IMP

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Homo sapiens

2 genes annotated in human

wnt signaling pathway calcium modulating pathway

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).

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Known genes in the process in human Include functional analogs

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Gene Predictions

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Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "wnt signaling pathway calcium modulating pathway" (in gray)

Name	Description	Probability	Func Analog Organism
BBS10	Bardet-Biedl syndrome 10	1.000
FZD1	frizzled homolog 1 (Drosophila)	0.963	Human
LRP6	low density lipoprotein receptor-related protein 6	0.961
WNT5A	wingless-type MMTV integration site family, member 5A	0.951
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.785
ELF5	E74-like factor 5 (ets domain transcription factor)	0.738
NDP	Norrie disease (pseudoglioma)	0.677
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.495
FZD8	frizzled homolog 8 (Drosophila)	0.425	Human
MXRA5	matrix-remodelling associated 5	0.384
SFRP1	secreted frizzled-related protein 1	0.282
EHF	ets homologous factor	0.226
FOXF2	forkhead box F2	0.187
C7orf36	chromosome 7 open reading frame 36	0.149
DPY19L4	dpy-19-like 4 (C. elegans)	0.139
OGN	osteoglycin	0.127
POSTN	periostin, osteoblast specific factor	0.084
COL5A1	collagen, type V, alpha 1	0.083
GPR124	G protein-coupled receptor 124	0.082
SDC2	syndecan 2	0.081
PDGFC	platelet derived growth factor C	0.081
PLXDC1	plexin domain containing 1	0.077
FZD7	frizzled homolog 7 (Drosophila)	0.070	Human
COL1A2	collagen, type I, alpha 2	0.066
WNT3A	wingless-type MMTV integration site family, member 3A	0.063	Human
TWIST1	twist homolog 1 (Drosophila)	0.058
CXCL14	chemokine (C-X-C motif) ligand 14	0.057
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.053
BMP4	bone morphogenetic protein 4	0.053
GLT8D2	glycosyltransferase 8 domain containing 2	0.050
BMPR1A	bone morphogenetic protein receptor, type IA	0.049
LRRC17	leucine rich repeat containing 17	0.042
GPC4	glypican 4	0.041
RGS2	regulator of G-protein signaling 2, 24kDa	0.040
WNT3	wingless-type MMTV integration site family, member 3	0.040
THBS2	thrombospondin 2	0.039
OMD	osteomodulin	0.037
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.037
FOXF1	forkhead box F1	0.036
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.035
KCNE4	potassium voltage-gated channel, Isk-related family, member 4	0.035
DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	0.034
FZD6	frizzled homolog 6 (Drosophila)	0.033	Human
MFN1	mitofusin 1	0.032
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.032
TRIM32	tripartite motif containing 32	0.032
COL5A2	collagen, type V, alpha 2	0.032
ZNF746	zinc finger protein 746	0.031
PTK2	PTK2 protein tyrosine kinase 2	0.030
WNT2	wingless-type MMTV integration site family member 2	0.030
SFRP2	secreted frizzled-related protein 2	0.030
ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	0.029
MIB1	mindbomb homolog 1 (Drosophila)	0.028
MN1	meningioma (disrupted in balanced translocation) 1	0.028
TWSG1	twisted gastrulation homolog 1 (Drosophila)	0.028
COL11A1	collagen, type XI, alpha 1	0.027
NCKAP1	NCK-associated protein 1	0.027
ASPN	asporin	0.027
FBLN1	fibulin 1	0.027
INHBB	inhibin, beta B	0.027
SOX9	SRY (sex determining region Y)-box 9	0.026
WISP1	WNT1 inducible signaling pathway protein 1	0.026
IGF1	insulin-like growth factor 1 (somatomedin C)	0.026
GAS1	growth arrest-specific 1	0.026
COL1A1	collagen, type I, alpha 1	0.026
LMOD1	leiomodin 1 (smooth muscle)	0.025
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.025
DRD4	dopamine receptor D4	0.025
COL14A1	collagen, type XIV, alpha 1	0.025
OLFML3	olfactomedin-like 3	0.024
PSEN2	presenilin 2 (Alzheimer disease 4)	0.024
PRKCI	protein kinase C, iota	0.023
ACVR1	activin A receptor, type I	0.023
RAI2	retinoic acid induced 2	0.023
NMD3	NMD3 homolog (S. cerevisiae)	0.023
MGP	matrix Gla protein	0.022
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.022
ROR1	receptor tyrosine kinase-like orphan receptor 1	0.021
GSK3B	glycogen synthase kinase 3 beta	0.021
C7	complement component 7	0.021
C19orf46	chromosome 19 open reading frame 46	0.021
MFAP5	microfibrillar associated protein 5	0.021
EDNRA	endothelin receptor type A	0.021
ZCCHC24	zinc finger, CCHC domain containing 24	0.021
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.021
BMP2	bone morphogenetic protein 2	0.021
SOX17	SRY (sex determining region Y)-box 17	0.020
DLG1	discs, large homolog 1 (Drosophila)	0.020
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.020
BMP7	bone morphogenetic protein 7	0.020
ZNF423	zinc finger protein 423	0.020
PERP	PERP, TP53 apoptosis effector	0.020
DSG2	desmoglein 2	0.019
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.019	Mouse
PRRX1	paired related homeobox 1	0.019
MXRA8	matrix-remodelling associated 8	0.019
LRRC15	leucine rich repeat containing 15	0.019
UBQLN4	ubiquilin 4	0.019
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.019
SOCS5	suppressor of cytokine signaling 5	0.019
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.019
PENK	proenkephalin	0.018
GPR125	G protein-coupled receptor 125	0.018
NET1	neuroepithelial cell transforming 1	0.018
FLRT2	fibronectin leucine rich transmembrane protein 2	0.018
ANGPTL2	angiopoietin-like 2	0.018
COL6A3	collagen, type VI, alpha 3	0.018
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.017
FOXC1	forkhead box C1	0.017
HK2	hexokinase 2	0.017
COL10A1	collagen, type X, alpha 1	0.017
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	0.017
ANGPT1	angiopoietin 1	0.017
SNAI2	snail homolog 2 (Drosophila)	0.017
LUM	lumican	0.017
ADAM12	ADAM metallopeptidase domain 12	0.017
TRIL	TLR4 interactor with leucine-rich repeats	0.017
RYK	RYK receptor-like tyrosine kinase	0.016	Zebrafish
SEMA3G	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G	0.016
WIF1	WNT inhibitory factor 1	0.016
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.016
TLX3	T-cell leukemia homeobox 3	0.015
TRAM1	translocation associated membrane protein 1	0.015
COL4A6	collagen, type IV, alpha 6	0.015
CSNK1E	casein kinase 1, epsilon	0.015
WASF3	WAS protein family, member 3	0.015
HOXC6	homeobox C6	0.015
HOXC5	homeobox C5	0.015
FRZB	frizzled-related protein	0.015	Human
MFAP4	microfibrillar-associated protein 4	0.015
PLS3	plastin 3	0.015
BBS7	Bardet-Biedl syndrome 7	0.015
WNT10B	wingless-type MMTV integration site family, member 10B	0.014
SCG5	secretogranin V (7B2 protein)	0.014
SULF1	sulfatase 1	0.014
NPTX2	neuronal pentraxin II	0.014
ABI3BP	ABI family, member 3 (NESH) binding protein	0.014
RGS5	regulator of G-protein signaling 5	0.014
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.014
JAG1	jagged 1	0.014
CHRDL1	chordin-like 1	0.014
OLFML2B	olfactomedin-like 2B	0.014
COL21A1	collagen, type XXI, alpha 1	0.014
ITPRIPL1	inositol 1,4,5-trisphosphate receptor interacting protein-like 1	0.014
ITIH5	inter-alpha (globulin) inhibitor H5	0.014
CAPN6	calpain 6	0.014
ADRA2A	adrenergic, alpha-2A-, receptor	0.014
ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	0.014
WNT5B	wingless-type MMTV integration site family, member 5B	0.014
FBN1	fibrillin 1	0.014
SIM2	single-minded homolog 2 (Drosophila)	0.013
LHFP	lipoma HMGIC fusion partner	0.013
RAB23	RAB23, member RAS oncogene family	0.013
KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3	0.013
FZD2	frizzled homolog 2 (Drosophila)	0.013	Human Rat
EPHA3	EPH receptor A3	0.013
BFSP1	beaded filament structural protein 1, filensin	0.013
LZTFL1	leucine zipper transcription factor-like 1	0.013
GJA1	gap junction protein, alpha 1, 43kDa	0.013
SALL1	sal-like 1 (Drosophila)	0.013
SOSTDC1	sclerostin domain containing 1	0.013
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.013
SHISA2	shisa homolog 2 (Xenopus laevis)	0.013
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.013
TGFB2	transforming growth factor, beta 2	0.013
ZFPM1	zinc finger protein, multitype 1	0.013
HOXD9	homeobox D9	0.013
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.013
LMBR1	limb region 1 homolog (mouse)	0.013
NKX3-2	NK3 homeobox 2	0.012
FAP	fibroblast activation protein, alpha	0.012
MSX1	msh homeobox 1	0.012
DIO2	deiodinase, iodothyronine, type II	0.012
SOX21	SRY (sex determining region Y)-box 21	0.012
RASL12	RAS-like, family 12	0.012
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.012
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.012
APOD	apolipoprotein D	0.012
C10orf116	chromosome 10 open reading frame 116	0.012
FZD10	frizzled homolog 10 (Drosophila)	0.012	Human
PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	0.012
OLFML1	olfactomedin-like 1	0.012
DPT	dermatopontin	0.012
PTN	pleiotrophin	0.012
COL3A1	collagen, type III, alpha 1	0.012
SCN4B	sodium channel, voltage-gated, type IV, beta	0.012
OLFML2A	olfactomedin-like 2A	0.012
DLK1	delta-like 1 homolog (Drosophila)	0.011
OSR2	odd-skipped related 2 (Drosophila)	0.011
FOXB1	forkhead box B1	0.011
ITGA8	integrin, alpha 8	0.011
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.011
SMCR7	Smith-Magenis syndrome chromosome region, candidate 7	0.011
LMO4	LIM domain only 4	0.011
GYG2	glycogenin 2	0.011
SNCAIP	synuclein, alpha interacting protein	0.011
FNDC1	fibronectin type III domain containing 1	0.011
ZG16B	zymogen granule protein 16 homolog B (rat)	0.011
PCDH17	protocadherin 17	0.011
PPAP2B	phosphatidic acid phosphatase type 2B	0.011
LPPR4	lipid phosphate phosphatase-related protein type 4	0.011
SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.011
EPHB2	EPH receptor B2	0.011
CASQ2	calsequestrin 2 (cardiac muscle)	0.011
FGF18	fibroblast growth factor 18	0.011
WNT10A	wingless-type MMTV integration site family, member 10A	0.011
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.011
GDF10	growth differentiation factor 10	0.011
SYNPO2	synaptopodin 2	0.011
SIX2	SIX homeobox 2	0.011
MATN2	matrilin 2	0.011
C8orf84	chromosome 8 open reading frame 84	0.011
RELN	reelin	0.011
CTSK	cathepsin K	0.011
MOXD1	monooxygenase, DBH-like 1	0.011
POU3F1	POU class 3 homeobox 1	0.011
DHX34	DEAH (Asp-Glu-Ala-His) box polypeptide 34	0.010
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.010
PCNP	PEST proteolytic signal containing nuclear protein	0.010
HOXC8	homeobox C8	0.010
LRP12	low density lipoprotein receptor-related protein 12	0.010
PSEN1	presenilin 1	0.010
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.010
EFNB2	ephrin-B2	0.010
DLX5	distal-less homeobox 5	0.010
RNF150	ring finger protein 150	0.010
CDH5	cadherin 5, type 2 (vascular endothelium)	0.010
PAMR1	peptidase domain containing associated with muscle regeneration 1	0.010
FIGF	c-fos induced growth factor (vascular endothelial growth factor D)	0.010
FAM110B	family with sequence similarity 110, member B	0.010
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.010
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.010
CCDC14	coiled-coil domain containing 14	0.010
ERP27	endoplasmic reticulum protein 27	0.010
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.010