IMP

Process View

Danio rerio

14 genes annotated in zebrafish

response to cadmium ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to cadmium ion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to cadmium ion" (in gray)

Name	Description	Probability	Func Analog Organism
gadd45ba	growth arrest and DNA-damage-inducible, beta a	0.975
gadd45aa	growth arrest and DNA-damage-inducible, alpha, a	0.723	Zebrafish
mcl1a	myeloid cell leukemia sequence 1a	0.610	Zebrafish
bcl2l1	bcl2-like 1	0.504	Zebrafish
hsp90a.2	heat shock protein 90-alpha 2	0.372
junb	jun B proto-oncogene	0.317
bida	BH3 interacting domain death agonist	0.198
zgc:92851	zgc:92851	0.197
zgc:55813	zgc:55813	0.187
ntn2	netrin 2	0.170
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.164
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.156
atp1b1a	ATPase, Na+/K+ transporting, beta 1a polypeptide	0.153
polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.149
pcna	proliferating cell nuclear antigen	0.147
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.147
socs3a	suppressor of cytokine signaling 3a	0.144
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.138
mcm4	MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae)	0.133
gadd45bb	growth arrest and DNA-damage-inducible, beta b	0.127	Zebrafish
bbc3	BCL2 binding component 3	0.126
igfbp1a	insulin-like growth factor binding protein 1a	0.124
copeb	core promoter element binding protein	0.122
atf3	activating transcription factor 3	0.112
atp1a1a.5	ATPase, Na+/K+ transporting, alpha 1a.5 polypeptide	0.107
mcl1b	myeloid cell leukemia sequence 1b	0.104	Zebrafish
btg2	B-cell translocation gene 2	0.104
socs1	suppressor of cytokine signaling 1	0.101
baxa	bcl2-associated X protein, a	0.100
zgc:162126	zgc:162126	0.093
mybl2	myeloblastosis oncogene-like 2	0.091
gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.087
mapk6	mitogen-activated protein kinase 6	0.087
nrg1	neuregulin 1	0.078
mapk3	mitogen-activated protein kinase 3	0.072	Fly
etv5a	ets variant 5a	0.069
psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.066
bcl2	B-cell leukemia/lymphoma 2	0.062	Zebrafish
fbln4	fibulin 4	0.059
cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.055
mapk7	mitogen-activated protein kinase 7	0.054
dusp4	dual specificity phosphatase 4	0.052
whsc1	Wolf-Hirschhorn syndrome candidate 1	0.052
dnajb1b	DnaJ (Hsp40) homolog, subfamily B, member 1b	0.052
LOC100000332	e3 ubiquitin-protein ligase RNF182-like	0.051
hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.051
mt2	metallothionein 2	0.050
prox2	prospero homeobox 2	0.049
ercc2	excision repair cross-complementing rodent repair deficiency, complementation group 2	0.048
cygb2	cytoglobin 2	0.044
birc5a	baculoviral IAP repeat-containing 5a	0.042
sgk1	serum/glucocorticoid regulated kinase 1	0.041
dusp1	dual specificity phosphatase 1	0.041
ptgds	prostaglandin D2 synthase	0.041
pdlim1	PDZ and LIM domain 1 (elfin)	0.040
mvp	major vault protein	0.038
cyp11a1	cytochrome P450, subfamily XIA, polypeptide 1	0.036	Rat
fkbp5	FK506 binding protein 5	0.035
cyp1a	cytochrome P450, family 1, subfamily A	0.035	Mouse
LOC565839	tumor necrosis factor alpha-induced protein 2-like	0.035
zgc:64115	zgc:64115	0.035
vtg1	vitellogenin 1	0.034
map2k4b	mitogen-activated protein kinase kinase 4b	0.034
comta	catechol-O-methyltransferase a	0.033
rbp4	retinol binding protein 4, plasma	0.030
cx32.3	connexin 32.3	0.030
hsp70	heat shock cognate 70-kd protein	0.030
hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.030
xbp1	X-box binding protein 1	0.030
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.030
tgfbr2	transforming growth factor, beta receptor II	0.029
zgc:110340	zgc:110340	0.029
ccng1	cyclin G1	0.029
dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.028
cd63	Cd63 antigen	0.027
vcana	versican a	0.027
trim25	tripartite motif-containing 25	0.027
cldn15la	claudin 15-like a	0.027
