IMP

Process View

Rattus norvegicus

14 genes annotated in rat

c21 steroid hormone metabolic process

The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "c21 steroid hormone metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "c21 steroid hormone metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.261
Cyb5a	cytochrome b5 type A (microsomal)	0.204
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.187
LOC293989	cytochrome P450-like	0.186
LOC100361547	Cytochrome P450, family 2, subfamily c, polypeptide 7-like	0.175
Clca4	chloride channel accessory 4	0.175
Cyp2c22	cytochrome P450, family 2, subfamily c, polypeptide 22	0.136
Gabarapl2	GABA(A) receptor-associated protein like 2	0.123
Galnt5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	0.106
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.104
Rup2	urinary protein 2	0.088
Cgm4	carcinoembryonic antigen gene family 4	0.064
Hipk3	homeodomain interacting protein kinase 3	0.062
Slc16a8	solute carrier family 16, member 8 (monocarboxylic acid transporter 3)	0.058
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.057
Sult2a1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.056
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.054
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.054
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.049
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.047
Prss3	protease, serine, 3	0.043
Akr1c12	aldo-keto reductase family 1, member C12	0.042
Apoh	apolipoprotein H (beta-2-glycoprotein I)	0.042
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.040
Sult1c3	sulfotransferase family, cytosolic, 1C, member 3	0.040
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.040
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.040
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.036
Fabp1	fatty acid binding protein 1, liver	0.036
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.034
LOC494499	LOC494499 protein	0.033
Cyp2a2	cytochrome P450, family 2, subfamily a, polypeptide 2	0.032
Cyp2d2	cytochrome P450, family 2, subfamily d, polypeptide 2	0.031
Rdh7	retinol dehydrogenase 7	0.029
Ppp3r2	protein phosphatase 3, regulatory subunit B, beta isoform	0.029
Kcnh4	potassium voltage-gated channel, subfamily H (eag-related), member 4	0.028
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.027
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.027
Ptger3	prostaglandin E receptor 3 (subtype EP3)	0.026
Dpp4	dipeptidylpeptidase 4	0.026
Fam126b	family with sequence similarity 126, member B	0.025
Kcne1	potassium voltage-gated channel, Isk-related family, member 1	0.025
Klkb1	kallikrein B, plasma 1	0.023
Map3k9	mitogen-activated protein kinase kinase kinase 9	0.023
Gpr150	G protein-coupled receptor 150	0.022
Tipin	timeless interacting protein	0.022
Cyp3a18	cytochrome P450, family 3, subfamily a, polypeptide 18	0.021
Hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.021
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.021
Cyp17a1	cytochrome P450, family 17, subfamily a, polypeptide 1	0.020	Human Rat
Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	0.020
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.020
Ltb4r	leukotriene B4 receptor	0.020
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.020
Dlc1	deleted in liver cancer 1	0.019
A1i3	alpha-1-inhibitor III	0.019
Cox6a2	cytochrome c oxidase, subunit VIa, polypeptide 2	0.019
Star	steroidogenic acute regulatory protein	0.019
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.019
Si	sucrase-isomaltase (alpha-glucosidase)	0.019
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.018
Prlr	prolactin receptor	0.018
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.018
Cyp2c7	cytochrome P450, family 2, subfamily c, polypeptide 7	0.018
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.018
Foxi2	forkhead box I2	0.018
Myl7	myosin, light chain 7, regulatory	0.018
Aqp9	aquaporin 9	0.018
Ces1c	carboxylesterase 1C	0.018
Hrh2	histamine receptor H 2	0.017
Pim1	pim-1 oncogene	0.017
Akr1c14	aldo-keto reductase family 1, member C14	0.017	Human
Slco4a1	solute carrier organic anion transporter family, member 4a1	0.017
Mcee	methylmalonyl CoA epimerase	0.017
Sult2al1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1	0.017
Dio2	deiodinase, iodothyronine, type II	0.016
Crisp2	cysteine-rich secretory protein 2	0.016
Nudt8	nudix (nucleoside diphosphate linked moiety X)-type motif 8	0.016
Aldh6a1	aldehyde dehydrogenase 6 family, member A1	0.016
Smad3	SMAD family member 3	0.016
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.016
Fgb	fibrinogen beta chain	0.016
Ces2c	carboxylesterase 2C	0.016
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.015
Gjb3	gap junction protein, beta 3	0.015
Ces1f	carboxylesterase 1F	0.015
Ugt2b37	UDP-glucuronosyltransferase 2 family, member 37	0.015
Spink1	serine peptidase inhibitor, Kazal type 1	0.015
Rgn	regucalcin (senescence marker protein-30)	0.015
Ppard	peroxisome proliferator-activated receptor delta	0.015
Apob	apolipoprotein B	0.015
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.015
Spt1	salivary protein 1	0.014
Shc3	SHC (Src homology 2 domain containing) transforming protein 3	0.014
Aqp8	aquaporin 8	0.014
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.014	Rat
Sez6l2	seizure related 6 homolog (mouse)-like 2	0.014
Dmrta1	DMRT-like family A1	0.014
Dnase1l3	deoxyribonuclease 1-like 3	0.014
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.014
Rims1	regulating synaptic membrane exocytosis 1	0.014
Cmbl	carboxymethylenebutenolidase homolog (Pseudomonas)	0.014
P22k15	cystatin related protein 2	0.014
Fut1	fucosyltransferase 1	0.014
Dpyd	dihydropyrimidine dehydrogenase	0.014
Cyp3a23/3a1	cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1	0.013
Gabre	gamma-aminobutyric acid (GABA) A receptor, epsilon	0.013
Mettl7b	methyltransferase like 7B	0.013
Mgst2	microsomal glutathione S-transferase 2	0.013
Mamdc4	MAM domain containing 4	0.013
Pank2	pantothenate kinase 2 (Hallervorden-Spatz syndrome)	0.013
Hcrtr2	hypocretin (orexin) receptor 2	0.013
Sv2c	synaptic vesicle glycoprotein 2c	0.013
Drd1a	dopamine receptor D1A	0.013
Acadm	acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	0.012
Lox	lysyl oxidase	0.012
Keg1	kidney expressed gene 1	0.012
Pemt	phosphatidylethanolamine N-methyltransferase	0.012
Cyp2b2	cytochrome P450, family 2, subfamily b, polypeptide 2	0.012
Eps8l3	EPS8-like 3	0.012
As3mt	arsenic (+3 oxidation state) methyltransferase	0.012
Ugt1a3	UDP glycosyltransferase 1 family, polypeptide A3	0.012
Hbg1	hemoglobin, gamma A	0.012
Cyp2b1	cytochrome P450, family 2, subfamily b, polypeptide 1	0.011
G6pc	glucose-6-phosphatase, catalytic subunit	0.011
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.011
Cyp2j4	cytochrome P450, family 2, subfamily j, polypeptide 4	0.011
Otc	ornithine carbamoyltransferase	0.011
LOC685527	hypothetical protein LOC685527	0.011
Pla2g1b	phospholipase A2, group IB, pancreas	0.011
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.011
Upk3bl	uroplakin 3B-like	0.011
Lpar2	lysophosphatidic acid receptor 2	0.011
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.011
Shbg	sex hormone binding globulin	0.011
Cyp3a9	cytochrome P450, family 3, subfamily a, polypeptide 9	0.010
Slc18a1	solute carrier family 18 (vesicular monoamine), member 1	0.010
Nepn	nephrocan	0.010
Atxn1	ataxin 1	0.010
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.010