IMP

Process View

Homo sapiens

1 genes annotated in human

pulmonary vein morphogenesis

The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "pulmonary vein morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "pulmonary vein morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	1.000
TBX5	T-box 5	0.815	Human
IL2RB	interleukin 2 receptor, beta	0.485
TBX1	T-box 1	0.373	Human
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.183
MSX1	msh homeobox 1	0.164
CXCR6	chemokine (C-X-C motif) receptor 6	0.143
FASLG	Fas ligand (TNF superfamily, member 6)	0.099
PRDM8	PR domain containing 8	0.089
MXRA8	matrix-remodelling associated 8	0.084
ACAN	aggrecan	0.083
SIX2	SIX homeobox 2	0.080
PYY	peptide YY	0.076
EVX1	even-skipped homeobox 1	0.076
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.076
HOXD9	homeobox D9	0.075
HOXC11	homeobox C11	0.074
WNT1	wingless-type MMTV integration site family, member 1	0.068
HOXD12	homeobox D12	0.063
LTK	leukocyte receptor tyrosine kinase	0.062
FGF3	fibroblast growth factor 3	0.060
FOXD2	forkhead box D2	0.055
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.054
SFTPC	surfactant protein C	0.053
HOXB13	homeobox B13	0.052
FOXC1	forkhead box C1	0.051
CXCR3	chemokine (C-X-C motif) receptor 3	0.049
CD7	CD7 molecule	0.047
HOXA3	homeobox A3	0.047
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.045
FAM46A	family with sequence similarity 46, member A	0.045
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.045
DLX4	distal-less homeobox 4	0.044
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.044
COMP	cartilage oligomeric matrix protein	0.043
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.043
NGFR	nerve growth factor receptor	0.042
DLL4	delta-like 4 (Drosophila)	0.042
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.041
CD160	CD160 molecule	0.039
IRX5	iroquois homeobox 5	0.039
HOXC8	homeobox C8	0.037
GATA3	GATA binding protein 3	0.037
HOXD11	homeobox D11	0.035
FOXL1	forkhead box L1	0.035
COL2A1	collagen, type II, alpha 1	0.034
LBX1	ladybird homeobox 1	0.034
HOXA11	homeobox A11	0.034
GATA4	GATA binding protein 4	0.034
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.034
SOX1	SRY (sex determining region Y)-box 1	0.033
HOXB8	homeobox B8	0.033
SIX3	SIX homeobox 3	0.033
TLX1	T-cell leukemia homeobox 1	0.032
ATP8B3	ATPase, aminophospholipid transporter, class I, type 8B, member 3	0.031
TBX21	T-box 21	0.030	Human
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.030
LIM2	lens intrinsic membrane protein 2, 19kDa	0.030
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.029
TBX4	T-box 4	0.029	Human
NOVA2	neuro-oncological ventral antigen 2	0.029
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.028
GATA5	GATA binding protein 5	0.028
HOXA1	homeobox A1	0.028
MAPK7	mitogen-activated protein kinase 7	0.028
SOX14	SRY (sex determining region Y)-box 14	0.028
BANP	BTG3 associated nuclear protein	0.027
OAF	OAF homolog (Drosophila)	0.027
LAG3	lymphocyte-activation gene 3	0.027
KLHL35	kelch-like 35 (Drosophila)	0.027
CALCA	calcitonin-related polypeptide alpha	0.027
FOXF1	forkhead box F1	0.027
SCARF2	scavenger receptor class F, member 2	0.027
FLT4	fms-related tyrosine kinase 4	0.026
PAX3	paired box 3	0.026
NKG7	natural killer cell group 7 sequence	0.026
GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.026
SIM2	single-minded homolog 2 (Drosophila)	0.025
IFNG	interferon, gamma	0.025
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.025
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.025
IL12RB1	interleukin 12 receptor, beta 1	0.024
NKX2-8	NK2 homeobox 8	0.024
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.024
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.023
CYP2W1	cytochrome P450, family 2, subfamily W, polypeptide 1	0.023
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.023
SSC5D	scavenger receptor cysteine rich domain containing (5 domains)	0.023
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.023
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.022
TGM5	transglutaminase 5	0.022
FOXF2	forkhead box F2	0.022
GJC2	gap junction protein, gamma 2, 47kDa	0.022
OTOP2	otopetrin 2	0.022
COL13A1	collagen, type XIII, alpha 1	0.022
GCM2	glial cells missing homolog 2 (Drosophila)	0.022
BFSP2	beaded filament structural protein 2, phakinin	0.022
ADRA1D	adrenergic, alpha-1D-, receptor	0.021
VRTN	vertebrae development homolog (pig)	0.021
HOXB5	homeobox B5	0.021
PFDN1	prefoldin subunit 1	0.021
GFI1	growth factor independent 1 transcription repressor	0.021
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.021
HES2	hairy and enhancer of split 2 (Drosophila)	0.021
HOXD3	homeobox D3	0.021
FUT5	fucosyltransferase 5 (alpha (1,3) fucosyltransferase)	0.020
CRLF1	cytokine receptor-like factor 1	0.020
VAX2	ventral anterior homeobox 2	0.020
HOXA2	homeobox A2	0.020
PITX2	paired-like homeodomain 2	0.020	Mouse
S1PR2	sphingosine-1-phosphate receptor 2	0.020
PRSS21	protease, serine, 21 (testisin)	0.019
TRPC6	transient receptor potential cation channel, subfamily C, member 6	0.019
HOXD10	homeobox D10	0.019
HNF1A	HNF1 homeobox A	0.019
HOXC10	homeobox C10	0.019
LDB3	LIM domain binding 3	0.019
HMX2	H6 family homeobox 2	0.019
TXK	TXK tyrosine kinase	0.019
TCHH	trichohyalin	0.019
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.019
CCL24	chemokine (C-C motif) ligand 24	0.019
HOXD13	homeobox D13	0.019
RLN1	relaxin 1	0.019
FOXA2	forkhead box A2	0.018
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.018
PRDM12	PR domain containing 12	0.018
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.018
POU3F1	POU class 3 homeobox 1	0.018
IRX4	iroquois homeobox 4	0.018
HTR1E	5-hydroxytryptamine (serotonin) receptor 1E	0.018
PAX9	paired box 9	0.018
ADRA2B	adrenergic, alpha-2B-, receptor	0.018
CDHR5	cadherin-related family member 5	0.018
BNC1	basonuclin 1	0.018
MYOD1	myogenic differentiation 1	0.018
PVRIG	poliovirus receptor related immunoglobulin domain containing	0.018
TCF15	transcription factor 15 (basic helix-loop-helix)	0.017
SIX1	SIX homeobox 1	0.017
XCL2	chemokine (C motif) ligand 2	0.017
EN2	engrailed homeobox 2	0.017
PTGDR	prostaglandin D2 receptor (DP)	0.017
KRT31	keratin 31	0.017
GALR2	galanin receptor 2	0.017
CD6	CD6 molecule	0.017
PRAC	prostate cancer susceptibility candidate	0.016
BGLAP	bone gamma-carboxyglutamate (gla) protein	0.016
CSPG4	chondroitin sulfate proteoglycan 4	0.016
TMSB4Y	thymosin beta 4, Y-linked	0.016
FOXN4	forkhead box N4	0.016
GSC2	goosecoid homeobox 2	0.016
SRPK3	SRSF protein kinase 3	0.016
GP1BA	glycoprotein Ib (platelet), alpha polypeptide	0.016
FOXD3	forkhead box D3	0.016
SLC5A11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.016
SLAMF7	SLAM family member 7	0.016
XCL1	chemokine (C motif) ligand 1	0.016
HOXC5	homeobox C5	0.016
TKTL1	transketolase-like 1	0.016
PDE6G	phosphodiesterase 6G, cGMP-specific, rod, gamma	0.016
CLCF1	cardiotrophin-like cytokine factor 1	0.016
C22orf31	chromosome 22 open reading frame 31	0.015
HCRTR1	hypocretin (orexin) receptor 1	0.015
CHRNG	cholinergic receptor, nicotinic, gamma	0.015
ALOX15	arachidonate 15-lipoxygenase	0.015
IL1RAPL1	interleukin 1 receptor accessory protein-like 1	0.015
PRMT8	protein arginine methyltransferase 8	0.015
CTSW	cathepsin W	0.015
FABP7	fatty acid binding protein 7, brain	0.015
UNC5C	unc-5 homolog C (C. elegans)	0.015
SHH	sonic hedgehog	0.015
POU4F1	POU class 4 homeobox 1	0.015
HTRA3	HtrA serine peptidase 3	0.015
CRTAM	cytotoxic and regulatory T cell molecule	0.015
NCR3	natural cytotoxicity triggering receptor 3	0.015
FGF6	fibroblast growth factor 6	0.015
KCNK13	potassium channel, subfamily K, member 13	0.015
AFF2	AF4/FMR2 family, member 2	0.015
NRAP	nebulin-related anchoring protein	0.015
PHOX2B	paired-like homeobox 2b	0.015
PAX2	paired box 2	0.015
SSTR5	somatostatin receptor 5	0.015
DSPP	dentin sialophosphoprotein	0.014
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.014
FGF18	fibroblast growth factor 18	0.014
DMRT3	doublesex and mab-3 related transcription factor 3	0.014
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.014
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.014
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.014
RGS9	regulator of G-protein signaling 9	0.014
CHRDL2	chordin-like 2	0.014
HOXC4	homeobox C4	0.014
SPTB	spectrin, beta, erythrocytic	0.014
GALR1	galanin receptor 1	0.014
CCKBR	cholecystokinin B receptor	0.014
IGHMBP2	immunoglobulin mu binding protein 2	0.014
HOXB1	homeobox B1	0.014
TCAP	titin-cap (telethonin)	0.014
SLAMF6	SLAM family member 6	0.014
GZMM	granzyme M (lymphocyte met-ase 1)	0.014
SOX18	SRY (sex determining region Y)-box 18	0.014
HHLA1	HERV-H LTR-associating 1	0.014
WNT3	wingless-type MMTV integration site family, member 3	0.014
HOXA7	homeobox A7	0.013
ZNF80	zinc finger protein 80	0.013
SHOX2	short stature homeobox 2	0.013
NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2	0.013
TIGIT	T cell immunoreceptor with Ig and ITIM domains	0.013
CRHR2	corticotropin releasing hormone receptor 2	0.013
ADRA2C	adrenergic, alpha-2C-, receptor	0.013
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.013
SLC5A5	solute carrier family 5 (sodium iodide symporter), member 5	0.013
MSX2	msh homeobox 2	0.013
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.013
NKX2-1	NK2 homeobox 1	0.013
GGT5	gamma-glutamyltransferase 5	0.013
IL17B	interleukin 17B	0.013
RAX	retina and anterior neural fold homeobox	0.013
LPAR4	lysophosphatidic acid receptor 4	0.013
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.013
NKX3-2	NK3 homeobox 2	0.013
IL13	interleukin 13	0.013
HOXC6	homeobox C6	0.013
PDE10A	phosphodiesterase 10A	0.013
KIF21B	kinesin family member 21B	0.013
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.013
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.013
HOXA13	homeobox A13	0.013
HOXC9	homeobox C9	0.013
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.013
IL24	interleukin 24	0.012
EYA2	eyes absent homolog 2 (Drosophila)	0.012
AATK	apoptosis-associated tyrosine kinase	0.012
KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.012
SIM1	single-minded homolog 1 (Drosophila)	0.012
KCNC4	potassium voltage-gated channel, Shaw-related subfamily, member 4	0.012
CDK3	cyclin-dependent kinase 3	0.012
MAPK4	mitogen-activated protein kinase 4	0.012
KCNIP2	Kv channel interacting protein 2	0.012
FOXL2	forkhead box L2	0.012
IL4	interleukin 4	0.012
ELN	elastin	0.012
PDE6B	phosphodiesterase 6B, cGMP-specific, rod, beta	0.012
HIST1H4G	histone cluster 1, H4g	0.012
EOMES	eomesodermin	0.012	Human
LAIR2	leukocyte-associated immunoglobulin-like receptor 2	0.012
ITGB1BP3	integrin beta 1 binding protein 3	0.012
NPTX1	neuronal pentraxin I	0.012
OPRL1	opiate receptor-like 1	0.012
CHST5	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5	0.012
LILRA4	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4	0.012
FOXJ1	forkhead box J1	0.012
SYT15	synaptotagmin XV	0.012
MAGEA4	melanoma antigen family A, 4	0.012
UBASH3A	ubiquitin associated and SH3 domain containing A	0.012
CD70	CD70 molecule	0.012
PDE6H	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.012
CPNE7	copine VII	0.012
GPR1	G protein-coupled receptor 1	0.012
