IMP

Process View

Mus musculus

3 genes annotated in mouse

positive regulation of type iii hypersensitivity

Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of type iii hypersensitivity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of type iii hypersensitivity" (in gray)

Name	Description	Probability	Func Analog Organism
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	1.000
Ptprc	protein tyrosine phosphatase, receptor type, C	0.995
Lyz2	lysozyme 2	0.971
Tyrobp	TYRO protein tyrosine kinase binding protein	0.961
Il2rg	interleukin 2 receptor, gamma chain	0.941
Lat	linker for activation of T cells	0.681
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.667
Tcra	T-cell receptor alpha chain	0.595
Lck	lymphocyte protein tyrosine kinase	0.449
Clec4n	C-type lectin domain family 4, member n	0.388
Cd247	CD247 antigen	0.333	Mouse
Ccr1	chemokine (C-C motif) receptor 1	0.319
Cd19	CD19 antigen	0.306
Fcgr3	Fc receptor, IgG, low affinity III	0.222
Msr1	macrophage scavenger receptor 1	0.210
Hcst	hematopoietic cell signal transducer	0.204
Ikzf1	IKAROS family zinc finger 1	0.201
C1qb	complement component 1, q subcomponent, beta polypeptide	0.196
Il2	interleukin 2	0.176
Rag2	recombination activating gene 2	0.172
Ifng	interferon gamma	0.168
Tnf	tumor necrosis factor	0.158
Apoe	apolipoprotein E	0.150
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.139
Fas	Fas (TNF receptor superfamily member 6)	0.135
C1qc	complement component 1, q subcomponent, C chain	0.125
Mpeg1	macrophage expressed gene 1	0.113
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.113
Ccl6	chemokine (C-C motif) ligand 6	0.108
C3	complement component 3	0.102
Ccl9	chemokine (C-C motif) ligand 9	0.100
Aif1	allograft inflammatory factor 1	0.096
AF251705	cDNA sequence AF251705	0.093
Rag1	recombination activating gene 1	0.082
C3ar1	complement component 3a receptor 1	0.072
Ctss	cathepsin S	0.065
Csf1r	colony stimulating factor 1 receptor	0.061
Il7r	interleukin 7 receptor	0.060
Ly86	lymphocyte antigen 86	0.055
Lyz1	lysozyme 1	0.055
Il15	interleukin 15	0.054
Foxn1	forkhead box N1	0.043
Mrc1	mannose receptor, C type 1	0.042
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.040
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.038
Il10	interleukin 10	0.038
Cd52	CD52 antigen	0.038
Sfpi1	SFFV proviral integration 1	0.037
Cd14	CD14 antigen	0.036
Itk	IL2-inducible T-cell kinase	0.034
Fyb	FYN binding protein	0.032
Cd68	CD68 antigen	0.032
Fasl	Fas ligand (TNF superfamily, member 6)	0.032
Ccl12	chemokine (C-C motif) ligand 12	0.030
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.028
Zap70	zeta-chain (TCR) associated protein kinase	0.027
Hck	hemopoietic cell kinase	0.027
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.027
Il1b	interleukin 1 beta	0.023
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.023
Cd86	CD86 antigen	0.022
Ccr5	chemokine (C-C motif) receptor 5	0.022
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.021
Cybb	cytochrome b-245, beta polypeptide	0.021
Clec4d	C-type lectin domain family 4, member d	0.020
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.020	Mouse
Calcrl	calcitonin receptor-like	0.020
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.019
Selp	selectin, platelet	0.019
Fyn	Fyn proto-oncogene	0.018
Ifngr1	interferon gamma receptor 1	0.018
Adm	adrenomedullin	0.018
Inpp5d	inositol polyphosphate-5-phosphatase D	0.017
Fcgr1	Fc receptor, IgG, high affinity I	0.016
Plek	pleckstrin	0.016
Tbxas1	thromboxane A synthase 1, platelet	0.016
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.016
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.016
Folr2	folate receptor 2 (fetal)	0.014
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.014
Il2rb	interleukin 2 receptor, beta chain	0.013
Rhoh	ras homolog gene family, member H	0.013
Itgb2	integrin beta 2	0.013
Pf4	platelet factor 4	0.012
Fcgr4	Fc receptor, IgG, low affinity IV	0.012
B2m	beta-2 microglobulin	0.012
Tlr2	toll-like receptor 2	0.012
Clec7a	C-type lectin domain family 7, member a	0.012
Ccl3	chemokine (C-C motif) ligand 3	0.012
Clec4a2	C-type lectin domain family 4, member a2	0.012
Casp1	caspase 1	0.011
Gm11428	predicted gene 11428	0.011
Tlr7	toll-like receptor 7	0.011
Fpr1	formyl peptide receptor 1	0.011
Cd40	CD40 antigen	0.011
Ccl8	chemokine (C-C motif) ligand 8	0.011
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.010
Gpr132	G protein-coupled receptor 132	0.010
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.010
Myd88	myeloid differentiation primary response gene 88	0.010
Hmox1	heme oxygenase (decycling) 1	0.010
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.010
Fpr2	formyl peptide receptor 2	0.010
Cxcr2	chemokine (C-X-C motif) receptor 2	0.010