IMP

Process View

Homo sapiens

17 genes annotated in human

glycolytic process

The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to ethanol, lactate, or other small molecules, or fed into the TCA cycle.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glycolytic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "glycolytic process" (in gray)

Name	Description	Probability	Func Analog Organism
ALDOA	aldolase A, fructose-bisphosphate	1.000
TPI1	triosephosphate isomerase 1	0.997	Fly
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.996	Rat
GPI	glucose-6-phosphate isomerase	0.990	Mouse
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.982
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.982	Fly
PKM2	pyruvate kinase, muscle	0.979
LDHA	lactate dehydrogenase A	0.978
ENO1	enolase 1, (alpha)	0.978	Mouse
PGK1	phosphoglycerate kinase 1	0.973	Mouse
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.970
NCOR2	nuclear receptor corepressor 2	0.914	Human
HNF4A	hepatocyte nuclear factor 4, alpha	0.801
PGAM1	phosphoglycerate mutase 1 (brain)	0.761
NCOR1	nuclear receptor corepressor 1	0.660
PPARA	peroxisome proliferator-activated receptor alpha	0.557
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.470
RARA	retinoic acid receptor, alpha	0.464
MEF2A	myocyte enhancer factor 2A	0.207
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.173
PPARG	peroxisome proliferator-activated receptor gamma	0.165	Human
ITGB1BP3	integrin beta 1 binding protein 3	0.163
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.136	Rat
RXRA	retinoid X receptor, alpha	0.130
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.123
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.112
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.099
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.094
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.094
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.093
GYS1	glycogen synthase 1 (muscle)	0.088
AGXT2	alanine--glyoxylate aminotransferase 2	0.066
ESRRG	estrogen-related receptor gamma	0.062
EGFR	epidermal growth factor receptor	0.062
BBS1	Bardet-Biedl syndrome 1	0.059
IGF1R	insulin-like growth factor 1 receptor	0.053	Human
FBP2	fructose-1,6-bisphosphatase 2	0.051	Human
BCL6	B-cell CLL/lymphoma 6	0.047
EP300	E1A binding protein p300	0.046
SP1	Sp1 transcription factor	0.045
HR	hairless homolog (mouse)	0.045
TKT	transketolase	0.045
HK1	hexokinase 1	0.043	Yeast
NCOA1	nuclear receptor coactivator 1	0.040
GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.040	Mouse
JAK2	Janus kinase 2	0.039
VEGFA	vascular endothelial growth factor A	0.036
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.035
GCKR	glucokinase (hexokinase 4) regulator	0.034
BHLHE40	basic helix-loop-helix family, member e40	0.033
IGF2R	insulin-like growth factor 2 receptor	0.032
EGLN3	egl nine homolog 3 (C. elegans)	0.031
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.031
SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.030
TUBA4A	tubulin, alpha 4a	0.030
HIPK2	homeodomain interacting protein kinase 2	0.029
ALDOC	aldolase C, fructose-bisphosphate	0.029	Human Fly
HDAC3	histone deacetylase 3	0.028
EGLN1	egl nine homolog 1 (C. elegans)	0.027
EPOR	erythropoietin receptor	0.025
STAT5A	signal transducer and activator of transcription 5A	0.024
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.024	Human
BCAR1	breast cancer anti-estrogen resistance 1	0.024
GHR	growth hormone receptor	0.024
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.024	Human
PGR	progesterone receptor	0.024
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.024
HDAC5	histone deacetylase 5	0.023
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.022
IRS2	insulin receptor substrate 2	0.022
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.022	Human
PGM1	phosphoglucomutase 1	0.021
PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.021	Rat
PFKL	phosphofructokinase, liver	0.021
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.020
PFKP	phosphofructokinase, platelet	0.020	Human
AR	androgen receptor	0.019
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.019
RUNX1	runt-related transcription factor 1	0.018
CREBBP	CREB binding protein	0.018
GAPDHS	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.018	Fly
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.018
FAF1	Fas (TNFRSF6) associated factor 1	0.018
CLEC4G	C-type lectin domain family 4, member G	0.018
MEF2C	myocyte enhancer factor 2C	0.017
IRS1	insulin receptor substrate 1	0.017
INSR	insulin receptor	0.016
ERO1L	ERO1-like (S. cerevisiae)	0.015
MLX	MAX-like protein X	0.015
C16orf45	chromosome 16 open reading frame 45	0.015
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.015
ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.015
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.014
ESR1	estrogen receptor 1	0.014
STAT5B	signal transducer and activator of transcription 5B	0.014
CDHR5	cadherin-related family member 5	0.014
PFKM	phosphofructokinase, muscle	0.014
BCKDK	branched chain ketoacid dehydrogenase kinase	0.014
PGAM2	phosphoglycerate mutase 2 (muscle)	0.014
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.013
ALDOB	aldolase B, fructose-bisphosphate	0.013
NCOA2	nuclear receptor coactivator 2	0.013
GK	glycerol kinase	0.013
NCOA6	nuclear receptor coactivator 6	0.013
RHOA	ras homolog gene family, member A	0.013
CHD9	chromodomain helicase DNA binding protein 9	0.013
CAPN1	calpain 1, (mu/I) large subunit	0.013
HCFC1	host cell factor C1 (VP16-accessory protein)	0.012
CAPNS1	calpain, small subunit 1	0.012
ADM	adrenomedullin	0.012
BBS10	Bardet-Biedl syndrome 10	0.012
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.012	Human
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.012
MIF4GD	MIF4G domain containing	0.012
LNX1	ligand of numb-protein X 1	0.012
VHL	von Hippel-Lindau tumor suppressor	0.011
ENO2	enolase 2 (gamma, neuronal)	0.011	Rat
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.011
DDB1	damage-specific DNA binding protein 1, 127kDa	0.011
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.011
PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A	0.011
POU2F1	POU class 2 homeobox 1	0.011
ING2	inhibitor of growth family, member 2	0.010
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.010
LAT	linker for activation of T cells	0.010
PILRA	paired immunoglobin-like type 2 receptor alpha	0.010