Danio rerio

0 known processes

pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

pds5b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic sister chromatid cohesion GO:0007064 2 0.799
Worm
meiotic nuclear division GO:0007126 4 0.434
Worm
sister chromatid cohesion GO:0007062 2 0.386
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.344
stem cell maintenance GO:0019827 4 0.293
negative regulation of histone methylation GO:0031061 1 0.292
cellular aromatic compound metabolic process GO:0006725 295 0.271
meiotic cell cycle process GO:1903046 3 0.238
Worm
nucleic acid metabolic process GO:0090304 244 0.237
larval development GO:0002164 2 0.234
regulation of histone h3 k9 methylation GO:0051570 2 0.227
nucleobase containing compound metabolic process GO:0006139 274 0.180
cell cycle process GO:0022402 53 0.178
Worm
organic substance biosynthetic process GO:1901576 289 0.174
aging GO:0007568 2 0.173
chordate embryonic development GO:0043009 271 0.173
dna metabolic process GO:0006259 27 0.164
regulation of cellular metabolic process GO:0031323 320 0.163
negative regulation of histone modification GO:0031057 1 0.157
nitrogen compound metabolic process GO:0006807 319 0.155
response to amino acid GO:0043200 2 0.146
cellular macromolecule biosynthetic process GO:0034645 224 0.141
histone h3 k9 methylation GO:0051567 5 0.140
regulation of biosynthetic process GO:0009889 250 0.139
negative regulation of dna metabolic process GO:0051053 4 0.132
negative regulation of dna replication GO:0008156 2 0.123
double strand break repair GO:0006302 3 0.120
dna methylation on cytosine GO:0032776 3 0.120
biosynthetic process GO:0009058 294 0.119
regulation of dna replication GO:0006275 3 0.117
embryo development ending in birth or egg hatching GO:0009792 271 0.112
Worm
regulation of primary metabolic process GO:0080090 311 0.111
organic cyclic compound metabolic process GO:1901360 301 0.108
regulation of cellular biosynthetic process GO:0031326 245 0.106
embryonic skeletal system development GO:0048706 97 0.103
regulation of metabolic process GO:0019222 359 0.100
negative regulation of biological process GO:0048519 304 0.096
retina development in camera type eye GO:0060041 146 0.095
nucleic acid templated transcription GO:0097659 181 0.092
nucleobase containing compound biosynthetic process GO:0034654 205 0.092
heterocycle metabolic process GO:0046483 290 0.091
regulation of nitrogen compound metabolic process GO:0051171 251 0.091
cellular macromolecule metabolic process GO:0044260 391 0.091
meiosis i GO:0007127 1 0.091
mitotic cell cycle GO:0000278 64 0.090
Worm
photoreceptor cell differentiation GO:0046530 55 0.087
reproduction GO:0000003 40 0.085
Worm
sister chromatid segregation GO:0000819 6 0.085
Worm
nuclear division GO:0000280 23 0.084
Worm
regulation of gene expression GO:0010468 265 0.080
somitogenesis GO:0001756 87 0.076
cellular component biogenesis GO:0044085 178 0.075
cell cycle GO:0007049 93 0.073
Worm
protein complex biogenesis GO:0070271 30 0.072
neuron projection development GO:0031175 180 0.072
positive regulation of cellular component biogenesis GO:0044089 3 0.072
aromatic compound biosynthetic process GO:0019438 217 0.071
organelle fission GO:0048285 23 0.070
Worm
locomotion GO:0040011 313 0.070
Worm
centrosome organization GO:0051297 1 0.068
localization of cell GO:0051674 244 0.067
gene expression GO:0010467 252 0.063
production of molecular mediator of immune response GO:0002440 2 0.062
branching morphogenesis of a nerve GO:0048755 4 0.061
negative regulation of ras protein signal transduction GO:0046580 1 0.060
eye photoreceptor cell differentiation GO:0001754 45 0.059
negative regulation of cellular biosynthetic process GO:0031327 55 0.057
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.053
meiotic chromosome segregation GO:0045132 3 0.053
Worm
tube morphogenesis GO:0035239 349 0.053
camera type eye development GO:0043010 222 0.052
histone h3 k9 modification GO:0061647 5 0.052
regulation of macromolecule metabolic process GO:0060255 317 0.052
somatic cell dna recombination GO:0016444 1 0.052
macromolecular complex assembly GO:0065003 35 0.052
single organism metabolic process GO:0044710 217 0.051
immunoglobulin production GO:0002377 1 0.051
regulation of establishment of protein localization GO:0070201 4 0.050
cellular biosynthetic process GO:0044249 286 0.050
negative regulation of protein complex assembly GO:0031333 1 0.050
cell motility GO:0048870 244 0.050
microtubule organizing center organization GO:0031023 1 0.050
single organism organelle organization GO:1902589 199 0.049
Worm
negative regulation of cellular process GO:0048523 283 0.049
protein stabilization GO:0050821 2 0.049
regulation of macromolecule biosynthetic process GO:0010556 225 0.048
organelle organization GO:0006996 227 0.047
Worm
ribonucleoside monophosphate catabolic process GO:0009158 4 0.046
protein complex localization GO:0031503 1 0.045
chromosome organization GO:0051276 31 0.045
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.045
cytokinesis GO:0000910 3 0.045
regulation of gene expression epigenetic GO:0040029 11 0.044
regulation of nucleic acid templated transcription GO:1903506 213 0.042
tube closure GO:0060606 1 0.042
cell morphogenesis GO:0000902 289 0.041
embryonic skeletal joint development GO:0072498 3 0.041
macromolecule methylation GO:0043414 19 0.041
mitotic sister chromatid segregation GO:0000070 6 0.041
Worm
regulation of histone methylation GO:0031060 3 0.040
negative regulation of macromolecule metabolic process GO:0010605 76 0.039
histone h3 k4 methylation GO:0051568 2 0.039
double strand break repair via nonhomologous end joining GO:0006303 1 0.038
heterocycle biosynthetic process GO:0018130 215 0.038
cellular component movement GO:0006928 335 0.038
signal transduction GO:0007165 455 0.038
b cell activation GO:0042113 2 0.037
mitotic nuclear division GO:0007067 18 0.037
Worm
cellular component assembly GO:0022607 170 0.037
macromolecular complex subunit organization GO:0043933 74 0.036
negative regulation of chromatin modification GO:1903309 1 0.036
neuron projection morphogenesis GO:0048812 161 0.035
b cell mediated immunity GO:0019724 3 0.035
rna metabolic process GO:0016070 219 0.035
mesenchymal cell proliferation GO:0010463 1 0.034
stem cell proliferation GO:0072089 4 0.034
macromolecule biosynthetic process GO:0009059 227 0.034
ras protein signal transduction GO:0007265 7 0.034
male meiosis GO:0007140 2 0.033
microtubule based process GO:0007017 60 0.032
intracellular mrna localization GO:0008298 1 0.032
regulation of dna recombination GO:0000018 2 0.031
somite development GO:0061053 96 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.031
cell migration GO:0016477 237 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
Worm
maintenance of location GO:0051235 4 0.030
regulation of protein complex assembly GO:0043254 3 0.030
rna biosynthetic process GO:0032774 181 0.030
regulation of rna metabolic process GO:0051252 224 0.030
regulation of apoptotic process GO:0042981 98 0.030
cell projection organization GO:0030030 284 0.029
internal peptidyl lysine acetylation GO:0018393 2 0.029
positive regulation of catabolic process GO:0009896 4 0.029
macromolecule modification GO:0043412 111 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
regulation of cell activation GO:0050865 1 0.028
immunoglobulin mediated immune response GO:0016064 3 0.028
small gtpase mediated signal transduction GO:0007264 8 0.028
protein complex subunit organization GO:0071822 46 0.027
embryonic skeletal joint morphogenesis GO:0060272 3 0.027
single organism localization GO:1902578 225 0.027
regulation of developmental process GO:0050793 247 0.027
Worm
response to uv GO:0009411 3 0.027
digestive system development GO:0055123 289 0.027
retina morphogenesis in camera type eye GO:0060042 79 0.027
neuroblast proliferation GO:0007405 2 0.026
signal transduction by p53 class mediator GO:0072331 13 0.026
homeostasis of number of cells within a tissue GO:0048873 4 0.026
morphogenesis of an epithelium GO:0002009 333 0.025
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
digestive tract development GO:0048565 265 0.024
positive regulation of cell activation GO:0050867 1 0.024
cellular protein metabolic process GO:0044267 129 0.024
central nervous system development GO:0007417 387 0.023
protein alkylation GO:0008213 13 0.023
dna alkylation GO:0006305 8 0.023
generation of neurons GO:0048699 385 0.023
protein complex assembly GO:0006461 30 0.023
pharyngeal system development GO:0060037 18 0.022
spindle assembly GO:0051225 2 0.022
embryonic skeletal system morphogenesis GO:0048704 93 0.022
negative regulation of cell cycle process GO:0010948 9 0.022
eye development GO:0001654 277 0.022
dna methylation GO:0006306 8 0.021
nuclear transport GO:0051169 4 0.021
atp catabolic process GO:0006200 4 0.021
sexual reproduction GO:0019953 36 0.021
skeletal system development GO:0001501 181 0.021
neuron differentiation GO:0030182 353 0.021
intracellular signal transduction GO:0035556 85 0.021
primary neural tube formation GO:0014020 1 0.021
neuron development GO:0048666 262 0.021
organelle assembly GO:0070925 110 0.020
positive regulation of chromosome organization GO:2001252 1 0.020
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.020
rna localization GO:0006403 4 0.020
cell part morphogenesis GO:0032990 246 0.020
germ cell development GO:0007281 22 0.020
regulation of protein catabolic process GO:0042176 1 0.019
neural retina development GO:0003407 49 0.019
neural crest formation GO:0014029 14 0.019
multi organism process GO:0051704 134 0.019
regulation of organelle assembly GO:1902115 4 0.019
meiotic cell cycle GO:0051321 5 0.019
Worm
camera type eye photoreceptor cell differentiation GO:0060219 19 0.019
neuron cellular homeostasis GO:0070050 3 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.018
regulation of production of molecular mediator of immune response GO:0002700 1 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.018
transcription from rna polymerase ii promoter GO:0006366 80 0.018
nucleoside monophosphate catabolic process GO:0009125 4 0.018
exocrine pancreas development GO:0031017 28 0.018
chromosome segregation GO:0007059 12 0.018
Worm
retina layer formation GO:0010842 24 0.018
positive regulation of gene expression GO:0010628 71 0.017
blood vessel development GO:0001568 246 0.017
gene silencing GO:0016458 4 0.017
regulation of cellular protein metabolic process GO:0032268 52 0.017
chromosome organization involved in meiosis GO:0070192 1 0.017
Worm
cellular macromolecular complex assembly GO:0034622 24 0.017
eye morphogenesis GO:0048592 144 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.017
multicellular organism reproduction GO:0032504 35 0.017
developmental growth GO:0048589 166 0.017
Worm
microtubule cytoskeleton organization GO:0000226 33 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
neural tube development GO:0021915 62 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
positive regulation of chromatin modification GO:1903310 1 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.017
negative regulation of nuclear division GO:0051784 3 0.017
embryonic cranial skeleton morphogenesis GO:0048701 90 0.016
head development GO:0060322 303 0.016
cell recognition GO:0008037 19 0.016
regulation of chondrocyte differentiation GO:0032330 1 0.016
photoreceptor cell development GO:0042461 40 0.016
stem cell differentiation GO:0048863 117 0.016
mitotic cell cycle process GO:1903047 48 0.016
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
tissue homeostasis GO:0001894 25 0.016
eye photoreceptor cell development GO:0042462 30 0.016
forebrain neuron fate commitment GO:0021877 1 0.016
single organism reproductive process GO:0044702 40 0.016
Worm
carboxylic acid metabolic process GO:0019752 22 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
regulation of gene silencing GO:0060968 1 0.015
cardiac atrium morphogenesis GO:0003209 2 0.015
cell substrate adhesion GO:0031589 4 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
meiotic spindle organization GO:0000212 1 0.015
negative regulation of dna recombination GO:0045910 2 0.015
death GO:0016265 121 0.015
chromatin modification GO:0016568 21 0.015
negative regulation of metabolic process GO:0009892 86 0.015
positive regulation of histone modification GO:0031058 1 0.015
sensory organ development GO:0007423 393 0.015
tissue remodeling GO:0048771 4 0.015
amino acid transport GO:0006865 2 0.015
b cell differentiation GO:0030183 1 0.014
sensory organ morphogenesis GO:0090596 200 0.014
melanocyte differentiation GO:0030318 26 0.014
protein acylation GO:0043543 3 0.014
histone lysine methylation GO:0034968 12 0.014
regulation of catalytic activity GO:0050790 55 0.014
mesoderm formation GO:0001707 43 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regionalization GO:0003002 274 0.014
positive regulation of metabolic process GO:0009893 108 0.014
cellular protein catabolic process GO:0044257 4 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
mesoderm development GO:0007498 88 0.014
regulation of dendrite development GO:0050773 3 0.013
cytoskeleton organization GO:0007010 96 0.013
non recombinational repair GO:0000726 2 0.013
protein modification process GO:0036211 100 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
glial cell proliferation GO:0014009 4 0.013
spermatid development GO:0007286 2 0.013
regulation of cell differentiation GO:0045595 142 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
gastrulation GO:0007369 208 0.013
regulation of neuron migration GO:2001222 2 0.013
centrosome duplication GO:0051298 1 0.013
protein methylation GO:0006479 13 0.013
regulation of mitotic cell cycle GO:0007346 25 0.013
lateral line system development GO:0048925 76 0.013
determination of ventral identity GO:0048264 21 0.013
proteasomal protein catabolic process GO:0010498 2 0.012
immune system development GO:0002520 191 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
regulation of reproductive process GO:2000241 4 0.012
digestive tract morphogenesis GO:0048546 231 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
limb bud formation GO:0060174 2 0.012
stem cell development GO:0048864 82 0.012
response to stress GO:0006950 263 0.012
polarized epithelial cell differentiation GO:0030859 4 0.012
cell death GO:0008219 121 0.012
dna methylation or demethylation GO:0044728 8 0.012
dna biosynthetic process GO:0071897 3 0.012
activation of mapk activity GO:0000187 3 0.012
negative regulation of developmental process GO:0051093 65 0.012
oocyte anterior posterior axis specification GO:0007314 4 0.012
regulation of pigment cell differentiation GO:0050932 2 0.012
regulation of mrna catabolic process GO:0061013 3 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
positive regulation of epithelial cell differentiation GO:0030858 2 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
hatching GO:0035188 4 0.012
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.012
embryonic organ morphogenesis GO:0048562 274 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
positive regulation of cell cycle GO:0045787 3 0.011
regulation of cell shape GO:0008360 1 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
axon development GO:0061564 166 0.011
regulation of mesenchymal cell proliferation GO:0010464 1 0.011
positive regulation of dna templated transcription elongation GO:0032786 1 0.011
anatomical structure homeostasis GO:0060249 36 0.011
regulation of oocyte development GO:0060281 3 0.011
somatic muscle development GO:0007525 4 0.011
cellular response to nutrient levels GO:0031669 2 0.011
segmentation GO:0035282 97 0.011
spermatid differentiation GO:0048515 2 0.011
covalent chromatin modification GO:0016569 20 0.011
establishment of localization GO:0051234 244 0.011
Worm
cognition GO:0050890 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
cardiac atrium development GO:0003230 4 0.011
regulation of cell fate specification GO:0042659 20 0.011
exocrine system development GO:0035272 28 0.011
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.010
regulation of synapse assembly GO:0051963 3 0.010
positive regulation of immune effector process GO:0002699 3 0.010
embryonic pattern specification GO:0009880 44 0.010
regulation of jak stat cascade GO:0046425 3 0.010
negative regulation of cell differentiation GO:0045596 46 0.010
muscle organ development GO:0007517 101 0.010
regulation of melanocyte differentiation GO:0045634 2 0.010
reproductive process GO:0022414 40 0.010
Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
regulation of cell communication GO:0010646 232 0.010
camera type eye morphogenesis GO:0048593 108 0.010
regulation of cellular component organization GO:0051128 86 0.010

pds5b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
retinal disease DOID:5679 0 0.015
eye disease DOID:5614 0 0.015
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
organ system cancer DOID:0050686 0 0.013