	transmembrane protein 30B	0.046
Lgals7	lectin, galactose binding, soluble 7	0.045
Mdm2	transformed mouse 3T3 cell double minute 2	0.044
Cuzd1	CUB and zona pellucida-like domains 1	0.044
Wnt10a	wingless related MMTV integration site 10a	0.043
Dsc1	desmocollin 1	0.042	Mouse
Sebox	SEBOX homeobox	0.042
Epcam	epithelial cell adhesion molecule	0.039
Elf3	E74-like factor 3	0.038
Clps	colipase, pancreatic	0.037
Alox12e	arachidonate lipoxygenase, epidermal	0.036	Mouse
Upk3a	uroplakin 3A	0.036
Krt15	keratin 15	0.036
Prss8	protease, serine, 8 (prostasin)	0.036
2310002J15Rik	RIKEN cDNA 2310002J15 gene	0.035
Spint1	serine protease inhibitor, Kunitz type 1	0.035
Pkp1	plakophilin 1	0.035
Mybph	myosin binding protein H	0.034
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.034
Ins2	insulin II	0.034
Duoxa1	dual oxidase maturation factor 1	0.033
Dmbt1	deleted in malignant brain tumors 1	0.033
Npc1	Niemann Pick type C1	0.033
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.032
Trp73	transformation related protein 73	0.031	Mouse
Lamc2	laminin, gamma 2	0.031
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.031
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.030
S100a14	S100 calcium binding protein A14	0.030
Klk6	kallikrein related-peptidase 6	0.030
Cpa1	carboxypeptidase A1	0.029
Reg2	regenerating islet-derived 2	0.029
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.029
Prg3	proteoglycan 3	0.028
Sycn	syncollin	0.028
Slc23a3	solute carrier family 23 (nucleobase transporters), member 3	0.028
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.028
Lad1	ladinin	0.028
Apoa1	apolipoprotein A-I	0.028
Dcc	deleted in colorectal carcinoma	0.027
Krt86	keratin 86	0.027	Mouse
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.027
Pten	phosphatase and tensin homolog	0.027
Sprr3	small proline-rich protein 3	0.027
Tcfap2c	transcription factor AP-2, gamma	0.026
Tff1	trefoil factor 1	0.026
Krt4	keratin 4	0.026	Mouse
Ocln	occludin	0.026
Tjp1	tight junction protein 1	0.025
Dsg4	desmoglein 4	0.025
Padi3	peptidyl arginine deiminase, type III	0.025
Gm13011	predicted gene 13011	0.025	Mouse
Pthlh	parathyroid hormone-like peptide	0.025
Srebf2	sterol regulatory element binding factor 2	0.024
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.024
Calm4	calmodulin 4	0.023
Dsp	desmoplakin	0.023
Ppy	pancreatic polypeptide	0.023
Krt84	keratin 84	0.023	Mouse
Tff3	trefoil factor 3, intestinal	0.023
Ptges	prostaglandin E synthase	0.023
Th	tyrosine hydroxylase	0.022
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.022	Mouse
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.022
Serpinb7	serine (or cysteine) peptidase inhibitor, clade B, member 7	0.022
Cela2a	chymotrypsin-like elastase family, member 2A	0.022
Shank3	SH3/ankyrin domain gene 3	0.022
2310014L17Rik	RIKEN cDNA 2310014L17 gene	0.021
Ins1	insulin I	0.021
Mt4	metallothionein 4	0.021
Slc7a9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.021
Defb1	defensin beta 1	0.021
Mogat2	monoacylglycerol O-acyltransferase 2	0.021
Krt2	keratin 2	0.021	Mouse
Fxyd3	FXYD domain-containing ion transport regulator 3	0.021
Foxq1	forkhead box Q1	0.021
Gm10334	predicted gene 10334	0.021
Mfi2	antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5	0.021
Tacstd2	tumor-associated calcium signal transducer 2	0.021
Bad	BCL2-associated agonist of cell death	0.021
Fam83h	family with sequence similarity 83, member H	0.020
Ripk4	receptor-interacting serine-threonine kinase 4	0.020
Foxb2	forkhead box B2	0.020
Gja3	gap junction protein, alpha 3	0.020
Krt36	keratin 36	0.020
Fut1	fucosyltransferase 1	0.020
Tjp2	tight junction protein 2	0.020
Onecut1	one cut domain, family member 1	0.020
Ggt1	gamma-glutamyltransferase 1	0.020
Zfp185	zinc finger protein 185	0.019
Egfr	epidermal growth factor receptor	0.019
Il12rb2	interleukin 12 receptor, beta 2	0.019
S100a3	S100 calcium binding protein A3	0.019
Tulp1	tubby like protein 1	0.019
Klk1b11	kallikrein 1-related peptidase b11	0.019
Tcfap2b	transcription factor AP-2 beta	0.019
Defa-rs12	defensin, alpha, related sequence 12	0.019
Esrp1	epithelial splicing regulatory protein 1	0.019
Syt8	synaptotagmin VIII	0.018
Sftpd	surfactant associated protein D	0.018
Aloxe3	arachidonate lipoxygenase 3	0.018
Ptprb	protein tyrosine phosphatase, receptor type, B	0.018
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.018
Krtdap	keratinocyte differentiation associated protein	0.018
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.018
Nfib	nuclear factor I/B	0.017
Gjb4	gap junction protein, beta 4	0.017
Gjd2	gap junction protein, delta 2	0.017
Hoxb2	homeobox B2	0.017
Epha2	Eph receptor A2	0.017
Aqp2	aquaporin 2	0.017
Gpr87	G protein-coupled receptor 87	0.017
Ctrb1	chymotrypsinogen B1	0.017	Mouse
Lce1b	late cornified envelope 1B	0.017
Krt42	keratin 42	0.017
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.017
Mpzl2	myelin protein zero-like 2	0.017
Mapk13	mitogen-activated protein kinase 13	0.016
Cyp2b19	cytochrome P450, family 2, subfamily b, polypeptide 19	0.016
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.016
Msgn1	mesogenin 1	0.016
Smr3a	submaxillary gland androgen regulated protein 3A	0.016
Endou	endonuclease, polyU-specific	0.016
Ptch2	patched homolog 2	0.016
Abcg5	ATP-binding cassette, sub-family G (WHITE), member 5	0.016
Pou3f3	POU domain, class 3, transcription factor 3	0.016
Itgb4	integrin beta 4	0.016
Dmkn	dermokine	0.016
Krt27	keratin 27	0.016
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.016
Tmem54	transmembrane protein 54	0.016
Eng	endoglin	0.016
Reg1	regenerating islet-derived 1	0.016
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.015	Mouse
Ntn1	netrin 1	0.015
Cldn8	claudin 8	0.015
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.015
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.015	Mouse
Prss3	protease, serine, 3	0.015
Onecut2	one cut domain, family member 2	0.015
Ctrl	chymotrypsin-like	0.015	Mouse
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.015
Krt12	keratin 12	0.014
9130017N09Rik	RIKEN cDNA 9130017N09 gene	0.014
Ehf	ets homologous factor	0.014
Phlda2	pleckstrin homology-like domain, family A, member 2	0.014
Coch	coagulation factor C homolog (Limulus polyphemus)	0.014
Foxd1	forkhead box D1	0.014
Jph2	junctophilin 2	0.014
Tmprss13	transmembrane protease, serine 13	0.014
Wnk4	WNK lysine deficient protein kinase 4	0.014
Crct1	cysteine-rich C-terminal 1	0.014
Irx4	Iroquois related homeobox 4 (Drosophila)	0.014
L1cam	L1 cell adhesion molecule	0.014
Trpv6	transient receptor potential cation channel, subfamily V, member 6	0.014
Krtap14	keratin associated protein 14	0.014
Slc5a11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.014
Scnn1b	sodium channel, nonvoltage-gated 1 beta	0.013
Mpdz	multiple PDZ domain protein	0.013
Klk1	kallikrein 1	0.013
Aldh3a1	aldehyde dehydrogenase family 3, subfamily A1	0.013
Tubb4	tubulin, beta 4	0.013
Try10	trypsin 10	0.013
Ptf1a	pancreas specific transcription factor, 1a	0.013
Lce1a2	late cornified envelope 1A2	0.013
Klk7	kallikrein related-peptidase 7 (chymotryptic, stratum corneum)	0.013
Oxt	oxytocin	0.013
Cga	glycoprotein hormones, alpha subunit	0.013
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.013
Bsnd	Bartter syndrome, infantile, with sensorineural deafness (Barttin)	0.013
Ppara	peroxisome proliferator activated receptor alpha	0.013
Lce1a1	late cornified envelope 1A1	0.013
F11r	F11 receptor	0.013
Gjb5	gap junction protein, beta 5	0.013
Fcgbp	Fc fragment of IgG binding protein	0.012
Esam	endothelial cell-specific adhesion molecule	0.012
Bhlha15	basic helix-loop-helix family, member a15	0.012
Mal	myelin and lymphocyte protein, T-cell differentiation protein	0.012
Lce1h	late cornified envelope 1H	0.012
Muc1	mucin 1, transmembrane	0.012
Krt16	keratin 16	0.012
Galnt3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3	0.012
Dsc2	desmocollin 2	0.012	Mouse
Gm2663	predicted gene 2663	0.012
Tg	thyroglobulin	0.012
Ivl	involucrin	0.012
Fgf5	fibroblast growth factor 5	0.012
Expi	extracellular proteinase inhibitor	0.012
Plekhg6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.012
Fam83f	family with sequence similarity 83, member F	0.012
Bnc1	basonuclin 1	0.012
Reg3b	regenerating islet-derived 3 beta	0.012
Eda	ectodysplasin-A	0.012
Lama5	laminin, alpha 5	0.011
Fxyd4	FXYD domain-containing ion transport regulator 4	0.011
Igfbp2	insulin-like growth factor binding protein 2	0.011
Foxa1	forkhead box A1	0.011
Dct	dopachrome tautomerase	0.011
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.011
Zfp92	zinc finger protein 92	0.011
Lypd3	Ly6/Plaur domain containing 3	0.011
Sult2b1	sulfotransferase family, cytosolic, 2B, member 1	0.011
Kit	kit oncogene	0.011
Tyr	tyrosinase	0.011
Ly6g6d	lymphocyte antigen 6 complex, locus G6D	0.011
Fshb	follicle stimulating hormone beta	0.011
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.011
Esyt3	extended synaptotagmin-like protein 3	0.011
Hspa8	heat shock protein 8	0.011
Gucy2c	guanylate cyclase 2c	0.011
Cdx2	caudal type homeobox 2	0.011
Aatk	apoptosis-associated tyrosine kinase	0.011
Krt34	keratin 34	0.011
Cnr1	cannabinoid receptor 1 (brain)	0.011
Clic3	chloride intracellular channel 3	0.011
Cbs	cystathionine beta-synthase	0.011
Cpz	carboxypeptidase Z	0.011
Marveld3	MARVEL (membrane-associating) domain containing 3	0.011
Cdh6	cadherin 6	0.010
Pcdh12	protocadherin 12	0.010
Amelx	amelogenin X chromosome	0.010
Sntb1	syntrophin, basic 1	0.010
Defb6	defensin beta 6	0.010
Tcl1b4	T-cell leukemia/lymphoma 1B, 4	0.010
Gprc5d	G protein-coupled receptor, family C, group 5, member D	0.010
Ihh	Indian hedgehog	0.010
Wnt16	wingless-related MMTV integration site 16	0.010
Krtap5-2	keratin associated protein 5-2	0.010
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.010
2310042E22Rik	RIKEN cDNA 2310042E22 gene	0.010
Tchh	trichohyalin	0.010
Cldn2	claudin 2	0.010	Mouse
Guca2b	guanylate cyclase activator 2b (retina)	0.010