IMP

Process View

Homo sapiens

14 genes annotated in human

Multi-species View

regulation of phospholipase c activity

GO:1900274

Any process that modulates the frequency, rate or extent of phospholipase C activity.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of phospholipase c activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of phospholipase c activity" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000	Human
FGF1	fibroblast growth factor 1 (acidic)	1.000	Human
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.986
PLCG1	phospholipase C, gamma 1	0.861
MPDZ	multiple PDZ domain protein	0.860
SPRR2A	small proline-rich protein 2A	0.843
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.808
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.806
ANG	angiogenin, ribonuclease, RNase A family, 5	0.726
RNASE4	ribonuclease, RNase A family, 4	0.654	Human
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.620
FGF10	fibroblast growth factor 10	0.583	Human
SOS1	son of sevenless homolog 1 (Drosophila)	0.550
FGFR1	fibroblast growth factor receptor 1	0.497
VEGFA	vascular endothelial growth factor A	0.448
FRS2	fibroblast growth factor receptor substrate 2	0.411
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.370
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.349
BCAR1	breast cancer anti-estrogen resistance 1	0.340
FYB	FYN binding protein	0.259
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.229
LAT	linker for activation of T cells	0.197
FGF7	fibroblast growth factor 7	0.189	Human
ARRB1	arrestin, beta 1	0.189
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.186
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.185
EGFR	epidermal growth factor receptor	0.173
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.134
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.123
ARRDC3	arrestin domain containing 3	0.104
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.103
MAPT	microtubule-associated protein tau	0.090
KITLG	KIT ligand	0.087
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.087	Human
CDH5	cadherin 5, type 2 (vascular endothelium)	0.064
SOS2	son of sevenless homolog 2 (Drosophila)	0.061
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.057
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.056	Human
PGF	placental growth factor	0.055
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.051
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.050
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.050
KRT8	keratin 8	0.046
FYN	FYN oncogene related to SRC, FGR, YES	0.046
NIN	ninein (GSK3B interacting protein)	0.044
GSK3B	glycogen synthase kinase 3 beta	0.042
FGFR3	fibroblast growth factor receptor 3	0.041	Human
GAB1	GRB2-associated binding protein 1	0.040
FLT4	fms-related tyrosine kinase 4	0.040	Human
HPGDS	hematopoietic prostaglandin D synthase	0.039
HSPG2	heparan sulfate proteoglycan 2	0.037
CPA3	carboxypeptidase A3 (mast cell)	0.035
SLA	Src-like-adaptor	0.035
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.033
HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	0.031
CTGF	connective tissue growth factor	0.031
AGTR1	angiotensin II receptor, type 1	0.031
SHANK3	SH3 and multiple ankyrin repeat domains 3	0.030
HDC	histidine decarboxylase	0.030
RNH1	ribonuclease/angiogenin inhibitor 1	0.030
SHB	Src homology 2 domain containing adaptor protein B	0.028
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.028
SELE	selectin E	0.028
GRAP2	GRB2-related adaptor protein 2	0.027
PTEN	phosphatase and tensin homolog	0.026
LDLR	low density lipoprotein receptor	0.025
CCR2	chemokine (C-C motif) receptor 2	0.021
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.021
MAP2	microtubule-associated protein 2	0.019
PDGFA	platelet-derived growth factor alpha polypeptide	0.019
RIN1	Ras and Rab interactor 1	0.019
RET	ret proto-oncogene	0.019
RNASE3	ribonuclease, RNase A family, 3	0.019	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.019
PRKCQ	protein kinase C, theta	0.019
FGF8	fibroblast growth factor 8 (androgen-induced)	0.018
MPO	myeloperoxidase	0.018
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.018
GPR171	G protein-coupled receptor 171	0.017
CTSG	cathepsin G	0.017
VAV1	vav 1 guanine nucleotide exchange factor	0.017
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.016
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.015
MAPK8	mitogen-activated protein kinase 8	0.014
ADRB3	adrenergic, beta-3-, receptor	0.014	Human
FASLG	Fas ligand (TNF superfamily, member 6)	0.013
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.013
MAPK10	mitogen-activated protein kinase 10	0.013
NOSTRIN	nitric oxide synthase trafficker	0.013
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.012	Human
CCR3	chemokine (C-C motif) receptor 3	0.012
GHRHR	growth hormone releasing hormone receptor	0.012
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.012
DARC	Duffy blood group, chemokine receptor	0.011
PDGFC	platelet derived growth factor C	0.011
GPR6	G protein-coupled receptor 6	0.011
EFS	embryonal Fyn-associated substrate	0.011
ADORA3	adenosine A3 receptor	0.011
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.011
PGR	progesterone receptor	0.010
SSTR3	somatostatin receptor 3	0.010
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.010
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.010
ZP2	zona pellucida glycoprotein 2 (sperm receptor)	0.010