IMP

Process View

Homo sapiens

1 genes annotated in human

schwann cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "schwann cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "schwann cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.987	Zebrafish
EGFR	epidermal growth factor receptor	0.942
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.652	Zebrafish Mouse
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.326
SOX10	SRY (sex determining region Y)-box 10	0.262
YAP1	Yes-associated protein 1	0.222
PAX3	paired box 3	0.191
EGR1	early growth response 1	0.169
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.137
INADL	InaD-like (Drosophila)	0.136
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.119
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.107
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.102
EGR3	early growth response 3	0.081
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.073
GRB7	growth factor receptor-bound protein 7	0.065
MED29	mediator complex subunit 29	0.064
PARVA	parvin, alpha	0.059
JAM2	junctional adhesion molecule 2	0.057
F11R	F11 receptor	0.057
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.054
KCTD1	potassium channel tetramerisation domain containing 1	0.053
HIPK2	homeodomain interacting protein kinase 2	0.051
DMD	dystrophin	0.044
DCTN1	dynactin 1	0.042
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.042
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.041
JAM3	junctional adhesion molecule 3	0.040
HDAC6	histone deacetylase 6	0.040
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.039
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.039
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.037
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.037
SH3RF1	SH3 domain containing ring finger 1	0.035
TARBP2	TAR (HIV-1) RNA binding protein 2	0.033
DTNA	dystrobrevin, alpha	0.033
CCL14	chemokine (C-C motif) ligand 14	0.033
DDR2	discoidin domain receptor tyrosine kinase 2	0.033
SH3BP4	SH3-domain binding protein 4	0.033
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.032
PTK6	PTK6 protein tyrosine kinase 6	0.031
TNRC6A	trinucleotide repeat containing 6A	0.031
TJP3	tight junction protein 3 (zona occludens 3)	0.030
CDK19	cyclin-dependent kinase 19	0.029
TNRC6C	trinucleotide repeat containing 6C	0.029
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.029
SPRR2A	small proline-rich protein 2A	0.028
APP	amyloid beta (A4) precursor protein	0.028
PRKCZ	protein kinase C, zeta	0.028
CDH5	cadherin 5, type 2 (vascular endothelium)	0.027
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.027
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.027
FGFR1	fibroblast growth factor receptor 1	0.026
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.026
LDHA	lactate dehydrogenase A	0.025
GAB2	GRB2-associated binding protein 2	0.024
VAV3	vav 3 guanine nucleotide exchange factor	0.022
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.021
ACP5	acid phosphatase 5, tartrate resistant	0.021
CABLES1	Cdk5 and Abl enzyme substrate 1	0.021
LIMS1	LIM and senescent cell antigen-like domains 1	0.021
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.020
ANXA9	annexin A9	0.020
SMAD4	SMAD family member 4	0.020
AMOTL2	angiomotin like 2	0.020
INSR	insulin receptor	0.019
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.019
TNS3	tensin 3	0.019
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.019
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.019
PRKCI	protein kinase C, iota	0.018
MEOX2	mesenchyme homeobox 2	0.018
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.018
MAPT	microtubule-associated protein tau	0.017
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.017
HCFC1	host cell factor C1 (VP16-accessory protein)	0.016
SKIL	SKI-like oncogene	0.016
SMAD3	SMAD family member 3	0.016
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.015
PARVB	parvin, beta	0.015
ATF7IP	activating transcription factor 7 interacting protein	0.015
LAMA5	laminin, alpha 5	0.015
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.014
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.014
JUNB	jun B proto-oncogene	0.014
ZMAT3	zinc finger, matrin-type 3	0.014
ZMYM3	zinc finger, MYM-type 3	0.014
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.014
USP21	ubiquitin specific peptidase 21	0.014
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.013
VCL	vinculin	0.013
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.013
SERTAD1	SERTA domain containing 1	0.013
CCDC115	coiled-coil domain containing 115	0.013
MED15	mediator complex subunit 15	0.013
FKBP9	FK506 binding protein 9, 63 kDa	0.013
ZNF746	zinc finger protein 746	0.013
EPHB1	EPH receptor B1	0.013
FAM193A	family with sequence similarity 193, member A	0.013
AMOT	angiomotin	0.013
PRKCA	protein kinase C, alpha	0.013
LTBP3	latent transforming growth factor beta binding protein 3	0.012
POFUT1	protein O-fucosyltransferase 1	0.012
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.012
TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)	0.012
EIF2C3	eukaryotic translation initiation factor 2C, 3	0.012
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.012
ALAS1	aminolevulinate, delta-, synthase 1	0.012
SP1	Sp1 transcription factor	0.012
PRKCD	protein kinase C, delta	0.012
MED24	mediator complex subunit 24	0.012
ADCY6	adenylate cyclase 6	0.012
NCK2	NCK adaptor protein 2	0.012
BAD	BCL2-associated agonist of cell death	0.012
IER2	immediate early response 2	0.012
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.012
RSU1	Ras suppressor protein 1	0.012
DUSP23	dual specificity phosphatase 23	0.012
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.012
SNX17	sorting nexin 17	0.012
DEDD	death effector domain containing	0.012
FOXO3	forkhead box O3	0.012
MYOD1	myogenic differentiation 1	0.011
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.011
GLI3	GLI family zinc finger 3	0.011
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.011
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.011
VAV2	vav 2 guanine nucleotide exchange factor	0.011
NPIP	nuclear pore complex interacting protein	0.011
BCL6	B-cell CLL/lymphoma 6	0.011
PNPLA3	patatin-like phospholipase domain containing 3	0.011
SRCIN1	SRC kinase signaling inhibitor 1	0.011
GAB1	GRB2-associated binding protein 1	0.011
FBLN1	fibulin 1	0.011
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.011
TNS4	tensin 4	0.011
ILK	integrin-linked kinase	0.011	Mouse
DOCK1	dedicator of cytokinesis 1	0.011
MUC1	mucin 1, cell surface associated	0.011
SMAD1	SMAD family member 1	0.011
CABLES2	Cdk5 and Abl enzyme substrate 2	0.011
ZBED5	zinc finger, BED-type containing 5	0.011
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.010
CHN2	chimerin (chimaerin) 2	0.010
SH2D3A	SH2 domain containing 3A	0.010
EPAS1	endothelial PAS domain protein 1	0.010
DACH1	dachshund homolog 1 (Drosophila)	0.010
SSBP3	single stranded DNA binding protein 3	0.010
PEBP4	phosphatidylethanolamine-binding protein 4	0.010
MED25	mediator complex subunit 25	0.010
SOCS1	suppressor of cytokine signaling 1	0.010
IPO8	importin 8	0.010