GUCA1B	guanylate cyclase activator 1B (retina)	0.012
DGKQ	diacylglycerol kinase, theta 110kDa	0.012
ABO	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	0.011
KAZALD1	Kazal-type serine peptidase inhibitor domain 1	0.011
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.011
HOXD4	homeobox D4	0.011
CA10	carbonic anhydrase X	0.011
WNT6	wingless-type MMTV integration site family, member 6	0.011
WNT7A	wingless-type MMTV integration site family, member 7A	0.011
PHOX2A	paired-like homeobox 2a	0.011
C1orf94	chromosome 1 open reading frame 94	0.011
OSR1	odd-skipped related 1 (Drosophila)	0.011
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.011
SLC46A2	solute carrier family 46, member 2	0.011
ZACN	zinc activated ligand-gated ion channel	0.011
KLRC4	killer cell lectin-like receptor subfamily C, member 4	0.011
CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.011
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.011
LGR6	leucine-rich repeat containing G protein-coupled receptor 6	0.011
B4GALNT1	beta-1,4-N-acetyl-galactosaminyl transferase 1	0.011
HAPLN1	hyaluronan and proteoglycan link protein 1	0.011
HBZ	hemoglobin, zeta	0.011
GATA2	GATA binding protein 2	0.011
GPR101	G protein-coupled receptor 101	0.011
NEUROD2	neurogenic differentiation 2	0.011
KCNA7	potassium voltage-gated channel, shaker-related subfamily, member 7	0.011
CDX2	caudal type homeobox 2	0.011
UPK2	uroplakin 2	0.011
FAM70B	family with sequence similarity 70, member B	0.011
ZNF155	zinc finger protein 155	0.011
LPAR3	lysophosphatidic acid receptor 3	0.011
TBX19	T-box 19	0.011	Human
AICDA	activation-induced cytidine deaminase	0.011
SMAD6	SMAD family member 6	0.011
TCF21	transcription factor 21	0.011
KDM5D	lysine (K)-specific demethylase 5D	0.011
RBPMS2	RNA binding protein with multiple splicing 2	0.011
NKX6-1	NK6 homeobox 1	0.011
ELOVL3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.011
LIN7A	lin-7 homolog A (C. elegans)	0.011
ADRB3	adrenergic, beta-3-, receptor	0.011
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.011
HOXB4	homeobox B4	0.011
BFSP1	beaded filament structural protein 1, filensin	0.011
IHH	Indian hedgehog	0.011
TRPA1	transient receptor potential cation channel, subfamily A, member 1	0.011
GPA33	glycoprotein A33 (transmembrane)	0.011
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.011
GSTT1	glutathione S-transferase theta 1	0.011
FAM5C	family with sequence similarity 5, member C	0.011
KIAA1024	KIAA1024	0.011
CRX	cone-rod homeobox	0.011
MYO7B	myosin VIIB	0.011
GJD2	gap junction protein, delta 2, 36kDa	0.011
ERN2	endoplasmic reticulum to nucleus signaling 2	0.011
KIR2DL3	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3	0.010
TNNT3	troponin T type 3 (skeletal, fast)	0.010
MPPED1	metallophosphoesterase domain containing 1	0.010
MCOLN2	mucolipin 2	0.010
GPR4	G protein-coupled receptor 4	0.010
GPIHBP1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	0.010
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.010
CORIN	corin, serine peptidase	0.010
RPS4Y1	ribosomal protein S4, Y-linked 1	0.010
BCL2L10	BCL2-like 10 (apoptosis facilitator)	0.010
LMO1	LIM domain only 1 (rhombotin 1)	0.010
ICAM5	intercellular adhesion molecule 5, telencephalin	0.010
MAGEC1	melanoma antigen family C, 1	0.010
KRT9	keratin 9	0.010
ANKRD53	ankyrin repeat domain 53	0.010
SI	sucrase-isomaltase (alpha-glucosidase)	0.010
IL12RB2	interleukin 12 receptor, beta 2	0.010
POU4F2	POU class 4 homeobox 2	0.010
GRIK1	glutamate receptor, ionotropic, kainate 1	0.010
PNMT	phenylethanolamine N-methyltransferase	0.010
NCR1	natural cytotoxicity triggering receptor 1	0.010
GLP1R	glucagon-like peptide 1 receptor	0.010
FGF8	fibroblast growth factor 8 (androgen-induced)	0.010
HOXA6	homeobox A6	0.010