IMP

Process View

Mus musculus

2 genes annotated in mouse

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glutamate biosynthetic process

GO:0006537

The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glutamate biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "glutamate biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Immt	inner membrane protein, mitochondrial	0.704
Mdh1	malate dehydrogenase 1, NAD (soluble)	0.551
Dlg4	discs, large homolog 4 (Drosophila)	0.219
Ak3	adenylate kinase 3	0.149
Abcb1a	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	0.144
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.143
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.137
Hccs	holocytochrome c synthetase	0.077
Syt1	synaptotagmin I	0.073
Scp2	sterol carrier protein 2, liver	0.057
Aco1	aconitase 1	0.056
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.052
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.050
Got1	glutamate oxaloacetate transaminase 1, soluble	0.050	Fly
Cyb5b	cytochrome b5 type B	0.048
Acaa2	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)	0.047
Sardh	sarcosine dehydrogenase	0.045
Ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.044
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.042
Lamp2	lysosomal-associated membrane protein 2	0.041
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.038
Glud1	glutamate dehydrogenase 1	0.036	Human
Gabra3	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3	0.035
Nadk	NAD kinase	0.033
Syp	synaptophysin	0.033
Vdac1	voltage-dependent anion channel 1	0.032
Cdh10	cadherin 10	0.032
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.032
Dbi	diazepam binding inhibitor	0.032
Gad2	glutamic acid decarboxylase 2	0.030
1110002B05Rik	RIKEN cDNA 1110002B05 gene	0.029
Akap1	A kinase (PRKA) anchor protein 1	0.029
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.028
Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	0.028
Decr1	2,4-dienoyl CoA reductase 1, mitochondrial	0.027
Sc4mol	sterol-C4-methyl oxidase-like	0.027
Cat	catalase	0.027
Slc12a5	solute carrier family 12, member 5	0.027
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.026
Ethe1	ethylmalonic encephalopathy 1	0.025
Mpi	mannose phosphate isomerase	0.025
Nefl	neurofilament, light polypeptide	0.025
Slc25a3	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3	0.024
Ckmt1	creatine kinase, mitochondrial 1, ubiquitous	0.024
Ugdh	UDP-glucose dehydrogenase	0.023
4931406C07Rik	RIKEN cDNA 4931406C07 gene	0.023
Bpnt1	bisphosphate 3'-nucleotidase 1	0.023
Gcdh	glutaryl-Coenzyme A dehydrogenase	0.023
Cyb5	cytochrome b-5	0.023
Gpr12	G-protein coupled receptor 12	0.022
Pkm2	pyruvate kinase, muscle	0.022
Pex5	peroxisomal biogenesis factor 5	0.022
Tmem19	transmembrane protein 19	0.022
Gabrb1	gamma-aminobutyric acid (GABA) A receptor, subunit beta 1	0.021
Pcx	pyruvate carboxylase	0.021
Sh3gl2	SH3-domain GRB2-like 2	0.021
Idh3a	isocitrate dehydrogenase 3 (NAD+) alpha	0.020
Mrpl10	mitochondrial ribosomal protein L10	0.020
Sc5d	sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)	0.020
Tagln3	transgelin 3	0.020
Gjb1	gap junction protein, beta 1	0.019
Rnf5	ring finger protein 5	0.019
Ptprd	protein tyrosine phosphatase, receptor type, D	0.019
1500003O03Rik	RIKEN cDNA 1500003O03 gene	0.019
Hsd17b4	hydroxysteroid (17-beta) dehydrogenase 4	0.019
Calb2	calbindin 2	0.019
Rac1	RAS-related C3 botulinum substrate 1	0.018
Kif1a	kinesin family member 1A	0.018
Acsl1	acyl-CoA synthetase long-chain family member 1	0.018
Olig1	oligodendrocyte transcription factor 1	0.018
Gldc	glycine decarboxylase	0.018
Nln	neurolysin (metallopeptidase M3 family)	0.018
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.018
Suclg2	succinate-Coenzyme A ligase, GDP-forming, beta subunit	0.018
Pipox	pipecolic acid oxidase	0.018
Dab1	disabled homolog 1 (Drosophila)	0.018
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.018
Decr2	2-4-dienoyl-Coenzyme A reductase 2, peroxisomal	0.017
Idi1	isopentenyl-diphosphate delta isomerase	0.017
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.017
Got2	glutamate oxaloacetate transaminase 2, mitochondrial	0.017	Fly
Slc25a5	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5	0.017
Acat2	acetyl-Coenzyme A acetyltransferase 2	0.016
Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	0.016
Etfdh	electron transferring flavoprotein, dehydrogenase	0.016
Faah	fatty acid amide hydrolase	0.016
Vstm2a	V-set and transmembrane domain containing 2A	0.016
Slc7a10	solute carrier family 7 (cationic amino acid transporter, y+ system), member 10	0.016
Lrrtm1	leucine rich repeat transmembrane neuronal 1	0.016
Syn2	synapsin II	0.016
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.016
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.015
Dgat2	diacylglycerol O-acyltransferase 2	0.015
Shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.015
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.015
Pccb	propionyl Coenzyme A carboxylase, beta polypeptide	0.015
Adam11	a disintegrin and metallopeptidase domain 11	0.015
Pitpna	phosphatidylinositol transfer protein, alpha	0.015
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	0.015
Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.014
Ciapin1	cytokine induced apoptosis inhibitor 1	0.014
Tecr	trans-2,3-enoyl-CoA reductase	0.014
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.014
Mfsd1	major facilitator superfamily domain containing 1	0.014
Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	0.014
Aqp4	aquaporin 4	0.014
Mgat3	mannoside acetylglucosaminyltransferase 3	0.013
Acy1	aminoacylase 1	0.013
Slc12a7	solute carrier family 12, member 7	0.013
Fam84a	family with sequence similarity 84, member A	0.013
Mccc2	methylcrotonoyl-Coenzyme A carboxylase 2 (beta)	0.013
Aldh3a2	aldehyde dehydrogenase family 3, subfamily A2	0.013
Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	0.013
Pmpca	peptidase (mitochondrial processing) alpha	0.013
Cldn2	claudin 2	0.013
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.013
Upp2	uridine phosphorylase 2	0.013
Gpr162	G protein-coupled receptor 162	0.013
Lypla1	lysophospholipase 1	0.013
Acly	ATP citrate lyase	0.013
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.013
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.013
Kif5a	kinesin family member 5A	0.013
Abcd3	ATP-binding cassette, sub-family D (ALD), member 3	0.012
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.012
Scn1a	sodium channel, voltage-gated, type I, alpha	0.012
Csnk2b	casein kinase 2, beta polypeptide	0.012
Aldoa	aldolase A, fructose-bisphosphate	0.012
Nptx1	neuronal pentraxin 1	0.012
Ngef	neuronal guanine nucleotide exchange factor	0.012
Aldob	aldolase B, fructose-bisphosphate	0.012
Gna12	guanine nucleotide binding protein, alpha 12	0.012
Homer1	homer homolog 1 (Drosophila)	0.012
Pex19	peroxisomal biogenesis factor 19	0.012
Lap3	leucine aminopeptidase 3	0.012
Gpr37l1	G protein-coupled receptor 37-like 1	0.012
Tubb4	tubulin, beta 4	0.012
Mobp	myelin-associated oligodendrocytic basic protein	0.012
Gpt2	glutamic pyruvate transaminase (alanine aminotransferase) 2	0.012
Aldh9a1	aldehyde dehydrogenase 9, subfamily A1	0.011
Nsf	N-ethylmaleimide sensitive fusion protein	0.011
Aldh1l1	aldehyde dehydrogenase 1 family, member L1	0.011
Acp6	acid phosphatase 6, lysophosphatidic	0.011
Hadha	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	0.011
Sigmar1	sigma non-opioid intracellular receptor 1	0.011
Rab1	RAB1, member RAS oncogene family	0.011
Sema4g	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G	0.011
Pdha1	pyruvate dehydrogenase E1 alpha 1	0.011
Igfbp2	insulin-like growth factor binding protein 2	0.011
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.011
Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	0.011
Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25	0.011
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.011
Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	0.011
Klc4	kinesin light chain 4	0.011
Caln1	calneuron 1	0.011
Elk1	ELK1, member of ETS oncogene family	0.011
Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.011
Slc6a15	solute carrier family 6 (neurotransmitter transporter), member 15	0.011
Mlc1	megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)	0.011
Pdhx	pyruvate dehydrogenase complex, component X	0.011
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.010
Atp5g1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)	0.010
Aldh7a1	aldehyde dehydrogenase family 7, member A1	0.010
Dhcr24	24-dehydrocholesterol reductase	0.010
Kars	lysyl-tRNA synthetase	0.010
Efna3	ephrin A3	0.010
Gad1	glutamic acid decarboxylase 1	0.010
Slc25a22	solute carrier family 25 (mitochondrial carrier, glutamate), member 22	0.010
Rab9	RAB9, member RAS oncogene family	0.010
Aplp2	amyloid beta (A4) precursor-like protein 2	0.010
Glyr1	glyoxylate reductase 1 homolog (Arabidopsis)	0.010
Ntsr2	neurotensin receptor 2	0.010
Oat	ornithine aminotransferase	0.010