IMP

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Danio rerio

4 genes annotated in zebrafish

axon midline choice point recognition

The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "axon midline choice point recognition"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "axon midline choice point recognition" (in gray)

Name	Description	Probability	Func Analog Organism
robo3	roundabout homolog 3	0.974
robo2	roundabout homolog 2	0.948
lhx2b	LIM homeobox 2b	0.822
robo1	roundabout homolog 1	0.661	Zebrafish Mouse Rat Fly
slit1a	slit homolog 1a (Drosophila)	0.586	Fly
gsna	gelsolin a	0.408
foxp2	forkhead box P2	0.402
cntn2	contactin 2	0.358
slit3	slit (Drosophila) homolog 3	0.264	Fly
gria3a	glutamate receptor, ionotropic, AMPA 3a	0.241
wnt3	wingless-type MMTV integration site family, member 3	0.229
tbx2b	T-box 2b	0.213
camkvb	CaM kinase-like vesicle-associated b	0.182
ntn1a	netrin 1a	0.172
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.158
irx1a	iroquois homeobox protein 1, a	0.148
slit1b	slit homolog 1b (Drosophila)	0.144	Fly
unc5b	unc-5 homolog B (C. elegans)	0.143
mbnl2	muscleblind-like 2 (Drosophila)	0.141
flot1	flotillin 1	0.138
neo1	neogenin 1	0.138	Fly
nrp1a	neuropilin 1a	0.133
dpysl2b	dihydropyrimidinase-like 2b	0.128
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.108
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.106
gria1a	glutamate receptor, ionotropic, AMPA 1a	0.102
sp8a	sp8 transcription factor a	0.101
dlx2a	distal-less homeobox gene 2a	0.099
cntfr	ciliary neurotrophic factor receptor	0.097
slit2	slit (Drosophila) homolog 2	0.096	Fly
adarb1	adenosine deaminase, RNA-specific, B1	0.096
gria1b	glutamate receptor, ionotropic, AMPA 1b	0.089
gria4b	glutamate receptor, ionotropic, AMPA 4b	0.087
phox2a	paired-like homeobox 2a	0.084
gria3b	glutamate receptor, ionotrophic, AMPA 3b	0.081
gria4a	glutamate receptor, ionotropic, AMPA 4a	0.079
evx1	even-skipped homeobox 1	0.078
cd99l2	CD99 antigen-like 2	0.078
aplp2	amyloid beta (A4) precursor-like protein 2	0.075
isl2a	islet2a	0.074
coe2	coe2	0.074
id:ibd2808	id:ibd2808	0.067
im:7154036	im:7154036	0.066
dcc	deleted in colorectal carcinoma	0.065
pax6a	paired box gene 6a	0.064
dla	deltaA	0.062
sulf1	sulfatase 1	0.058
kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.058
scrt1a	scratch homolog 1, zinc finger protein a (Drosophila)	0.055
hoxa13a	homeo box A13a	0.054
auts2	autism susceptibility candidate 2	0.054
kal1a	Kallmann syndrome 1a sequence	0.053
ptprfb	protein tyrosine phosphatase, receptor type, f, b	0.050
axin1	axin 1	0.048
ebf3	early B-cell factor 3	0.046
slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.045
insm1a	insulinoma-associated 1a	0.044
boc	brother of CDO	0.042
fgfr3	fibroblast growth factor receptor 3	0.042
barhl2	BarH-like 2	0.042
emx2	empty spiracles homeobox 2	0.042
tyrp1b	tyrosinase-related protein 1b	0.041
sox21b	SRY-box containing gene 21 b	0.041
rad21	RAD21 homolog (S. pombe)	0.040
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.039
fktn	fukutin	0.039
sema3ga	semaphorin 3ga	0.039
zmiz1	zinc finger, MIZ-type containing 1	0.038
emx3	empty spiracles homeobox 3	0.038
elmo1	engulfment and cell motility 1 (ced-12 homolog, C. elegans)	0.037
tcf12	transcription factor 12	0.036
cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.035
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.034
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.033
hs6st1a	heparan sulfate 6-O-sulfotransferase 1a	0.033
tac1	tachykinin 1	0.032
irx2a	iroquois homeobox protein 2, a	0.032
nrp2b	neuropilin 2b	0.032
znf503	zinc finger protein 503	0.031
kdelr3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.031
scrt1b	scratch homolog 1, zinc finger protein b (Drosophila)	0.031
igfbp5a	insulin-like growth factor binding protein 5a	0.029
slc17a6b	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b	0.029
jag2	jagged 2	0.029
kbp	kif1-binding protein	0.028
trim8	tripartite motif-containing 8	0.028
dopey1	dopey family member 1	0.027
atl1	atlastin GTPase 1	0.026
hs3st3b1b	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b	0.025
plxna4	plexin A4	0.025	Fly
plxna3	plexin A3	0.025	Fly
met	met proto-oncogene (hepatocyte growth factor receptor)	0.024
sc:d0316	sc:d0316	0.024
ttc28	tetratricopeptide repeat domain 28	0.024
sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.023
pcdh19	protocadherin 19	0.023
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.023
LOC555504	novel protocadherin protein	0.023
lrrtm1	leucine rich repeat transmembrane neuronal 1	0.023
pcdh10b	protocadherin 10b	0.022
hs6st1b	heparan sulfate 6-O-sulfotransferase 1b	0.022
gria2a	glutamate receptor, ionotropic, AMPA 2a	0.022
skia	nuclear oncoprotein skia	0.022
six3a	sine oculis homeobox homolog 3a	0.022
fgfr2	fibroblast growth factor receptor 2	0.021
pofut2	protein O-fucosyltransferase 2	0.021
midn	midnolin	0.021
alcama	activated leukocyte cell adhesion molecule a	0.020
sox10	SRY-box containing gene 10	0.020
rhoua	ras homolog gene family, member Ua	0.020
plxnb2b	plexin b2b	0.020
mycbp2	MYC binding protein 2	0.020
pdzrn3	PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3	0.020
mbtps1	membrane-bound transcription factor protease, site 1	0.018
chrna6	cholinergic receptor, nicotinic, alpha 6	0.018
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.018
pcdh7	protocadherin 7	0.018
sec23a	Sec23 homolog A (S. cerevisiae)	0.018
mab21l2	mab-21-like 2	0.018
tfr1b	transferrin receptor 1b	0.018
ptger4a	prostaglandin E receptor 4 (subtype EP4) a	0.017
atoh7	atonal homolog 7	0.017
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.017
nr2f1b	nuclear receptor subfamily 2, group F, member 1b	0.017
polb	polymerase (DNA directed), beta	0.017
axin2	axin 2 (conductin, axil)	0.017
LOC100331502	melanopsin-B-like	0.017
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.017
pik3r2	phosphoinositide-3-kinase, regulatory subunit, polypeptide 2	0.017
epb4.1l4	erythrocyte protein band 4.1-like 4	0.017
vcanb	versican b	0.017
zic5	zic family member 5 (odd-paired homolog, Drosophila)	0.017
im:7137555	im:7137555	0.017
tpp1	tripeptidyl peptidase I	0.017
si:dkeyp-68f6.1	si:dkeyp-68f6.1	0.016
dzip1	DAZ interacting protein 1	0.016
fgfr1b	fibroblast growth factor receptor 1b	0.016
si:dkey-20n3.1	si:dkey-20n3.1	0.016
olig2	oligodendrocyte lineage transcription factor 2	0.016
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.015
rhoub	ras homolog gene family, member Ub	0.015
bcar1	breast cancer anti-estrogen resistance 1	0.015
hoxc13b	homeo box C13b	0.015
postn	periostin, osteoblast specific factor	0.015
smg7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.015
igf1rb	insulin-like growth factor 1b receptor	0.015
fut10	fucosyltransferase 10	0.015
acot11a	acyl-CoA thioesterase 11a	0.014
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.014
tgfbi	transforming growth factor, beta-induced	0.014
spna2	spectrin alpha 2	0.014
lingo1b	leucine rich repeat and Ig domain containing 1b	0.014
antxr1	anthrax toxin receptor 1	0.014
nr2f1a	nuclear receptor subfamily 2, group F, member 1a	0.014
si:dkeyp-51f12.4	si:dkeyp-51f12.4	0.014
loxl2b	lysyl oxidase-like 2b	0.014
nlgn4b	neuroligin 4b	0.014
si:ch211-216l23.1	si:ch211-216l23.1	0.013
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.013
meis2.1	myeloid ecotropic viral integration site 2.1	0.013
zeb2a	zinc finger E-box binding homeobox 2a	0.013
hif1ab	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b	0.013
ptges	prostaglandin E synthase	0.013
fkbp10	FK506 binding protein 10	0.013
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.013
cdh6	cadherin 6	0.013
zgc:114181	zgc:114181	0.013
si:dkeyp-22b2.3	si:dkeyp-22b2.3	0.013
zgc:122977	zgc:122977	0.013
plekhg5a	pleckstrin homology domain containing, family G (with RhoGef domain) member 5a	0.012
spon1b	spondin 1b	0.012
il6st	interleukin 6 signal transducer	0.012
ptn	pleiotrophin	0.012
col9a1	collagen, type IX, alpha 1	0.012
dnm2l	dynamin2-like	0.012
top2b	topoisomerase (DNA) II beta	0.012
LOC100330345	utrophin-like	0.012
gng13a	guanine nucleotide binding protein (G protein), gamma 13a	0.011
fzd7a	frizzled homolog 7a	0.011
mmp15a	matrix metallopeptidase 15a	0.011
apob	apolipoprotein B	0.011
si:dkeyp-104h9.6	si:dkeyp-104h9.6	0.011
otpa	orthopedia homolog a	0.011
trpa1b	transient receptor potential cation channel, subfamily A, member 1b	0.011
olfm2	olfactomedin 2	0.011
slc35c1	solute carrier family 35, member C1	0.011
zgc:114199	zgc:114199	0.011
slc16a10	solute carrier family 16, member 10 (aromatic amino acid transporter)	0.011
hoxc5a	homeo box C5a	0.011
ctnnb2	catenin, beta 2	0.011
LOC556453	zinc finger homeobox protein 4-like	0.011
actn1	actinin, alpha 1	0.011
yap1	Yes-associated protein 1	0.011
sp4	sp4 transcription factor	0.011
c1qtnf5	C1q and tumor necrosis factor related protein 5	0.011
lingo1a	leucine rich repeat and Ig domain containing 1a	0.010
lepre1	Lepre1 protein	0.010
si:ch211-258f14.6	si:ch211-258f14.6	0.010
gli2a	GLI-Kruppel family member GLI2a	0.010
znf536	zinc finger protein 536	0.010
zbtb16a	zinc finger and BTB domain containing 16a	0.010
hibadha	3-hydroxyisobutyrate dehydrogenase a	0.010
sp9	sp9 transcription factor	0.010
pou3f3b	POU class 3 homeobox 3b	0.010
st8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	0.010
sulf2l	sulfatase 2, like	0.010
myo10l1	myosin X-like 1	0.010
cabin1	calcineurin binding protein 1	0.010
and3	actinodin3	0.010