IMP

Process View

Homo sapiens

12 genes annotated in human

endocytic recycling

The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "endocytic recycling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "endocytic recycling" (in gray)

Name	Description	Probability	Func Analog Organism
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.853
SYNRG	synergin, gamma	0.772
TBK1	TANK-binding kinase 1	0.530	Fly
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.518
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.491
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.421
CYLD	cylindromatosis (turban tumor syndrome)	0.398
EHD1	EH-domain containing 1	0.353
PDPK1	3-phosphoinositide dependent protein kinase-1	0.330
OPTN	optineurin	0.216
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.210
GDI2	GDP dissociation inhibitor 2	0.206
AZI2	5-azacytidine induced 2	0.198
OCRL	oculocerebrorenal syndrome of Lowe	0.191
TANK	TRAF family member-associated NFKB activator	0.167
SYK	spleen tyrosine kinase	0.164
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.158	Fly
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.156
LDOC1	leucine zipper, down-regulated in cancer 1	0.150
RPTOR	regulatory associated protein of MTOR, complex 1	0.150
AP1G1	adaptor-related protein complex 1, gamma 1 subunit	0.130
TRAF2	TNF receptor-associated factor 2	0.123
RAB1A	RAB1A, member RAS oncogene family	0.120
SCHIP1	schwannomin interacting protein 1	0.117
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.109
RAB11A	RAB11A, member RAS oncogene family	0.108
FADS2	fatty acid desaturase 2	0.092
GOLGA2	golgin A2	0.080
SORT1	sortilin 1	0.077	Human
ATF2	activating transcription factor 2	0.076
SORL1	sortilin-related receptor, L(DLR class) A repeats containing	0.075
RAD18	RAD18 homolog (S. cerevisiae)	0.068
RAB8A	RAB8A, member RAS oncogene family	0.067	Human
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.063
ANKFY1	ankyrin repeat and FYVE domain containing 1	0.061
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.060	Fly
MTF1	metal-regulatory transcription factor 1	0.059
EXOC4	exocyst complex component 4	0.058
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.058
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.055
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.052
RAB5A	RAB5A, member RAS oncogene family	0.051
IRF3	interferon regulatory factor 3	0.050
TBKBP1	TBK1 binding protein 1	0.049
RAB10	RAB10, member RAS oncogene family	0.048	Human Worm
MICALL1	MICAL-like 1	0.047
IGF2R	insulin-like growth factor 2 receptor	0.045
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.045
DHCR7	7-dehydrocholesterol reductase	0.044
LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	0.042
EPS15	epidermal growth factor receptor pathway substrate 15	0.031
UBASH3B	ubiquitin associated and SH3 domain containing B	0.031
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.029
TBC1D17	TBC1 domain family, member 17	0.028
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.026
MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	0.025
RNF11	ring finger protein 11	0.024
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.024
EEA1	early endosome antigen 1	0.023
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.022
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.021
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.020
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.020	Fly
CLTC	clathrin, heavy chain (Hc)	0.019
SPHAR	S-phase response (cyclin related)	0.018
M6PR	mannose-6-phosphate receptor (cation dependent)	0.018
IL4R	interleukin 4 receptor	0.018
PTRF	polymerase I and transcript release factor	0.017
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.016
SNX6	sorting nexin 6	0.016
FXR2	fragile X mental retardation, autosomal homolog 2	0.015
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.015
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.015
RAB14	RAB14, member RAS oncogene family	0.015
BIN1	bridging integrator 1	0.014
MAP7D1	MAP7 domain containing 1	0.014
TRIM23	tripartite motif containing 23	0.013
AGFG1	ArfGAP with FG repeats 1	0.013
PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme	0.013
EHD4	EH-domain containing 4	0.013
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.012
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.012
AP1B1	adaptor-related protein complex 1, beta 1 subunit	0.012
TIFA	TRAF-interacting protein with forkhead-associated domain	0.012
STON2	stonin 2	0.011
DEPTOR	DEP domain containing MTOR-interacting protein	0.011
FCHO2	FCH domain only 2	0.011
TNIP1	TNFAIP3 interacting protein 1	0.011
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.010
YTHDF3	YTH domain family, member 3	0.010
TRAF3	TNF receptor-associated factor 3	0.010
BLNK	B-cell linker	0.010
ARF6	ADP-ribosylation factor 6	0.010