The network for 'positive regulation of secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.

Danio rerio
Name Description Probability Func Analog Organism
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.204
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.170
sema3ab semaphorin 3ab 0.146
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.139
ncam2 neural cell adhesion molecule 2 0.138
cnn2 calponin 2 0.136
LOC100003514 protein kinase C alpha type-like 0.125
sb:cb183 sb:cb183 0.124
clgn calmegin 0.118
pob partial optokinetic response b 0.116
caspa caspase a 0.112
pparg peroxisome proliferator activated receptor gamma 0.111
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.102
nod1 nucleotide-binding oligomerization domain containing 1 0.099
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.099
vps39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.098
rhoaa ras homolog gene family, member Aa 0.098
zgc:66382 zgc:66382 0.097
hspb6 heat shock protein, alpha-crystallin-related, b6 0.097
nkx2.2a NK2 transcription factor related 2a 0.097
wu:fb17g07 wu:fb17g07 0.097
acvr2a activin receptor IIa 0.096
si:dkey-20n3.1 si:dkey-20n3.1 0.094
celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 0.094
atp6v1d ATPase, H+ transporting, V1 subunit D and ATPase, H+ transporting, V1 subunit D 0.093
prkcea protein kinase C, epsilon a 0.092
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.092
zgc:103663 zgc:103663 0.091
si:ch211-212m21.5 si:ch211-212m21.5 0.089
isl2a islet2a 0.088
apom apolipoprotein M 0.087
cd63 Cd63 antigen 0.086
si:dkeyp-22b2.3 si:dkeyp-22b2.3 0.086
col15a1b collagen, type XV, alpha 1b 0.086
atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 0.085
egr1 early growth response 1 0.085
mapk3 mitogen-activated protein kinase 3 0.084
efnb2a ephrin B2a 0.083
cd82a CD82 antigen, a 0.081
kiss2 kisspeptin 2 0.080
hcrt hypocretin (orexin) neuropeptide precursor 0.080
igfbp3 insulin-like growth factor binding protein 3 0.079
chmp4b chromatin modifying protein 4B 0.079
stk38l serine/threonine kinase 38 like 0.079
zp3a.2 zona pellucida glycoprotein 3a.2 0.078
unc5b unc-5 homolog B (C. elegans) 0.078
cdkn1a cyclin-dependent kinase inhibitor 1A 0.077
wu:fb63c04 wu:fb63c04 0.077
si:ch1073-204j4.2 si:ch1073-204j4.2 0.077
id2a inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a 0.075
pycard PYD and CARD domain containing 0.074
tectb tectorin beta 0.074
lifrb leukemia inhibitory factor receptor alpha b 0.074
mych myelocytomatosis oncogene homolog 0.074
slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.074
otpb orthopedia homolog b 0.074
gria2b glutamate receptor, ionotropic, AMPA 2b 0.073
zgc:171779 zgc:171779 0.073
fgf20a fibroblast growth factor 20a 0.073
slc14a2 solute carrier family 14 (urea transporter), member 2 0.072
sox2 SRY-box containing gene 2 0.072
cyp11a1 cytochrome P450, subfamily XIA, polypeptide 1 0.071
dcc deleted in colorectal carcinoma 0.071
zgc:64105 zgc:64105 0.071
tubb5 tubulin, beta 5 0.071
htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a 0.071
retsatl retinol saturase (all-trans-retinol 13,14-reductase) like 0.071
sdcbp syndecan binding protein (syntenin) 0.071
rab1a RAB1A, member RAS oncogene family 0.070
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.069
bsg basigin 0.069
pvrl1b poliovirus receptor-related 1b 0.067
hint2 histidine triad nucleotide binding protein 2 0.067
hdac4 histone deacetylase 4 0.067
zgc:55888 zgc:55888 0.067
LOC557072 caspase recruitment domain-containing protein 11-like 0.065
cadm1a cell adhesion molecule 1a 0.065
si:dkey-12o15.1 si:dkey-12o15.1 0.065
adora2b adenosine A2b receptor 0.064
pax7b paired box gene 7b 0.064
chrm2a cholinergic receptor, muscarinic 2a 0.064
myl9l myosin, light polypeptide 9, like 0.064
chat choline acetyltransferase 0.063
paqr8 progestin and adipoQ receptor family member VIII 0.063
acvr2b activin receptor IIb 0.063
birc5b baculoviral IAP repeat-containing 5B 0.063
zgc:77849 zgc:77849 0.063
bc2 putative breast adenocarcinoma marker 0.063
tm4sf4 transmembrane 4 L six family member 4 0.062
esrrga estrogen-related receptor gamma a 0.062
atp6v1c1b ATPase, H+ transporting, lysosomal, V1 subunit C, isoform 1b 0.062
notch3 notch homolog 3 0.062
wu:fc18c07 wu:fc18c07 0.061
krit1 KRIT1, ankyrin repeat containing 0.061
tfe3a transcription factor binding to IGHM enhancer 3a 0.061
actr1 ARP1 actin-related protein 1, centractin (yeast) 0.061
card9 caspase recruitment domain family, member 9 0.061
btbd6b BTB (POZ) domain containing 6b 0.061
tuba8l3 tubulin, alpha 8 like 3 0.061
zgc:65827 zgc:65827 0.060
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
pkg-1 Protein PKG-1 0.374
cyp-35C1 Protein CYP-35C1 0.343
gpb-1 Protein GPB-1 0.315
unc-10 Protein UNC-10 0.183
egl-30 Protein EGL-30 0.178
aex-3 Protein AEX-3 0.138
unc-9 Protein UNC-9 0.111
goa-1 Protein GOA-1 0.099
sol-1 Protein SOL-1 0.097
itr-1 Protein ITR-1 0.093
unc-32 Protein UNC-32 0.079
nrx-1 Protein NRX-1 0.070
aat-5 Protein AAT-5 0.068
cyp-35A2 Protein CYP-35A2 0.059
K05F1.6 Protein K05F1.6 0.056
cmd-1 Protein CMD-1 0.054
gar-2 Protein GAR-2 0.053
lit-1 Protein LIT-1 0.049
F54G2.1 Protein F54G2.1 0.045
tpa-1 Protein TPA-1 0.045
cdc-42 Protein CDC-42 0.043
lin-23 Protein LIN-23 0.043
cyp-35A4 Protein CYP-35A4 0.043
let-607 Protein LET-607 0.043
unc-36 Protein UNC-36 0.043
CELE_C29F7.2 Protein C29F7.2 0.042
abts-3 Protein ABTS-3 0.042
tmc-2 Protein TMC-2 0.040
C33A11.1 Protein C33A11.1 0.038
ist-1 Protein IST-1 0.038
CELE_C08E8.4 Protein C08E8.4 0.037
sgn-1 Protein SGN-1 0.037
cyp-35A3 Protein CYP-35A3 0.037
ZC506.1 Protein ZC506.1 0.036
rol-3 Protein ROL-3 0.032
pqn-18 Protein PQN-18 0.031
unc-43 Protein UNC-43 0.030
frm-3 Protein FRM-3 0.030
snf-1 Protein SNF-1 0.030
daf-11 Protein DAF-11 0.030
trp-1 Protein TRP-1 0.029
unc-41 Protein UNC-41 0.028
myo-6 Protein MYO-6 0.028
pde-4 Protein PDE-4 0.028
vha-13 Protein VHA-13 0.028
ajm-1 Protein AJM-1 0.027
pqn-89 Protein PQN-89 0.027
unc-25 Protein UNC-25 0.026
rpm-1 Protein RPM-1 0.026
eps-8 Protein EPS-8 0.025
unc-80 Protein UNC-80 0.025
unc-77 Protein UNC-77 0.025
unc-47 Protein UNC-47 0.023
sec-10 Protein SEC-10 0.023
lon-2 Protein LON-2 0.023
glr-4 Protein GLR-4 0.022
olrn-1 Protein OLRN-1 0.022
W07B8.3 Protein W07B8.3 0.022
casy-1 Protein CASY-1 0.022
hpl-1 Protein HPL-1 0.022
inx-1 Protein INX-1 0.021
lron-5 Protein LRON-5 0.021
lgc-44 Protein LGC-44 0.021
abcf-2 Protein ABCF-2 0.021
dop-5 Protein DOP-5 0.021
chc-1 Protein CHC-1 0.021
C24A1.3 Protein C24A1.3 0.021
rab-11.1 Protein RAB-11.1 0.021
stim-1 Protein STIM-1 0.021
slo-2 Protein SLO-2 0.020
W01A11.1 Protein W01A11.1 0.020
unc-79 Protein UNC-79 0.020
unc-31 Protein UNC-31 0.020
cpna-1 Protein CPNA-1 0.020
nra-3 Protein NRA-3 0.020
F54C8.7 Protein F54C8.7 0.019
ttyh-1 Protein TTYH-1 0.019
F46C5.4 Protein F46C5.4 0.019
F59E10.3 Protein F59E10.3 0.019
ocr-2 Protein OCR-2 0.019
unc-116 Protein UNC-116 0.019
nlp-6 Protein NLP-6 0.018
nduf-7 Protein NDUF-7 0.018
rme-1 Protein RME-1 0.018
sipa-1 Protein SIPA-1 0.018
ins-1 Protein INS-1 0.018
F59F5.5 Protein F59F5.5 0.018
unc-29 Protein UNC-29 0.018
CELE_F15A8.6 Protein F15A8.6 0.018
F21A3.2 Protein F21A3.2 0.018
grk-2 Protein GRK-2 0.018
eea-1 Protein EEA-1 0.018
eat-4 Protein EAT-4 0.017
CELE_C56A3.6 Protein C56A3.6 0.017
rab-3 Protein RAB-3 0.017
mig-17 Protein MIG-17 0.017
apb-1 Protein APB-1 0.017
C06E7.2 Protein C06E7.2 0.017
sym-4 Protein SYM-4 0.017
inx-19 Protein INX-19 0.017
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Mekk1 CG7717 gene product from transcript CG7717-RB 0.805
hth homothorax 0.705
hep hemipterous 0.690
eca eclair 0.499
dlg1 discs large 1 0.376
par-1 CG8201 gene product from transcript CG8201-RA 0.350
wls wntless 0.339
unc-13 CG2999 gene product from transcript CG2999-RA 0.338
rtGEF rho-type guanine exchange factor 0.331
Rac1 CG2248 gene product from transcript CG2248-RA 0.327
p24-1 p24-related-1 0.309
GluRIIA Glutamate receptor IIA 0.250
dys dysfusion 0.243
Smg1 CG32743 gene product from transcript CG32743-RA 0.231
lqf liquid facets 0.231
Sema-1a CG18405 gene product from transcript CG18405-RD 0.209
Nrx-1 Neurexin 1 0.183
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.181
brp bruchpilot 0.175
Khc-73 Kinesin-73 0.170
sgl sugarless 0.159
neuroligin CG13772 gene product from transcript CG13772-RA 0.159
Rab7 Rab-protein 7 0.155
Src42A Src oncogene at 42A 0.148
CanA1 Calcineurin A1 0.147
wun wunen 0.136
bai baiser 0.128
drk downstream of receptor kinase 0.123
Gyc76C Guanylyl cyclase at 76C 0.122
HDAC6 CG6170 gene product from transcript CG6170-RA 0.121
Moe Moesin 0.118
p24-2 p24-related-2 0.118
Frq2 Frequenin 2 0.112
Ank2 Ankyrin 2 0.111
Pp2B-14D Protein phosphatase 2B at 14D 0.102
grp grapes 0.102
CG34139 CG34139 gene product from transcript CG34139-RD 0.092
Osbp Oxysterol binding protein 0.089
CG11317 CG11317 gene product from transcript CG11317-RA 0.084
sfl sulfateless 0.082
katanin-60 katanin 60 0.081
cher cheerio 0.081
PRL-1 CG4993 gene product from transcript CG4993-RB 0.080
Hs6st Heparan sulfate 6-O-sulfotransferase 0.080
Rac2 CG8556 gene product from transcript CG8556-RA 0.077
stnB stoned B 0.076
G-oalpha47A G protein oalpha 47A 0.073
Pk61C Protein kinase 61C 0.072
vkg viking 0.072
btl breathless 0.070
CG12187 CG12187 gene product from transcript CG12187-RA 0.069
myoglianin CG1838 gene product from transcript CG1838-RD 0.068
AdoR Adenosine receptor 0.061
wit wishful thinking 0.060
lap like-AP180 0.060
sqh spaghetti squash 0.059
Catsup Catecholamines up 0.059
fz2 frizzled 2 0.059
Ork1 Open rectifier K[+] channel 1 0.058
Tl Toll 0.057
SdhA Succinate dehydrogenase A 0.056
Eip63F-1 Ecdysone-induced protein 63F 1 0.056
Hnf4 Hepatocyte nuclear factor 4 0.056
RASSF8 CG5053 gene product from transcript CG5053-RA 0.056
Tango1 Transport and Golgi organization 1 0.055
Rab5 Rab-protein 5 0.055
CG10103 CG10103 gene product from transcript CG10103-RA 0.054
Duox Dual oxidase 0.054
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.053
pnt pointed 0.052
Ace Acetylcholine esterase 0.052
Dat Dopamine N acetyltransferase 0.051
Rop Ras opposite 0.050
CG6191 CG6191 gene product from transcript CG6191-RA 0.049
Rab3 Rab-protein 3 0.049
deltaCOP delta-coatomer protein 0.049
stj straightjacket 0.048
usp ultraspiracle 0.048
bsk basket 0.047
Rab6 Rab-protein 6 0.047
mth methuselah 0.047
Nrt Neurotactin 0.047
endoA endophilin A 0.045
trp transient receptor potential 0.045
fkh fork head 0.044
gcm glial cells missing 0.044
ird1 immune response deficient 1 0.044
BG4 CG12297 gene product from transcript CG12297-RA 0.043
Rab2 Rab-protein 2 0.041
faf fat facets 0.041
ZIP1 Zinc/iron regulated transporter-related protein 1 0.039
stmA stambha A 0.038
CG34400 CG34400 gene product from transcript CG34400-RD 0.038
Snap25 Synapse protein 25 0.037
Tequila CG4821 gene product from transcript CG4821-RE 0.037
cpx complexin 0.036
Syt1 Synaptotagmin 1 0.036
mbc myoblast city 0.035
pgant3 polypeptide GalNAc transferase 3 0.035
sec63 CG8583 gene product from transcript CG8583-RA 0.035
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.946
SH3KBP1 SH3-domain kinase binding protein 1 0.828
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.825
NLRC4 NLR family, CARD domain containing 4 0.723
PSEN1 presenilin 1 0.660
VAMP3 vesicle-associated membrane protein 3 (cellubrevin) 0.657
RAB5A RAB5A, member RAS oncogene family 0.628
FGB fibrinogen beta chain 0.600
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.589
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.577
S100A8 S100 calcium binding protein A8 0.562
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.550
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.535
BTN3A2 butyrophilin, subfamily 3, member A2 0.524
KCNE1 potassium voltage-gated channel, Isk-related family, member 1 0.524
EGFR epidermal growth factor receptor 0.493
INSR insulin receptor 0.487
PSEN2 presenilin 2 (Alzheimer disease 4) 0.451
DRD2 dopamine receptor D2 0.447
TEK TEK tyrosine kinase, endothelial 0.445
OCRL oculocerebrorenal syndrome of Lowe 0.421
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.419
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.417
ARRB1 arrestin, beta 1 0.414
SNAP23 synaptosomal-associated protein, 23kDa 0.411
UBQLN1 ubiquilin 1 0.406
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.396
BTN3A3 butyrophilin, subfamily 3, member A3 0.390
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.389
FYN FYN oncogene related to SRC, FGR, YES 0.386
APP amyloid beta (A4) precursor protein 0.379
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.377
PDCD6IP programmed cell death 6 interacting protein 0.375
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.362
FGA fibrinogen alpha chain 0.352
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.340
S100A9 S100 calcium binding protein A9 0.340
HCK hemopoietic cell kinase 0.340
IL10RA interleukin 10 receptor, alpha 0.332
CCL4 chemokine (C-C motif) ligand 4 0.319
ANG angiogenin, ribonuclease, RNase A family, 5 0.313
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.303
TAL1 T-cell acute lymphocytic leukemia 1 0.303
LAT linker for activation of T cells 0.302
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.294
GBA glucosidase, beta, acid 0.287
CD80 CD80 molecule 0.285
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.279
SNAP25 synaptosomal-associated protein, 25kDa 0.277
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.272
HLA-DRA major histocompatibility complex, class II, DR alpha 0.264
GDI2 GDP dissociation inhibitor 2 0.247
DLG4 discs, large homolog 4 (Drosophila) 0.245
MED28 mediator complex subunit 28 0.235
ADORA2A adenosine A2a receptor 0.233
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.229
RAB14 RAB14, member RAS oncogene family 0.229
LRP1 low density lipoprotein receptor-related protein 1 0.224
BLNK B-cell linker 0.223
IGF1R insulin-like growth factor 1 receptor 0.218
CRHR1 corticotropin releasing hormone receptor 1 0.218
SETD8 SET domain containing (lysine methyltransferase) 8 0.218
FGG fibrinogen gamma chain 0.217
TLR2 toll-like receptor 2 0.214
GDI1 GDP dissociation inhibitor 1 0.210
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.198
BAI1 brain-specific angiogenesis inhibitor 1 0.198
IL4 interleukin 4 0.187
IL1RN interleukin 1 receptor antagonist 0.185
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.184
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.184
CDH5 cadherin 5, type 2 (vascular endothelium) 0.183
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.183
CREBBP CREB binding protein 0.181
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.179
TUBB tubulin, beta 0.179
COL4A1 collagen, type IV, alpha 1 0.179
BTN3A1 butyrophilin, subfamily 3, member A1 0.178
STAMBP STAM binding protein 0.170
CHMP2B chromatin modifying protein 2B 0.169
RAB1A RAB1A, member RAS oncogene family 0.167
LRRK2 leucine-rich repeat kinase 2 0.165
HLA-DMA major histocompatibility complex, class II, DM alpha 0.164
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.163
CD28 CD28 molecule 0.160
MPDZ multiple PDZ domain protein 0.159
ANGPT2 angiopoietin 2 0.157
SDCBP syndecan binding protein (syntenin) 0.156
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 0.154
ABI2 abl-interactor 2 0.153
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.153
KCNQ2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.152
MAP2K4 mitogen-activated protein kinase kinase 4 0.150
ARL8B ADP-ribosylation factor-like 8B 0.149
NCF4 neutrophil cytosolic factor 4, 40kDa 0.144
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.144
EPS15 epidermal growth factor receptor pathway substrate 15 0.144
PECAM1 platelet/endothelial cell adhesion molecule 0.142
DLG1 discs, large homolog 1 (Drosophila) 0.141
RIN1 Ras and Rab interactor 1 0.140
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Mus musculus
Name Description Probability Func Analog Organism
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.998
Drd2 dopamine receptor D2 0.987
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.941
Casp1 caspase 1 0.916
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.884
Il1r1 interleukin 1 receptor, type I 0.860
Tlr4 toll-like receptor 4 0.851
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.833
Kl klotho 0.822
Il1b interleukin 1 beta 0.777
Nf1 neurofibromatosis 1 0.770
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.769
Nos2 nitric oxide synthase 2, inducible 0.767
Nos3 nitric oxide synthase 3, endothelial cell 0.749
Lep leptin 0.733
Tnf tumor necrosis factor 0.692
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.688
Tyrobp TYRO protein tyrosine kinase binding protein 0.680
Btk Bruton agammaglobulinemia tyrosine kinase 0.671
Zeb1 zinc finger E-box binding homeobox 1 0.646
Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) 0.642
Bdkrb2 bradykinin receptor, beta 2 0.612
Rab27a RAB27A, member RAS oncogene family 0.589
Ednrb endothelin receptor type B 0.584
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.562
Mefv Mediterranean fever 0.556
Lta lymphotoxin A 0.542
Prop1 paired like homeodomain factor 1 0.537
Cd22 CD22 antigen 0.532
Gpr33 G protein-coupled receptor 33 0.530
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.528
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.519
Ccl12 chemokine (C-C motif) ligand 12 0.519
Mmp12 matrix metallopeptidase 12 0.518
Ccl22 chemokine (C-C motif) ligand 22 0.517
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.515
S100a4 S100 calcium binding protein A4 0.511
Insm1 insulinoma-associated 1 0.500
Blk B lymphoid kinase 0.496
Ccl2 chemokine (C-C motif) ligand 2 0.495
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.491
Lat linker for activation of T cells 0.489
Cd40 CD40 antigen 0.481
Cd86 CD86 antigen 0.471
Fas Fas (TNF receptor superfamily member 6) 0.470
C3ar1 complement component 3a receptor 1 0.465
Src Rous sarcoma oncogene 0.463
Cd80 CD80 antigen 0.458
Ccr1 chemokine (C-C motif) receptor 1 0.448
Sox4 SRY-box containing gene 4 0.436
Lepr leptin receptor 0.432
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.428
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.427
Ccl6 chemokine (C-C motif) ligand 6 0.427
Ptprc protein tyrosine phosphatase, receptor type, C 0.423
Il3 interleukin 3 0.420
Pitx3 paired-like homeodomain transcription factor 3 0.419
Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like 0.418
Raver2 ribonucleoprotein, PTB-binding 2 0.411
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.405
Ifngr1 interferon gamma receptor 1 0.403
Cckbr cholecystokinin B receptor 0.402
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.388
Fgf23 fibroblast growth factor 23 0.378
Xcr1 chemokine (C motif) receptor 1 0.377
Ren1 renin 1 structural 0.374
Cd5 CD5 antigen 0.371
Cd28 CD28 antigen 0.371
Pdcd1lg2 programmed cell death 1 ligand 2 0.368
Il10 interleukin 10 0.368
Ifng interferon gamma 0.368
Itk IL2-inducible T-cell kinase 0.360
Snap23 synaptosomal-associated protein 23 0.359
Stx4a syntaxin 4A (placental) 0.358
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.358
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.356
C1qc complement component 1, q subcomponent, C chain 0.355
C1qb complement component 1, q subcomponent, beta polypeptide 0.354
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.349
Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 0.344
Rel reticuloendotheliosis oncogene 0.343
C1qa complement component 1, q subcomponent, alpha polypeptide 0.338
S100a6 S100 calcium binding protein A6 (calcyclin) 0.337
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.336
Hrh2 histamine receptor H2 0.336
Has1 hyaluronan synthase1 0.333
Itgax integrin alpha X 0.330
Clec4d C-type lectin domain family 4, member d 0.328
Alox8 arachidonate 8-lipoxygenase 0.323
Ccl8 chemokine (C-C motif) ligand 8 0.322
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.316
Barx2 BarH-like homeobox 2 0.309
Inpp5d inositol polyphosphate-5-phosphatase D 0.309
Ldb3 LIM domain binding 3 0.309
Hif1a hypoxia inducible factor 1, alpha subunit 0.308
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.308
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.306
Gbp5 guanylate binding protein 5 0.303
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.302
Emx1 empty spiracles homolog 1 (Drosophila) 0.301
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Syt4 synaptotagmin IV 0.920
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.762
Gabbr1 gamma-aminobutyric acid (GABA) B receptor 1 0.722
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.700
Chrnb2 cholinergic receptor, nicotinic, beta 2 (neuronal) 0.683
Pde3a phosphodiesterase 3A, cGMP inhibited 0.621
Prss3 protease, serine, 3 0.583
Olr1641 olfactory receptor 1641 0.577
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.569
Apba2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.560
Ncan neurocan 0.549
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.536
S1pr2 sphingosine-1-phosphate receptor 2 0.505
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.503
Clstn3 calsyntenin 3 0.480
Stxbp1 syntaxin binding protein 1 0.478
Fgfr2 fibroblast growth factor receptor 2 0.466
Grik1 glutamate receptor, ionotropic, kainate 1 0.464
Aqp4 aquaporin 4 0.456
Hpcal4 hippocalcin-like 4 0.449
Vom2r53 vomeronasal 2 receptor, 53 0.448
Adra2a adrenergic, alpha-2A-, receptor 0.432
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.429
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.417
Stx1a syntaxin 1A (brain) 0.411
Syn1 synapsin I 0.404
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.404
Psp parotid secretory protein 0.402
Atxn1 ataxin 1 0.390
Kl Klotho 0.382
Zg16 zymogen granule protein 16 0.380
Ppara peroxisome proliferator activated receptor alpha 0.379
Gzmk granzyme K 0.372
Pzp pregnancy-zone protein 0.371
Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 0.363
Htr3a 5-hydroxytryptamine (serotonin) receptor 3a 0.360
Snap25 synaptosomal-associated protein 25 0.359
Vamp2 vesicle-associated membrane protein 2 0.330
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 0.327
Gfra2 GDNF family receptor alpha 2 0.326
Sdc3 syndecan 3 0.322
Apba1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.314
Crhr2 corticotropin releasing hormone receptor 2 0.314
Th tyrosine hydroxylase 0.313
Oprl1 opiate receptor-like 1 0.311
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.301
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.295
Arl11 ADP-ribosylation factor-like 11 0.295
Gabra3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.295
Adam17 ADAM metallopeptidase domain 17 0.292
P2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.291
Ptgfr prostaglandin F receptor 0.287
Nfasc neurofascin 0.283
Phkg1 phosphorylase kinase, gamma 1 0.280
Hoxa1 homeo box A1 0.275
Slc8a3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.273
Rorb RAR-related orphan receptor B 0.272
Syn2 synapsin II 0.272
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.271
Reg3a regenerating islet-derived 3 alpha 0.270
Hcrt hypocretin 0.269
Pcdhb12 protocadherin beta 12 0.268
Gck glucokinase 0.268
Nmnat2 nicotinamide nucleotide adenylyltransferase 2 0.263
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.263
Sst somatostatin 0.259
Prkcg protein kinase C, gamma 0.258
Oprk1 opioid receptor, kappa 1 0.257
Pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.257
Htr2a 5-hydroxytryptamine (serotonin) receptor 2A 0.256
Gfi1 growth factor independent 1 transcription repressor 0.255
Olr1278 olfactory receptor 1278 0.255
Il1b interleukin 1 beta 0.253
Grm6 glutamate receptor, metabotropic 6 0.244
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.241
Cd4 Cd4 molecule 0.240
Fgf8 fibroblast growth factor 8 0.235
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.235
Csk c-src tyrosine kinase 0.235
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.233
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.233
Slco1a1 solute carrier organic anion transporter family, member 1a1 0.230
Rbp3 retinol binding protein 3, interstitial 0.228
Cd79b Cd79b molecule, immunoglobulin-associated beta 0.226
Kcnd3 potassium voltage-gated channel, Shal-related subfamily, member 3 0.224
Rgs9 regulator of G-protein signaling 9 0.222
Tacr1 tachykinin receptor 1 0.222
Avpr1b arginine vasopressin receptor 1B 0.217
Fgf10 fibroblast growth factor 10 0.217
Csf1 colony stimulating factor 1 (macrophage) 0.216
Sstr1 somatostatin receptor 1 0.215
Hrh3 histamine receptor H3 0.215
Fgd4 FYVE, RhoGEF and PH domain containing 4 0.214
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.212
Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 0.209
G6pc glucose-6-phosphatase, catalytic subunit 0.209
Glp1r glucagon-like peptide 1 receptor 0.208
Syp synaptophysin 0.208
Gabrp gamma-aminobutyric acid (GABA-A) receptor, pi 0.207
Tacr2 tachykinin receptor 2 0.207
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ERV25 Erv25p 0.363
ERP4 Erp4p 0.331
ERP5 Erp5p 0.331
SSO1 Sso1p 0.157
CNB1 Cnb1p 0.131
YPT52 Ypt52p 0.117
OLE1 Ole1p 0.105
YPT1 Ypt1p 0.094
SRO7 Sro7p 0.092
SSO2 Sso2p 0.088
YPT10 Ypt10p 0.080
MSO1 Mso1p 0.079
TSL1 Tsl1p 0.076
YFR006W hypothetical protein 0.069
SLM2 Slm2p 0.067
SEC4 Sec4p 0.065
EMP24 Emp24p 0.064
TPS1 Tps1p 0.061
YPT6 Ypt6p 0.061
ZWF1 Zwf1p 0.061
CDC37 Cdc37p 0.058
RHO4 Rho4p 0.057
HXK1 Hxk1p 0.056
ERP3 Erp3p 0.055
IZH4 Izh4p 0.054
ERP6 Erp6p 0.053
CRR1 Crr1p 0.052
SFG1 Sfg1p 0.051
MKT1 Mkt1p 0.050
YPT32 Ypt32p 0.050
RHO1 Rho1p 0.049
YRA1 Yra1p 0.048
CMK1 Cmk1p 0.048
YNL115C hypothetical protein 0.045
RGD1 Rgd1p 0.045
YAP1 Yap1p 0.045
SEC1 Sec1p 0.044
EXO70 Exo70p 0.042
GAL7 Gal7p 0.041
STI1 Sti1p 0.041
CUR1 Cur1p 0.041
ALD4 Ald4p 0.041
SSA3 Ssa3p 0.040
RCN1 Rcn1p 0.040
UNG1 Ung1p 0.040
SGE1 Sge1p 0.040
URA1 Ura1p 0.040
RIM13 Rim13p 0.039
IST1 Ist1p 0.038
PEX30 Pex30p 0.038
CDC10 Cdc10p 0.038
ATG13 Atg13p 0.038
RHO2 Rho2p 0.037
RNR2 Rnr2p 0.037
YLR049C hypothetical protein 0.036
AKR2 Akr2p 0.036
YOL087C hypothetical protein 0.036
CRP1 Crp1p 0.036
PTC3 Ptc3p 0.035
YNL134C hypothetical protein 0.035
YAP7 Yap7p 0.035
BOP2 Bop2p 0.035
SSA4 Ssa4p 0.035
RER1 Rer1p 0.034
DID2 Did2p 0.034
SSE2 Sse2p 0.034
PLB2 Plb2p 0.034
YGR205W hypothetical protein 0.034
SEC9 Sec9p 0.034
SCP1 Scp1p 0.034
ELP6 Elp6p 0.033
SPC1 Spc1p 0.033
YCL042W hypothetical protein 0.033
MER1 Mer1p 0.033
SEC10 Sec10p 0.033
HCH1 Hch1p 0.033
YDL124W hypothetical protein 0.033
UGA2 Uga2p 0.033
NMT1 Nmt1p 0.032
YMR210W hypothetical protein 0.032
TRR1 Trr1p 0.032
HUA2 Hua2p 0.032
MSB3 Msb3p 0.031
PNC1 Pnc1p 0.031
GAD1 Gad1p 0.031
NAB6 Nab6p 0.031
HAL5 Hal5p 0.031
YMR258C hypothetical protein 0.031
GYP7 Gyp7p 0.031
DCS2 Dcs2p 0.031
COQ5 Coq5p 0.031
LCB3 Lcb3p 0.030
GLK1 Glk1p 0.030
ZPR1 Zpr1p 0.030
SWC7 Swc7p 0.030
INP2 Inp2p 0.030
KEL3 Kel3p 0.030
SYS1 Sys1p 0.030
OST2 Ost2p 0.030
VPS13 Vps13p 0.030