Process View
The network for 'proline transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| PICK1 | protein interacting with PRKCA 1 | 0.904 | |
| DRD2 | dopamine receptor D2 | 0.849 | |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.504 | |
| SLC7A5 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 0.332 | |
| AARS | alanyl-tRNA synthetase | 0.310 | |
| SLC3A2 | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 0.287 | |
| GARS | glycyl-tRNA synthetase | 0.253 | |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.181 | |
| YARS | tyrosyl-tRNA synthetase | 0.175 | |
| MARS | methionyl-tRNA synthetase | 0.139 | |
| TPPP | tubulin polymerization promoting protein | 0.117 | |
| USP50 | ubiquitin specific peptidase 50 | 0.078 | |
| TRIB3 | tribbles homolog 3 (Drosophila) | 0.071 | |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.068 | |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 0.066 | |
| MPDU1 | mannose-P-dolichol utilization defect 1 | 0.064 | |
| CARS | cysteinyl-tRNA synthetase | 0.056 | |
| STX1A | syntaxin 1A (brain) | 0.054 | |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | 0.042 | |
| PRLHR | prolactin releasing hormone receptor | 0.039 | |
| HYOU1 | hypoxia up-regulated 1 | 0.039 | |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.039 | |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.039 | |
| PHGDH | phosphoglycerate dehydrogenase | 0.036 | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.034 | |
| ADORA2A | adenosine A2a receptor | 0.033 | |
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.032 | |
| NEK6 | NIMA (never in mitosis gene a)-related kinase 6 | 0.032 | |
| SARS | seryl-tRNA synthetase | 0.030 | |
| PRODH2 | proline dehydrogenase (oxidase) 2 | 0.029 | |
| PSAT1 | phosphoserine aminotransferase 1 | 0.025 | |
| HMGA1 | high mobility group AT-hook 1 | 0.024 | |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 0.024 | |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | 0.023 | |
| SLC22A6 | solute carrier family 22 (organic anion transporter), member 6 | 0.023 | |
| PAX8 | paired box 8 | 0.022 | |
| SLC9A3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.021 | |
| MUC3A | mucin 3A, cell surface associated | 0.021 | |
| TM4SF5 | transmembrane 4 L six family member 5 | 0.017 | |
| CHAC1 | ChaC, cation transport regulator homolog 1 (E. coli) | 0.017 | |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 | 0.016 | |
| SLC17A1 | solute carrier family 17 (sodium phosphate), member 1 | 0.016 | |
| SLC34A1 | solute carrier family 34 (sodium phosphate), member 1 | 0.016 | |
| TUB | tubby homolog (mouse) | 0.016 | |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 | 0.016 | |
| HCRTR1 | hypocretin (orexin) receptor 1 | 0.015 | |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.015 | |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 0.015 | |
| EMX1 | empty spiracles homeobox 1 | 0.014 | |
| LTK | leukocyte receptor tyrosine kinase | 0.014 | |
| KCNJ5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.014 | |
| SLC17A7 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | 0.013 | |
| SLC7A11 | solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 | 0.013 | |
| GRM2 | glutamate receptor, metabotropic 2 | 0.013 | |
| SPTB | spectrin, beta, erythrocytic | 0.013 | |
| SLC7A4 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 | 0.013 | |
| SIX6 | SIX homeobox 6 | 0.013 | |
| UNC93A | unc-93 homolog A (C. elegans) | 0.013 | |
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 | 0.013 | |
| IRX4 | iroquois homeobox 4 | 0.012 | |
| RHO | rhodopsin | 0.012 | |
| SLC13A2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 | 0.012 | |
| MAG | myelin associated glycoprotein | 0.012 | |
| HNF1B | HNF1 homeobox B | 0.012 | |
| SHH | sonic hedgehog | 0.012 | |
| TMEM151A | transmembrane protein 151A | 0.012 | |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 | 0.012 | |
| POU4F2 | POU class 4 homeobox 2 | 0.012 | |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 0.012 | |
| CBS | cystathionine-beta-synthase | 0.011 | |
| RBP2 | retinol binding protein 2, cellular | 0.011 | |
| CYP11B2 | cytochrome P450, family 11, subfamily B, polypeptide 2 | 0.011 | |
| VEGFA | vascular endothelial growth factor A | 0.011 | |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.011 | |
| HSF1 | heat shock transcription factor 1 | 0.011 | |
| CNTN2 | contactin 2 (axonal) | 0.011 | |
| HTR2C | 5-hydroxytryptamine (serotonin) receptor 2C | 0.011 | |
| KLK6 | kallikrein-related peptidase 6 | 0.011 | |
| MLXIPL | MLX interacting protein-like | 0.011 | |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | 0.011 | |
| GJC2 | gap junction protein, gamma 2, 47kDa | 0.011 | |
| MYO16 | myosin XVI | 0.011 | |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.011 | |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | 0.010 | |
| EGR4 | early growth response 4 | 0.010 | |
| UNC5B | unc-5 homolog B (C. elegans) | 0.010 | |
| BEAN1 | brain expressed, associated with NEDD4, 1 | 0.010 | |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 0.010 | |
| CHP2 | calcineurin B homologous protein 2 | 0.010 | |
| AGXT | alanine-glyoxylate aminotransferase | 0.010 | |
| KCNC3 | potassium voltage-gated channel, Shaw-related subfamily, member 3 | 0.010 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 0.031 | |
| Cubn | cubilin (intrinsic factor-cobalamin receptor) | 0.028 | |
| Mep1a | meprin 1 alpha | 0.028 | |
| Slc22a6 | solute carrier family 22 (organic anion transporter), member 6 | 0.027 | |
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.022 | |
| Slc17a1 | solute carrier family 17 (sodium phosphate), member 1 | 0.022 | |
| Akr1c21 | aldo-keto reductase family 1, member C21 | 0.022 | |
| Slc22a2 | solute carrier family 22 (organic cation transporter), member 2 | 0.021 | |
| Slc7a9 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 | 0.018 | |
| Dync1i1 | dynein cytoplasmic 1 intermediate chain 1 | 0.017 | |
| Slc12a1 | solute carrier family 12, member 1 | 0.017 | |
| Clcnka | chloride channel Ka | 0.015 | |
| Dao | D-amino acid oxidase | 0.013 | |
| Ltk | leukocyte tyrosine kinase | 0.012 | |
| Slc5a11 | solute carrier family 5 (sodium/glucose cotransporter), member 11 | 0.012 | |
| Slc6a18 | solute carrier family 6 (neurotransmitter transporter), member 18 | 0.011 | |
| Crym | crystallin, mu | 0.011 | |
| Tff1 | trefoil factor 1 | 0.011 | |
| Ngef | neuronal guanine nucleotide exchange factor | 0.011 | |
| Spns3 | spinster homolog 3 (Drosophila) | 0.011 | |
| Scg5 | secretogranin V | 0.010 | |
| Folr1 | folate receptor 1 (adult) | 0.010 | |
| 2410004A20Rik | RIKEN cDNA 2410004A20 gene | 0.010 | |
| Syn2 | synapsin II | 0.010 | |
| Pdzd3 | PDZ domain containing 3 | 0.010 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Rac2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.034 | |
| LOC689399 | hypothetical protein LOC689399 | 0.030 | |
| Ly86 | lymphocyte antigen 86 | 0.024 | |
| Fcer1g | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.019 | |
| Tyrobp | Tyro protein tyrosine kinase binding protein | 0.018 | |
| Pgam2 | phosphoglycerate mutase 2 (muscle) | 0.016 | |
| Smcp | sperm mitochondria-associated cysteine-rich protein | 0.016 | |
| Rpl8 | ribosomal protein L8 | 0.016 | |
| Pycard | PYD and CARD domain containing | 0.015 | |
| Asb9 | ankyrin repeat and SOCS box-containing 9 | 0.014 | |
| Slc6a2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | 0.014 | |
| Fcgr2a | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.013 | |
| Slc6a17 | solute carrier family 6 (neurotransmitter transporter), member 17 | 0.013 | |
| Akt2 | v-akt murine thymoma viral oncogene homolog 2 | 0.013 | |
| LOC171573 | spleen protein 1 precursor | 0.013 | |
| Rps15 | ribosomal protein S15 | 0.013 | |
| Laptm5 | lysosomal protein transmembrane 5 | 0.013 | |
| Gnb2l1 | guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 | 0.013 | |
| C5ar1 | complement component 5a receptor 1 | 0.013 | |
| Tlr7 | toll-like receptor 7 | 0.013 | |
| Arhgdib | Rho, GDP dissociation inhibitor (GDI) beta | 0.013 | |
| Col4a1 | collagen, type IV, alpha 1 | 0.013 | |
| Rpl28 | ribosomal protein L28 | 0.012 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.012 | |
| Il9r | interleukin 9 receptor | 0.012 | |
| Gpnmb | glycoprotein (transmembrane) nmb | 0.012 | |
| Arpc1b | actin related protein 2/3 complex, subunit 1B | 0.012 | |
| Fam65a | family with sequence similarity 65, member A | 0.012 | |
| C1qa | complement component 1, q subcomponent, A chain | 0.012 | |
| Dag1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.011 | |
| Cd53 | Cd53 molecule | 0.011 | |
| Arnt | aryl hydrocarbon receptor nuclear translocator | 0.011 | |
| LOC499782 | similar to 60S ribosomal protein L12 | 0.011 | |
| Ms4a6b | membrane-spanning 4-domains, subfamily A, member 6B | 0.011 | |
| RGD1309139 | similar to CG5435-PA | 0.011 | |
| Psg29 | pregnancy-specific glycoprotein 29 | 0.011 | |
| Racgap1 | Rac GTPase-activating protein 1 | 0.011 | |
| Met | met proto-oncogene | 0.011 | |
| Lcp1 | lymphocyte cytosolic protein 1 | 0.011 | |
| Fxyd5 | FXYD domain-containing ion transport regulator 5 | 0.011 | |
| Ttll3 | tubulin tyrosine ligase-like family, member 3 | 0.010 | |
| Tpm4 | tropomyosin 4 | 0.010 | |
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.010 | |
| Ceacam11 | carcinoembryonic antigen-related cell adhesion molecule 11 | 0.010 | |
| Plek | pleckstrin | 0.010 | |
| Cd37 | CD37 molecule | 0.010 | |
| Icos | inducible T-cell co-stimulator | 0.010 | |
| Flna | filamin A, alpha | 0.010 | |
| Phex | phosphate regulating endopeptidase homolog, X-linked | 0.010 |