IMP

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Homo sapiens

22 genes annotated in human

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hormone mediated signaling pathway

GO:0009755

A series of molecular signals mediated by the detection of a hormone.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hormone mediated signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "hormone mediated signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
ESR1	estrogen receptor 1	1.000
RXRA	retinoid X receptor, alpha	0.995
NCOA1	nuclear receptor coactivator 1	0.990
CREBBP	CREB binding protein	0.972
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.919
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.824	Human
INSR	insulin receptor	0.801
RARA	retinoic acid receptor, alpha	0.763	Human
AR	androgen receptor	0.737
NCOA3	nuclear receptor coactivator 3	0.727
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.690
BMPR1A	bone morphogenetic protein receptor, type IA	0.544
GHR	growth hormone receptor	0.468	Rat
MPDZ	multiple PDZ domain protein	0.360
NCOA2	nuclear receptor coactivator 2	0.357
KLHL24	kelch-like 24 (Drosophila)	0.338
NCOR2	nuclear receptor corepressor 2	0.329
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.232
CRHR1	corticotropin releasing hormone receptor 1	0.223	Rat Fly
STAT5A	signal transducer and activator of transcription 5A	0.221	Mouse
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.191
CRH	corticotropin releasing hormone	0.161	Rat
MED25	mediator complex subunit 25	0.160
EP300	E1A binding protein p300	0.144
HNF4A	hepatocyte nuclear factor 4, alpha	0.144
ESR2	estrogen receptor 2 (ER beta)	0.143	Human Zebrafish Rat
SH2B1	SH2B adaptor protein 1	0.123
BMPR1B	bone morphogenetic protein receptor, type IB	0.112
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.090
IRS1	insulin receptor substrate 1	0.085
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.076
IFNGR1	interferon gamma receptor 1	0.071
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.067
NCOR1	nuclear receptor corepressor 1	0.063
IGF1R	insulin-like growth factor 1 receptor	0.060
FSTL1	follistatin-like 1	0.059
FOXO1	forkhead box O1	0.055
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.053
C16orf53	chromosome 16 open reading frame 53	0.051
NCOA6	nuclear receptor coactivator 6	0.047
PPARA	peroxisome proliferator-activated receptor alpha	0.047
ZFYVE9	zinc finger, FYVE domain containing 9	0.047
NOG	noggin	0.045
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.043
PGR	progesterone receptor	0.043	Zebrafish Mouse Rat
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.042	Zebrafish Mouse
HIC1	hypermethylated in cancer 1	0.041
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.040
JUB	jub, ajuba homolog (Xenopus laevis)	0.039
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.035	Mouse
CAV1	caveolin 1, caveolae protein, 22kDa	0.034
PPP5C	protein phosphatase 5, catalytic subunit	0.030
SSTR2	somatostatin receptor 2	0.030	Human Mouse Rat
JDP2	Jun dimerization protein 2	0.029
SPDEF	SAM pointed domain containing ets transcription factor	0.029
SOCS1	suppressor of cytokine signaling 1	0.029
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.028
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.028
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.028
STK3	serine/threonine kinase 3	0.027
IRS2	insulin receptor substrate 2	0.025
GRIP1	glutamate receptor interacting protein 1	0.024
SNAI1	snail homolog 1 (Drosophila)	0.024
STAP2	signal transducing adaptor family member 2	0.023
GRB10	growth factor receptor-bound protein 10	0.023
PROX1	prospero homeobox 1	0.022
AMOTL1	angiomotin like 1	0.022
LAT	linker for activation of T cells	0.021
MYLK2	myosin light chain kinase 2	0.021
JAK2	Janus kinase 2	0.021	Rat
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.021
EPOR	erythropoietin receptor	0.020
CUEDC2	CUE domain containing 2	0.020
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.018
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.018
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.018
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.018
PTPRB	protein tyrosine phosphatase, receptor type, B	0.018
SFN	stratifin	0.017
STK38L	serine/threonine kinase 38 like	0.017
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.016
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.015
KANK2	KN motif and ankyrin repeat domains 2	0.015
KAT2B	K(lysine) acetyltransferase 2B	0.014
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.014
PRL	prolactin	0.014
ITGA1	integrin, alpha 1	0.014
NRIP1	nuclear receptor interacting protein 1	0.014
AMOT	angiomotin	0.014
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.014
MED13L	mediator complex subunit 13-like	0.013
MED1	mediator complex subunit 1	0.013
CALCA	calcitonin-related polypeptide alpha	0.013
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.013
LIMD1	LIM domains containing 1	0.013
GLIS2	GLIS family zinc finger 2	0.013
RICTOR	RPTOR independent companion of MTOR, complex 2	0.013
BMP4	bone morphogenetic protein 4	0.013
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.013
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.013
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.013
BCR	breakpoint cluster region	0.012
ANKRD28	ankyrin repeat domain 28	0.012
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.012
PPARG	peroxisome proliferator-activated receptor gamma	0.012	Human
RXRB	retinoid X receptor, beta	0.012
MXI1	MAX interactor 1	0.012
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.012
BTRC	beta-transducin repeat containing	0.012
BCAR1	breast cancer anti-estrogen resistance 1	0.012
SOCS3	suppressor of cytokine signaling 3	0.012
PNRC2	proline-rich nuclear receptor coactivator 2	0.012
RXRG	retinoid X receptor, gamma	0.011
YAP1	Yes-associated protein 1	0.011
FGF4	fibroblast growth factor 4	0.011
MTA2	metastasis associated 1 family, member 2	0.011
HIPK2	homeodomain interacting protein kinase 2	0.011
CRHR2	corticotropin releasing hormone receptor 2	0.011	Rat Fly
GAB1	GRB2-associated binding protein 1	0.011
PPP6C	protein phosphatase 6, catalytic subunit	0.010
TCF4	transcription factor 4	0.010
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.010
LTK	leukocyte receptor tyrosine kinase	0.010
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.010	Human Mouse