IMP

Process View

Homo sapiens

1 genes annotated in human

granzyme a production

The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "granzyme a production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "granzyme a production" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000
CCL2	chemokine (C-C motif) ligand 2	0.985	Human
CCL4	chemokine (C-C motif) ligand 4	0.977	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.976
CCL8	chemokine (C-C motif) ligand 8	0.959	Human
IDE	insulin-degrading enzyme	0.910
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.889	Human
CCL13	chemokine (C-C motif) ligand 13	0.827	Human
IL8	interleukin 8	0.780
CCL5	chemokine (C-C motif) ligand 5	0.777	Human
CXCL11	chemokine (C-X-C motif) ligand 11	0.768
CCL22	chemokine (C-C motif) ligand 22	0.757	Human
DPP4	dipeptidyl-peptidase 4	0.725
IL1B	interleukin 1, beta	0.578
CCR7	chemokine (C-C motif) receptor 7	0.536
CXCL10	chemokine (C-X-C motif) ligand 10	0.458
CCL7	chemokine (C-C motif) ligand 7	0.449	Human
IL6	interleukin 6 (interferon, beta 2)	0.396
CXCL2	chemokine (C-X-C motif) ligand 2	0.322
CCL19	chemokine (C-C motif) ligand 19	0.311	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.307
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.305
IL2RB	interleukin 2 receptor, beta	0.270
CXCL13	chemokine (C-X-C motif) ligand 13	0.244
CCL3	chemokine (C-C motif) ligand 3	0.241	Human
IFNG	interferon, gamma	0.227
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.223
CCR4	chemokine (C-C motif) receptor 4	0.208
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.204
TNF	tumor necrosis factor	0.202
CCL11	chemokine (C-C motif) ligand 11	0.198	Human
IL10	interleukin 10	0.157
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.144
CD83	CD83 molecule	0.130
CCL20	chemokine (C-C motif) ligand 20	0.115	Human
RGS1	regulator of G-protein signaling 1	0.106
IL1RN	interleukin 1 receptor antagonist	0.103
CXCL5	chemokine (C-X-C motif) ligand 5	0.099
SELE	selectin E	0.097
CCR1	chemokine (C-C motif) receptor 1	0.087
VCAM1	vascular cell adhesion molecule 1	0.087
IL7R	interleukin 7 receptor	0.082
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.077
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.073
GNLY	granulysin	0.070
FPR3	formyl peptide receptor 3	0.068
ADAMDEC1	ADAM-like, decysin 1	0.068
ICAM1	intercellular adhesion molecule 1	0.068
LAMP3	lysosomal-associated membrane protein 3	0.062
DARC	Duffy blood group, chemokine receptor	0.062
GZMK	granzyme K (granzyme 3; tryptase II)	0.061
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.056
EBI3	Epstein-Barr virus induced 3	0.051
UBD	ubiquitin D	0.047
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.043
CH25H	cholesterol 25-hydroxylase	0.043
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.043
CCL21	chemokine (C-C motif) ligand 21	0.042
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.041
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.040
SLAMF8	SLAM family member 8	0.040
IL21R	interleukin 21 receptor	0.040
ARRB1	arrestin, beta 1	0.037
CXCR3	chemokine (C-X-C motif) receptor 3	0.036
CXCR6	chemokine (C-X-C motif) receptor 6	0.035
IL2RG	interleukin 2 receptor, gamma	0.034
STAT4	signal transducer and activator of transcription 4	0.032
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.031
IL18RAP	interleukin 18 receptor accessory protein	0.030
CD80	CD80 molecule	0.030
CCL17	chemokine (C-C motif) ligand 17	0.030	Human
SLAMF7	SLAM family member 7	0.029
C1QC	complement component 1, q subcomponent, C chain	0.029
PLEK	pleckstrin	0.029
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.028
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.028
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.027
NKG7	natural killer cell group 7 sequence	0.026
INHBA	inhibin, beta A	0.026
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.026
MSC	musculin	0.025
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.024
IL32	interleukin 32	0.023
CTSW	cathepsin W	0.023
CD40	CD40 molecule, TNF receptor superfamily member 5	0.021
XCL2	chemokine (C motif) ligand 2	0.021	Human
CD69	CD69 molecule	0.020
CCL1	chemokine (C-C motif) ligand 1	0.020	Human
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.020
RGS16	regulator of G-protein signaling 16	0.020
IL1A	interleukin 1, alpha	0.020
IL10RA	interleukin 10 receptor, alpha	0.019
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.019
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.018
IRF4	interferon regulatory factor 4	0.018
CD160	CD160 molecule	0.018
C2	complement component 2	0.017
BATF	basic leucine zipper transcription factor, ATF-like	0.017
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.017
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.017
CCR3	chemokine (C-C motif) receptor 3	0.017
LAG3	lymphocyte-activation gene 3	0.017
CD163	CD163 molecule	0.016
APOC1	apolipoprotein C-I	0.016
C1QB	complement component 1, q subcomponent, B chain	0.015
ICOS	inducible T-cell co-stimulator	0.015
IL2RA	interleukin 2 receptor, alpha	0.015
SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.015
PRF1	perforin 1 (pore forming protein)	0.015
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.015
IDO1	indoleamine 2,3-dioxygenase 1	0.015
CLEC10A	C-type lectin domain family 10, member A	0.014
CCRL2	chemokine (C-C motif) receptor-like 2	0.014
CMKLR1	chemokine-like receptor 1	0.014
DNASE1L3	deoxyribonuclease I-like 3	0.014
TM7SF4	transmembrane 7 superfamily member 4	0.013
IL1R2	interleukin 1 receptor, type II	0.013
IL13	interleukin 13	0.013
SRGN	serglycin	0.013
CD209	CD209 molecule	0.013
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.013
IL1F5	interleukin 1 family, member 5 (delta)	0.012
SLAMF1	signaling lymphocytic activation molecule family member 1	0.012
BCL2A1	BCL2-related protein A1	0.012
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.012
TRAF1	TNF receptor-associated factor 1	0.012
IL11	interleukin 11	0.012
CHIT1	chitinase 1 (chitotriosidase)	0.011
PDPN	podoplanin	0.011
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.011
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.011
CD1B	CD1b molecule	0.011
C1QA	complement component 1, q subcomponent, A chain	0.011
RUNX3	runt-related transcription factor 3	0.011
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.011
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.011
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.011
LRRC32	leucine rich repeat containing 32	0.011
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.011
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.010
DUSP2	dual specificity phosphatase 2	0.010
XCL1	chemokine (C motif) ligand 1	0.010
CCL23	chemokine (C-C motif) ligand 23	0.010	Human
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.010
CCBP2	chemokine binding protein 2	0.010