The network for 'acetylcholine transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

acetylcholine transport

The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.

Mus musculus
Name Description Probability Func Analog Organism
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 0.996
Chrna9 cholinergic receptor, nicotinic, alpha polypeptide 9 0.995
Dtna dystrobrevin alpha 0.994
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.990
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.983
Kif5a kinesin family member 5A 0.943
Dmd dystrophin, muscular dystrophy 0.936
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.915
Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 0.913
Thrb thyroid hormone receptor beta 0.900
Thra thyroid hormone receptor alpha 0.880
Dtnbp1 dystrobrevin binding protein 1 0.728
Rapsn receptor-associated protein of the synapse 0.710
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.689
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.669
Rac1 RAS-related C3 botulinum substrate 1 0.645
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.643
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.626
Cav3 caveolin 3 0.551
Cbl Casitas B-lineage lymphoma 0.506
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.483
Nos1 nitric oxide synthase 1, neuronal 0.457
Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.436
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.425
Rho rhodopsin 0.420
Cacnb4 calcium channel, voltage-dependent, beta 4 subunit 0.412
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.381
Tmed8 transmembrane emp24 domain containing 8 0.378
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.372
Hcn3 hyperpolarization-activated, cyclic nucleotide-gated K+ 3 0.371
Mast1 microtubule associated serine/threonine kinase 1 0.349
Ache acetylcholinesterase 0.347
Ryr1 ryanodine receptor 1, skeletal muscle 0.340
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.337
Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) 0.311
Bsn bassoon 0.309
Mybph myosin binding protein H 0.298
Lpar5 lysophosphatidic acid receptor 5 0.293
Homer1 homer homolog 1 (Drosophila) 0.273
Chrna10 cholinergic receptor, nicotinic, alpha polypeptide 10 0.259
Has1 hyaluronan synthase1 0.235
Ptprn2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.232
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.225
AI118078 expressed sequence AI118078 0.221
Aplp2 amyloid beta (A4) precursor-like protein 2 0.212
Adcy4 adenylate cyclase 4 0.208
Tulp1 tubby like protein 1 0.206
Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit 0.203
Dnajb5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.201
Dynlt1b dynein light chain Tctex-type 1D 0.199
Sntb1 syntrophin, basic 1 0.194
Tbpl2 TATA box binding protein like 2 0.193
Duox2 dual oxidase 2 0.193
Musk muscle, skeletal, receptor tyrosine kinase 0.191
Kcnk4 potassium channel, subfamily K, member 4 0.186
Psap prosaposin 0.183
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.177
Plxna1 plexin A1 0.171
Htr5a 5-hydroxytryptamine (serotonin) receptor 5A 0.164
Grid1 glutamate receptor, ionotropic, delta 1 0.160
Eras ES cell-expressed Ras 0.157
Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 0.153
Ddr2 discoidin domain receptor family, member 2 0.153
Scn7a sodium channel, voltage-gated, type VII, alpha 0.147
Zfp358 zinc finger protein 358 0.146
Snta1 syntrophin, acidic 1 0.146
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) 0.145
Spna2 spectrin alpha 2 0.144
Gzmm granzyme M (lymphocyte met-ase 1) 0.143
Sphk1 sphingosine kinase 1 0.135
Scgn secretagogin, EF-hand calcium binding protein 0.135
Pitx3 paired-like homeodomain transcription factor 3 0.129
Scd2 stearoyl-Coenzyme A desaturase 2 0.126
Per3 period homolog 3 (Drosophila) 0.123
Cldn26 claudin 26 0.118
Gprin1 G protein-regulated inducer of neurite outgrowth 1 0.116
Nxnl2 nucleoredoxin-like 2 0.116
Mc3r melanocortin 3 receptor 0.115
Pde6c phosphodiesterase 6C, cGMP specific, cone, alpha prime 0.113
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.112
Omp olfactory marker protein 0.112
Aff2 AF4/FMR2 family, member 2 0.112
Nxnl1 nucleoredoxin-like 1 0.109
Plcb1 phospholipase C, beta 1 0.109
Scn8a sodium channel, voltage-gated, type VIII, alpha 0.109
Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 0.109
Gpr12 G-protein coupled receptor 12 0.109
Sphk2 sphingosine kinase 2 0.108
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.108
Slc27a4 solute carrier family 27 (fatty acid transporter), member 4 0.108
Zfr2 zinc finger RNA binding protein 2 0.108
Spry4 sprouty homolog 4 (Drosophila) 0.107
Xiap X-linked inhibitor of apoptosis 0.106
Aip aryl-hydrocarbon receptor-interacting protein 0.105
Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 0.105
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.104
Myog myogenin 0.103
Sag retinal S-antigen 0.101
Fgf13 fibroblast growth factor 13 0.101
Pvr poliovirus receptor 0.099
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
slo-1 Protein SLO-1 0.441
egl-15 Protein EGL-15 0.201
gar-3 Protein GAR-3 0.126
F32B5.7 Protein F32B5.7 0.123
magu-4 Protein MAGU-4 0.117
ist-1 Protein IST-1 0.115
pgal-1 Protein PGAL-1 0.095
dyb-1 Protein DYB-1 0.093
goa-1 Protein GOA-1 0.074
arc-1 Protein ARC-1 0.071
itr-1 Protein ITR-1 0.071
unc-36 Protein UNC-36 0.069
egl-8 Protein EGL-8 0.065
gpb-1 Protein GPB-1 0.063
stim-1 Protein STIM-1 0.051
T14B1.1 Protein T14B1.1 0.050
stn-1 Protein STN-1 0.049
unc-105 Protein UNC-105 0.048
nrx-1 Protein NRX-1 0.045
grk-2 Protein GRK-2 0.045
egl-30 Protein EGL-30 0.044
unc-10 Protein UNC-10 0.042
CELE_Y53F4B.5 Protein Y53F4B.5 0.039
rgs-6 Protein RGS-6 0.039
F54G2.1 Protein F54G2.1 0.035
pmt-1 Protein PMT-1 0.032
unc-38 Protein UNC-38 0.031
unc-31 Protein UNC-31 0.030
egl-5 Protein EGL-5 0.030
sgca-1 Protein SGCA-1 0.028
F45E4.3 Protein F45E4.3 0.028
dys-1 Protein DYS-1 0.027
R07E3.1 Protein R07E3.1 0.025
cpna-1 Protein CPNA-1 0.025
let-23 Protein LET-23 0.024
sel-2 Protein SEL-2 0.024
pkg-1 Protein PKG-1 0.023
F28E10.1 Protein F28E10.1 0.023
ceh-22 Protein CEH-22 0.022
eat-4 Protein EAT-4 0.022
trp-1 Protein TRP-1 0.021
tax-6 Protein TAX-6 0.021
sol-1 Protein SOL-1 0.020
tag-172 Protein TAG-172 0.020
nhr-153 Protein NHR-153 0.020
camt-1 Protein CAMT-1 0.019
csnk-1 Protein CSNK-1 0.019
unc-13 Protein UNC-13 0.018
zfp-1 Protein ZFP-1 0.018
twk-18 Protein TWK-18 0.018
shk-1 Protein SHK-1 0.018
ccb-1 Protein CCB-1 0.016
CELE_D1025.1 Protein D1025.1 0.016
ZC190.4 Protein ZC190.4 0.016
mig-17 Protein MIG-17 0.016
glr-5 Protein GLR-5 0.016
ilys-4 Protein ILYS-4 0.016
R03G8.3 Protein R03G8.3 0.015
efl-2 Protein EFL-2 0.015
spp-14 Protein SPP-14 0.015
CELE_Y44A6D.3 Protein Y44A6D.3 0.015
ceh-48 Protein CEH-48 0.015
CELE_T04H1.2 Protein T04H1.2 0.015
T07H6.4 Protein T07H6.4 0.014
acs-16 Protein ACS-16 0.014
CELE_R13H7.2 Protein R13H7.2 0.014
lim-9 Protein LIM-9 0.014
eat-16 Protein EAT-16 0.014
egl-36 Protein EGL-36 0.014
unc-77 Protein UNC-77 0.013
F46C5.6 Protein F46C5.6 0.013
unc-11 Protein UNC-11 0.013
odr-1 Protein ODR-1 0.013
lgc-46 Protein LGC-46 0.013
VM106R.1 Protein VM106R.1 0.013
F54E4.3 Protein F54E4.3 0.013
amx-3 Protein AMX-3 0.012
twk-35 Protein TWK-35 0.012
nlg-1 Protein NLG-1 0.012
T25G3.4 Protein T25G3.4 0.012
xbx-3 Protein XBX-3 0.012
cca-1 Protein CCA-1 0.012
aex-2 Protein AEX-2 0.012
rgs-2 Protein RGS-2 0.012
gar-2 Protein GAR-2 0.012
frm-2 Protein FRM-2 0.011
let-607 Protein LET-607 0.011
K09E4.4 Protein K09E4.4 0.011
rgs-5 Protein RGS-5 0.011
grk-1 Protein GRK-1 0.011
nmur-4 Protein NMUR-4 0.011
syd-1 Protein SYD-1 0.011
F32D8.10 Protein F32D8.10 0.011
CELE_C30H7.2 Protein C30H7.2 0.011
CELE_C01B10.10 Protein C01B10.10 0.011
F10C2.3 Protein F10C2.3 0.011
F28F5.4 Protein F28F5.4 0.010
F26A3.4 Protein F26A3.4 0.010
sec-10 Protein SEC-10 0.010
gpa-16 Protein GPA-16 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ARHGAP1 Rho GTPase activating protein 1 0.933
TBCD tubulin folding cofactor D 0.548
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.534
FADS2 fatty acid desaturase 2 0.328
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.250
ARRB1 arrestin, beta 1 0.183
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.125
TUBB2B tubulin, beta 2B 0.124
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.102
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.098
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.093
DRD2 dopamine receptor D2 0.090
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.090
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.089
RHOA ras homolog gene family, member A 0.081
RHOC ras homolog gene family, member C 0.076
ARL3 ADP-ribosylation factor-like 3 0.050
SC4MOL sterol-C4-methyl oxidase-like 0.049
DMD dystrophin 0.040
MPRIP myosin phosphatase Rho interacting protein 0.037
DHCR7 7-dehydrocholesterol reductase 0.036
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.035
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.033
DIAPH1 diaphanous homolog 1 (Drosophila) 0.032
LPHN1 latrophilin 1 0.021
ARHGAP22 Rho GTPase activating protein 22 0.021
EZR ezrin 0.021
UNC119 unc-119 homolog (C. elegans) 0.021
GFI1B growth factor independent 1B transcription repressor 0.020
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.019
CYTH2 cytohesin 2 0.018
LTBP4 latent transforming growth factor beta binding protein 4 0.017
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.017
PPP1R12C protein phosphatase 1, regulatory (inhibitor) subunit 12C 0.016
RTKN rhotekin 0.015
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.015
NECAB2 N-terminal EF-hand calcium binding protein 2 0.014
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.014
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.013
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.013
UTRN utrophin 0.013
MEGF8 multiple EGF-like-domains 8 0.012
GPX4 glutathione peroxidase 4 (phospholipid hydroperoxidase) 0.012
IGF1R insulin-like growth factor 1 receptor 0.012
ARL2BP ADP-ribosylation factor-like 2 binding protein 0.011
RHOG ras homolog gene family, member G (rho G) 0.011
ING2 inhibitor of growth family, member 2 0.011
JUP junction plakoglobin 0.011
ADORA1 adenosine A1 receptor 0.011
RAB13 RAB13, member RAS oncogene family 0.010
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.010
DTNA dystrobrevin, alpha 0.010
BZRAP1 benzodiazapine receptor (peripheral) associated protein 1 0.010
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism