IMP
Process View
mitochondrial outer membrane permeabilization involved in programmed cell death
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "mitochondrial outer membrane permeabilization involved in programmed cell death"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Bax | BCL2-associated X protein | 1.000 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 1.000 | Mouse | |
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 1.000 | ||
| Bak1 | BCL2-antagonist/killer 1 | 0.992 | Mouse | |
| Bcl2l1 | BCL2-like 1 | 0.958 | Mouse | |
| Trp53 | transformation related protein 53 | 0.599 | ||
| Igh | immunoglobulin heavy chain complex | 0.460 | ||
| Axin1 | axin 1 | 0.449 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.446 | ||
| Kit | kit oncogene | 0.410 | ||
| Lyst | lysosomal trafficking regulator | 0.382 | ||
| Mta1 | metastasis associated 1 | 0.350 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.347 | ||
| Sharpin | SHANK-associated RH domain interacting protein | 0.296 | ||
| Pdcd6ip | programmed cell death 6 interacting protein | 0.246 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.237 | ||
| Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.170 | ||
| 2700094K13Rik | RIKEN cDNA 2700094K13 gene | 0.157 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.144 | ||
| Tcrb | T-cell receptor beta chain | 0.116 | ||
| Bbc3 | BCL2 binding component 3 | 0.106 | ||
| Pax2 | paired box gene 2 | 0.100 | ||
| Six2 | sine oculis-related homeobox 2 homolog (Drosophila) | 0.096 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.095 | ||
| Tcrd | T-cell receptor delta chain | 0.091 | ||
| Arpc4 | actin related protein 2/3 complex, subunit 4 | 0.085 | ||
| Atxn2 | ataxin 2 | 0.084 | ||
| Mtor | mechanistic target of rapamycin (serine/threonine kinase) | 0.083 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.081 | ||
| Mfn2 | mitofusin 2 | 0.064 | ||
| Mapk14 | mitogen-activated protein kinase 14 | 0.063 | ||
| Bmf | BCL2 modifying factor | 0.049 | ||
| Dnm1 | dynamin 1 | 0.047 | ||
| Traf3ip2 | TRAF3 interacting protein 2 | 0.046 | ||
| Mapk1 | mitogen-activated protein kinase 1 | 0.045 | ||
| Wt1 | Wilms tumor 1 homolog | 0.045 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.045 | ||
| Pik3r2 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) | 0.044 | ||
| Usp9x | ubiquitin specific peptidase 9, X chromosome | 0.043 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.040 | ||
| Eci2 | enoyl-Coenzyme A delta isomerase 2 | 0.034 | ||
| Bid | BH3 interacting domain death agonist | 0.033 | ||
| Gstz1 | glutathione transferase zeta 1 (maleylacetoacetate isomerase) | 0.032 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.032 | ||
| Nubp1 | nucleotide binding protein 1 | 0.032 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.029 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.028 | ||
| Hadha | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 0.027 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.027 | ||
| Bhlhe40 | basic helix-loop-helix family, member e40 | 0.024 | ||
| Usp42 | ubiquitin specific peptidase 42 | 0.024 | ||
| Gata3 | GATA binding protein 3 | 0.024 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.022 | ||
| Atp5a1 | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 | 0.021 | ||
| Ehd3 | EH-domain containing 3 | 0.021 | ||
| Rfc2 | replication factor C (activator 1) 2 | 0.021 | ||
| Gsk3a | glycogen synthase kinase 3 alpha | 0.021 | ||
| Mapk11 | mitogen-activated protein kinase 11 | 0.020 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.019 | ||
| Ep300 | E1A binding protein p300 | 0.019 | ||
| Cycs | cytochrome c, somatic | 0.019 | ||
| Rock2 | Rho-associated coiled-coil containing protein kinase 2 | 0.017 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.016 | ||
| Ern1 | endoplasmic reticulum (ER) to nucleus signalling 1 | 0.016 | ||
| Galk1 | galactokinase 1 | 0.016 | ||
| Dab1 | disabled homolog 1 (Drosophila) | 0.015 | ||
| Pten | phosphatase and tensin homolog | 0.015 | ||
| Acd | adrenocortical dysplasia | 0.015 | ||
| Nphp4 | nephronophthisis 4 (juvenile) homolog (human) | 0.015 | ||
| Pmm1 | phosphomannomutase 1 | 0.015 | ||
| Alad | aminolevulinate, delta-, dehydratase | 0.014 | ||
| Bnip3l | BCL2/adenovirus E1B interacting protein 3-like | 0.014 | ||
| Acadm | acyl-Coenzyme A dehydrogenase, medium chain | 0.014 | ||
| Atxn7l3 | ataxin 7-like 3 | 0.014 | ||
| Ssna1 | Sjogren's syndrome nuclear autoantigen 1 | 0.014 | ||
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.013 | ||
| Nefl | neurofilament, light polypeptide | 0.013 | ||
| Cmbl | carboxymethylenebutenolidase-like (Pseudomonas) | 0.013 | ||
| Nans | N-acetylneuraminic acid synthase (sialic acid synthase) | 0.013 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.013 | ||
| Aes | amino-terminal enhancer of split | 0.013 | ||
| 2310036O22Rik | RIKEN cDNA 2310036O22 gene | 0.013 | ||
| Dach1 | dachshund 1 (Drosophila) | 0.013 | ||
| Ube3a | ubiquitin protein ligase E3A | 0.013 | ||
| Ret | ret proto-oncogene | 0.013 | ||
| Idh3a | isocitrate dehydrogenase 3 (NAD+) alpha | 0.012 | ||
| Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.012 | ||
| Bach1 | BTB and CNC homology 1 | 0.012 | ||
| Sox2 | SRY-box containing gene 2 | 0.012 | ||
| Pgam1 | phosphoglycerate mutase 1 | 0.012 | ||
| Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.012 | ||
| Ikzf3 | IKAROS family zinc finger 3 | 0.012 | ||
| Rps6ka5 | ribosomal protein S6 kinase, polypeptide 5 | 0.012 | ||
| Nr2c2 | nuclear receptor subfamily 2, group C, member 2 | 0.012 | ||
| Akt1 | thymoma viral proto-oncogene 1 | 0.012 | ||
| Foxg1 | forkhead box G1 | 0.012 | ||
| Mapk9 | mitogen-activated protein kinase 9 | 0.011 | ||
| Zmym2 | zinc finger, MYM-type 2 | 0.011 | ||
| Lrrk2 | leucine-rich repeat kinase 2 | 0.011 | ||
| Tssc4 | tumor-suppressing subchromosomal transferable fragment 4 | 0.010 | ||
| Ppp1ca | protein phosphatase 1, catalytic subunit, alpha isoform | 0.010 | ||
| Fbxw7 | F-box and WD-40 domain protein 7 | 0.010 |