The network for 'regulation of lymphocyte chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of lymphocyte chemotaxis

Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.

Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 1.000
CXCL9 chemokine (C-X-C motif) ligand 9 0.995
CCL4 chemokine (C-C motif) ligand 4 0.994
CCL5 chemokine (C-C motif) ligand 5 0.957
ABI2 abl-interactor 2 0.916
CCL8 chemokine (C-C motif) ligand 8 0.889
CXCL10 chemokine (C-X-C motif) ligand 10 0.884
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.853
CCL2 chemokine (C-C motif) ligand 2 0.840
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.839
CCL13 chemokine (C-C motif) ligand 13 0.766
SNX9 sorting nexin 9 0.711
CXCL11 chemokine (C-X-C motif) ligand 11 0.664
IL8 interleukin 8 0.648
IL6 interleukin 6 (interferon, beta 2) 0.639
CCR7 chemokine (C-C motif) receptor 7 0.613
IL1B interleukin 1, beta 0.552
PDIA3 protein disulfide isomerase family A, member 3 0.528
DPP4 dipeptidyl-peptidase 4 0.511
CCL19 chemokine (C-C motif) ligand 19 0.452
CCL22 chemokine (C-C motif) ligand 22 0.428
CCL7 chemokine (C-C motif) ligand 7 0.411
IDE insulin-degrading enzyme 0.363
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.343
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.309
IFNG interferon, gamma 0.305
CXCL3 chemokine (C-X-C motif) ligand 3 0.296
CXCL13 chemokine (C-X-C motif) ligand 13 0.284
CXCL2 chemokine (C-X-C motif) ligand 2 0.277
SPRR2A small proline-rich protein 2A 0.233
SNX33 sorting nexin 33 0.207
CD2 CD2 molecule 0.191
CXCR6 chemokine (C-X-C motif) receptor 6 0.183
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.158
VCAM1 vascular cell adhesion molecule 1 0.139
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.134
CCR4 chemokine (C-C motif) receptor 4 0.130
CCR1 chemokine (C-C motif) receptor 1 0.120
CCL3 chemokine (C-C motif) ligand 3 0.110
SH3D19 SH3 domain containing 19 0.109
CCL11 chemokine (C-C motif) ligand 11 0.104
IL7R interleukin 7 receptor 0.103
SH3PXD2A SH3 and PX domains 2A 0.102
DNM1 dynamin 1 0.094
IL2RB interleukin 2 receptor, beta 0.093
FPR3 formyl peptide receptor 3 0.091
ADAMDEC1 ADAM-like, decysin 1 0.089
CXCL5 chemokine (C-X-C motif) ligand 5 0.083
CCL20 chemokine (C-C motif) ligand 20 0.078
UBD ubiquitin D 0.078
TNF tumor necrosis factor 0.073
FZD1 frizzled homolog 1 (Drosophila) 0.067
RGS1 regulator of G-protein signaling 1 0.066
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.064
ADAM9 ADAM metallopeptidase domain 9 0.062
PTPRA protein tyrosine phosphatase, receptor type, A 0.055
CD83 CD83 molecule 0.054
SLAMF7 SLAM family member 7 0.045
SELE selectin E 0.044
TMEM30A transmembrane protein 30A 0.040
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.039
LAMP3 lysosomal-associated membrane protein 3 0.037
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.037
MATK megakaryocyte-associated tyrosine kinase 0.036
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.036
CPD carboxypeptidase D 0.035
IL2RG interleukin 2 receptor, gamma 0.034
TRAM1 translocation associated membrane protein 1 0.034
CD80 CD80 molecule 0.033
IGFBP3 insulin-like growth factor binding protein 3 0.032
IQGAP1 IQ motif containing GTPase activating protein 1 0.032
IRF4 interferon regulatory factor 4 0.030
LRP6 low density lipoprotein receptor-related protein 6 0.027
SEC23A Sec23 homolog A (S. cerevisiae) 0.027
CH25H cholesterol 25-hydroxylase 0.025
CXCR3 chemokine (C-X-C motif) receptor 3 0.025
IDO1 indoleamine 2,3-dioxygenase 1 0.024
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.024
BCAR1 breast cancer anti-estrogen resistance 1 0.023
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.023
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.022
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.022
INHBA inhibin, beta A 0.021
SLAMF8 SLAM family member 8 0.020
EBI3 Epstein-Barr virus induced 3 0.020
CLIC4 chloride intracellular channel 4 0.020
CD86 CD86 molecule 0.020
CD1B CD1b molecule 0.019
MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) 0.019
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.019
CCL17 chemokine (C-C motif) ligand 17 0.019
WISP1 WNT1 inducible signaling pathway protein 1 0.018
IL21R interleukin 21 receptor 0.018
CCR3 chemokine (C-C motif) receptor 3 0.018
XCL1 chemokine (C motif) ligand 1 0.018
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.018
IL18RAP interleukin 18 receptor accessory protein 0.017
CALR calreticulin 0.017
IL2RA interleukin 2 receptor, alpha 0.017
IL1A interleukin 1, alpha 0.016
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ccr2 chemokine (C-C motif) receptor 2 0.869
Ccl2 chemokine (C-C motif) ligand 2 0.702
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.691
Ccl3 chemokine (C-C motif) ligand 3 0.635
Tnf tumor necrosis factor 0.626
Ccr1 chemokine (C-C motif) receptor 1 0.530
Lta lymphotoxin A 0.453
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.356
Ifng interferon gamma 0.249
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.237
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.225
Cd40 CD40 antigen 0.210
Cxcl13 chemokine (C-X-C motif) ligand 13 0.163
Ccl8 chemokine (C-C motif) ligand 8 0.162
Ccl4 chemokine (C-C motif) ligand 4 0.152
Cxcr5 chemokine (C-X-C motif) receptor 5 0.138
C3ar1 complement component 3a receptor 1 0.111
Ccl12 chemokine (C-C motif) ligand 12 0.106
Ccl7 chemokine (C-C motif) ligand 7 0.095
Il1b interleukin 1 beta 0.084
Selp selectin, platelet 0.076
Cd44 CD44 antigen 0.071
Cd7 CD7 antigen 0.056
Fcgr1 Fc receptor, IgG, high affinity I 0.053
Folr2 folate receptor 2 (fetal) 0.046
Ccr5 chemokine (C-C motif) receptor 5 0.043
Pdcd1 programmed cell death 1 0.041
Batf basic leucine zipper transcription factor, ATF-like 0.040
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.040
Icos inducible T-cell co-stimulator 0.039
Ltb lymphotoxin B 0.039
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.038
Itgax integrin alpha X 0.035
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.034
Gzmk granzyme K 0.031
Mx2 myxovirus (influenza virus) resistance 2 0.029
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.029
Ccl22 chemokine (C-C motif) ligand 22 0.028
Gzmb granzyme B 0.027
Ubd ubiquitin D 0.027
Ccl17 chemokine (C-C motif) ligand 17 0.026
Fasl Fas ligand (TNF superfamily, member 6) 0.025
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.024
Sh2d2a SH2 domain protein 2A 0.024
Sfpi1 SFFV proviral integration 1 0.023
Gpr132 G protein-coupled receptor 132 0.022
Cd160 CD160 antigen 0.022
Il7 interleukin 7 0.022
Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8 0.021
Cd96 CD96 antigen 0.020
Btk Bruton agammaglobulinemia tyrosine kinase 0.019
Il12rb2 interleukin 12 receptor, beta 2 0.019
Ccr7 chemokine (C-C motif) receptor 7 0.019
Mmp12 matrix metallopeptidase 12 0.019
Mmp3 matrix metallopeptidase 3 0.019
Il1rn interleukin 1 receptor antagonist 0.018
Il18rap interleukin 18 receptor accessory protein 0.017
Sele selectin, endothelial cell 0.017
Cd8a CD8 antigen, alpha chain 0.017
Ch25h cholesterol 25-hydroxylase 0.017
Bdkrb1 bradykinin receptor, beta 1 0.017
Cxcr3 chemokine (C-X-C motif) receptor 3 0.017
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.016
Gzma granzyme A 0.016
Klrb1c killer cell lectin-like receptor subfamily B member 1C 0.015
Ctsw cathepsin W 0.014
Xcr1 chemokine (C motif) receptor 1 0.014
Efnb2 ephrin B2 0.014
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.014
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.013
Cd19 CD19 antigen 0.013
Cd3e CD3 antigen, epsilon polypeptide 0.013
Il10 interleukin 10 0.013
Socs1 suppressor of cytokine signaling 1 0.012
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.012
Ptgir prostaglandin I receptor (IP) 0.012
Il10ra interleukin 10 receptor, alpha 0.011
Slfn4 schlafen 4 0.011
Rapsn receptor-associated protein of the synapse 0.011
Cxcl10 chemokine (C-X-C motif) ligand 10 0.011
Il1a interleukin 1 alpha 0.011
Prdm1 PR domain containing 1, with ZNF domain 0.011
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.010
Ccl20 chemokine (C-C motif) ligand 20 0.010
Cx3cr1 chemokine (C-X3-C) receptor 1 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Il1b interleukin 1 beta 0.993
Ccl2 chemokine (C-C motif) ligand 2 0.939
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.932
Ccl4 chemokine (C-C motif) ligand 4 0.897
Cxcl10 chemokine (C-X-C motif) ligand 10 0.820
Ccl3 chemokine (C-C motif) ligand 3 0.793
Il1a interleukin 1 alpha 0.669
Gzmk granzyme K 0.480
Hpgds hematopoietic prostaglandin D synthase 0.413
Cxcl2 chemokine (C-X-C motif) ligand 2 0.402
Cd14 CD14 molecule 0.381
Fcer1a Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.352
Il6 interleukin 6 0.341
Sell selectin L 0.341
Prf1 perforin 1 (pore forming protein) 0.310
Mmp3 matrix metallopeptidase 3 0.275
Nkg7 natural killer cell group 7 sequence 0.273
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.272
Il2rb interleukin 2 receptor, beta 0.244
Ccl5 chemokine (C-C motif) ligand 5 0.241
Ccl20 chemokine (C-C motif) ligand 20 0.231
Reg3b regenerating islet-derived 3 beta 0.229
Mmp12 matrix metallopeptidase 12 0.222
Rgs1 regulator of G-protein signaling 1 0.215
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.192
Igsf6 immunoglobulin superfamily, member 6 0.180
Cd8a CD8a molecule 0.159
Gzmb granzyme B 0.152
Xcl1 chemokine (C motif) ligand 1 0.147
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.134
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.132
Ccl7 chemokine (C-C motif) ligand 7 0.131
Calcrl calcitonin receptor-like 0.130
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.129
Hck hemopoietic cell kinase 0.122
Has2 hyaluronan synthase 2 0.121
Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) 0.097
Ccr5 chemokine (C-C motif) receptor 5 0.090
Dnase1l3 deoxyribonuclease 1-like 3 0.085
Cd86 CD86 molecule 0.080
Tlr2 toll-like receptor 2 0.080
Stx11 syntaxin 11 0.080
Cd247 Cd247 molecule 0.068
Neurl3 neuralized homolog 3 (Drosophila) 0.068
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.067
Met met proto-oncogene 0.064
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.061
Il2rg interleukin 2 receptor, gamma 0.061
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.056
Icam1 intercellular adhesion molecule 1 0.056
LOC24906 RoBo-1 0.055
Cd69 Cd69 molecule 0.054
Ccl11 chemokine (C-C motif) ligand 11 0.052
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.052
Myoc myocilin 0.051
Slpi secretory leukocyte peptidase inhibitor 0.051
Nox4 NADPH oxidase 4 0.047
Plek pleckstrin 0.047
Clec2d C-type lectin domain family 2, member d 0.043
Cst7 cystatin F (leukocystatin) 0.042
Prkacb protein kinase, cAMP dependent, catalytic, beta 0.042
Tlr4 toll-like receptor 4 0.041
Myf6 myogenic factor 6 0.041
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.039
Cd72 Cd72 molecule 0.039
Sele selectin E 0.039
Ptprc protein tyrosine phosphatase, receptor type, C 0.038
Cubn cubilin (intrinsic factor-cobalamin receptor) 0.037
Tcf12 transcription factor 12 0.035
Adam2 ADAM metallopeptidase domain 2 0.035
Fosl1 fos-like antigen 1 0.035
Sh2d1a SH2 domain protein 1A 0.034
Ly6c Ly6-C antigen 0.034
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.033
Cd83 CD83 molecule 0.033
Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 0.032
Egr2 early growth response 2 0.032
Cpa3 carboxypeptidase A3, mast cell 0.031
Gimap4 GTPase, IMAP family member 4 0.031
Ubd ubiquitin D 0.031
Fcnb ficolin B 0.030
Rnf4 ring finger protein 4 0.030
Steap1 six transmembrane epithelial antigen of the prostate 1 0.030
Il1r2 interleukin 1 receptor, type II 0.030
Cldn7 claudin 7 0.030
Xiap X-linked inhibitor of apoptosis 0.029
Klre1 killer cell lectin-like receptor, family E, member 1 0.029
Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 0.029
Tfpi2 tissue factor pathway inhibitor 2 0.029
Dok2 docking protein 2 0.028
Nsf N-ethylmaleimide-sensitive factor 0.027
Ebi3 Epstein-Barr virus induced 3 0.026
Casp1 caspase 1 0.026
Prol1 proline rich, lacrimal 1 0.026
Gzma granzyme A 0.026
Ch25h cholesterol 25-hydroxylase 0.026
Serpinb2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.025
Arl5c ADP-ribosylation factor-like 5C 0.024
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.024
Picalm phosphatidylinositol binding clathrin assembly protein 0.024
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism