The network for 'ventricular cardiac muscle cell action potential' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ventricular cardiac muscle cell action potential

An action potential that occurs in a ventricular cardiac muscle cell.

Mus musculus
Name Description Probability Func Analog Organism
Scn5a sodium channel, voltage-gated, type V, alpha 1.000
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 1.000
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.999
Tbx5 T-box 5 0.998
Ryr2 ryanodine receptor 2, cardiac 0.996
Dmd dystrophin, muscular dystrophy 0.975
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.920
Tbx3 T-box 3 0.906
Dsg2 desmoglein 2 0.903
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.857
Hand2 heart and neural crest derivatives expressed transcript 2 0.832
Gja1 gap junction protein, alpha 1 0.784
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.783
Nos3 nitric oxide synthase 3, endothelial cell 0.779
Tjp1 tight junction protein 1 0.770
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.725
Ldb3 LIM domain binding 3 0.687
Kcnk3 potassium channel, subfamily K, member 3 0.686
Csda cold shock domain protein A 0.685
Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit 0.679
Gjb2 gap junction protein, beta 2 0.678
Gata4 GATA binding protein 4 0.634
Casq2 calsequestrin 2 0.628
Cxadr coxsackie virus and adenovirus receptor 0.625
Xirp1 xin actin-binding repeat containing 1 0.616
Itga7 integrin alpha 7 0.605
Klk6 kallikrein related-peptidase 6 0.587
Slc26a4 solute carrier family 26, member 4 0.580
Des desmin 0.575
Dsp desmoplakin 0.530
Pygm muscle glycogen phosphorylase 0.529
Zfpm2 zinc finger protein, multitype 2 0.515
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.497
Mmp15 matrix metallopeptidase 15 0.496
Dsc2 desmocollin 2 0.488
Dmpk dystrophia myotonica-protein kinase 0.481
Gjb5 gap junction protein, beta 5 0.476
Ppl periplakin 0.465
Gata6 GATA binding protein 6 0.449
Gjb6 gap junction protein, beta 6 0.433
Myom2 myomesin 2 0.422
Dtna dystrobrevin alpha 0.418
Scn1a sodium channel, voltage-gated, type I, alpha 0.417
Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) 0.396
Tcf15 transcription factor 15 0.389
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.354
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.320
Cckbr cholecystokinin B receptor 0.312
Gli1 GLI-Kruppel family member GLI1 0.305
Mybpc3 myosin binding protein C, cardiac 0.289
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.258
Dnajb5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.243
Cav3 caveolin 3 0.233
Slurp1 secreted Ly6/Plaur domain containing 1 0.233
Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta 0.228
Rtn2 reticulon 2 (Z-band associated protein) 0.222
Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 0.221
Mt4 metallothionein 4 0.219
Actn2 actinin alpha 2 0.214
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.210
Pdgfb platelet derived growth factor, B polypeptide 0.195
Hrc histidine rich calcium binding protein 0.194
Pcdh12 protocadherin 12 0.194
Nfic nuclear factor I/C 0.188
Ocln occludin 0.183
Jag1 jagged 1 0.182
Emp2 epithelial membrane protein 2 0.181
Tcfap2c transcription factor AP-2, gamma 0.175
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.172
Fgf12 fibroblast growth factor 12 0.171
Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 0.170
Cldn3 claudin 3 0.168
Kel Kell blood group 0.165
Epas1 endothelial PAS domain protein 1 0.161
Oprd1 opioid receptor, delta 1 0.160
Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 0.157
Ighmbp2 immunoglobulin mu binding protein 2 0.155
Tmem30b transmembrane protein 30B 0.151
Srrm4 serine/arginine repetitive matrix 4 0.151
Sardh sarcosine dehydrogenase 0.150
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.149
Fut2 fucosyltransferase 2 0.149
Sgcg sarcoglycan, gamma (dystrophin-associated glycoprotein) 0.149
Foxa1 forkhead box A1 0.147
Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A 0.147
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.146
Hopx HOP homeobox 0.145
Sox18 SRY-box containing gene 18 0.144
Srpk3 serine/arginine-rich protein specific kinase 3 0.144
Jup junction plakoglobin 0.144
Wfdc2 WAP four-disulfide core domain 2 0.141
Hr hairless 0.140
Ckmt2 creatine kinase, mitochondrial 2 0.138
Tnnt2 troponin T2, cardiac 0.137
Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.136
Rasip1 Ras interacting protein 1 0.136
Atp4a ATPase, H+/K+ exchanging, gastric, alpha polypeptide 0.134
Irx4 Iroquois related homeobox 4 (Drosophila) 0.131
Popdc3 popeye domain containing 3 0.126
Perp PERP, TP53 apoptosis effector 0.124
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
JUP junction plakoglobin 0.989
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.975
DSP desmoplakin 0.958
KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 0.888
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.870
PSEN1 presenilin 1 0.856
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.836
KCNE1 potassium voltage-gated channel, Isk-related family, member 1 0.751
CTNND1 catenin (cadherin-associated protein), delta 1 0.710
DSG2 desmoglein 2 0.626
MAPK12 mitogen-activated protein kinase 12 0.565
DSC2 desmocollin 2 0.534
KRT14 keratin 14 0.418
SNTG2 syntrophin, gamma 2 0.252
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.248
SCN5A sodium channel, voltage-gated, type V, alpha subunit 0.232
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.213
APC adenomatous polyposis coli 0.177
BTRC beta-transducin repeat containing 0.149
PKP2 plakophilin 2 0.138
DMD dystrophin 0.120
PTPRJ protein tyrosine phosphatase, receptor type, J 0.120
MARK3 MAP/microtubule affinity-regulating kinase 3 0.092
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.089
CTNNBIP1 catenin, beta interacting protein 1 0.064
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.061
KRT18 keratin 18 0.047
DTNA dystrobrevin, alpha 0.040
PKP3 plakophilin 3 0.038
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.036
FRMD5 FERM domain containing 5 0.035
SFN stratifin 0.035
DSC3 desmocollin 3 0.030
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.026
CLCN3 chloride channel 3 0.022
WDYHV1 WDYHV motif containing 1 0.021
KCNB1 potassium voltage-gated channel, Shab-related subfamily, member 1 0.019
ERBB2IP erbb2 interacting protein 0.018
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 0.016
AKAP6 A kinase (PRKA) anchor protein 6 0.015
SPTB spectrin, beta, erythrocytic 0.014
KRT8 keratin 8 0.013
KRT5 keratin 5 0.013
UTRN utrophin 0.013
RHAG Rh-associated glycoprotein 0.012
GLIS2 GLIS family zinc finger 2 0.012
HRH3 histamine receptor H3 0.012
DSC1 desmocollin 1 0.011
EHD1 EH-domain containing 1 0.011
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 0.010
EGFR epidermal growth factor receptor 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Cav1 caveolin 1, caveolae protein 1.000
LOC100362824 caveolin 2-like 0.999
Cav2 caveolin 2 0.998
Myh6 myosin, heavy chain 6, cardiac muscle, alpha 0.440
Dhrs7c dehydrogenase/reductase (SDR family) member 7C 0.290
App amyloid beta (A4) precursor protein 0.279
Pgam2 phosphoglycerate mutase 2 (muscle) 0.203
Gja1 gap junction protein, alpha 1 0.166
Casq2 calsequestrin 2 (cardiac muscle) 0.148
Ogn osteoglycin 0.103
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.097
Ldb3 LIM domain binding 3 0.097
Kcnq1 potassium voltage-gated channel, KQT-like subfamily, member 1 0.093
Adcy5 adenylate cyclase 5 0.084
Asph aspartate-beta-hydroxylase 0.083
Ttn titin 0.082
LOC685244 similar to IQ motif and Sec7 domain 2 0.081
Jak1 Janus kinase 1 0.079
Inha inhibin alpha 0.075
Myl3 myosin, light chain 3, alkali; ventricular, skeletal, slow 0.074
Hspb2 heat shock protein beta 2 0.058
Pbrm1 polybromo 1 0.057
Tcf12 transcription factor 12 0.055
Sdpr serum deprivation response 0.053
Cpd carboxypeptidase D 0.050
Wipf3 WAS/WASL interacting protein family, member 3 0.049
Rpl3l ribosomal protein L3-like 0.049
Inpp5j inositol polyphosphate-5-phosphatase J 0.048
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.045
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.041
Ehd2 EH-domain containing 2 0.037
Ptpn3 protein tyrosine phosphatase, non-receptor type 3 0.036
Sptbn1 spectrin, beta, non-erythrocytic 1 0.036
Plb1 phospholipase B1 0.036
Galnt1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) 0.035
Ckmt2 creatine kinase, mitochondrial 2, sarcomeric 0.033
Lrrc4b leucine rich repeat containing 4B 0.033
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.032
Nrap nebulin-related anchoring protein 0.032
Rnf207 ring finger protein 207 0.032
Maoa monoamine oxidase A 0.032
Fhl1 four and a half LIM domains 1 0.031
Trim72 tripartite motif-containing 72 0.031
Slc25a29 solute carrier family 25, member 29 0.030
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.030
Kif1c kinesin family member 1C 0.029
Phyhip phytanoyl-CoA 2-hydroxylase interacting protein 0.029
Apobec2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 0.028
Efemp1 EGF-containing fibulin-like extracellular matrix protein 1 0.028
Dsg2 desmoglein 2 0.028
Asb2 ankyrin repeat and SOCS box-containing 2 0.027
Sept2 septin 2 0.027
Rimbp2 RIMS binding protein 2 0.027
LOC683460 hypothetical protein LOC683460 0.027
Ankrd9 ankyrin repeat domain 9 0.026
Amotl2 angiomotin like 2 0.025
Mak male germ cell-associated kinase 0.025
Ckm creatine kinase, muscle 0.025
Strn striatin, calmodulin binding protein 0.024
Phka1 phosphorylase kinase, alpha 1 0.023
Gnb3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.023
RGD1310269 hypothetical LOC314472 0.023
Cox8b cytochrome c oxidase, subunit VIIIb 0.023
Begain brain-enriched guanylate kinase-associated 0.023
Krt8 keratin 8 0.023
Sp1 Sp1 transcription factor 0.023
Cnksr2 connector enhancer of kinase suppressor of Ras 2 0.022
Hhatl hedgehog acyltransferase-like 0.022
Csrp3 cysteine and glycine-rich protein 3 0.022
Fry furry homolog (Drosophila) 0.022
Ppard peroxisome proliferator-activated receptor delta 0.021
Ddah1 dimethylarginine dimethylaminohydrolase 1 0.021
Hand2 heart and neural crest derivatives expressed 2 0.021
Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.021
Kcnk3 potassium channel, subfamily K, member 3 0.020
Nrp1 neuropilin 1 0.020
Dsp desmoplakin 0.020
Prdm2 PR domain containing 2, with ZNF domain 0.020
Opcml opioid binding protein/cell adhesion molecule-like 0.019
Gja3 gap junction protein, alpha 3 0.019
Smpx small muscle protein, X-linked 0.019
Vegfa vascular endothelial growth factor A 0.019
Lats2 large tumor suppressor 2 0.019
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.019
RT1-DOa RT1 class II, locus DOa 0.018
Pkp2 plakophilin 2 0.018
Mtus1 mitochondrial tumor suppressor 1 0.018
Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 0.018
Skil SKI-like oncogene 0.018
Neurl2 neuralized homolog 2 (Drosophila) 0.018
Sft2d2 SFT2 domain containing 2 0.018
Lmod2 leiomodin 2 (cardiac) 0.018
Tpt1 tumor protein, translationally-controlled 1 0.017
Arhgap21 Rho GTPase activating protein 21 0.017
Lphn1 latrophilin 1 0.017
Nfic nuclear factor I/C 0.017
Bsn bassoon 0.017
Myom1 myomesin 1 0.017
St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.017
Baiap2l1 BAI1-associated protein 2-like 1 0.017
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism