IMP
Process View
The network for 'vitamin d biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
vitamin d biosynthetic process
The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Cyp2c38 | cytochrome P450, family 2, subfamily c, polypeptide 38 | 0.983 | |
| Cyp2c29 | cytochrome P450, family 2, subfamily c, polypeptide 29 | 0.981 | |
| Cyp3a11 | cytochrome P450, family 3, subfamily a, polypeptide 11 | 0.979 | |
| Cps1 | carbamoyl-phosphate synthetase 1 | 0.972 | |
| Otc | ornithine transcarbamylase | 0.956 | |
| Nr1i2 | nuclear receptor subfamily 1, group I, member 2 | 0.920 | |
| Pck1 | phosphoenolpyruvate carboxykinase 1, cytosolic | 0.898 | |
| Cyp3a25 | cytochrome P450, family 3, subfamily a, polypeptide 25 | 0.881 | |
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.868 | |
| Sult1d1 | sulfotransferase family 1D, member 1 | 0.854 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.841 | |
| Cyp2b10 | cytochrome P450, family 2, subfamily b, polypeptide 10 | 0.840 | |
| Hpd | 4-hydroxyphenylpyruvic acid dioxygenase | 0.838 | |
| Cyp2a12 | cytochrome P450, family 2, subfamily a, polypeptide 12 | 0.827 | |
| Cyp2c50 | cytochrome P450, family 2, subfamily c, polypeptide 50 | 0.826 | |
| Cyp4a14 | cytochrome P450, family 4, subfamily a, polypeptide 14 | 0.812 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.811 | |
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.809 | |
| G6pc | glucose-6-phosphatase, catalytic | 0.717 | |
| Nr5a2 | nuclear receptor subfamily 5, group A, member 2 | 0.703 | |
| Ugt2b1 | UDP glucuronosyltransferase 2 family, polypeptide B1 | 0.701 | |
| Cyp2b9 | cytochrome P450, family 2, subfamily b, polypeptide 9 | 0.669 | |
| Cyp7a1 | cytochrome P450, family 7, subfamily a, polypeptide 1 | 0.651 | |
| Rdh7 | retinol dehydrogenase 7 | 0.622 | |
| Crp | C-reactive protein, pentraxin-related | 0.593 | |
| Cyp2c54 | cytochrome P450, family 2, subfamily c, polypeptide 54 | 0.585 | |
| Sult1b1 | sulfotransferase family 1B, member 1 | 0.567 | |
| Lep | leptin | 0.558 | |
| Abcc2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.521 | |
| Nr1i3 | nuclear receptor subfamily 1, group I, member 3 | 0.512 | |
| Ugt2b34 | UDP glucuronosyltransferase 2 family, polypeptide B34 | 0.477 | |
| Insr | insulin receptor | 0.472 | |
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.467 | |
| Cyp3a13 | cytochrome P450, family 3, subfamily a, polypeptide 13 | 0.454 | |
| Hrg | histidine-rich glycoprotein | 0.437 | |
| Azgp1 | alpha-2-glycoprotein 1, zinc | 0.437 | |
| Ces2a | carboxylesterase 2A | 0.417 | |
| Cyp2d10 | cytochrome P450, family 2, subfamily d, polypeptide 10 | 0.407 | |
| Slc2a2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 0.397 | |
| Lepr | leptin receptor | 0.396 | |
| Cyp8b1 | cytochrome P450, family 8, subfamily b, polypeptide 1 | 0.389 | |
| Baat | bile acid-Coenzyme A: amino acid N-acyltransferase | 0.386 | |
| Il1a | interleukin 1 alpha | 0.382 | |
| Timd2 | T-cell immunoglobulin and mucin domain containing 2 | 0.368 | |
| Hsd3b2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 | 0.360 | |
| Hsd3b3 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 | 0.358 | |
| Tdo2 | tryptophan 2,3-dioxygenase | 0.354 | |
| Pigr | polymeric immunoglobulin receptor | 0.353 | |
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.341 | |
| Cyp1a2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | 0.341 | |
| Upp2 | uridine phosphorylase 2 | 0.341 | |
| Slc22a1 | solute carrier family 22 (organic cation transporter), member 1 | 0.337 | |
| Aldob | aldolase B, fructose-bisphosphate | 0.335 | |
| Bche | butyrylcholinesterase | 0.332 | |
| Hgd | homogentisate 1, 2-dioxygenase | 0.331 | |
| Aadac | arylacetamide deacetylase (esterase) | 0.318 | |
| Ces1g | carboxylesterase 1G | 0.317 | |
| Ugt2a3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.295 | |
| Vdr | vitamin D receptor | 0.295 | |
| Cyp4b1 | cytochrome P450, family 4, subfamily b, polypeptide 1 | 0.286 | |
| Cyp2d26 | cytochrome P450, family 2, subfamily d, polypeptide 26 | 0.284 | |
| Akr1d1 | aldo-keto reductase family 1, member D1 | 0.281 | |
| F13b | coagulation factor XIII, beta subunit | 0.280 | |
| Gsta2 | glutathione S-transferase, alpha 2 (Yc2) | 0.270 | |
| Mbl2 | mannose-binding lectin (protein C) 2 | 0.267 | |
| F9 | coagulation factor IX | 0.267 | |
| Cfhr1 | complement factor H-related 1 | 0.264 | |
| Apoh | apolipoprotein H | 0.263 | |
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.262 | |
| Serpina6 | serine (or cysteine) peptidase inhibitor, clade A, member 6 | 0.262 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.261 | |
| Slco1b2 | solute carrier organic anion transporter family, member 1b2 | 0.260 | |
| Cyp4a31 | cytochrome P450, family 4, subfamily a, polypeptide 31 | 0.258 | |
| Akr1c6 | aldo-keto reductase family 1, member C6 | 0.258 | |
| Mup5 | major urinary protein 5 | 0.257 | |
| Cyp2c39 | cytochrome P450, family 2, subfamily c, polypeptide 39 | 0.238 | |
| Adh7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 0.228 | |
| Cyp2c68 | cytochrome P450, family 2, subfamily c, polypeptide 68 | 0.221 | |
| Cml2 | camello-like 2 | 0.216 | |
| Ces1c | carboxylesterase 1C | 0.214 | |
| Apoc3 | apolipoprotein C-III | 0.213 | |
| Gata6 | GATA binding protein 6 | 0.213 | |
| Fabp1 | fatty acid binding protein 1, liver | 0.207 | |
| Cyp2d9 | cytochrome P450, family 2, subfamily d, polypeptide 9 | 0.203 | |
| Prlr | prolactin receptor | 0.199 | |
| Rdh16 | retinol dehydrogenase 16 | 0.193 | |
| F12 | coagulation factor XII (Hageman factor) | 0.193 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.187 | |
| Sult2a2 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 | 0.185 | |
| Plin1 | perilipin 1 | 0.184 | |
| Cyp2c69 | cytochrome P450, family 2, subfamily c, polypeptide 69 | 0.183 | |
| Gc | group specific component | 0.180 | |
| Cav1 | caveolin 1, caveolae protein | 0.177 | |
| Serpina1c | serine (or cysteine) peptidase inhibitor, clade A, member 1C | 0.174 | |
| Slc10a1 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1 | 0.172 | |
| Uox | urate oxidase | 0.171 | |
| Keg1 | kidney expressed gene 1 | 0.170 | |
| Acot12 | acyl-CoA thioesterase 12 | 0.167 | |
| Pik3c2g | phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide | 0.166 | |
| Mocs1 | molybdenum cofactor synthesis 1 | 0.166 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.987 | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.924 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.866 | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.846 | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.627 | |
| BCL3 | B-cell CLL/lymphoma 3 | 0.475 | |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.321 | |
| IL1R1 | interleukin 1 receptor, type I | 0.235 | |
| RXRA | retinoid X receptor, alpha | 0.092 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.083 | |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.072 | |
| JUB | jub, ajuba homolog (Xenopus laevis) | 0.054 | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.029 | |
| HR | hairless homolog (mouse) | 0.025 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.025 | |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.020 | |
| IL1R2 | interleukin 1 receptor, type II | 0.018 | |
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.018 | |
| IL1RN | interleukin 1 receptor antagonist | 0.017 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.015 | |
| EGR1 | early growth response 1 | 0.014 | |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.011 | |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 | 0.011 | |
| NOTCH1 | notch 1 | 0.011 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Cyp3a18 | cytochrome P450, family 3, subfamily a, polypeptide 18 | 0.493 | |
| Ugt2b | UDP glycosyltransferase 2 family, polypeptide B | 0.285 | |
| Il6 | interleukin 6 | 0.107 | |
| LOC293989 | cytochrome P450-like | 0.097 | |
| Cyp2a2 | cytochrome P450, family 2, subfamily a, polypeptide 2 | 0.087 | |
| Cyp3a23/3a1 | cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 | 0.068 | |
| Abcb11 | ATP-binding cassette, subfamily B (MDR/TAP), member 11 | 0.063 | |
| Il1a | interleukin 1 alpha | 0.063 | |
| Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.061 | |
| Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | 0.056 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.054 | |
| Cyp4f1 | cytochrome P450, family 4, subfamily f, polypeptide 1 | 0.043 | |
| Sult1b1 | sulfotransferase family, cytosolic, 1B, member 1 | 0.041 | |
| LOC494499 | LOC494499 protein | 0.039 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.036 | |
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.035 | |
| Cyp2b1 | cytochrome P450, family 2, subfamily b, polypeptide 1 | 0.035 | |
| Sult1c3 | sulfotransferase family, cytosolic, 1C, member 3 | 0.035 | |
| Selp | selectin P | 0.032 | |
| Ugt2b5 | UDP glucuronosyltransferase 2 family, polypeptide B5 | 0.031 | |
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.031 | |
| Sult2a1 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 0.030 | |
| Slc9a3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.027 | |
| Sult1c2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.027 | |
| Gjb3 | gap junction protein, beta 3 | 0.027 | |
| Ccl20 | chemokine (C-C motif) ligand 20 | 0.025 | |
| Cyp2a1 | cytochrome P450, family 2, subfamily a, polypeptide 1 | 0.025 | |
| Gabre | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.024 | |
| Cyp4a10 | cytochrome P450, family 4, subfamily a, polypeptide 10 | 0.021 | |
| Sult1e1 | sulfotransferase family 1E, estrogen-preferring, member 1 | 0.020 | |
| Cyp2d3 | cytochrome P450, family 2, subfamily d, polypeptide 3 | 0.020 | |
| Cyp2c22 | cytochrome P450, family 2, subfamily c, polypeptide 22 | 0.019 | |
| Apob | apolipoprotein B | 0.018 | |
| Fut1 | fucosyltransferase 1 | 0.018 | |
| Gja5 | gap junction protein, alpha 5 | 0.017 | |
| LOC100360403 | ATP-binding cassette, sub-family C, member 9-like | 0.017 | |
| Hipk3 | homeodomain interacting protein kinase 3 | 0.017 | |
| Prss3 | protease, serine, 3 | 0.016 | |
| Hoxb8 | homeo box B8 | 0.015 | |
| Omd | osteomodulin | 0.015 | |
| Galnt5 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) | 0.015 | |
| Cyp2d2 | cytochrome P450, family 2, subfamily d, polypeptide 2 | 0.015 | |
| Accn5 | amiloride-sensitive cation channel 5, intestinal | 0.014 | |
| Il2rb | interleukin 2 receptor, beta | 0.014 | |
| Birc3 | baculoviral IAP repeat-containing 3 | 0.014 | |
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.014 | |
| Insl3 | insulin-like 3 | 0.014 | |
| Cst8 | cystatin 8 (cystatin-related epididymal specific) | 0.014 | |
| Mc5r | melanocortin 5 receptor | 0.014 | |
| Brd1 | bromodomain containing 1 | 0.013 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.013 | |
| Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.013 | |
| Kl | Klotho | 0.013 | |
| Spink1 | serine peptidase inhibitor, Kazal type 1 | 0.013 | |
| Nr5a2 | nuclear receptor subfamily 5, group A, member 2 | 0.013 | |
| Irf1 | interferon regulatory factor 1 | 0.013 | |
| Adhfe1 | alcohol dehydrogenase, iron containing, 1 | 0.013 | |
| Clcn5 | chloride channel 5 | 0.013 | |
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.012 | |
| Obp3 | alpha-2u globulin PGCL4 | 0.012 | |
| Hsd3b5 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 | 0.012 | |
| Fut9 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) | 0.012 | |
| LOC290595 | hypothetical gene supported by AF152002 | 0.012 | |
| Dmgdh | dimethylglycine dehydrogenase | 0.012 | |
| Cyp3a9 | cytochrome P450, family 3, subfamily a, polypeptide 9 | 0.012 | |
| Tnf | tumor necrosis factor (TNF superfamily, member 2) | 0.012 | |
| Cyp2c13 | cytochrome P450, family 2, subfamily c, polypeptide 13 | 0.012 | |
| Cyp3a2 | cytochrome P450, family 3, subfamily a, polypeptide 2 | 0.012 | |
| Reg3g | regenerating islet-derived 3 gamma | 0.012 | |
| As3mt | arsenic (+3 oxidation state) methyltransferase | 0.012 | |
| Dpyd | dihydropyrimidine dehydrogenase | 0.011 | |
| Cyp2d4 | cytochrome P450, family 2, subfamily d, polypeptide 4 | 0.011 | |
| Fabp9 | fatty acid binding protein 9, testis | 0.011 | |
| Ceacam10 | carcinoembryonic antigen-related cell adhesion molecule 10 | 0.011 | |
| Ugt2b37 | UDP-glucuronosyltransferase 2 family, member 37 | 0.011 | |
| Pbsn | probasin | 0.011 | |
| Pfkfb1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 0.011 | |
| Alox5 | arachidonate 5-lipoxygenase | 0.011 | |
| Exosc6 | exosome component 6 | 0.011 | |
| Svs3a | seminal vesicle secretory protein 3A | 0.011 | |
| Cybrd1 | cytochrome b reductase 1 | 0.011 | |
| Mcpt8 | mast cell protease 8 | 0.011 | |
| Sval1 | seminal vesicle antigen-like 1 | 0.011 | |
| Sult5a1 | sulfotransferase family 5A, member 1 | 0.011 | |
| Clca4 | chloride channel accessory 4 | 0.010 | |
| Abcc2 | ATP-binding cassette, subfamily C (CFTR/MRP), member 2 | 0.010 | |
| Ms4a8a | membrane-spanning 4-domains, subfamily A, member 8A | 0.010 | |
| Dnase1 | deoxyribonuclease I | 0.010 | |
| Ces1f | carboxylesterase 1F | 0.010 | |
| Fat2 | FAT tumor suppressor homolog 2 (Drosophila) | 0.010 | |
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.010 | |
| Prl8a4 | prolactin family 8, subfamily a, member 4 | 0.010 | |
| Il1rap | interleukin 1 receptor accessory protein | 0.010 |