IMP
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superoxide anion generation
The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "superoxide anion generation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.730 | Rat | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.499 | ||
| Ren1 | renin 1 structural | 0.456 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.350 | ||
| Fbn1 | fibrillin 1 | 0.333 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.297 | Rat | |
| Vav2 | vav 2 oncogene | 0.145 | ||
| Il1rn | interleukin 1 receptor antagonist | 0.124 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.107 | ||
| Apoe | apolipoprotein E | 0.074 | ||
| Lepr | leptin receptor | 0.069 | ||
| Lox | lysyl oxidase | 0.059 | ||
| Capg | capping protein (actin filament), gelsolin-like | 0.053 | ||
| Vdr | vitamin D receptor | 0.048 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.046 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.046 | ||
| Agtrap | angiotensin II, type I receptor-associated protein | 0.042 | ||
| Csf1r | colony stimulating factor 1 receptor | 0.039 | ||
| Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.039 | ||
| Tlr2 | toll-like receptor 2 | 0.038 | ||
| Gdf15 | growth differentiation factor 15 | 0.036 | ||
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.035 | ||
| Slc12a1 | solute carrier family 12, member 1 | 0.033 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.032 | ||
| C5ar1 | complement component 5a receptor 1 | 0.030 | ||
| Lmna | lamin A | 0.029 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.029 | ||
| Vav3 | vav 3 oncogene | 0.028 | ||
| Cd14 | CD14 antigen | 0.028 | ||
| Cd28 | CD28 antigen | 0.027 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.026 | Human | |
| Msr1 | macrophage scavenger receptor 1 | 0.026 | ||
| Vegfa | vascular endothelial growth factor A | 0.026 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.026 | ||
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.024 | ||
| Umod | uromodulin | 0.023 | ||
| Nr3c2 | nuclear receptor subfamily 3, group C, member 2 | 0.023 | ||
| Nfkbie | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.022 | ||
| Ftl1 | ferritin light chain 1 | 0.022 | ||
| Gstm1 | glutathione S-transferase, mu 1 | 0.021 | ||
| Slc14a2 | solute carrier family 14 (urea transporter), member 2 | 0.020 | ||
| Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.018 | ||
| Jag1 | jagged 1 | 0.018 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.017 | ||
| Clec4d | C-type lectin domain family 4, member d | 0.017 | ||
| Cxcl1 | chemokine (C-X-C motif) ligand 1 | 0.017 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.017 | ||
| Gm3776 | predicted gene 3776 | 0.017 | ||
| Gm14548 | predicted gene 14548 | 0.017 | ||
| Vav1 | vav 1 oncogene | 0.016 | ||
| Fcgr1 | Fc receptor, IgG, high affinity I | 0.016 | ||
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.016 | ||
| Cd40 | CD40 antigen | 0.016 | ||
| Slfn4 | schlafen 4 | 0.015 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.015 | ||
| Selp | selectin, platelet | 0.015 | ||
| Ces1d | carboxylesterase 1D | 0.015 | ||
| Cd68 | CD68 antigen | 0.015 | ||
| Ncf4 | neutrophil cytosolic factor 4 | 0.015 | ||
| Cyp2f2 | cytochrome P450, family 2, subfamily f, polypeptide 2 | 0.014 | ||
| Braf | Braf transforming gene | 0.014 | ||
| Igh | immunoglobulin heavy chain complex | 0.014 | ||
| Sla | src-like adaptor | 0.014 | ||
| Gstt1 | glutathione S-transferase, theta 1 | 0.014 | ||
| Plaur | plasminogen activator, urokinase receptor | 0.014 | ||
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.013 | ||
| Saa3 | serum amyloid A 3 | 0.012 | ||
| Ch25h | cholesterol 25-hydroxylase | 0.012 | ||
| Ccl12 | chemokine (C-C motif) ligand 12 | 0.012 | ||
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.012 | ||
| Ifi30 | interferon gamma inducible protein 30 | 0.012 | ||
| Slc15a3 | solute carrier family 15, member 3 | 0.011 | ||
| Itgam | integrin alpha M | 0.011 | ||
| Sfpi1 | SFFV proviral integration 1 | 0.011 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.011 | ||
| Rxra | retinoid X receptor alpha | 0.011 | ||
| Runx1 | runt related transcription factor 1 | 0.011 | ||
| Blnk | B-cell linker | 0.010 | ||
| Ms4a7 | membrane-spanning 4-domains, subfamily A, member 7 | 0.010 | ||
| Cd86 | CD86 antigen | 0.010 | ||
| Hsd3b4 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 | 0.010 |