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Process View

Homo sapiens

1 genes annotated in human

cell competition in a multicellular organism

Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell competition in a multicellular organism"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell competition in a multicellular organism" (in gray)

Name	Description	Probability	Func Analog Organism
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.999
WIPF1	WAS/WASL interacting protein family, member 1	0.959
DDB1	damage-specific DNA binding protein 1, 127kDa	0.928
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.833	Fly
NCF2	neutrophil cytosolic factor 2	0.705
ELMO1	engulfment and cell motility 1	0.668
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.641
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.566
SH3RF3	SH3 domain containing ring finger 3	0.517
AMOTL2	angiomotin like 2	0.363
CHN2	chimerin (chimaerin) 2	0.352
ZCCHC17	zinc finger, CCHC domain containing 17	0.312
NCK2	NCK adaptor protein 2	0.293
ARHGAP15	Rho GTPase activating protein 15	0.255
DEF6	differentially expressed in FDCP 6 homolog (mouse)	0.245
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.234
BTRC	beta-transducin repeat containing	0.219
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.188
CUL4A	cullin 4A	0.182
SH3RF1	SH3 domain containing ring finger 1	0.182
TJP1	tight junction protein 1 (zona occludens 1)	0.168
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.152
ADAM15	ADAM metallopeptidase domain 15	0.139
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.124
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.121
BRD4	bromodomain containing 4	0.114
CTTN	cortactin	0.107
AMOTL1	angiomotin like 1	0.104
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.097
OCRL	oculocerebrorenal syndrome of Lowe	0.096
TJP2	tight junction protein 2 (zona occludens 2)	0.095
PRPF38A	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	0.090
WASL	Wiskott-Aldrich syndrome-like	0.078	Fly
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.072
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.067
NCKAP1	NCK-associated protein 1	0.066
FHOD1	formin homology 2 domain containing 1	0.063
SNX33	sorting nexin 33	0.062
DOCK2	dedicator of cytokinesis 2	0.044	Fly
PRKCQ	protein kinase C, theta	0.036
GJA1	gap junction protein, alpha 1, 43kDa	0.034
COTL1	coactosin-like 1 (Dictyostelium)	0.028
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.027
LIMS1	LIM and senescent cell antigen-like domains 1	0.027
CIB1	calcium and integrin binding 1 (calmyrin)	0.026
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.026	Fly
DDB2	damage-specific DNA binding protein 2, 48kDa	0.026
MPDZ	multiple PDZ domain protein	0.026
KPNA6	karyopherin alpha 6 (importin alpha 7)	0.024
TEAD3	TEA domain family member 3	0.024
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.024
AMOT	angiomotin	0.021
CORO1A	coronin, actin binding protein, 1A	0.020
PSEN2	presenilin 2 (Alzheimer disease 4)	0.019
UNKL	unkempt homolog (Drosophila)-like	0.018
SNX9	sorting nexin 9	0.018
TEAD4	TEA domain family member 4	0.018
CCNL1	cyclin L1	0.018
RTKN	rhotekin	0.017
BAIAP2	BAI1-associated protein 2	0.017
NCF1	neutrophil cytosolic factor 1	0.016
PRKCI	protein kinase C, iota	0.016
DHX38	DEAH (Asp-Glu-Ala-His) box polypeptide 38	0.014
KLF5	Kruppel-like factor 5 (intestinal)	0.014
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.014
GNG12	guanine nucleotide binding protein (G protein), gamma 12	0.014
STK10	serine/threonine kinase 10	0.014
FXYD5	FXYD domain containing ion transport regulator 5	0.014
BTN3A2	butyrophilin, subfamily 3, member A2	0.014
DDIT4	DNA-damage-inducible transcript 4	0.014
ARL2BP	ADP-ribosylation factor-like 2 binding protein	0.013
SET	SET nuclear oncogene	0.013
RIPK2	receptor-interacting serine-threonine kinase 2	0.013
HDAC4	histone deacetylase 4	0.013
RAI14	retinoic acid induced 14	0.013
NFIL3	nuclear factor, interleukin 3 regulated	0.013
CCNT1	cyclin T1	0.012
C17orf97	chromosome 17 open reading frame 97	0.012
DLG5	discs, large homolog 5 (Drosophila)	0.012
CHERP	calcium homeostasis endoplasmic reticulum protein	0.012
JUP	junction plakoglobin	0.012
DOCK1	dedicator of cytokinesis 1	0.012	Fly
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.012	Fly
DHX8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	0.012
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.011
TM4SF1	transmembrane 4 L six family member 1	0.011
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.011
NKAP	NFKB activating protein	0.011
WASF2	WAS protein family, member 2	0.011
EFHD2	EF-hand domain family, member D2	0.011
SYNJ2	synaptojanin 2	0.011
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.011
RASAL2	RAS protein activator like 2	0.011
FERMT2	fermitin family member 2	0.010
FLNB	filamin B, beta	0.010
RTN4	reticulon 4	0.010
CALD1	caldesmon 1	0.010
INO80	INO80 homolog (S. cerevisiae)	0.010