IMP

Process View

Rattus norvegicus

24 genes annotated in rat

response to gamma radiation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in rat Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to gamma radiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to gamma radiation" (in gray)

Name	Description	Probability	Func Analog Organism
Il1b	interleukin 1 beta	0.884
Ccl2	chemokine (C-C motif) ligand 2	0.814
Cd14	CD14 molecule	0.746
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.744
Igsf6	immunoglobulin superfamily, member 6	0.666
Il1a	interleukin 1 alpha	0.664
Ptprc	protein tyrosine phosphatase, receptor type, C	0.574
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.472
Cxcl10	chemokine (C-X-C motif) ligand 10	0.457
Ccl3	chemokine (C-C motif) ligand 3	0.344	Rat
Casp1	caspase 1	0.344	Rat
Fos	FBJ osteosarcoma oncogene	0.343
Socs3	suppressor of cytokine signaling 3	0.340
Ccl4	chemokine (C-C motif) ligand 4	0.320	Rat
Cxcl2	chemokine (C-X-C motif) ligand 2	0.317
Egr2	early growth response 2	0.305
LOC100362824	caveolin 2-like	0.286
Cd44	Cd44 molecule	0.274
Cav2	caveolin 2	0.251	Rat
Nras	neuroblastoma ras oncogene	0.239
Tpm4	tropomyosin 4	0.236
Jak2	Janus kinase 2	0.218
Il1r2	interleukin 1 receptor, type II	0.211
Junb	jun B proto-oncogene	0.207
Adam17	ADAM metallopeptidase domain 17	0.201
Calcrl	calcitonin receptor-like	0.194
Cav1	caveolin 1, caveolae protein	0.191
Dusp6	dual specificity phosphatase 6	0.191
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.165
Cish	cytokine inducible SH2-containing protein	0.142	Rat
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.139
Ier2	immediate early response 2	0.121
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.117
Ccl7	chemokine (C-C motif) ligand 7	0.111
Il6	interleukin 6	0.103
Ets1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.103
Atf3	activating transcription factor 3	0.101
Plaur	plasminogen activator, urokinase receptor	0.089
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.088
Ly6c	Ly6-C antigen	0.081
Cd83	CD83 molecule	0.079
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.077
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.069
Ctsc	cathepsin C	0.066
Ier3	immediate early response 3	0.063
Hck	hemopoietic cell kinase	0.063
Lbr	lamin B receptor	0.058
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.057
Btg2	BTG family, member 2	0.056
Rgs1	regulator of G-protein signaling 1	0.052
S1pr2	sphingosine-1-phosphate receptor 2	0.052
Pdcl	phosducin-like	0.052
Socs2	suppressor of cytokine signaling 2	0.051	Rat
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.050
Myo1b	myosin Ib	0.049
Reg3b	regenerating islet-derived 3 beta	0.048
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.046
Ccl11	chemokine (C-C motif) ligand 11	0.046	Rat
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.046
Cd53	Cd53 molecule	0.045
Cxcl11	chemokine (C-X-C motif) ligand 11	0.042
Selp	selectin P	0.040
Nat1	N-acetyltransferase 1	0.040
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.040
Sell	selectin L	0.038
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.037
Nkg7	natural killer cell group 7 sequence	0.036
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.036
Cox6a2	cytochrome c oxidase, subunit VIa, polypeptide 2	0.036
Il2rb	interleukin 2 receptor, beta	0.035
Mmp12	matrix metallopeptidase 12	0.035
Tlr4	toll-like receptor 4	0.032
Gch1	GTP cyclohydrolase 1	0.031
Wipf1	WAS/WASL interacting protein family, member 1	0.031
Psme3	proteasome (prosome, macropain) activator subunit 3	0.030
Gtpbp4	GTP binding protein 4	0.030
Ccr2	chemokine (C-C motif) receptor 2	0.029
Rab20	RAB20, member RAS oncogene family	0.029
Tgm1	transglutaminase 1, K polypeptide	0.028
Neurl3	neuralized homolog 3 (Drosophila)	0.028
Hes2	hairy and enhancer of split 2 (Drosophila)	0.027
Sp1	Sp1 transcription factor	0.027
Cfd	complement factor D (adipsin)	0.027
Tlr7	toll-like receptor 7	0.026
Clec4a3	C-type lectin domain family 4, member a3	0.025
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.025
Runx1	runt-related transcription factor 1	0.025
Casp7	caspase 7	0.025	Rat
Zfp36	zinc finger protein 36	0.024
Plek	pleckstrin	0.024
Itgam	integrin, alpha M	0.024
Rrad	Ras-related associated with diabetes	0.024
Rara	retinoic acid receptor, alpha	0.024
Slfn3	schlafen 3	0.024
Cxcl3	chemokine (C-X-C motif) ligand 3	0.023	Rat
Ccr5	chemokine (C-C motif) receptor 5	0.023
Ripk3	receptor-interacting serine-threonine kinase 3	0.023
Il1r1	interleukin 1 receptor, type I	0.022
Pim1	pim-1 oncogene	0.022
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.022
Folr2	folate receptor 2 (fetal)	0.022
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.022
Tp53	tumor protein p53	0.022	Human
Tpm1	tropomyosin 1, alpha	0.021
RT1-Db1	RT1 class II, locus Db1	0.021
