The network for 'regulation of viral genome replication' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of viral genome replication

Any process that modulates the frequency, rate or extent of viral genome replication.

Homo sapiens
Name Description Probability Func Analog Organism
ISG15 ISG15 ubiquitin-like modifier 0.999
IFITM1 interferon induced transmembrane protein 1 (9-27) 0.996
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.991
OAS1 2',5'-oligoadenylate synthetase 1, 40/46kDa 0.986
OASL 2'-5'-oligoadenylate synthetase-like 0.985
IFI44 interferon-induced protein 44 0.985
IFI44L interferon-induced protein 44-like 0.983
MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) 0.977
CXCL10 chemokine (C-X-C motif) ligand 10 0.968
MX2 myxovirus (influenza virus) resistance 2 (mouse) 0.956
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.939
CXCL3 chemokine (C-X-C motif) ligand 3 0.934
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.914
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.911
SP110 SP110 nuclear body protein 0.907
IFITM3 interferon induced transmembrane protein 3 (1-8U) 0.904
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.902
IFI6 interferon, alpha-inducible protein 6 0.896
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.891
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.822
PARP9 poly (ADP-ribose) polymerase family, member 9 0.810
IL8 interleukin 8 0.799
IFI27 interferon, alpha-inducible protein 27 0.764
CXCL2 chemokine (C-X-C motif) ligand 2 0.750
CCL8 chemokine (C-C motif) ligand 8 0.730
CCR5 chemokine (C-C motif) receptor 5 0.717
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.717
IFITM2 interferon induced transmembrane protein 2 (1-8D) 0.700
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.687
IRF7 interferon regulatory factor 7 0.677
IRF9 interferon regulatory factor 9 0.663
SP100 SP100 nuclear antigen 0.634
IFIH1 interferon induced with helicase C domain 1 0.621
DTX3L deltex 3-like (Drosophila) 0.585
CCL4 chemokine (C-C motif) ligand 4 0.583
IL6 interleukin 6 (interferon, beta 2) 0.544
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.481
XAF1 XIAP associated factor 1 0.468
CXCL11 chemokine (C-X-C motif) ligand 11 0.455
RSAD2 radical S-adenosyl methionine domain containing 2 0.433
CCL20 chemokine (C-C motif) ligand 20 0.335
IFI35 interferon-induced protein 35 0.323
DICER1 dicer 1, ribonuclease type III 0.322
CCL2 chemokine (C-C motif) ligand 2 0.293
BST2 bone marrow stromal cell antigen 2 0.292
DPP4 dipeptidyl-peptidase 4 0.289
CXCL9 chemokine (C-X-C motif) ligand 9 0.277
PLSCR1 phospholipid scramblase 1 0.257
CXCL5 chemokine (C-X-C motif) ligand 5 0.249
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.231
STAT1 signal transducer and activator of transcription 1, 91kDa 0.225
CCL5 chemokine (C-C motif) ligand 5 0.220
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 0.211
RBM8A RNA binding motif protein 8A 0.210
HERC5 hect domain and RLD 5 0.205
HNF4A hepatocyte nuclear factor 4, alpha 0.200
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.196
IDE insulin-degrading enzyme 0.190
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.186
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.184
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.184
PARP14 poly (ADP-ribose) polymerase family, member 14 0.181
LY6E lymphocyte antigen 6 complex, locus E 0.178
IL1B interleukin 1, beta 0.175
SAMD9L sterile alpha motif domain containing 9-like 0.168
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.163
XAB2 XPA binding protein 2 0.161
ADAR adenosine deaminase, RNA-specific 0.156
PARP12 poly (ADP-ribose) polymerase family, member 12 0.144
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.140
EPSTI1 epithelial stromal interaction 1 (breast) 0.133
MSH6 mutS homolog 6 (E. coli) 0.124
USP18 ubiquitin specific peptidase 18 0.122
ZNFX1 zinc finger, NFX1-type containing 1 0.121
CCL13 chemokine (C-C motif) ligand 13 0.118
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.117
SRPK1 SRSF protein kinase 1 0.109
HLA-F major histocompatibility complex, class I, F 0.101
SAMD9 sterile alpha motif domain containing 9 0.099
PRMT6 protein arginine methyltransferase 6 0.097
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.093
CXCL13 chemokine (C-X-C motif) ligand 13 0.091
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.089
ICAM1 intercellular adhesion molecule 1 0.085
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.084
IDO1 indoleamine 2,3-dioxygenase 1 0.083
PI3 peptidase inhibitor 3, skin-derived 0.081
TMEM173 transmembrane protein 173 0.080
RNPS1 RNA binding protein S1, serine-rich domain 0.078
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.075
THOC4 THO complex 4 0.073
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.073
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.072
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.071
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.068
CCL3 chemokine (C-C motif) ligand 3 0.067
PRIC285 peroxisomal proliferator-activated receptor A interacting complex 285 0.064
RAD23B RAD23 homolog B (S. cerevisiae) 0.062
IFNG interferon, gamma 0.062
XPO1 exportin 1 (CRM1 homolog, yeast) 0.062
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
H Hairless 0.084
Rac1 CG2248 gene product from transcript CG2248-RA 0.081
Rab11 Rab-protein 11 0.056
dx deltex 0.051
mit(1)15 mitotic 15 0.049
Vang Van Gogh 0.044
ttk tramtrack 0.039
numb CG3779 gene product from transcript CG3779-RB 0.036
N Notch 0.035
Hop Hsp70/Hsp90 organizing protein homolog 0.033
ftz-f1 ftz transcription factor 1 0.033
gammaTub23C gamma-Tubulin at 23C 0.032
bcd bicoid 0.031
CG11015 CG11015 gene product from transcript CG11015-RA 0.030
Gp150 CG5820 gene product from transcript CG5820-RA 0.029
phl pole hole 0.028
Rho1 CG8416 gene product from transcript CG8416-RB 0.028
l(2)gd1 lethal (2) giant discs 1 0.027
G-oalpha47A G protein oalpha 47A 0.026
wg wingless 0.025
Dl Delta 0.024
fz frizzled 0.024
Aats-asp Aspartyl-tRNA synthetase 0.023
CG9172 CG9172 gene product from transcript CG9172-RA 0.023
pygo pygopus 0.022
R Roughened 0.022
zip zipper 0.022
CG3560 CG3560 gene product from transcript CG3560-RA 0.021
mbc myoblast city 0.020
aop anterior open 0.020
bs blistered 0.020
neur neuralized 0.020
CG4751 CG4751 gene product from transcript CG4751-RA 0.020
CG8928 CG8928 gene product from transcript CG8928-RA 0.020
CG11076 CG11076 gene product from transcript CG11076-RB 0.019
CG6459 CG6459 gene product from transcript CG6459-RA 0.019
Vha36 CG8186 gene product from transcript CG8186-RA 0.019
RecQ4 CG7487 gene product from transcript CG7487-RA 0.019
l(2)03709 lethal (2) 03709 0.018
Bx Beadex 0.018
rhea CG6831 gene product from transcript CG6831-RA 0.018
Syx7 Syntaxin 7 0.017
ifc infertile crescent 0.017
Trl Trithorax-like 0.016
nos nanos 0.016
fu fused 0.016
dos daughter of sevenless 0.016
dia diaphanous 0.016
CG9350 CG9350 gene product from transcript CG9350-RA 0.016
levy CG17280 gene product from transcript CG17280-RA 0.015
dpp decapentaplegic 0.015
rl rolled 0.015
CG18292 CG18292 gene product from transcript CG18292-RA 0.015
sqh spaghetti squash 0.015
fra frazzled 0.015
Fcp1 CG12252 gene product from transcript CG12252-RA 0.015
osa CG7467 gene product from transcript CG7467-RD 0.015
puc puckered 0.015
mam mastermind 0.014
Egfr Epidermal growth factor receptor 0.014
nkd naked cuticle 0.014
CG14235 CG14235 gene product from transcript CG14235-RA 0.014
CG10664 CG10664 gene product from transcript CG10664-RB 0.014
ATPsyn-gamma ATP synthase-gamma chain 0.014
lgs legless 0.014
sbr small bristles 0.013
spin spinster 0.013
corto CG2530 gene product from transcript CG2530-RA 0.013
CG18624 CG18624 gene product from transcript CG18624-RC 0.013
pnut peanut 0.013
CG7597 CG7597 gene product from transcript CG7597-RB 0.013
CG17259 CG17259 gene product from transcript CG17259-RA 0.013
La La autoantigen-like 0.013
CG3214 CG3214 gene product from transcript CG3214-RB 0.013
CG5703 CG5703 gene product from transcript CG5703-RA 0.013
shi shibire 0.013
mtacp1 mitochondrial acyl carrier protein 1 0.013
CG3192 CG3192 gene product from transcript CG3192-RA 0.012
l(1)dd4 lethal (1) discs degenerate 4 0.012
CG4769 CG4769 gene product from transcript CG4769-RA 0.012
Crc Calreticulin 0.012
CG5859 CG5859 gene product from transcript CG5859-RA 0.012
ND23 NADH:ubiquinone reductase 23kD subunit precursor 0.012
L Lobe 0.012
kuz kuzbanian 0.012
Antp Antennapedia 0.012
bun bunched 0.012
Sec61gamma CG14214 gene product from transcript CG14214-RA 0.012
en engrailed 0.012
l(3)neo18 lethal (3) neo18 0.012
trol terribly reduced optic lobes 0.012
MESR4 Misexpression suppressor of ras 4 0.011
sgg shaggy 0.011
didum dilute class unconventional myosin 0.011
CG9306 CG9306 gene product from transcript CG9306-RA 0.011
lqf liquid facets 0.011
E(z) Enhancer of zeste 0.011
bys by S6 0.011
eya eyes absent 0.011
CG3321 CG3321 gene product from transcript CG3321-RC 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.905
Irf7 interferon regulatory factor 7 0.812
Usp18 ubiquitin specific peptidase 18 0.802
Rtp4 receptor transporter protein 4 0.798
Rsad2 radical S-adenosyl methionine domain containing 2 0.714
Irf9 interferon regulatory factor 9 0.655
Oasl2 2'-5' oligoadenylate synthetase-like 2 0.649
Trim30a tripartite motif-containing 30A 0.639
Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 0.623
Uba7 ubiquitin-like modifier activating enzyme 7 0.598
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.535
Ifi44 interferon-induced protein 44 0.525
Ifi203 interferon activated gene 203 0.463
Isg15 ISG15 ubiquitin-like modifier 0.452
Gbp7 guanylate binding protein 7 0.401
Irgm2 immunity-related GTPase family M member 2 0.390
Irgm1 immunity-related GTPase family M member 1 0.385
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.384
Zbp1 Z-DNA binding protein 1 0.346
Igtp interferon gamma induced GTPase 0.282
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.248
Parp14 poly (ADP-ribose) polymerase family, member 14 0.239
Trim30d tripartite motif-containing 30D 0.227
Oas3 2'-5' oligoadenylate synthetase 3 0.211
Mx1 myxovirus (influenza virus) resistance 1 0.198
Oas1b 2'-5' oligoadenylate synthetase 1B 0.166
Ifih1 interferon induced with helicase C domain 1 0.166
Mx2 myxovirus (influenza virus) resistance 2 0.161
Oas2 2'-5' oligoadenylate synthetase 2 0.140
Tor3a torsin family 3, member A 0.139
Stat2 signal transducer and activator of transcription 2 0.129
Oasl1 2'-5' oligoadenylate synthetase-like 1 0.128
Gbp3 guanylate binding protein 3 0.123
Stat1 signal transducer and activator of transcription 1 0.116
Parp9 poly (ADP-ribose) polymerase family, member 9 0.115
Ifi47 interferon gamma inducible protein 47 0.110
Trim25 tripartite motif-containing 25 0.109
Slfn4 schlafen 4 0.101
D14Ertd668e DNA segment, Chr 14, ERATO Doi 668, expressed 0.096
Ifi35 interferon-induced protein 35 0.093
Iigp1 interferon inducible GTPase 1 0.085
Trim21 tripartite motif-containing 21 0.085
Cmpk2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.084
Oas1a 2'-5' oligoadenylate synthetase 1A 0.080
Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein 0.074
Ube2l6 ubiquitin-conjugating enzyme E2L 6 0.069
Dtx3l deltex 3-like (Drosophila) 0.063
Lgals9 lectin, galactose binding, soluble 9 0.058
Gbp2 guanylate binding protein 2 0.058
Trim12a tripartite motif-containing 12A 0.056
Tgtp2 T-cell specific GTPase 2 0.052
BC006779 cDNA sequence BC006779 0.049
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.046
Ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.041
Tmem106a transmembrane protein 106A 0.040
Ifi27l2a interferon, alpha-inducible protein 27 like 2A 0.037
Samd9l sterile alpha motif domain containing 9-like 0.036
Bst2 bone marrow stromal cell antigen 2 0.036
Parp12 poly (ADP-ribose) polymerase family, member 12 0.035
Herc6 hect domain and RLD 6 0.035
Xaf1 XIAP associated factor 1 0.035
Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 0.033
Gbp6 guanylate binding protein 6 0.032
Epsti1 epithelial stromal interaction 1 (breast) 0.029
Plac8 placenta-specific 8 0.026
Trim34a tripartite motif-containing 34A 0.026
Ly6a lymphocyte antigen 6 complex, locus A 0.026
Parp10 poly (ADP-ribose) polymerase family, member 10 0.025
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.024
Cxcl10 chemokine (C-X-C motif) ligand 10 0.024
Eef1a1 eukaryotic translation elongation factor 1 alpha 1 0.023
Trim12c tripartite motif-containing 12C 0.023
Gbp10 guanylate-binding protein 10 0.023
Traf3 TNF receptor-associated factor 3 0.022
Sp100 nuclear antigen Sp100 0.022
Mndal myeloid nuclear differentiation antigen like 0.021
H2-T24 histocompatibility 2, T region locus 24 0.020
Igh immunoglobulin heavy chain complex 0.017
Ifit2 interferon-induced protein with tetratricopeptide repeats 2 0.017
Tapbp TAP binding protein 0.017
H2-M3 histocompatibility 2, M region locus 3 0.016
Ifitm3 interferon induced transmembrane protein 3 0.016
Nup85 nucleoporin 85 0.015
Gm12185 predicted gene 12185 0.015
Rnf135 ring finger protein 135 0.015
Mfn2 mitofusin 2 0.015
Cd274 CD274 antigen 0.014
Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 0.014
Apol9a apolipoprotein L 9a 0.014
Txnip thioredoxin interacting protein 0.014
Fcgr4 Fc receptor, IgG, low affinity IV 0.014
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.014
Hsph1 heat shock 105kDa/110kDa protein 1 0.014
Nlrc5 NLR family, CARD domain containing 5 0.013
Safb scaffold attachment factor B 0.013
Tcrd T-cell receptor delta chain 0.013
Slfn8 schlafen 8 0.012
Erap1 endoplasmic reticulum aminopeptidase 1 0.012
Ly6e lymphocyte antigen 6 complex, locus E 0.012
Lcn2 lipocalin 2 0.012
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.070
Irf7 interferon regulatory factor 7 0.034
Oas1a 2'-5' oligoadenylate synthetase 1A 0.031
Usp18 ubiquitin specific peptidase 18 0.027
Mx1 myxovirus (influenza virus) resistance 1 0.023
Dynll1 dynein light chain LC8-type 1 0.017
Oasl 2'-5'-oligoadenylate synthetase-like 0.017
Slc25a5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.015
Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein 0.013
Sub1 SUB1 homolog (S. cerevisiae) 0.012
Isg15 ISG15 ubiquitin-like modifier 0.012
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.011
RT1-S3 RT1 class Ib, locus S3 0.011
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.011
Mx2 myxovirus (influenza virus) resistance 2 0.011
Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 0.011
Timp1 TIMP metallopeptidase inhibitor 1 0.010
H3f3b H3 histone, family 3B 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism