The network for 'reflex' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

reflex

An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness.

Danio rerio
Name Description Probability Func Analog Organism
pcdh15a protocadherin 15a 0.649
pax5 paired box gene 5 0.594
ift88 intraflagellar transport 88 homolog 0.518
gng8 guanine nucleotide binding protein (G protein), gamma 8 0.510
cacna1da calcium channel, voltage-dependent, L type, alpha 1D subunit, a 0.499
cdh23 cadherin-like 23 0.498
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.478
slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.470
pax8 paired box gene 8 0.451
vcanb versican b 0.449
atoh1a atonal homolog 1a 0.443
gngt2b guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b 0.425
gfi1.2 growth factor independent 1.2 0.422
pax2a paired box gene 2a 0.330
synj1 synaptojanin 1 0.277
gfi1.1 growth factor independent 1.1 0.240
dlx6a distal-less homeobox gene 6a 0.228
ush1c Usher syndrome 1C (autosomal recessive, severe) 0.220
myo7aa myosin VIIAa 0.207
tsen54 tRNA splicing endonuclease 54 homolog (S. cerevisiae) 0.205
rc3 rabconnectin 3 0.166
apex2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 0.150
cyfip2 cytoplasmic FMR1 interacting protein 2 0.146
nsfa N-ethylmaleimide-sensitive factor a 0.138
robo4 roundabout homolog 4 0.136
phox2a paired-like homeobox 2a 0.128
grhl2b grainyhead-like 2b (Drosophila) 0.126
neurod2 neurogenic differentiation 2 0.124
scn8aa sodium channel, voltage-gated, type VIII, alpha a 0.120
tmie transmembrane inner ear 0.120
appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.114
cobl cordon-bleu homolog (mouse) 0.112
zmynd11 zinc finger, MYND domain containing 11 0.110
camkvb CaM kinase-like vesicle-associated b 0.109
gng5 guanine nucleotide binding protein (G protein), gamma 5 0.108
vsx2 visual system homeobox 2 0.105
gng2 guanine nucleotide binding protein (G protein), gamma 2 0.104
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.094
cnr1 cannabinoid receptor 1 0.093
ndr2 nodal-related 2 0.092
gng12a guanine nucleotide binding protein (G protein), gamma 12a 0.089
robo2 roundabout homolog 2 0.086
six3b sine oculis homeobox homolog 3b 0.086
pdzd7a PDZ domain containing 7a 0.084
gngt2a guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a 0.082
sncgb synuclein, gamma b (breast cancer-specific protein 1) 0.081
kal1a Kallmann syndrome 1a sequence 0.079
atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 0.077
k23 k23 gene 0.074
wnt1 wingless-type MMTV integration site family, member 1 0.074
kctd12.1 potassium channel tetramerisation domain containing 12.1 0.073
egr1 early growth response 1 0.071
lhx6 LIM homeobox 6 0.071
tshb thyroid stimulating hormone, beta subunit 0.070
pou4f1 POU domain, class 4, transcription factor 1 0.069
cldnk claudin k 0.069
atp1a3b ATPase, Na+/K+ transporting, alpha 3b polypeptide 0.068
pax2b paired box gene 2b 0.067
bdnf brain-derived neurotrophic factor 0.067
irx4b iroquois homeobox protein 4b 0.063
zbtb4 zinc finger and BTB domain containing 4 0.063
LOC565106 novel protein similar to vertebrate calpain 1 (CAPN1) 0.063
gpia glucose phosphate isomerase a 0.061
capn2a calpain 2, (m/II) large subunit a 0.061
th tyrosine hydroxylase 0.060
rgs4 regulator of G-protein signalling 4 0.058
crygm4 crystallin, gamma M4 0.058
elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.058
isl1 islet1 0.057
pou1f1 POU domain, class 1, transcription factor 1 0.056
slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 0.056
drd2a dopamine receptor D2a 0.056
cntn1b contactin 1b 0.056
drd2b dopamine receptor D2b 0.055
ptprb protein tyrosine phosphatase, receptor type, b 0.055
gng13a guanine nucleotide binding protein (G protein), gamma 13a 0.054
rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.054
si:dkey-202c5.1 si:dkey-202c5.1 0.053
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.052
nf1a neurofibromin 1a 0.051
gng7 guanine nucleotide binding protein (G protein), gamma 7 0.050
sec61b Sec61 beta subunit 0.050
kal1b Kallmann syndrome 1b sequence 0.050
vsx1 visual system homeobox 1 homolog, chx10-like 0.049
nkx2.1a NK2 homeobox 1a 0.049
atoh7 atonal homolog 7 0.049
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.048
oc90 otoconin 90 0.048
nkx2.3 NK2 transcription factor related 3 0.047
nkx3.2 NK3 homeobox 2 0.047
capns1a calpain, small subunit 1 a 0.046
ptf1a pancreas specific transcription factor, 1a 0.046
gpr98 G protein-coupled receptor 98 0.045
esr2a estrogen receptor 2a 0.044
her11 hairy-related 11 0.044
pax6a paired box gene 6a 0.043
pou3f3a POU class 3 homeobox 3a 0.043
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.043
grnb granulin b 0.043
nkx2.2a NK2 transcription factor related 2a 0.042
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Poxn Pox neuro 0.165
Gr64e Gustatory receptor 64e 0.104
gfA giant fibre A 0.055
Gr64a Gustatory receptor 64a 0.039
ppk28 pickpocket 28 0.038
Gr63a Gustatory receptor 63a 0.035
acj6 abnormal chemosensory jump 6 0.034
Gr64f Gustatory receptor 64f 0.032
eag ether a go-go 0.031
Gr43a Gustatory receptor 43a 0.031
ro rough 0.030
HLHmgamma E(spl) region transcript mgamma 0.028
Tre Trehalose-sensitivity 0.023
Gr61a Gustatory receptor 61a 0.017
para paralytic 0.017
Gr59c Gustatory receptor 59c 0.016
stan starry night 0.015
Gr64c Gustatory receptor 64c 0.015
Notum CG13076 gene product from transcript CG13076-RB 0.013
cpo couch potato 0.013
Gr64b Gustatory receptor 64b 0.013
qvr quiver 0.012
tim timeless 0.012
Eps-15 Epidermal growth factor receptor pathway substrate clone 15 0.011
ppk19 pickpocket 19 0.011
Msi Male-specific insect derived growth factor 0.010
ds dachsous 0.010
ia2 CG31795 gene product from transcript CG31795-RD 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit 0.986
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.975
Thrb thyroid hormone receptor beta 0.949
Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 0.923
Dlg4 discs, large homolog 4 (Drosophila) 0.858
Scn5a sodium channel, voltage-gated, type V, alpha 0.770
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.764
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.696
Cdh23 cadherin 23 (otocadherin) 0.538
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.528
Gabra2 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 0.517
Ush1g Usher syndrome 1G homolog (human) 0.500
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) 0.478
Ryr2 ryanodine receptor 2, cardiac 0.469
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.434
Gad2 glutamic acid decarboxylase 2 0.422
Slc26a4 solute carrier family 26, member 4 0.416
Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 0.379
Bsn bassoon 0.285
Fosb FBJ osteosarcoma oncogene B 0.264
Gabrg2 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 0.256
Tbx5 T-box 5 0.251
Kcnd2 potassium voltage-gated channel, Shal-related family, member 2 0.239
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.227
Cnr1 cannabinoid receptor 1 (brain) 0.222
B3galt1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 0.219
Edn2 endothelin 2 0.210
Grid2 glutamate receptor, ionotropic, delta 2 0.207
Grm8 glutamate receptor, metabotropic 8 0.203
Pgr progesterone receptor 0.198
Nxph1 neurexophilin 1 0.183
Mmp16 matrix metallopeptidase 16 0.182
Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 0.179
Gjb6 gap junction protein, beta 6 0.177
Foxp2 forkhead box P2 0.176
Tmc1 transmembrane channel-like gene family 1 0.170
Drd2 dopamine receptor D2 0.168
Tbx3 T-box 3 0.164
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.148
Foxn1 forkhead box N1 0.142
Fam83f family with sequence similarity 83, member F 0.140
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.139
Gpr98 G protein-coupled receptor 98 0.129
Cacnb4 calcium channel, voltage-dependent, beta 4 subunit 0.127
Slc12a5 solute carrier family 12, member 5 0.127
Npas1 neuronal PAS domain protein 1 0.124
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.122
Zfpm2 zinc finger protein, multitype 2 0.118
Rorb RAR-related orphan receptor beta 0.114
Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 0.114
Htr5a 5-hydroxytryptamine (serotonin) receptor 5A 0.113
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.109
Shc3 src homology 2 domain-containing transforming protein C3 0.108
Alx3 aristaless-like homeobox 3 0.104
Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.102
Krt72-ps keratin 72, pseudogene 0.092
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.090
Bmp8b bone morphogenetic protein 8b 0.088
Cntn4 contactin 4 0.088
Cntn1 contactin 1 0.087
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.087
Adra1a adrenergic receptor, alpha 1a 0.085
Neurod1 neurogenic differentiation 1 0.085
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.084
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.082
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.082
Grxcr1 glutaredoxin, cysteine rich 1 0.080
Cldn3 claudin 3 0.079
Tjp1 tight junction protein 1 0.075
Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 0.075
Tff2 trefoil factor 2 (spasmolytic protein 1) 0.075
Neto1 neuropilin (NRP) and tolloid (TLL)-like 1 0.070
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 0.070
Col11a1 collagen, type XI, alpha 1 0.070
Gabrb1 gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 0.069
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.067
Scn1a sodium channel, voltage-gated, type I, alpha 0.065
Hcn1 hyperpolarization-activated, cyclic nucleotide-gated K+ 1 0.065
Ptk7 PTK7 protein tyrosine kinase 7 0.065
Sh3gl2 SH3-domain GRB2-like 2 0.062
Cldn6 claudin 6 0.062
Tcfcp2l1 transcription factor CP2-like 1 0.062
Mesp1 mesoderm posterior 1 0.062
Gabrd gamma-aminobutyric acid (GABA) A receptor, subunit delta 0.058
Foxp1 forkhead box P1 0.056
Ush1c Usher syndrome 1C homolog (human) 0.056
Gjb2 gap junction protein, beta 2 0.056
Kif5c kinesin family member 5C 0.056
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.056
Espn espin 0.056
Hand1 heart and neural crest derivatives expressed transcript 1 0.054
Sprr2k small proline-rich protein 2K 0.053
Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 0.053
Lrrtm1 leucine rich repeat transmembrane neuronal 1 0.053
Syt1 synaptotagmin I 0.052
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.051
Pcdh15 protocadherin 15 0.051
Mpz myelin protein zero 0.051
Rit2 Ras-like without CAAX 2 0.050
Col19a1 collagen, type XIX, alpha 1 0.050
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism