IMP

Process View

Danio rerio

13 genes annotated in zebrafish

cell differentiation involved in kidney development

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell differentiation involved in kidney development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell differentiation involved in kidney development" (in gray)

Name	Description	Probability	Func Analog Organism
osr2	odd-skipped related 2 (Drosophila)	0.826	Zebrafish
tbx1	T-box 1	0.590
notch1a	notch homolog 1a	0.425	Mouse
wt1b	wilms tumor 1b	0.310	Zebrafish Mouse
hnf1ba	HNF1 homeobox Ba	0.293
lhx1a	LIM homeobox 1a	0.249	Mouse
wt1a	wilms tumor 1a	0.212
lamc1	laminin, gamma 1	0.201
hnf1bb	HNF1 homeobox Bb	0.197
bmp2b	bone morphogenetic protein 2b	0.153
myod1	myogenic differentiation 1	0.145
mecom	MDS1 and EVI1 complex locus	0.140
jag1b	jagged 1b	0.123
nphs2	nephrosis 2, idiopathic, steroid-resistant (podocin)	0.115
eng2a	engrailed 2a	0.104
pax2a	paired box gene 2a	0.093	Mouse
sim1a	single-minded homolog 1a (Drosophila)	0.090
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.086
osr1	odd-skipped related 1 (Drosophila)	0.082
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.071
tbx5a	T-box 5a	0.068
adipoql	adiponectin, C1Q and collagen domain containing, like	0.066	Mouse
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.064	Human Zebrafish
wtip	Wilms tumor 1 interacting protein	0.060
pax8	paired box gene 8	0.057	Mouse
emx1	empty spiracles homeobox 1	0.054
smyd1b	SET and MYND domain containing 1b	0.051
foxo3b	forkhead box O3b	0.050
nkx2.2a	NK2 transcription factor related 2a	0.049
epha4b	eph receptor A4b	0.047
foxa2	forkhead box A2	0.046
ren	renin	0.045
hoxb2a	homeo box B2a	0.044
vegfab	vascular endothelial growth factor Ab	0.041
hoxd3a	homeo box D3a	0.040
wnt1	wingless-type MMTV integration site family, member 1	0.039
foxn4	forkhead box N4	0.039
plce1	phospholipase C, epsilon 1	0.039
epha4a	eph receptor A4a	0.037
tbx5b	T-box 5b	0.037
fli1a	friend leukemia integration 1a	0.036
tagln	transgelin	0.036
kirrel3l	kin of IRRE like 3 like	0.034
etv2	ets variant gene 2	0.034
egr1	early growth response 1	0.033	Zebrafish
klf2a	Kruppel-like factor 2a	0.032
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.032
yap1	Yes-associated protein 1	0.032	Mouse
smchd1	structural maintenance of chromosomes flexible hinge domain containing 1	0.032
egr2a	early growth response 2a	0.030	Zebrafish
bmp4	bone morphogenetic protein 4	0.030	Mouse
colec11	collectin sub-family member 11	0.030
podxl	podocalyxin-like	0.030
adipor2	adiponectin receptor 2	0.029
epb4.1l4	erythrocyte protein band 4.1-like 4	0.029
nkx2.1a	NK2 homeobox 1a	0.028
hand2	heart and neural crest derivatives expressed transcript 2	0.028
gli1	GLI-Kruppel family member 1	0.027
elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.026
fzd7b	frizzled homolog 7b	0.026
prdm1a	PR domain containing 1a, with ZNF domain	0.025
cobl	cordon-bleu homolog (mouse)	0.025
cps1	carbamoyl-phosphate synthase 1, mitochondrial	0.024
nkx2.3	NK2 transcription factor related 3	0.023
adipoql2	adiponectin, C1Q and collagen domain containing, like 2	0.022	Mouse
fgf8b	fibroblast growth factor 8 b	0.022
wnt9a	wingless-type MMTV integration site family, member 9A	0.022
wls	wntless homolog (Drosophila)	0.022
odz4	odd Oz/ten-m homolog 4	0.021
cdh17	cadherin 17, LI cadherin (liver-intestine)	0.021
foxd3	forkhead box D3	0.021
foxi3a	forkhead box I3a	0.021
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.020
eng1a	engrailed 1a	0.020
prdm16	PR domain containing 16	0.020
ccdc151	coiled-coil domain containing 151	0.020
hoxa1a	homeo box A1a	0.019
mef2ca	myocyte enhancer factor 2ca	0.019	Mouse
hhex	hematopoietically expressed homeobox	0.018
tp73	tumor protein p73	0.018
sox9a	SRY-box containing gene 9a	0.018
pax5	paired box gene 5	0.018
hoxb4a	homeo box B4a	0.017
vegfaa	vascular endothelial growth factor Aa	0.017
vsx2	visual system homeobox 2	0.017
fzd8a	frizzled homolog 8a	0.017
tmem88a	transmembrane protein 88 a	0.016
znf703	zinc finger protein 703	0.016
edn1	endothelin 1	0.016
fgf8a	fibroblast growth factor 8 a	0.016
her6	hairy-related 6	0.016
sox2	SRY-box containing gene 2	0.016
capns1a	calpain, small subunit 1 a	0.015
foxi3b	forkhead box I3b	0.015
neurod4	neurogenic differentiation 4	0.015
barx2	BarH-like homeobox 2	0.015
jag2	jagged 2	0.015
ctsl1b	cathepsin L, 1 b	0.015
mafl	v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L	0.015
barx1	BarH-like homeobox 1	0.014
rela	v-rel reticuloendotheliosis viral oncogene homolog A	0.014
ism1	isthmin 1	0.014
kirrelb	kin of IRRE like b	0.014
pou4f2	POU domain, class 4, transcription factor 2	0.014
ndr2	nodal-related 2	0.014
grhl2a	grainyhead-like 2a (Drosophila)	0.014
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.013
glra4a	glycine receptor, alpha 4a	0.013
her12	hairy-related 12	0.013
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.013
atoh7	atonal homolog 7	0.013
krt4	keratin 4	0.012
tfeb	transcription factor EB	0.012
tfec	transcription factor EC	0.012
cited3	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 3	0.012
emx3	empty spiracles homeobox 3	0.012
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.012
nrarpa	notch-regulated ankyrin repeat protein a	0.012
efnb3b	ephrin B3b	0.012
grem2	gremlin 2, cysteine knot superfamily	0.012
ptch2	patched 2	0.012
fsta	follistatin a	0.012
gdnf	glial cell derived neurotrophic factor	0.012
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.012
wu:fv91b12	wu:fv91b12	0.012
gsc	goosecoid	0.011
foxn1	forkhead box N1	0.011
erf	Ets2 repressor factor	0.011
pitx2	paired-like homeodomain transcription factor 2	0.011
dnmt8	DNA (cytosine-5-)-methyltransferase 8	0.011
mib	mind bomb	0.011
cdh2	cadherin 2, neuronal	0.010
cx39.9	connexin 39.9	0.010
ins	preproinsulin	0.010
neo1	neogenin 1	0.010
atic	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	0.010
slc12a10.2	solute carrier family 12 (sodium/potassium/chloride transporters), member 10.2	0.010
flot1	flotillin 1	0.010
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.010