jun	jun proto-oncogene	0.026
sat1a	spermidine/spermine N1-acetyltransferase 1a	0.026
bik	BCL2-interacting killer (apoptosis-inducing)	0.026
hspa4a	heat shock protein 4a	0.025
junbl	jun B proto-oncogene, like	0.025
cyp1c2	cytochrome P450, family 1, subfamily C, polypeptide 2	0.025
lgals2b	lectin, galactoside-binding, soluble, 2b	0.025
baxb	bcl2-associated X protein, b	0.024	Zebrafish
LOC562316	klotho-like	0.024
wnt5a	wingless-type MMTV integration site family, member 5a	0.024
vdac2	voltage-dependent anion channel 2	0.024
hbegfa	heparin-binding EGF-like growth factor a	0.023
zbtb4	zinc finger and BTB domain containing 4	0.023
col7a1l	collagen type VII alpha 1-like	0.023
hibadhb	3-hydroxyisobutyrate dehydrogenase b	0.023
trim71	tripartite motif-containing 71	0.022
insl5a	insulin-like 5a	0.022
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.022
epo	erythropoietin	0.021
nap1l1	nucleosome assembly protein 1, like 1	0.021
rrm1	ribonucleotide reductase M1 polypeptide	0.021
tpsn	tapasin	0.021
eif4ebp3l	eukaryotic translation initiation factor 4E binding protein 3, like	0.021
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.021
itga7	integrin, alpha 7	0.020
nrg2b	neuregulin 2b	0.020
adcyap1r1a	adenylate cyclase activating polypeptide 1 receptor 1a	0.020
si:ch211-89f7.4	si:ch211-89f7.4	0.020
nr5a2	nuclear receptor subfamily 5, group A, member 2	0.020
neu4	sialidase 4	0.020
blmh	bleomycin hydrolase	0.020
mipa	major intrinsic protein of lens fiber a	0.020
prom1a	prominin 1a	0.020
bmf1	Bcl2 modifying factor 1	0.019
mxtx2	mix-type homeobox gene 2	0.019
eif4e1c	eukaryotic translation initiation factor 4E family member 1c	0.019
rps21	ribosomal protein S21	0.018
tecrb	trans-2,3-enoyl-CoA reductase b	0.018
sb:cb166	sb:cb166	0.018
atp1a1a.4	ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide	0.018
si:dkey-97i18.2	si:dkey-97i18.2	0.018
ahr1a	aryl hydrocarbon receptor 1a	0.018
vipr1	vasoactive intestinal peptide receptor 1	0.018
keap1a	kelch-like ECH-associated protein 1a	0.018
si:dkeyp-59a8.4	si:dkeyp-59a8.4	0.018
kbtbd8	kelch repeat and BTB (POZ) domain containing 8	0.017
sod1	superoxide dismutase 1, soluble	0.017
sdc2	syndecan 2	0.017
si:dkey-236e20.2	si:dkey-236e20.2	0.017
gadd45ab	growth arrest and DNA-damage-inducible, alpha, b	0.017	Zebrafish
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.017
ptgesl	prostaglandin E synthase 2-like	0.017
cryba2b	crystallin, beta A2b	0.017
ca2	carbonic anhydrase II	0.017
ahrra	aryl-hydrocarbon receptor repressor a	0.017
sult1st3	sulfotransferase family 1, cytosolic sulfotransferase 3	0.017
hsf4	heat shock transcription factor 4	0.016
malt1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.016
wnt10a	wingless-type MMTV integration site family, member 10a	0.016
LOC100005295	acetylcholine receptor subunit beta-like	0.016
numbl	numb homolog (Drosophila)-like	0.016
dnmt5	DNA (cytosine-5-)-methyltransferase 5	0.016
mapk12	mitogen-activated protein kinase 12	0.015	Fly
cyp2aa2	y cytochrome P450, family 2, subfamily AA, polypeptide 2	0.015
vps33b	vacuolar protein sorting 33B	0.015
crygm2d1	crystallin, gamma M2d1	0.015
cldn2	claudin 2	0.015
eno2	enolase 2	0.015
LOC568833	claudin-3-like	0.015
usp5	ubiquitin specific protease 5	0.014
si:ch211-124k10.1	si:ch211-124k10.1	0.014
im:7156396	im:7156396	0.014
adipor2	adiponectin receptor 2	0.014
smox	spermine oxidase	0.014
qk	quaking	0.014
sephs1	selenophosphate synthetase 1	0.014
ahrrb	aryl-hydrocarbon receptor repressor b	0.014
tnfb	tumor necrosis factor b (TNF superfamily, member 2)	0.014
nr5a5	nuclear receptor subfamily 5, group A, member 5	0.014
glula	glutamate-ammonia ligase (glutamine synthase) a	0.014
hspb1	heat shock protein, alpha-crystallin-related, 1	0.014
mapk1	mitogen-activated protein kinase 1	0.014	Fly
bad	BCL2-antagonist of cell death	0.013
ucp2	uncoupling protein 2	0.013
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.013
fcho2	FCH domain only 2	0.013
rps6ka3a	ribosomal protein S6 kinase, polypeptide 3a	0.013
tlr3	toll-like receptor 3	0.013
zgc:110053	zgc:110053	0.013
insl3	insulin-like 3 (Leydig cell)	0.013
slc5a8l	solute carrier family 5 (iodide transporter), member 8-like	0.013
sult3st1	sulfotransferase family 3, cytosolic sulfotransferase 1	0.013
bactin2	bactin2	0.013
mibp2	muscle-specific beta 1 integrin binding protein 2	0.013
cryba2a	crystallin, beta A2a	0.013
arl5c	ADP-ribosylation factor-like 5C	0.013
zgc:112056	zgc:112056	0.013
ppm1aa	protein phosphatase, Mg2+/Mn2+ dependent, 1Aa	0.013
LOC567131	calcitonin gene-related peptide type 1 receptor-like	0.013
psmb9a	proteasome (prosome, macropain) subunit, beta type, 9a	0.013
fxyd1	FXYD domain containing ion transport regulator 1 (phospholemman)	0.013
igfbp1b	insulin-like growth factor binding protein 1b	0.012
mospd2	motile sperm domain containing 2	0.012
wars	tryptophanyl-tRNA synthetase	0.012
chac1	ChaC, cation transport regulator-like 1	0.012
cacnb2a	calcium channel, voltage-dependent, beta 2a	0.012
cdh17	cadherin 17, LI cadherin (liver-intestine)	0.012
rpa1	replication protein A1	0.012
vtg4	vitellogenin 4	0.012
cyp2p6	cytochrome P450, family 2, subfamily P, polypeptide 6	0.012
mapk8b	mitogen-activated protein kinase 8b	0.012	Mouse Fly
abat	4-aminobutyrate aminotransferase	0.012
LOC568935	ARF GTPase-activating protein GIT1-like	0.012
slc16a9b	solute carrier family 16 (monocarboxylic acid transporters), member 9b	0.012
h2afy2	H2A histone family, member Y2	0.012
crabp1b	cellular retinoic acid binding protein 1b	0.012
mmp9	matrix metalloproteinase 9	0.012
unc5db	unc-5 homolog Db (C. elegans)	0.012
egr2a	early growth response 2a	0.012
wu:fj59f04	wu:fj59f04	0.012
COX1	cytochrome c oxidase subunit I	0.011
LOC792676	similar to N-myc-interactor (Nmi) (N-myc and STAT interactor)	0.011
slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	0.011
stat1a	signal transduction and activation of transcription 1a	0.011
cxc46	CXC chemokine 46	0.011
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.011
phlda2	pleckstrin homology-like domain, family A, member 2	0.011
zgc:63599	zgc:63599	0.011
si:dkeyp-7c9.1	si:dkeyp-7c9.1	0.011
cyp2aa1	cytochrome P450, family 2, subfamily AA, polypeptide 1	0.011
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.011
msh2	mutS homolog 2 (E. coli)	0.011
epas1b	endothelial PAS domain protein 1b	0.011
dnajb6b	DnaJ (Hsp40) homolog, subfamily B, member 6b	0.011
pho	phoenix	0.011
phax	phosphorylated adaptor for RNA export	0.011
cyp2v2	cytochrome P450, family 2, subfamily V, polypeptide 2	0.011
gstp1	glutathione S-transferase pi	0.011
LOC100002494	relaxin/insulin-like family peptide receptor 3-like	0.011
efnb2a	ephrin B2a	0.011
csrp3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.011
itpk1	inositol 1,3,4-triphosphate 5/6 kinase	0.011
ndrg1	N-myc downstream regulated gene 1	0.011
pttg1ipb	pituitary tumor-transforming 1 interacting protein b	0.011
LOC566020	Gig2-like protein DreO	0.011
adrb3a	adrenergic receptor, beta 3a	0.011
cdh11	cadherin 11, osteoblast	0.011
irf7	interferon regulatory factor 7	0.011
irf9	interferon regulatory factor 9	0.011
sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.011
psmb5	proteasome (prosome, macropain) subunit, beta type, 5	0.010
abcb3	ATP-binding cassette, sub-family B (MDR/TAP), member 3	0.010
fbxl14b	F-box and leucine-rich repeat protein 14b	0.010
tmf1	TATA element modulatory factor 1	0.010
csnk1db	casein kinase 1, delta b	0.010
park7	parkinson disease (autosomal recessive, early onset) 7	0.010
cyp3c1	cytochrome P450, family 3, subfamily c, polypeptide 1	0.010	Rat
ctage5	CTAGE family, member 5	0.010
sdcbp	syndecan binding protein (syntenin)	0.010
pim1	pim-1 oncogene	0.010
zgc:64161	zgc:64161	0.010
cldn12	claudin 12	0.010
pcdh1a4	protocadherin 1 alpha 4	0.010
hbs1l	HBS1-like (S. cerevisiae)	0.010