Sele	selectin E	0.021
Casp8	caspase 8	0.021	Rat
S100a8	S100 calcium binding protein A8	0.021
Gimap4	GTPase, IMAP family member 4	0.021
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.021
Aif1	allograft inflammatory factor 1	0.021
Tcf21	transcription factor 21	0.020
Cybb	cytochrome b-245, beta polypeptide	0.020	Rat
Fabp6	fatty acid binding protein 6, ileal	0.019
Ocm	oncomodulin	0.019
Rab32	RAB32, member RAS oncogene family	0.019
Epha3	Eph receptor A3	0.019
Ms4a11	membrane-spanning 4-domains, subfamily A, member 11	0.019
Cdk2	cyclin dependent kinase 2	0.019
Stat5b	signal transducer and activator of transcription 5B	0.018
Crem	cAMP responsive element modulator	0.018
Cyr61	cysteine-rich, angiogenic inducer, 61	0.018
Glipr1	GLI pathogenesis-related 1	0.018
Bnip2	BCL2/adenovirus E1B interacting protein 2	0.018
Mpeg1	macrophage expressed 1	0.018
Il1rap	interleukin 1 receptor accessory protein	0.018
Lig3	ligase III, DNA, ATP-dependent	0.018
Toe1	target of EGR1, member 1 (nuclear)	0.018
Ptgs2	prostaglandin-endoperoxide synthase 2	0.018
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.017
Prokr1	prokineticin receptor 1	0.017
Parp14	poly (ADP-ribose) polymerase family, member 14	0.017
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.017
Lcn2	lipocalin 2	0.017
Prss22	protease, serine, 22	0.017
Nhp2l1	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	0.016
Lpar6	lysophosphatidic acid receptor 6	0.016
Cd200r1	CD200 receptor 1	0.016
Clec2d	C-type lectin domain family 2, member d	0.016
B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.016
Ccl20	chemokine (C-C motif) ligand 20	0.016	Rat
Ccr1	chemokine (C-C motif) receptor 1	0.016
Plau	plasminogen activator, urokinase	0.016
Cxcl9	chemokine (C-X-C motif) ligand 9	0.015	Rat
Msn	moesin	0.015
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.015
Emcn	endomucin	0.015
Ryk	receptor-like tyrosine kinase	0.015
Arl11	ADP-ribosylation factor-like 11	0.015
Nolc1	nucleolar and coiled-body phosphoprotein 1	0.015
Caprin1	cell cycle associated protein 1	0.015
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.015
Hspb1	heat shock protein 1	0.015
Slfn2	schlafen 2	0.015
Cd86	CD86 molecule	0.014
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.014
Pion	pigeon homolog (Drosophila)	0.014
LOC363060	similar to RIKEN cDNA 1600029D21	0.014
Hk2	hexokinase 2	0.014
Cd38	CD38 molecule	0.014
Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	0.014
Adar	adenosine deaminase, RNA-specific	0.014
Prps2	phosphoribosyl pyrophosphate synthetase 2	0.014
Hist1h4b	histone cluster 1, H4b	0.014
Hspa1a	heat shock 70kD protein 1A	0.014
LOC100364500	RT1 class I, locus CE11-like	0.014
Bcl2	B-cell CLL/lymphoma 2	0.014	Mouse
Rwdd1	RWD domain containing 1	0.014
Gypc	glycophorin C (Gerbich blood group)	0.013
Thbd	thrombomodulin	0.013
Ccl17	chemokine (C-C motif) ligand 17	0.013
Klf4	Kruppel-like factor 4 (gut)	0.013
Prok2	prokineticin 2	0.013
Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	0.013
Golph3	golgi phosphoprotein 3 (coat-protein)	0.013
Casp6	caspase 6	0.013
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.013
Ccnd1	cyclin D1	0.013
Cks2	CDC28 protein kinase regulatory subunit 2	0.013
Cd8a	CD8a molecule	0.013
Hrh1	histamine receptor H 1	0.012
Kdr	kinase insert domain receptor	0.012
Casp2	caspase 2	0.012	Rat
Ggta1	glycoprotein, alpha-galactosyltransferase 1	0.012
Stx11	syntaxin 11	0.012
Hspb2	heat shock protein beta 2	0.012
Cd68	Cd68 molecule	0.011
Ncr1	natural cytotoxicity triggering receptor 1	0.011
Gbp2	guanylate binding protein 2	0.011
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.011
Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.011
Map4k5	mitogen-activated protein kinase kinase kinase kinase 5	0.011
Tfec	transcription factor EC	0.011
RGD1308722	similar to RIKEN cDNA A130042E20; open reading frame 57	0.011
Odf1	outer dense fiber of sperm tails 1	0.011
Abcb1b	ATP-binding cassette, subfamily B (MDR/TAP), member 1B	0.011
Gpx2	glutathione peroxidase 2	0.011
Fitm1	fat storage-inducing transmembrane protein 1	0.011
Ccl5	chemokine (C-C motif) ligand 5	0.011	Rat
PVR	poliovirus receptor	0.011
Pla2g5	phospholipase A2, group V	0.011
Defb4	defensin beta 4	0.011
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.011
Efna5	ephrin A5	0.011
Rps6kb1	ribosomal protein S6 kinase, polypeptide 1	0.011
Pxdn	peroxidasin homolog (Drosophila)	0.011
RT1-Ba	RT1 class II, locus Ba	0.011
Tcfe2a	transcription factor E2a	0.011
Ppif	peptidylprolyl isomerase F	0.011
Spp1	secreted phosphoprotein 1	0.011
Gata6	GATA binding protein 6	0.010
Hist1h2bh	histone cluster 1, H2bh	0.010
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.010
Ltb4r	leukotriene B4 receptor	0.010
Cmklr1	chemokine-like receptor 1	0.010
Nradd	neurotrophin receptor associated death domain	0.010