The network for 'canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.

Danio rerio
Name Description Probability Func Analog Organism
gata6 GATA-binding protein 6 0.783
met met proto-oncogene (hepatocyte growth factor receptor) 0.458
hlxb9la homeo box HB9 like a 0.297
nkx6.1 NK6 transcription factor related, locus 1 (Drosophila) 0.235
frem3 Fras1 related extracellular matrix 3 0.184
irx3a iroquois homeobox protein 3a 0.178
mnx1 motor neuron and pancreas homeobox 1 0.124
olig4 oligodendrocyte transcription factor 4 0.119
rarab retinoic acid receptor, alpha b 0.115
foxa1 forkhead box A1 0.089
meis3 myeloid ecotropic viral integration site 3 0.087
il17rd interleukin 17 receptor D 0.086
irx4a iroquois homeobox protein 4a 0.082
nkx2.2a NK2 transcription factor related 2a 0.081
ntla no tail a 0.077
foxa2 forkhead box A2 0.076
nkx6.2 NK6 transcription factor related, locus 2 0.075
foxa3 forkhead box A3 0.074
cdx1b caudal type homeobox 1 b 0.072
sox3 SRY-box containing gene 3 0.070
oep one-eyed pinhead 0.063
lmo4a LIM domain only 4a 0.060
flh floating head 0.058
znf503 zinc finger protein 503 0.055
ctgf connective tissue growth factor 0.052
pou5f1 POU domain, class 5, transcription factor 1 0.052
wnt11 wingless-type MMTV integration site family, member 11 0.052
pcdh18b protocadherin 18b 0.051
lef1 lymphocyte enhancer binding factor 1 0.049
irf6 interferon regulatory factor 6 0.048
rnasel1 ribonuclease like 1 0.047
dld deltaD 0.047
cdx4 caudal type homeo box transcription factor 4 0.046
hlxb9lb homeo box HB9 like b 0.046
ins preproinsulin 0.045
hoxc8a homeo box C8a 0.044
lhx5 LIM homeobox 5 0.042
olig2 oligodendrocyte lineage transcription factor 2 0.042
shha sonic hedgehog a 0.039
smad9 MAD homolog 9 (Drosophila) 0.039
irx7 iroquois homeobox protein 7 0.038
hoxb1a homeo box B1a 0.037
eng2b engrailed 2b 0.036
hoxa4a homeo box A4a 0.036
hgfa hepatocyte growth factor a 0.036
gli2a GLI-Kruppel family member GLI2a 0.036
hoxb2a homeo box B2a 0.034
wnt3a wingless-type MMTV integration site family, member 3A 0.033
bon bonnie and clyde 0.032
scube2 signal peptide, CUB domain, EGF-like 2 0.031
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.030
gdf6a growth differentiation factor 6a 0.030
tal2 T-cell acute lymphocytic leukemia 2 0.030
foxb1.2 forkhead box B1.2 0.029
lft1 lefty1 0.029
sst2 somatostatin 2 0.028
pcdh18a protocadherin 18a 0.028
dab1a disabled homolog 1a (Drosophila) 0.028
six3a sine oculis homeobox homolog 3a 0.027
pax4 paired box 4 0.027
chd7 chromodomain helicase DNA binding protein 7 0.026
dscam Down syndrome cell adhesion molecule 0.026
lfng lunatic fringe homolog 0.024
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.024
irx1b iroquois homeobox protein 1, b 0.024
mpped2 metallophosphoesterase domain containing 2 0.024
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.023
epha4a eph receptor A4a 0.023
prdm14 PR domain containing 14 0.022
hoxa2b homeo box A2b 0.021
hoxd12a homeo box D12a 0.021
tbx2a T-box gene 2a 0.021
lhx1a LIM homeobox 1a 0.020
hoxd11a homeo box D11a 0.020
zgc:64114 zgc:64114 0.020
fbn2b fibrillin 2b 0.018
dact2 dapper homolog 2, antagonist of beta-catenin (xenopus) 0.018
tpbgl trophoblast glycoprotein-like 0.018
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.018
eng2a engrailed 2a 0.018
esrra estrogen-related receptor alpha 0.017
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.017
prtga protogenin homolog a (Gallus gallus) 0.017
dzip1 DAZ interacting protein 1 0.017
gsc goosecoid 0.017
notch1a notch homolog 1a 0.017
otpb orthopedia homolog b 0.017
hfe2 hemochromatosis type 2 0.017
pbx4 pre-B-cell leukemia transcription factor 4 0.017
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.017
wnt8a wingless-type MMTV integration site family, member 8a 0.016
msxc muscle segment homeobox C 0.016
cdc25 cell division cycle 25 homolog 0.016
gcga glucagon a and glucagon a-like 0.016
rfng radical fringe homolog (Drosophila) 0.016
gata2a GATA-binding protein 2a 0.016
msxb muscle segment homeobox B 0.015
sst1.1 somatostatin 1, tandem duplicate 1 0.015
hoxa10b homeo box A10b 0.015
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.015
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Pitx2 paired-like homeodomain transcription factor 2 0.979
Tbx3 T-box 3 0.979
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.941
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.806
Tbx5 T-box 5 0.799
Pitx1 paired-like homeodomain transcription factor 1 0.767
Scn5a sodium channel, voltage-gated, type V, alpha 0.759
Tcfap2a transcription factor AP-2, alpha 0.607
Chd7 chromodomain helicase DNA binding protein 7 0.592
Hoxa1 homeobox A1 0.579
Sall4 sal-like 4 (Drosophila) 0.385
Shh sonic hedgehog 0.349
Foxg1 forkhead box G1 0.343
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.333
Tbx4 T-box 4 0.317
Fgfr2 fibroblast growth factor receptor 2 0.315
Gja5 gap junction protein, alpha 5 0.295
Pax2 paired box gene 2 0.283
Lrp5 low density lipoprotein receptor-related protein 5 0.232
Hand2 heart and neural crest derivatives expressed transcript 2 0.197
Lrp6 low density lipoprotein receptor-related protein 6 0.178
Otx2 orthodenticle homolog 2 (Drosophila) 0.178
Smad6 MAD homolog 6 (Drosophila) 0.178
Fgf10 fibroblast growth factor 10 0.168
Ighmbp2 immunoglobulin mu binding protein 2 0.164
Vangl2 vang-like 2 (van gogh, Drosophila) 0.160
Eya1 eyes absent 1 homolog (Drosophila) 0.148
Foxc2 forkhead box C2 0.142
Lef1 lymphoid enhancer binding factor 1 0.117
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.104
Lmx1a LIM homeobox transcription factor 1 alpha 0.095
Hand1 heart and neural crest derivatives expressed transcript 1 0.093
Pax3 paired box gene 3 0.089
Foxc1 forkhead box C1 0.089
Bdnf brain derived neurotrophic factor 0.089
Fgf8 fibroblast growth factor 8 0.089
Gsc goosecoid homeobox 0.086
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.072
Gbx2 gastrulation brain homeobox 2 0.071
Zic3 zinc finger protein of the cerebellum 3 0.070
Irx3 Iroquois related homeobox 3 (Drosophila) 0.070
Jag1 jagged 1 0.068
Gata4 GATA binding protein 4 0.058
Noto notochord homolog (Xenopus laevis) 0.057
Dll4 delta-like 4 (Drosophila) 0.057
Wnt3a wingless-related MMTV integration site 3A 0.056
Prrx1 paired related homeobox 1 0.055
Wt1 Wilms tumor 1 homolog 0.054
Gsk3b glycogen synthase kinase 3 beta 0.046
Hoxa3 homeobox A3 0.046
Msx1 homeobox, msh-like 1 0.045
Myf5 myogenic factor 5 0.041
T brachyury 0.040
Efnb2 ephrin B2 0.039
Alx1 ALX homeobox 1 0.038
Hoxa13 homeobox A13 0.035
Nodal nodal 0.034
Zeb1 zinc finger E-box binding homeobox 1 0.034
Bmp5 bone morphogenetic protein 5 0.033
Tcf21 transcription factor 21 0.032
Hoxa2 homeobox A2 0.032
Htt huntingtin 0.031
Rnf2 ring finger protein 2 0.031
Rnf111 ring finger 111 0.030
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.030
Bmp4 bone morphogenetic protein 4 0.030
Wdr5 WD repeat domain 5 0.030
Gata3 GATA binding protein 3 0.030
Gata6 GATA binding protein 6 0.029
Rarb retinoic acid receptor, beta 0.028
Tbx1 T-box 1 0.028
Rarg retinoic acid receptor, gamma 0.028
Smad7 MAD homolog 7 (Drosophila) 0.026
Otx1 orthodenticle homolog 1 (Drosophila) 0.026
Cxadr coxsackie virus and adenovirus receptor 0.025
Prdm6 PR domain containing 6 0.024
Foxh1 forkhead box H1 0.024
Rxra retinoid X receptor alpha 0.024
Mecom MDS1 and EVI1 complex locus 0.024
Runx2 runt related transcription factor 2 0.024
Dlx2 distal-less homeobox 2 0.024
Hmx3 H6 homeobox 3 0.024
Pax9 paired box gene 9 0.023
Tbx20 T-box 20 0.023
Hoxd1 homeobox D1 0.022
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.022
Sox2 SRY-box containing gene 2 0.022
Col13a1 collagen, type XIII, alpha 1 0.020
Sox9 SRY-box containing gene 9 0.020
Axin2 axin2 0.020
Osr1 odd-skipped related 1 (Drosophila) 0.020
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.020
Hoxb3 homeobox B3 0.019
Gata5 GATA binding protein 5 0.019
Wnt5a wingless-related MMTV integration site 5A 0.019
Hoxd3 homeobox D3 0.019
Chrd chordin 0.019
Lhx9 LIM homeobox protein 9 0.019
Lpar3 lysophosphatidic acid receptor 3 0.019
Ryr2 ryanodine receptor 2, cardiac 0.019
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism