IMP

Process View

Mus musculus

3 genes annotated in mouse

trochlear nerve development

The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "trochlear nerve development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "trochlear nerve development" (in gray)

Name	Description	Probability	Func Analog Organism
Eya1	eyes absent 1 homolog (Drosophila)	0.988
Chrd	chordin	0.970
Otx2	orthodenticle homolog 2 (Drosophila)	0.970
Msx1	homeobox, msh-like 1	0.964
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.942
Shh	sonic hedgehog	0.922
Foxg1	forkhead box G1	0.897
Isl1	ISL1 transcription factor, LIM/homeodomain	0.873
Gbx2	gastrulation brain homeobox 2	0.816
Nog	noggin	0.780
Emx1	empty spiracles homolog 1 (Drosophila)	0.751
Sox9	SRY-box containing gene 9	0.742
Hand2	heart and neural crest derivatives expressed transcript 2	0.717
Gsc	goosecoid homeobox	0.665
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.538
Bmp7	bone morphogenetic protein 7	0.520
Tcfap2a	transcription factor AP-2, alpha	0.512
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.507
Gli3	GLI-Kruppel family member GLI3	0.500
Ret	ret proto-oncogene	0.461
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.455
Dlx5	distal-less homeobox 5	0.430
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.412
Prrx2	paired related homeobox 2	0.391	Mouse
Bmp2	bone morphogenetic protein 2	0.380
Phox2a	paired-like homeobox 2a	0.370
Sox2	SRY-box containing gene 2	0.370
Hes5	hairy and enhancer of split 5 (Drosophila)	0.365	Mouse
Fgf8	fibroblast growth factor 8	0.358
Hes3	hairy and enhancer of split 3 (Drosophila)	0.301
Ednra	endothelin receptor type A	0.264
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.262
Hand1	heart and neural crest derivatives expressed transcript 1	0.238
Nrg1	neuregulin 1	0.236
Pax3	paired box gene 3	0.234
Smo	smoothened homolog (Drosophila)	0.210
Tbx1	T-box 1	0.178
Fgfr1	fibroblast growth factor receptor 1	0.176
Hoxa2	homeobox A2	0.137
Prrx1	paired related homeobox 1	0.124	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.096
Hesx1	homeobox gene expressed in ES cells	0.095
Hes1	hairy and enhancer of split 1 (Drosophila)	0.088
Lhx3	LIM homeobox protein 3	0.078
Nrtn	neurturin	0.076
Bdnf	brain derived neurotrophic factor	0.075
Dlx6	distal-less homeobox 6	0.074
Lhx5	LIM homeobox protein 5	0.071
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.071
Rb1	retinoblastoma 1	0.070
Foxc2	forkhead box C2	0.064
Foxi3	forkhead box I3	0.058
Ntf3	neurotrophin 3	0.055
En1	engrailed 1	0.053
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.051
Hoxa1	homeobox A1	0.049
Msx2	homeobox, msh-like 2	0.046
Otx1	orthodenticle homolog 1 (Drosophila)	0.044
Gdnf	glial cell line derived neurotrophic factor	0.043
Fgf10	fibroblast growth factor 10	0.040
Alx4	aristaless-like homeobox 4	0.040
Gli2	GLI-Kruppel family member GLI2	0.040
Jag1	jagged 1	0.040
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.040
Pax6	paired box gene 6	0.039
Wnt1	wingless-related MMTV integration site 1	0.038
Foxc1	forkhead box C1	0.038
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.038
Sox10	SRY-box containing gene 10	0.035
Hoxb1	homeobox B1	0.035
Ptk7	PTK7 protein tyrosine kinase 7	0.031
Pbx1	pre B-cell leukemia transcription factor 1	0.028
Alx3	aristaless-like homeobox 3	0.028
Runx2	runt related transcription factor 2	0.027
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.025
Hoxd3	homeobox D3	0.025
Fgf15	fibroblast growth factor 15	0.024
Nkx3-2	NK3 homeobox 2	0.023
Neurog2	neurogenin 2	0.023
Rarb	retinoic acid receptor, beta	0.020
Fgf3	fibroblast growth factor 3	0.019
Lmx1b	LIM homeobox transcription factor 1 beta	0.018
Pax2	paired box gene 2	0.018
Bmp4	bone morphogenetic protein 4	0.018
Etv2	ets variant gene 2	0.018
Nos1	nitric oxide synthase 1, neuronal	0.018
Hmx3	H6 homeobox 3	0.017
Pax9	paired box gene 9	0.017
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.016
Vti1a	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)	0.016
Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.016
Acvr1	activin A receptor, type 1	0.016
Foxd2	forkhead box D2	0.015
Tlx3	T-cell leukemia, homeobox 3	0.015
Hoxd13	homeobox D13	0.015
Mn1	meningioma 1	0.015
Wnt3a	wingless-related MMTV integration site 3A	0.014
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.014
Ntf5	neurotrophin 5	0.014
Twist1	twist homolog 1 (Drosophila)	0.014
Zeb1	zinc finger E-box binding homeobox 1	0.013
Srpx	sushi-repeat-containing protein	0.013
Tlx2	T-cell leukemia, homeobox 2	0.013
Tbx15	T-box 15	0.013
Phox2b	paired-like homeobox 2b	0.013	Mouse
Uncx	UNC homeobox	0.012
Twist2	twist homolog 2 (Drosophila)	0.012
Rara	retinoic acid receptor, alpha	0.012
Thbs2	thrombospondin 2	0.012
Hoxa3	homeobox A3	0.011
Efna2	ephrin A2	0.011
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.011
Hmx2	H6 homeobox 2	0.011
Lrp6	low density lipoprotein receptor-related protein 6	0.011
Emx2	empty spiracles homolog 2 (Drosophila)	0.011
Acads	acyl-Coenzyme A dehydrogenase, short chain	0.011
Ctrb1	chymotrypsinogen B1	0.011
Dlx1	distal-less homeobox 1	0.010
Sox1	SRY-box containing gene 1	0.010